iiinova — where your digital self keeps evolving

Reposted by Jimmy Lee

Omer Ali Bayraktar @bayraktarlab.bsky.social · 11/11/2025

Which human brain circuits are implicated in neurodevelopmental conditions? We bridged human genetics, spatial transcriptomics and neurodevelopment to discover the convergence of autism-associated genes in the developing human thalamus! www.biorxiv.org/content/10.1...

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Jimmy Lee @drjimmylee.bsky.social · 30/06/2025

📢 @bayraktarlab.bsky.social & colabs at @sangerinstitute.bsky.social are assembling the @opentargets.org funded Neuroimmune Team 🧠🧬-Leverage AI to uncover neurodegeneration Tech Spec: sanger.wd103.myworkdayjobs.com/en-US/Wellco... Postdoc AI: sanger.wd103.myworkdayjobs.com/en-US/Wellco...

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Jimmy Lee @drjimmylee.bsky.social · 12/06/2025

Very excited to see this work comes out ad preprint! An elegant strategy discovering novel recessive signals in Exome sequencing dataset of the British South Asian population 🧬 #bioinformatics #exome #DNA #datascience #genomics #genetics

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Reposted by Jimmy Lee

Lisa Sikkema @lisasikkema.bsky.social · 03/06/2025

Analyzing your single-cell data by mapping to a reference atlas? Then how do you know the mapping actually worked, and you’re not analyzing mapping-induced artifacts? We developed mapQC, a mapping evaluation tool www.biorxiv.org/content/10.1... from the ‪@fabiantheis lab. Let’s dive in🧵

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Jimmy Lee @drjimmylee.bsky.social · 31/05/2025

Amazing work by the GBM-SPACE team atlassing one of the deadliest cancers #glioblastoma at multimodality, & coupled the elegant scDORI framework. These studies reveal a high-resolution spatiotemporal cell trajectory from tumour heterogeneity & plasticity at both cellular and molecular levels

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Jimmy Lee @drjimmylee.bsky.social · 15/05/2025

Ever wondered what a snapshot of single-cell/spatial dataset can reveal? scCellFie - a scalable tool that goes beyond gene expression, making metabolic analysis possible 3-2-1, Say GENES 🤳 PREPRINT: doi.org/10.1101/2025... DOWNLOAD: sccellfie.readthedocs.io #DataScience #Bioinformatics #Spatial

sccellfie.org

Metabolic Task Visualizer

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Reposted by Jimmy Lee

Human Cell Atlas @humancellatlas.org · 26/03/2025

We are delighted to announce a new collaboration between HCA and @UNESCO.org to help advance open science, global capacity and ethical frameworks to deliver the benefits of genomics at a global scale. www.humancellatlas.org/news/the-hum...

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Jimmy Lee @drjimmylee.bsky.social · 19/03/2025

Absolutely over the moon to share our COVID-19 study is now featured on @naturecomms.bsky.social Editors’ Highlights for Microbiology & Infectious Diseases! Huge thanks to Sonja Schmid for choosing our work as one of the 50 BEST papers in this field. 💡Check it out: www.nature.com/collections/...

nature.com

Microbiology and infectious diseases

This page highlights recent articles on all aspects of bacteriology, mycology, parasitology and virology, covering the biology of pathogens, host-pathogen ...

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Reposted by Jimmy Lee

Josie Bryant @josiebryant.bsky.social · 12/03/2025

If you have experience in sc/spatial transcriptomics with an interest in microbes....come and join our team as a computational postdoc: sanger.wd103.myworkdayjobs.com/WellcomeSang... Incredibly exciting datasets on host-microbe interactions in the lung. Pls RT and reach out if you are interested.

sanger.wd103.myworkdayjobs.com

Postdoctoral Fellow - Computational

Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity’s greatest challenge...

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Jimmy Lee @drjimmylee.bsky.social · 12/03/2025

Thrilled to share our new @naturecomms.bsky.social study with @sam-n-barnett.bsky.social on early vs late #COVID19 lung damage 🫁. Using single-cell & histopathology-informed #SpatialTranscriptomics, we uncovered key biomarkers & immune patterns. Thanks to collaborators, UKCIC & @humancellatlas.org

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Jimmy Lee @drjimmylee.bsky.social · 05/12/2024

It was a pleasure to give a talk at the #HCA2024Asia @humancellatlas.org meeting. I really enjoyed catching up with some @sangerinstitute.bsky.social alumni and had some fascinating discussions with amazing scientists!! #HumanCellAtlas #Neuroscience #SingleCell #Bioinformatics

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