Reposted by Laura DeardenDr. Rachel Lippert @rachellippert.bsky.social · 22/11/2025Calling on my #science network! TeamNDF is #hiring a postdoc to start in 2026! Are you fascinated by metabolism and the brain? Do you want to dig into life long impacts and the molecular cause? Learn more about the team and our research here: www.dife.de/en/research/... Please share! 🧠 🍔 💉 0912
Reposted by Laura DeardenJonny Kohl @jkohl.bsky.social · 22/10/2025Out today in Nature: We uncover a neural mechanism for the integration of two internal states - hunger and estrous state - and how this integration shapes pup-directed behaviors in mice. www.nature.com/articles/s41...nature.comIntegration of hunger and hormonal state gates infant-directed aggression - NatureCombined behavioural, circuit-level and cellular approaches are used to demonstrate how hypothalamic neurons integrate hunger and oestrous state to drive a switch in how female mice interact with pups... 26921
Laura Dearden @lauradearden.bsky.social · 17/12/2025Our new review out with @ozannelab.bsky.social exploring the current data from rodent and human studies of GLP1R agonist use in pregnancy and short/ long-term safety for mother and offspring. !https://portlandpress.com/clinsci/article/139/23/1597/236872/Incretin-receptor-agonism-during-pregnancyportlandpress.comIncretin receptor agonism during pregnancy: implications for mother and babyObesity has been described by the WHO as the largest health threat facing mankind. More than 55% of pregnancies in the United Kingdom occur in women who are overweight or living with obesity. Obesity ... 173
Reposted by Laura DeardenWomen’s Health Under the Microscope @whum-camuni.bsky.social · 24/10/2025Your blood carries more than DNA — it carries clues🩸✨. New research shows that cell-free DNA (cfDNA) could help spot preeclampsia (PE) early, giving moms and babies a safer start👩🍼. (1/3) 131
Reposted by Laura DeardenDiabetologia @diabetologiajnl.bsky.social · 09/09/2025Up front & free to read in our Sept issue #editorspicks: Measurement of brain glucose metabolism in obesity and diabetes link.springer.com/article/10.1...link.springer.comMeasurement of brain glucose metabolism in obesity and diabetes - DiabetologiaThe brain consumes a large amount of glucose to fuel its high metabolic demands. Understanding brain glucose metabolism is critical for understanding the brain’s normal physiology and the pathological... 031
Laura Dearden @lauradearden.bsky.social · 09/09/2025Having a fantastic time at DOHAD 2025 in the beautiful Buenos Aires. The best place for catching up with friends and collaborators! 050
Laura Dearden @lauradearden.bsky.social · 29/07/2025I can’t be at #ssib2025 this year but the amazing Rosanne and L are there to present their data on the impact of maternal obesity/GDM on offspring hypothalamic development, and what metformin use in pregnancy does to the fetal brain. 082
Reposted by Laura DeardenBritish Society for Neuroendocrinology @bsneuroendo.bsky.social · 21/07/2025🏆 CONGRATULATIONS to Jo Lewis, 2025 winner of the Michael Harbuz Prize! Jo will speak at #BSNBradford2025 on Glucose-dependent insulinotropic polypeptide regulates food intake and body weight via the area postrema in mice. Register: bsnbradford2025.oa-e... 032
Reposted by Laura DeardenAcademy of Medical Sciences @acmedsci.bsky.social · 02/07/2025The report calls for urgent action to: 🤰 Prioritise support during pregnancy 🍴 Ensure robust regulation of the food industry 🤝 Coordinate across govt departments i.e. food, education, urban planning and transport 123
Reposted by Laura DeardenAcademy of Medical Sciences @acmedsci.bsky.social · 02/07/2025🚨 Childhood obesity is rising at alarming rates around the world Our latest report, with Italy’s Accademia Nazionale dei Lincei, calls for early intervention to ensure healthier futures for all children 🌱 Read the report: bit.ly/46qy7tN And see our key takeaways 🧵bit.lyChild’s weight for life shaped by first 1,000 days, report health experts 145
Reposted by Laura DeardenBritish Society for Neuroendocrinology @bsneuroendo.bsky.social · 17/06/2025We've got something NEW for BSN ECRs! 🔬📹An Early Career Methodology video tutorial series Our first tutorial is an Introduction to single-cell transcriptomics by Dr Sreekala Nampoothiri. Watch: my.neuroendo.org.uk/... Not a BSN member? Join today and get access: www.neuroendo.org.uk... 011
Reposted by Laura DeardenStina Börchers, PhD @stinaborchers.bsky.social · 18/06/2025🧠🍽️ A "hunger switch" in the nose? Smelling food activates a pathway from the olfactory bulb to medial septum glutamatergic neurons in mice, triggering anticipatory satiety: making them feel full before eating. This circuit works in lean mice but is disrupted in obesity. #neuroskyence 🧪nature.comA food-sensitive olfactory circuit drives anticipatory satiety - Nature MetabolismThe authors describe a sensory circuit involving the medial septum (MS), where MS glutamatergic neurons integrate food odours to prime satiety and regulate nutrient intake. 24514
Reposted by Laura DeardenBradley Jamieson @bradleyjamieson.bsky.social · 16/06/2025🎉 Thrilled to share my postdoc work, with our preprint out now on BiorXiv here: www.biorxiv.org/content/10.1... We investigated how the juvenile brain develops the ability to carry out care behaviours towards neonates by an exciting and surprising switch in neural activity and behaviourbiorxiv.org 0163
Reposted by Laura DeardenLiisa Galea @liisagalea.bsky.social · 16/06/2025Our latest review on perimenopause menopause and hormone therapy. What key issues have we missed and how can we do better from education to research to clinical care. With Laura Gravelsins! www.cambridge.org/core/journal...cambridge.orgOne size does not fit all: how type of menopause and hormone therapy matters for brain health | The British Journal of Psychiatry | Cambridge CoreOne size does not fit all: how type of menopause and hormone therapy matters for brain health 0115
Reposted by Laura DeardenIonel Sandovici @isandovici.bsky.social · 04/06/2025Very cool paper connecting nutrition, epigenetics and developmental biology. rdcu.be/eptl7rdcu.beMaternal iron deficiency causes male-to-female sex reversal in mouse embryosNature - Iron-deficient conditions in pregnant mice can cause XY mouse embryos to develop female rather than male genitalia, revealing that iron metabolism has a role in determining male sex in mice. 194
Reposted by Laura DeardenMeenakshi Asokan @meenakshiasokan.bsky.social · 30/05/2025Stoked to share our new review on why neuroendocrinology needs a systems lens and why hormones should matter to systems neuroscience. It’s time for serious cross-talk! 1235
Reposted by Laura DeardenRyanLab_TCD @ryanlab.bsky.social · 30/04/2025It was fantastic to have @labliston.bsky.social give a talk at the @mrc-mbu.bsky.social on building a positive research culture. Valuable for all investigators/group leaders regardless of career stage, check out the resources below: listonlab.uk/careers/listonlab.ukTranslational Immunology - CareersBecoming a Scientist 044
Reposted by Laura DeardenAlessandro Bartolomucci Lab @bartolomuccilab.bsky.social · 25/04/2025Food insecurity drives obesity and adiposity, but how is unclear. A recent study by @clemmensenc.bsky.social developed a mouse model for this phenomenon lnkd.in/d8pEp2qv Happy to share a commentary written with @johnspeakman4.bsky.social with our take on that study doi.org/10.1002/oby....doi.orgScarce and unpredictable, yet obesogenic: modeling the impact of food insecurity on adiposity in miceClick on the article title to read more. 175
Laura Dearden @lauradearden.bsky.social · 25/04/2025Two pics from cycling around Cambridge this week. I really want to know what animal is being transported around in that basket! 110
Reposted by Laura DeardenNature @nature.com · 24/04/2025Neurons involved in forming memories of a cold environment communicate with the part of the brain that regulates metabolic responses to cold stress go.nature.com/4lP2EHago.nature.comMemories of a cold place trigger bodily responses to warm upNeurons involved in forming memories of a cold environment communicate with the part of the brain that regulates metabolic responses to cold stress. 05117
Reposted by Laura DeardenMadhu Pai, MD, PhD @madhupai.bsky.social · 23/04/2025NIH cancels its first and largest study centered on women www.science.org/content/arti...science.orgNIH cancels its first and largest study centered on womenThe Women’s Health Initiative has produced numerous influential findings 8128109
Reposted by Laura DeardenJeremy Berg @jeremymberg.bsky.social · 21/04/2025The report with the underlying data for the Washington Post story about firings of disproportionate numbers of women and underrepresented minorities from NIH Boards of Scientific Counselors. docs.google.com/document/d/1...docs.google.comLetter_to_CongressApril16_2025_updatedApril 16, 2025 (updated 4/21/2025) Senate Committee on Health, Education, Labor and Pensions House Committee on Energy and Commerce - Subcommittee on Health Washington, DC 20510 Report: Scientists... 15743
Laura Dearden @lauradearden.bsky.social · 17/04/2025What a terrible loss to the field of obesity research and global health in general. 072
Reposted by Laura DeardenOrange Dick Tater Hater @realbiscuitspaw.bsky.social · 11/04/2025 290185012931
Reposted by Laura DeardenCarlos Guardia @charlyguardia.bsky.social · 08/04/2025NIH PostBac program is open again! And I will be hiring! #JobPostComing www.training.nih.gov/research-tra...training.nih.gov 24838
Reposted by Laura DeardenBaptiste Lacoste @blacoste.bsky.social · 26/02/2025Very cool new paper showing that Ago2 gene in glutamatergic neurons is critical for the formation of cerebral blood vessels in the developing mouse brain 🤩 #cerebrovascularscience.orgGlutamatergic argonaute2 promotes the formation of the neurovascular unit in miceNeurovascular unit formation is mediated by Ago2-dependent repression of PTEN in excitatory neurons. 0196
Reposted by Laura DeardenOregon 🕎🎲 @oregonthedm.bsky.social · 09/04/2025Biggest commitment to a 3 second joke I've ever seen 8869107428433
Reposted by Laura DeardenDr Kate Womersley @katewomersley.com · 09/04/2025If you want to learn more about MESSAGE and how to get involved in our work, you can follow us here @messagetgi.bsky.social , and on our website www.messageproject.co.uk 0167
Reposted by Laura Deardenallen institute @alleninstitute.org · 09/04/2025How does the brain work? Scientists are closer to the answer with the largest wiring diagram and functional map of a mammalian brain to date. 🧵 🧠📈 1431179
Laura Dearden @lauradearden.bsky.social · 09/04/2025More children are drawing women scientists than ever before. Good! Although these children also assume a level of PPE that is not common among most scientists I know! www.science.org/content/arti...science.orgWhat does a scientist look like? Children are drawing women more than ever beforeStudy is based on 20,860 sketches drawn by children over 5 decades 041
Reposted by Laura DeardenJames Russ-Silsby @jamesr-s.bsky.social · 04/04/2025There are fewer than 10 documented genetic causes of Transient Neonatal Diabetes (TNDM) and now PAX4 is one of them! Really proud of this collaborative work done between the Neonatal Diabetes Research Team at Exeter and the Translational Genomics of Diabetes Lab in Stanford. 0118
Reposted by Laura DeardenMehdi Hasan @mehdirhasan.bsky.social · 04/04/2025The two most powerful Republican politicians in America - the president and co-president of the United States - are publicly praising and defending and excusing the crimes of a far-right foreign politician who leads a party founded by a Holocaust-denying neo-Nazi. We are in a very, very dark place. 46570871954
Reposted by Laura DeardenSchool of Biological Sciences @cambridgebiosci.bsky.social · 02/04/2025A great opportunity for postdoctoral scientists from Black Heritage backgrounds! Join the online session on 8 April to find out more ⬇️ 042
Laura Dearden @lauradearden.bsky.social · 25/03/2025Fun lab dinner last night. We ate about 10kg of sushi between us 😂 071
Reposted by Laura DeardenDaniel Drucker @danieljdrucker.bsky.social · 20/03/2025A conserved role of m6A signaling in arcuate nucleus neurogenesis in mice and human organoids shedding light on the developmental basis of epitranscriptomic regulation of food intake and energy homeostasis #obesity #RNA @cellcellpress.bsky.social www.cell.com/cell-stem-ce...cell.comm6A deficiency impairs hypothalamic neurogenesis of feeding-related neurons in mice and human organoids and leads to adult obesity in miceShen et al. revealed a conserved role of Mettl14/Ythdc1-dependent m6A signaling in arcuate nucleus neurogenesis of feeding-related neurons in mice and human organoids. Furthermore, deletion of Mettl14... 021
Reposted by Laura DeardenPeter Sagal @petersagal.bsky.social · 11/03/2025This letter appeared in the Bloomsburg PA Press Enterprise this morning. I am assured the writer is who he purports to be, an Air Force veteran. 1064261979576
Reposted by Laura DeardenTomás Ryan @tjryan.bsky.social · 12/03/2025What are we talking about, when we talk about 'representations'? My undergraduate student, Oyinkansola Olorunleke, is conducting a thesis project on the concept of representation in cognitive sciences & neuroscience. We are seeking interested participants in the below survey: tinyurl.com/2e6rcnxvtinyurl.comRepresentation: Past, Present & FutureThis questionnaire is for a final year neuroscience student who is doing her capstone as part of the Representation: Past, Present & Future Project at Trinity College Dublin. 32230
Reposted by Laura DeardenDaniel Fazakerley @dfazakerley.bsky.social · 12/03/2025We have a postdoc position available in our team to undertake a UKRI-funded project to develop a new cultured skeletal muscle model for studying glc metabolism and insulin action. www.jobs.cam.ac.uk/job/50597/ @ims-mrl.bsky.social Please RT. Please email if interested.jobs.cam.ac.ukPost-doctoral Research Associate (Fixed Term) - Job Opportunities - University of CambridgePost-doctoral Research Associate (Fixed Term) in the Department of Clinical Biochemistry at the University of Cambridge. 277
Reposted by Laura DeardenTristan Yates @tristansyates.bsky.social · 11/03/2025Last year, I was overjoyed to receive an NIH NRSA fellowship to study toddler brains and caregiving effects on memory at Columbia. Last night, my grant was terminated. 821002370
Laura Dearden @lauradearden.bsky.social · 11/03/2025It's not just the hypothalamus that is sensitive to changes in nutrition during development 👀 020
Reposted by Laura DeardenNC3Rs @nc3rs.bsky.social · 11/03/2025We are halfway through The Togeth3R Consortium’s webinar series and 1,600 people from 42 different countries have joined us to hear about non-animal approaches in fields associated with high levels of animal use. Watch the webinar recordings: nc3rs.org.uk/3rs-resource...nc3rs.org.ukNon-animal approaches across EuropeA webinar series from The Togeth3R Consortium of European 3Rs centres showcasing non-animal methods. 165
Reposted by Laura DeardenSchool of Biological Sciences @cambridgebiosci.bsky.social · 08/03/2025Read our final reflections from our inspiring Women in Leadership positions across the School of Biological Sciences this International Women’s Day (and make sure to check out our other posts!) #IWD2025 #InternationalWomensDay 053
Reposted by Laura DeardenInstitute of Metabolic Science-Metabolic Research Laboratories @ims-mrl.bsky.social · 08/03/2025For International Women’s Day, we are celebrating the women of the @ims-mrl.bsky.social, the @mrcepid.bsky.social and GDAR Network. Meet Agnes Lukasik, Patient and Public Involvement and Engagement (PPIE) Manager at the IMS-MRL 👉 www.mrl.ims.cam.ac.uk/staff/agnes-... #AccelerateAction #IWD2025 061
Reposted by Laura DeardenCathy Abbott @cathyabbott.bsky.social · 06/03/2025I spent yesterday interviewing candidates for a DEI related scheme. They had all faced barriers but were utterly inspiring. This is just *stupid* as well as evil. "NIH staff members ..cancel grants for projects studying ... (DEI) in the scientific workforce" www.nature.com/articles/d41...nature.comExclusive: NIH to terminate hundreds of active research grantsStudies that touch on LGBT+ health, gender identity and DEI in the biomedical workforce could be terminated, according to documents obtained by Nature. 0153
Reposted by Laura DeardenCatherine Dulac @dulaclab.bsky.social · 05/03/2025After last week publication from the lab on circuits of social isolation/satiety, today we publish a different line of research by @harriskaplan.bsky.social et al., on the development trajectories of hypothalamic POA cell types driving survival and social behavior. www.nature.com/articles/s41...nature.comSensory input, sex and function shape hypothalamic cell type development - NaturePaired transcriptomic and chromatin accessibility profiling are used to examine the developmental trajectories of neuronal populations in the hypothalamic preoptic region, including cell types with ke... 15719
Reposted by Laura DeardenSebastien G Bouret @sebastienbouret.bsky.social · 05/03/2025Another successful eprObes consortium meeting in Brussels, where we discussed our progress in identifying early risk factors for obesity and intervention/prevention strategies 🇪🇺 @ec.europa.eu @neuroendolille.bsky.social 052
Reposted by Laura DeardenInstitute of Metabolic Science-Metabolic Research Laboratories @ims-mrl.bsky.social · 04/03/2025Researchers at the @ims-mrl.bsky.social are trying to understand how signals between the mother and baby in pregnancy cause increased obesity risk, & whether changes in pregnancy eg increased exercise, can stop the inter-generational transmission of obesity risk. 👇 doi.org/10.1098/rstb... 013