iiinova — where your digital self keeps evolving

Evan Zeitler @littlebiggloms.bsky.social · 12/05/2026

Hey, I just finished this book, Demon Copperhead. Has anyone @caulimovirus.bsky.social heard of it?

Evan Zeitler @littlebiggloms.bsky.social · 25/02/2026

Casey Means is hesitating to answer Tim Kaine when he asks her if the flu vaccine works. Disqualifying through and through. One of the least qualified people to ever be nominated.

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Duke Kidney @dukekidney.bsky.social · 13/02/2026

Sarah McLarnon, PhD (UNC) Taylor Kress, PhD (Duke) and Brendyn Miller, PhD (Wake Forest) present their research at Duke Nephrology Grand Rounds as trainees part of the NC TRIO NIH U2C/TL1 training grant

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ashley fairbanks @ziibiing.com · 27/01/2026

my expectation of democratic senators is that they find 1/10th of the bravery of your average 70 year old lutheran lady following ICE around mpls in her subaru crosstrek

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The New York Times @nytimes.com · 25/01/2026

Alex Pretti was already restrained when federal agents shot and killed him in Minneapolis, a New York Times analysis of video shows. The footage contradicts the Department of Homeland Security’s account of the shooting.

trib.al

Timeline: How the Shooting of Alex Jeffrey Pretti Unfolded

A moment-by-moment analysis of video from the scene shows that Mr. Pretti was already restrained when fatal shots were fired, which appears to contradict the federal government’s account of the event.

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Memento (spooky) Morty 🌙 @mementomorty.bsky.social · 25/01/2026

I am seeing quite a few nurses calling for a nationwide strike over the killing of Alex Pretti. I think we are seeing one of the largest workforces being radicalized before our very eyes.

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Aaron Rupar @atrupar.com · 24/01/2026

All of this is fucking senseless. Minnesota did not have an immigration problem. Trump sent his Nazi thugs here because he's racist against Somali people and to own libs like Tim Walz. Now two Minnesotans are dead and Minneapolis is on the verge of going up in flames. None. Of. This. Was. Necessary.

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onion person @junlper.beer · 24/01/2026

ICE are indistinguishable from a terrorist organization

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William Shakespeare @shakespeare.lol · 22/01/2026

are they not monsters?

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Popehat @kenwhite.bsky.social · 10/01/2026

ICE are thug scum

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the Mountain Goats @themountaingoats.bsky.social · 31/12/2025

When you get the reputation of being the guy with the encouraging words on New Year's Eve, it can start to come through as a little pressure -- what if the situation on the ground is worse than usual? what if people are more scared than they usually are, and with cause? what use are good vibes then?

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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 25/12/2025

And now with this mix - followed by a zebrafish mention @littlebiggloms.bsky.social

Zosia mentioning serotonin, dopamine, vasopressin and oxytocin - in season finale of Pluribus

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Raider @iwillnotbesilenced.bsky.social · 15/12/2025

This installation is located at a church in Charlotte.

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Thomas [DARK MODE], DO @tom.medsky.social · 19/12/2025

As a doctor I recommend the AAP childhood vaccine schedule. 😎

Wapo article from Lena Sun.

Us plans to stop recommending most childhood vaccines, defer to doctors.

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Evan Zeitler @littlebiggloms.bsky.social · 16/12/2025

"To be a Jew is to be an agent of hope in a world serially threatened by despair. Judaism is a sustained struggle against the world that is, in the name of the world that could be, should be, but is not yet." - Jonathan Sacks May we be a light in dark places. #HappyHannukah

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Evan Zeitler @littlebiggloms.bsky.social · 14/12/2025

After 5700-odd years we still have not standardized Hannukah candle size smh

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Chris Geidner @chrisgeidner.bsky.social · 13/12/2025

BREAKING: Seattle Children's Hospital successfully fought this summer to get DOJ's invasive trans care subpoena quashed. The Seattle court partially unsealed the case this week. This was the fourth, previously sealed case mentioned in this recent Law Dork report: www.lawdork.com/p/judges-doj...

IV
CONCLUSION
For these reasons, the Court GRANTS Seattle Children's motion to set aside the subpoena and motion to seal the docket. The Court ORDERS as follows:
Subpoena Duces Tecum No. 25-1431-016 is HEREBY SET ASIDE;
The docket in this action and all submittals filed thereon shall be maintained under seal;
Seattle Children's may nonetheless communicate with, and provide sealed filings to, the Washington Attorney General's Office;
The Washington Attorney General's Office may attend any sealed hearings in this proceeding; and
The Washington Attorney General's Office shall comply with this Order.
Dated this 3rd day of September, 2025.
Joha X. Chan
John H. Chun
United States District Judge

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Aaron Rupar @atrupar.com · 05/12/2025

this shit is just beyond parody, man

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Evan Zeitler @littlebiggloms.bsky.social · 03/12/2025

#NephSky as I ask every match day, what is the deal? Endocrinology and Rheumatology (what I would consider the closest comps to nephro) are following almost of their spots while we continue to...not. Do we simply have too many spots?

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jamelle @jamellebouie.net · 28/11/2025

this is just gutter racism

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Mark Peifer (He, him) @peiferlabunc.bsky.social · 19/11/2025

With ICE in the Triangle, UNC student and faculty groups are joining to demand that our Campus leadership ensure the safety of its students and staff in the face of domestic terrorism! @unc-ch-aaup.bsky.social + TransparUNCy +SUNRISE UNC

Joint Statement on U.S. Customs and Border Protection Presence at UNC-Chapel Hill
We demand that UNC Chapel Hill ensure the safety of its students and staff in the face of domestic terrorism.

With the U.S. Customs and Border Protection (CBP) entering the Triangle, issues that seemed distant are now close to home. CBP actions in Chicago, Portland, and Charlotte suggest that they know no limits. In Charlotte this week, among the over 200 abductions under the auspices of legal arrest, they dragged a US citizen out of his car after shattering his car window. Federal agents shattered car windows with the muzzle of a loaded assault rifle. CBP agents entered a church and kidnapped people in front of their children. Earlier this year, CBP agents murdered a person during a traffic stop. These actions mean that many of our UNC community members and families are now living in fear, as simply “looking Latin” can lead to detention.

International policing, border control, and other parts of the surveillance apparatus exploit racism and xenophobia to project the lens of risk onto innocent people. Under this kind of state, no one is safe, and we must protect those most vulnerable to harm. Furthermore, we know that CBP targets community members who act to protect each other, arresting people in clear violation of their rights to punish them through the judicial process. Nevertheless, we as members of the UNC community, must speak out and act to protect one another.

University leaders must unwaveringly support students, staff, and faculty—yesterday’s tepid statement from Interim Provost Dean is inadequate to meet the moment of fear and uncertainty. Interim Provost Dean reiterated that while CBP can approach individuals in public spaces, they must have a judicial warrant to enter classrooms and residence halls. The extrajudicial killing and kidnapping we have seen by CBP over the last month indicate that they will continue to ignore the law as they have been given a blank check …

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Triangle Blog Blog @triangleblogblog.bsky.social · 19/11/2025

We will not report anything without confirmation which we do independently. If you see something, the best place to call is @siembranc.bsky.social’s hotline. Also please follow them.

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Kidney International @kidneyint.bsky.social · 12/11/2025

REMODELing Mechanistic Trials for Kidney Disease: a multi-modal, tissue-centered approach to understand the renal mechanism of action of #semaglutide doi.org/10.1016/j.kint.2025.10.005 #OpenAccess #MedSky #NephSky #CKD #diabetes @uwnephrology.bsky.social @umich.edu @kidney-resrch-inst.bsky.social

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Matthew Sparks @nephrosparks.bsky.social · 06/11/2025

The 2025 #NephMadness logo dropped #kidneywk ajkdblog.org/2025/11/06/n...

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Evan Zeitler @littlebiggloms.bsky.social · 08/11/2025

If you're not at the #KidneyWk plenary this morning, you are missing @robcaliff.bsky.social absolutely putting people on notice about the real issues we face in US healthcare. Great speech.

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JAMA @jama.com · 07/11/2025

Among more than 800 000 CKD-PC participants, discordance between cystatin C and creatinine eGFR values was associated with increased risk of death, cardiovascular events, and kidney failure. #KidneyWK @asnkidney.bsky.social ja.ma/4oV4DtU

JAMA graph shows association of eGFR difference with risks of long-term adverse outcomes. Hazard ratio vs. difference between eGFRcys & eGFRcr (%). Lines for death, CVD death, heart failure, ASCVD, KFRT are plotted. Declining risk as difference approaches zero.

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Evan Zeitler @littlebiggloms.bsky.social · 07/11/2025

REMODEL is fantastic demonstration of what we can do with collaborative effort to perform what Kathy Tuttle calls mechanistic clinical trials! Semaglutide provides kidney protection via improvements in inflammation and microvascular function. Lots of data to parse going forward. #KidneyWk

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NEJM.org @nejm.org · 06/11/2025

ORIGIN phase 3 trial: In an interim analysis of a clinical trial, atacicept, a fusion protein that binds and inhibits two cytokines thought to be central to the pathophysiology of IgA nephropathy, significantly reduced proteinuria. nej.md/3JEq8QL @asnkidney.bsky.social | #KidneyWk

American Society of Nephrology Kidney Week 2025
Original Article | Nov. 6, 2025 | NEJM.org
A Phase 3 Trial of Atacicept in Patients with IgA Nephropathy

Figure 2A. Change from Baseline in 24-Hr Urinary Protein-to-Creatinine Ratio through Week 36.

The NEJM identity sits at the bottom.

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Samira Farouk MD, MSCR @ssfarouk.bsky.social · 06/11/2025

Application for #NephSIM Nephrons are due 11/13: A 6-mo virtual program for US medical students/residents interested in learning more about #nephrology & neph careers Learn more at the #KidneyWk @kidney.org @nkf-professionals.bsky.social booth in the Exhibition Hall 🫘 nephsim.com/nephsim-neph...

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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 06/11/2025

Eli Lilly continuing to hit it out the park Selective amylin agonist as an alternative to GLP1RAs? #eloralintide www.thelancet.com/journals/lan... in @thelancet.com (Yeah I know it’s #KidneyWk but what do we do till Houston wakes up!) cc @rnflex.bsky.social

Figure 2. Change in bodyweight
(A) Mean percent change in bodyweight from baseline to week 48, shown as observed means and bars indicating SEs. The model-based estimates of the mean percent change in bodyweight and differences among treatment groups at week 48 with the corresponding p values (efficacy estimand only) and 95% CIs are shown in (B) (efficacy estimand) and (D) (treatment-regimen estimand); bars indicate SEs. Multiplicity adjustment was not performed, and p values should be interpreted as exploratory. (C) shows the percentage of participants with bodyweight reductions of at least 5%, 10%, 15%, 20%, 25%, and 30% from baseline to week 48. The percentage of participants is annotated above each bar, calculated with the use of Rubin's rules by combining the percentages of participants who met the thresholds in imputed datasets. *The model-based estimates and 95% CIs from a mixed model repeated measures analysis for the efficacy estimand are shown on the right, denoted by 48.

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Evan Zeitler @littlebiggloms.bsky.social · 06/11/2025

Is watching Independence Day while I eat take out in my room for preparation for #KidneyWk? Hell yes it is! Tomorrow, let us celebrate our Independence Day...from kidney diseases!

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Evan Zeitler @littlebiggloms.bsky.social · 05/11/2025

It's been real #ObesityWeek! Thanks for letting some nephrons share your space. Off to HOU for the start of #KidneyWk on my CKM tour!

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Joe DeLong @joedelong.bsky.social · 18/10/2025

Powerful sign at No Kings in Cleveland

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Alex Chang, MD @alexchangmd.bsky.social · 16/10/2025

How do you all think ASN kidney week international attendance will be like this year? Just got an email about one of the collaborative groups. I work with having half as many as expected coming… #Tariffslawlessnessandsuch @hswapnil.medsky.social

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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 16/10/2025

The opening plenary at #KidneyWk looks phenomenal Renal RCT Renaissance is upon us (LBCT list drops tomorrow) www.asn-online.org/education/ki...

program for thursday at kidney wk

including 2 LBCTs and Vlado P talking on RCTs and curing kidney disease

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Evan Zeitler @littlebiggloms.bsky.social · 15/10/2025

Okay, I have been absentee for a while now but I had to come back for this one just to see what @hswapnil.medsky.social would say! COI: strongly prejudiced against dietary restriction in almost every form #NephJC

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Nikkolas Smith @4nikkolas.bsky.social · 10/10/2025

after millions of views and shares of my Portland Frog art. (thank you all🙏🏾) I got requests to highlight priests, and chickens, and Chicagoans, and T-Rexes, and more… all of us who refuse to bend the knee. so this is for US. 𝚂𝚝𝚊𝚗𝚍 𝚃𝚊𝚕𝚕. 𝚆𝚎 𝚆𝚒𝚕𝚕 𝚆𝚒𝚗.

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Monica Maalouf, MD @maaloufmd.bsky.social · 03/10/2025

My husband was detained by ICE today Juan Muñoz, an American citizen, father of 2, and local government official, was peacefully protesting w. other elected officials. He was assaulted and taken away I have had zero contact or updates since #SOS @duckworth.senate.gov @durbin.senate.gov

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Journal of Clinical Investigation @jci.org · 21/09/2025

ICYMI: How diet affects atherosclerosis in obesity… @aweinstock.bsky.social & team show short-term caloric restriction resolves atherosclerosis inflammation in obese mice, but weight regain accelerates its adverse effects: buff.ly/ieqwQ3O

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Ryan Marino, MD @ryanmarino.bsky.social · 16/09/2025

Casey Means, the influencer who did not complete medical training but is nominated for Surgeon General, has been extremely critical of financial conflicts of interest in medicine. But she has made hundreds of thousands shilling supplements like algae & basil seed, and from investments in big tobacco

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