iiinova — where your digital self keeps evolving

Reposted by Kris Kilian

epithelial mechanics fan club @epimechfc.bsky.social · 23/11/2025

The interfacial geometry of the epithelium has direct mechanical effects on cancer cells. In regions of higher tension, cancer cells acquire stem cell properties. This was demonstrated in 3D cultures of multiples shapes using melanoma cells. @kriskilian.bsky.social buff.ly/GYlyEBH

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Reposted by Kris Kilian

Emily R. Trunnell, Ph.D. @ertrunnell.bsky.social · 04/11/2025

In this review, @gsilvani.bsky.social, Martina Stenzel, & @kriskilian.bsky.social of @nanomed-unsw.bsky.social discuss how advances in #organoids & perfusable MPS are transforming nanoparticle design & accelerating nanodrug development by enabling more predictive assessments of efficacy.

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Kris Kilian @kriskilian.bsky.social · 08/09/2025

Interested in mechanical forces influencing phenotype plasticity? Check out our latest work, led by Giulia Silvani, where we used microfluidic models to explore #melanoma cells transiting tight spaces—constriction induced invasiveness and tumorigenicity… www.nature.com/articles/s41...

nature.com

Capillary constrictions prime cancer cell tumorigenicity through PIEZO1 - Nature Communications

Cancer cells can squeeze through confined spaces and undergo nuclear deformation, leading to changes in chromatin organisation. Here, the authors show that mechanical constriction in microcapillaries ...

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Kris Kilian @kriskilian.bsky.social · 27/07/2025

Work needs to be tempered with play. Some of my best ideas have come from introspective mountain time. I thought I needed a new ski jacket, but alas @nanomed-unsw.bsky.social had me covered 🤩 #acn #nanomedicine #treblecone #wanaka 🇳🇿🏂❄️

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Kris Kilian @kriskilian.bsky.social · 06/07/2025

Hot off the press! Exploring phenotype plasticity in confined spheroids @nanomed-unsw.bsky.social Interfacial Stress Regulates Plasticity and Drug Resistance at the Breast Cancer‐Host Interface - Soliman - Advanced Science - Wiley Online Library advanced.onlinelibrary.wiley.com/doi/10.1002/...

advanced.onlinelibrary.wiley.com

Interfacial Stress Regulates Plasticity and Drug Resistance at the Breast Cancer‐Host Interface

Drop-on-demand printing is used to replicate the spatial compartmentalization of the breast cancer-host interface. Hydrogel confinement affects phenotypic changes in cells at the spheroid interface t...

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Reposted by Kris Kilian

Andrew Holle @ahcells.bsky.social · 24/06/2025

Interested in a #postdoc on nuclear #mechanobiology? We have a fully funded position in the Confinement Mechanobiology Lab designed to help you meet your career goals while researching the rapidly growing field of cellular #confinement. Please get in touch for more info!

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Kris Kilian @kriskilian.bsky.social · 24/06/2025

Check out our latest paper —a new approach to pore analysis in hydrogels Decoding Hydrogel Porosity: Advancing the Structural Analysis of Hydrogels for Biomedical Applications - Tolentino - Advanced Healthcare Materials - Wiley Online Library advanced.onlinelibrary.wiley.com/doi/full/10....

advanced.onlinelibrary.wiley.com

Decoding Hydrogel Porosity: Advancing the Structural Analysis of Hydrogels for Biomedical Applications

Porosity governs transport mechanics in hydrogels, yet characterization in its native state remains challenging. This work harnesses particle tracking to uncover three-dimensional pore geometric feat...

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Reposted by Kris Kilian

UNSW Australian Centre for NanoMedicine (ACN) @nanomed-unsw.bsky.social · 17/06/2025

A great first morning session yesterday to kick off our 15th International Nanomedicine Conference. We had an outstanding talk from our first plenary speaker, Chris Porter, and our keynote and invited speakers.

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Reposted by Kris Kilian

UNSW Australian Centre for NanoMedicine (ACN) @nanomed-unsw.bsky.social · 18/06/2025

Day 2 of our International #Nanomedicine Conference. We kicked off with a great plenary from Kate Schroder showcasing her work on #inflammasomes. Followed by more fantastic talks. #drugdelivery #biosensors @mknanomedicine.bsky.social @kriskilian.bsky.social @yingzhu.bsky.social

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Reposted by Kris Kilian

UNSW Australian Centre for NanoMedicine (ACN) @nanomed-unsw.bsky.social · 08/05/2025

Prof Kris Kilian @kriskilian.bsky.social a SMART CRC CI & co-Director of the Australian Centre for NanoMedicine, said that he hopes the SMART CRC will provide opportunities for future projects, where ideas from the lab can become real life treatments and products. www.unsw.edu.au/news/2025/05...

unsw.edu.au

UNSW and partners to receive millions to transform regenerative medicine

The University of New South Wales will be a key beneficiary of a $65 million government grant aimed at making Australia a regenerative medicine powerhouse.

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Reposted by Kris Kilian

Peter Wich - Wichlab @peterwich.bsky.social · 22/04/2025

Great talks in the #cancer session at #ASBTE2025 in Brisbane by Sara Romanazzo and Bram Soliman from the Lab of @kriskilian.bsky.social on 3D tissue models for cancer-associated fibroblasts and the mimicry of cancer-cell interfaces. @asbte.bsky.social #biopolymers #hydrogels #bioprinting

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Kris Kilian @kriskilian.bsky.social · 17/03/2025

I am looking forward to working with @msde.rsc.org as Associate Editor —consider submitting your latest and greatest work in molecular systems design and engineering 🧪🥼 🧫 🤩

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Reposted by Kris Kilian

ChemComm @chemcomm.rsc.org · 04/03/2025

#RSCPoster gets underway in less than 4 hours over on LinkedIn. For 24 hours you can see posters from hundreds of researchers across the globe on topics from all areas of chemistry. Find out more at www.rsc.org/our-events/r...

rsc.org

RSC Poster: a global online poster conference

#RSCPoster is a global poster conference that brings the chemistry community together online over the course of 24 hours

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Kris Kilian @kriskilian.bsky.social · 29/01/2025

We have been exploring polymer mechanochemistry to promote dynamic activities in hydrogel biomaterials. In this new paper, we integrated 2 responsive linkages into PEG-based hydrogels, where force and light were used as triggers to change chemistry. Check it out! pubs.rsc.org/en/content/a...

pubs.rsc.org

Multi-step functionalization of hydrogels through mechano- and photo-responsive linkages

Patterning soft materials with cell adhesion motifs can be used to emulate the structures found in natural tissues. While patterning in tissue is driven by cellular assembly, patterning soft materials...

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Kris Kilian @kriskilian.bsky.social · 24/01/2025

Kicking off 2025 with a Coogee beach BBQ —great to hang out with these legends outside of the lab….maybe a new group meeting spot 🧐🏝️ 🥳

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Kris Kilian @kriskilian.bsky.social · 11/01/2025

We developed a simple and effective way to instil some viscoelasticity, durability and bioactivity in PEG-based hydrogels, through inclusion of a self-assembling peptide network. These peptides are are an awesome additive to expand hydrogel functionality! 🤩 pubs.rsc.org/en/content/a...

pubs.rsc.org

Improving the bioactivity and mechanical properties of poly(ethylene glycol)-based hydrogels through a supramolecular support network

Most synthetic hydrogels are formed through radical polymerization to yield a homogenous covalent meshwork. In contrast, natural hydrogels form through mechanisms involving both covalent assembly and ...

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Kris Kilian @kriskilian.bsky.social · 08/01/2025

Congrats to Dr. Vina Putra @vpmechbio.bsky.social for the publication of—not 1 but 2–of her research articles….a double header going into 2025! 🥳 Vina did a fabulous PhD between my lab and Melissa Knothe-Tate, exploring cellular mechanoadaptation

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Kris Kilian @kriskilian.bsky.social · 16/12/2024

Thoughtful gift from the team. What a beautiful assortment of science images 😍 #microscopy #biomaterials #happyholidays

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Kris Kilian @kriskilian.bsky.social · 13/12/2024

I really enjoyed visiting Singapore this week for #ICBME2024. The meeting at #NUS had >700 delegates from >30 countries. Honoured to give a keynote in #Mechanobiology and invited talk in #TumorEngineering, but the best bit was catching up with old friends and making new ones….oh, and chile 🦀 🤤

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Reposted by Kris Kilian

Elizabeth Cosgriff-Hernandez @cosgriffhernandez.bsky.social · 05/12/2024

Wonderful time at MRS 3D Bioinspired Biomaterials symposium

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Reposted by Kris Kilian

Stu Cantrill @stuartcantrill.com · 04/12/2024

🚨 JOB OPENING 🚨 We are seeking a new Chief Editor for @naturesynthesis.bsky.social 🧪 📍 Beijing, New York or Shanghai 🗓️ Closing date: Dec 31, 2024 ✉️ DMs open for questions 🙏 Re-posts very much appreciated! springernature.wd3.myworkdayjobs.com/SpringerNatu... #Chemsky #Editorial #Publishing

media.tenor.com

a cartoon of two bears applying to jobs

Alt: A cartoon of a panda typing on a computer with a brown bear pacing in the background. At the top it says 'applying to jobs'.

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Kris Kilian @kriskilian.bsky.social · 02/12/2024

Just arrived into Boston for #MRS2024 #MRSfallMeeting —lucky to catch the end of #ChadMirkin talk on nanoparticle superlattices

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Reposted by Kris Kilian

Izzy Jayasinghe @ijayas.bsky.social · 01/12/2024

Reading the paper in Cell about how to close the scissor plots in gender representation at senior academic positions, I feel just a touch of pessimism. Having reached a level of seniority (middle management) I didn’t think I ever would, I read these great ideas wanting more, much more /1.

cell.com

Closing the scissor-shaped curve: Strategies to promote gender equality in academia

Gender inequality in STEM fields remains pervasive and undermines the ability for talented individuals to excel. Despite advances, women still encounter obstacles in pursuing academic careers and reac...

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Reposted by Kris Kilian

Monica Ohnsorg, Ph.D. @monicaohnsorg.bsky.social · 10/11/2024

Calling all polymer scientists! Let’s re-find each other as people continue to migrate over! Please tag people in the comments and share! I’ll continue updating as we find more people. #polymers go.bsky.app/AgjxzFa

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Reposted by Kris Kilian

Christophe Le Clainche @actin-paris-saclay.bsky.social · 14/11/2024

The Institute for Integrative Biology of the Cell (I2BC) is seeking to recruit new group leaders in cell biology. The application deadline is February 28, 2025 www.i2bc.paris-saclay.fr

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Reposted by Kris Kilian

Jon Beves @jonbeves.bsky.social · 15/11/2024

I posted it on the dying bird, but the coverage of our results about disgusting 'tar balls' made international news in the past week! If you saw it where you are, let me know or post a link below! #ozchem #chemsky theconversation.com/black-balls-...

theconversation.com

Black balls on Sydney beaches are likely ‘fatbergs’ showing traces of human faeces, methamphetamine and PFAS: new analysis

When lumps of black goop washed up Sydney’s beaches, an oil spill was the initial suspect – but a detailed chemical analysis points to sewage as the likely source.

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Reposted by Kris Kilian

Wendy Bickmore @wbickmor.bsky.social · 12/11/2024

Interested in difficult to access parts of genetics, cellular & structural biology? Join us in Edinburgh 2-4th April 2025 for "Hidden Cell, Dark Genome" Regulation in the dark genome Uncharted proteins, RNA complexity Atomic structures at cellular scale Cell diversity www.ed.ac.uk/c/hidden-cel...

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Kris Kilian @kriskilian.bsky.social · 11/11/2024

So great to see bluesky populate so rapidly —I figured it would take aeons to connect with peeps (bleeps? 😳), having migrated last week, but starter packs to the rescue!!! 👏🙌 Quick intro time…

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Reposted by Kris Kilian

Gautam Dey @gautamdey.bsky.social · 11/11/2024

So happy to see that energy and community vibe from the early days in the old place, looks like #SciSky is reaching critical mass 😍 Reporting for duty with tales of the weird and wonderful cell biology you never knew you needed to know 🫡 🧪🌏🦠

ExM image of Coscinodiscus diatom, DNA/tubulin/pyrenoid/chloroplast

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Reposted by Kris Kilian

Santiago Correa, PhD (he/him) @santicorreaphd.bsky.social · 09/11/2024

Biomaterials people, let me know you're out there so I can keep adding to the pack!!!

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Kris Kilian @kriskilian.bsky.social · 09/11/2024

First post here! Hoping we can bring back the positive scientific sharing ecosystem that was Xed. Sharing my groups latest photo for a start.

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Reposted by Kris Kilian

Prof. Brian Aguado @brianaguado.bsky.social · 08/11/2024

Anyone else divorcing Twitter? @santicorreaphd.bsky.social started a Biomaterials Starter Pack to find folks in our community! Follow this growing list of #biomaterials and #tissueengineering researchers!! go.bsky.app/DymaVAp

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