iiinova — where your digital self keeps evolving

Koen Rademaker @krademaker.bsky.social · 23/09/2026

Recommended read that also asks bigger questions about the relationship between human-specific cortical expansion and the onset of ADHD, depression and anxiety.

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Koen Rademaker @krademaker.bsky.social · 23/09/2026

We contributed to map enriched cell types in developing brain proliferating progenitors (cortical size) and postmitotic neurons (ADHD) share a spatiotemporally regulated neurogenic gene programme, using in 10x Genomics Visium data.

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Koen Rademaker @krademaker.bsky.social · 22/05/2026

Honoured to have received the Trainee Award for my talk together with @drjimmylee.bsky.social at the International Conference on Genomics and Systems Biology of Human Disease and Aging (@aegeanconf.bsky.social), with strong @bayraktarlab.bsky.social presence to showcase our spatial omics research.

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Reposted by Koen Rademaker

Hilary Martin @hilarycmartin.bsky.social · 25/02/2026

I have an opening for a staff scientist or bioinformatician in my group at the Sanger Institute (closing date 24 March). Our current projects focus on disentangling rare and common variant contributions to rare neurodevelopmental conditions and to neurodevelopmental and perinatal traits. 1/2

sanger.wd103.myworkdayjobs.com

Bioinformatician/Staff Scientist in Medical Genomics

Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity’s greatest challenge...

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Danai Vagiaki @danaivagiaki.bsky.social · 08/02/2026

Delighted to present Latent Interaction Variational Inference (LIVI), a framework for trans-eQTL mapping at single-cell resolution that I developed during my PhD together with colleagues from @steglelab.bsky.social 1/n

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Koen Rademaker @krademaker.bsky.social · 29/01/2026

The webinar series on spatial transcriptomics analysis is now open for registration! Join me on 18 March to learn how we at @bayraktarlab.bsky.social integrate single-cell and spatial transcriptomics to map the rules of neurological conditions.

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Koen Rademaker @krademaker.bsky.social · 11/11/2025

Beyond excited to share my first work with Omer's group at Sanger! With amazing co-authors Alexander & Fani we are passionate about neurodevelopmental genetics and this work really showed us the power of uncovering new genetics with spatial transcriptomics! 🧵👇 Background / motivation / key results

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Reposted by Koen Rademaker

Bas van Steensel lab (NKI) @basvansteensellab.bsky.social · 02/09/2025

Very proud of our paper on "scrambling-by-hopping" LADs, which was just published: www.nature.com/articles/s41.... Congrats to Lise Dauban and the rest of the team – this was a real tour-de-force!

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Koen Rademaker @krademaker.bsky.social · 30/06/2025

Bayraktar, Bassett and Lotfollahi labs are studying how neurodegenerative diseases (ALS, PD, AZ) spatially organise 🧠🧬 Join us to generate & analyse wealths of Xenium data: - Tech specialist: sanger.wd103.myworkdayjobs.com/en-US/Wellco... - AI postdoc: sanger.wd103.myworkdayjobs.com/en-US/Wellco...

sanger.wd103.myworkdayjobs.com

Technical Specialist: Neurodegenerative Disease Spatial Transcriptomics and Data Generation

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Reposted by Koen Rademaker

Manu Saraswat @manusaraswat.bsky.social · 16/05/2025

🧠 Excited to share my main PhD project! We mapped the regulatory rules governing Glioblastoma plasticity using single-cell multi-omics and deep learning. This work is part of a two-paper series with @bayraktarlab.bsky.social @oliverstegle.bsky.social and @moritzmall.bsky.social, Preprint at end🧵👇

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Omer Ali Bayraktar @bayraktarlab.bsky.social · 16/05/2025

How does tumour heterogeneity arise? How can we predict cancer cell plasticity? In 2 new studies, we trace #glioblastoma heterogeneity to a spatial cancer cell trajectory w. multimodal cell atlassing bit.ly/4mkrWgs & predict plasticity w. snRNA/ATAC+deep learning bit.ly/3FbI6Ic 🧵

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Reposted by Koen Rademaker

Erick Armingol @erickarmingol.bsky.social · 15/05/2025

I’m happy to share that our scCellFie manuscript is finally on bioRxiv — a project that was an amazing opportunity to return to my roots in metabolism! We infer metabolic activity from single-cell & spatial transcriptomics 🧬 Read the pre-print here👇 📄 doi.org/10.1101/2025...

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Reposted by Koen Rademaker

Lucía Barbadilla Martínez @luciabarmar.bsky.social · 14/05/2025

Our review "Predicting gene expression from DNA sequence using deep learning models" is finally out! 🤗

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Jimmy Lee @drjimmylee.bsky.social · 12/03/2025

Thrilled to share our new @naturecomms.bsky.social study with @sam-n-barnett.bsky.social on early vs late #COVID19 lung damage 🫁. Using single-cell & histopathology-informed #SpatialTranscriptomics, we uncovered key biomarkers & immune patterns. Thanks to collaborators, UKCIC & @humancellatlas.org

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Koen Rademaker @krademaker.bsky.social · 03/03/2025

Another great computational method out of the Bayraktar lab! Alexander Aivazidis has been a great colleague in our lab and it's amazing to see the capstone of his PhD is now published.

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Koen Rademaker @krademaker.bsky.social · 01/03/2025

And the talented PhD student Feri from @mhaniffa.bsky.social’s lab is running for Refuge: supporting women and their children to overcome the impact of domestic abuse. www.justgiving.com/page/feri-to...

justgiving.com

Feri's fundraiser for Refuge

Help Feri Torabi raise money to support Refuge

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Koen Rademaker @krademaker.bsky.social · 01/03/2025

Next weekend I will run the Cambridge half marathon with @sangerinstitute.bsky.social colleagues 🏃‍♂️ Two amazing people are running for charities, please support them!

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Reposted by Koen Rademaker

Anshul Kundaje @anshulkundaje.bsky.social · 04/12/2024

This is really horrific. These single cell reference atlases are widely used as is to train all kinds of models! This is one of the reasons I've constantly harping about uniform reprocessing & extremely careful QC of large atlases. 1/

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