From @vw1234.bsky.social with our contributions in @bayraktarlab.bsky.social:
- MR finds genetically predicted
reduced cortical size to have modest but causal links to ADHD
- New spatiotemporal neurogenesis gene program enriches for polygenic effects of both traits
www.medrxiv.org/content/10.6...
medrxiv.org
Polygenic effects on cortical size and ADHD converge on a mid-gestational progenitor-to-neuron transition programme
Neurodevelopmental and psychiatric conditions have long been hypothesised to emerge from changes in the structure and function of the brain. However, the molecular and cellular mechanisms linking brai...