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Lori Koch

@lbkoch9.bsky.social
53 followers 81 following 1 posts

Scientist. Avid book clubber. Overly enthusiastic dancer.

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Reposted by Lori Koch
Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 21/08/2026
Excited to have this out in the world! @lacefieldlab.bsky.social and I discuss meiotic checkpoints, with a focus on how they may be tuned both in and across systems to reflect the mechanistic trade-offs, evolutionary constraints and unique goals and innovations of meiosis. 🧪
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Reposted by Lori Koch
Binyam Mogessie ቢንያም ሞገሴ @binyammogessie.bsky.social · 10/07/2026
New paper from the @xionglab.bsky.social and Mogessie labs at Yale! We uncover the molecular architecture of mammalian oocyte cytoplasmic lattices (CPLs), revealing GTP-bound tubulin associated with a degradative protein complex. Read the paper: doi.org/10.1038/s415...
doi.org
Cytoplasmic lattices store developmentally poised degradative and cytoskeletal complexes in mammalian eggs - Nature Structural & Molecular Biology
Li et al. obtain high-resolution, native structures revealing that cytoplasmic lattices in mammalian eggs organize and store degradative and cytoskeletal complexes for early embryonic development.
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Reposted by Lori Koch
Andrea Musacchio @andrea-musacchio.bsky.social · 31/07/2025
www.biorxiv.org/content/10.1...
biorxiv.org
Molecular requirements for PLK1 activation by T-loop phosphorylation
Activation of PLK1, a master mitotic kinase, requires phosphorylation of its activation segment on Thr210, within a basic consensus sequence for Aurora kinases. Aurora B-dependent phosphorylation of T...
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Lori Koch @lbkoch9.bsky.social · 19/06/2025
Awesome!! #kinetochoresforever
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Reposted by Lori Koch
Hannah Long @hannahlong.bsky.social · 05/04/2025
With many thanks to our keynote speakers - Emily Wong @em6wong.bsky.social, Manuel Irimia @mirimiam.bsky.social, Sean Munro, Sarah Teichmann, Wolfgang Baumeister and Christine Cucinotta @chrstne.bsky.social - what a fantastic couple of days of cross-cutting science, and a lively discussion session!
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Reposted by Lori Koch
Adele Marston @marstonlab.bsky.social · 26/02/2025
@lbkoch9.bsky.social and I wrote a Current Opinion piece highlighting recent progress in our understanding of centromere and kinetochore function in meiosis. www.sciencedirect.com/science/arti...
sciencedirect.com
The functional organisation of the centromere and kinetochore during meiosis
Meiosis generates gametes through a specialised cell cycle that reduces the genome by half. Homologous chromosomes are segregated in meiosis I and sis…
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