A genome-wide variant effect calibration method was recently developed under the guidelines of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology (ACMG/A...

Molecular disease mechanisms caused by mutations in protein-coding regions are diverse, but they can be broadly categorised into loss-of-function (LOF), gain-of-function (GOF), and dominant-negative (...

13 January 2025 by Jeroen Dobbelaere Within research labs there are several recognisable appliances which use a considerable amount of energy. These appliances include freezers for storing samples, in...

imageimageWhile there are some options for labeling cellular neighbours, they often have low flexibility, require modification of multiple cells with different plasmids, or are otherwise technically c...