iiinova — where your digital self keeps evolving

Xiong Lab

@xionglab.bsky.social

We study host-viral interactions so our bodies can fight #coronaviruses and #HIV @Yale. RTs are not endorsements. FYI Yong doesn’t tweet, his students do!

Posts Replies Media

Xiong Lab @xionglab.bsky.social · 22/09/2026

Check out our new study: "Nsp1 From Divergent Coronaviruses has Conserved Endonuclease Activity". We show that NSP1 endonuclease activity resides in the NTD across divergent coronaviruses, while the cofactors required for this activity are not conserved, and more authors.elsevier.com/a/1no4Y54HFd...

authors.elsevier.com

000

Xiong Lab @xionglab.bsky.social · 16/09/2025

Check out our new study that provides structural insights for the clearance of HIV-infected cells using JLJ648, a novel dual-function NNRTI. We report the first structure of HIV RT homotetramer nucleated by JLJ648 that induces pyroptosis. doi.org/10.1038/s443...

010