npj Biomedical Innovations - Engineering macrophages for cancer immunotherapy: emerging insights and therapeutic potential

npj Biomedical Innovations - Engineering macrophages for cancer immunotherapy: emerging insights and therapeutic potential

This study introduces glassy adhesion dynamics within a motor–clutch framework, revealing the mechanism by which cellular and extracellular timescales interplay and govern anomalous cancer cell migrat...

The UC San Diego School of Medicine announced the inaugural recipients of its pivot grant program, an initiative made possible by a $1 million gift from Prebys Foundation to help protect San Diego’s b...

Circulating monocytes are recruited to the tumor microenvironment, where they can differentiate into macrophages that mediate tumor progression. To...

Cytotoxic T lymphocytes and natural killer cells destroy target cells using a mechanically active cytolytic immune synapse. This Review examines the various ways in which mechanical forces contribute ...

Andreas (Andy) Acrivos passed away on February 17, 2025. Born in Greece in 1928, Prof. Acrivos arrived at Minnesota in 1950 following undergraduate studies at Syracuse University, becoming the  second...

Samples from Bennu contain the chemical building blocks of life — but with a twist.

Cell migration through narrow constrictions during cancer metastasis significantly deforms the nucleus, creating mechanical stress on chromatin. Here, the authors reveal that such chromatin deformatio...