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STEMCELL Science News @stemcellsciencenews.com · 2h

🐀 A new transplantation platform by the Pașca lab at @stanfordpsy.bsky.social neonatally engrafts the cortical cavity with human stem-cell-derived cortical organoids to generate xenocortical mice. 🔬 Read the @nature.com paper: go.nature.com/4yegEQt

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STEMCELL Science News @stemcellsciencenews.com · 3h

A new review to get you talking! 🗣️ Human #organoid and organoid‑on‑chip platforms expand the experimental toolkit for neural tube defect research and show potential for developmental toxicity assessment and patient‑specific disease modeling. | @springernature.com 🆕 bit.ly/4heOdKT

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STEMCELL Science News @stemcellsciencenews.com · 3h

Study findings in @cddpress.bsky.social identify the ESAM/Calnexin/mTOR axis as a candidate #biomarker and therapeutic vulnerability in HER2-positive #BreastCancer. Read about the research here: go.nature.com/4xLUiVg

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STEMCELL Science News @stemcellsciencenews.com · 30/09/2026

Findings from a new @cp-neuron.bsky.social study define inhibitory input as a suppressive component of the #glioma ecosystem and suggest that strengthening inhibitory tone may offer a therapeutic strategy. Read more here📕: bit.ly/4hzcD2W

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STEMCELL Science News @stemcellsciencenews.com · 30/09/2026

Presenting new work from Drs. Shira Glushakow-Smith and Kira Gritsman (@gritsmanlab.bsky.social)! @einsteinmededu.bsky.social scientists demonstrate that #AML leukemic stem cells exhibit a selective dependency on PI3Kα. #OpenAccess 🔓 Learn more: go.nature.com/4hFQfnI

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STEMCELL Science News @stemcellsciencenews.com · 30/09/2026

Hongbo Yuan and Lin Bai detail engineered bone marrow constructs tailored to model osteo-vascular niches and sustain #hematopoietic stemness, paired with thymic platforms reconstructing epithelial microenvironments for directed #lymphopoiesis. 📖 Read the review: bit.ly/4yglKeW

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STEMCELL Science News @stemcellsciencenews.com · 29/09/2026

This study published in Scientific Reports aimed to evaluate the effects of retinoic acid-treated hUC-#MSCs on #AlzheimersDisease-associated pathological and functional changes in a mouse model 🐭 of Alzheimer’s disease. 🧠 go.nature.com/4yPj9se #OpenAccess

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STEMCELL Science News @stemcellsciencenews.com · 29/09/2026

This study supports the feasibility of using virus-like particle-mediated delivery of #Cas9 ribonucleoprotein to disrupt genes of interest 🧬, enabling a more scalable and cost-effective process for generating T cell #immunotherapies. 🛡️ Learn more: bit.ly/4AxvnYg #OpenAccess

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STEMCELL Science News @stemcellsciencenews.com · 29/09/2026

🔆 New study published in @cp-cellreports.bsky.social links enhancer co-occupancy by p63/p73 to signaling and tumor maintenance in skin #SquamousCellCarcinoma. 👓 Read the #OpenAccess article: bit.ly/4iTIvk2.

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STEMCELL Science News @stemcellsciencenews.com · 25/09/2026

UV radiation drives high mutational burdens, yet precursor #melanocytes accumulate these mutations without triggering immune clearance. @harvardmed.bsky.social researchers looked at the mechanisms behind early immune evasion during #melanoma development. bit.ly/3S3rk4D

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STEMCELL Science News @stemcellsciencenews.com · 25/09/2026

In @science.org: Researchers showed that platinum-based chemotherapeutics can induce a particular mutational signature, specifically in the liver, potentially explaining some of the later adverse effects. Find out more about their study: bit.ly/4A9X750 #CancerResearch #Chemotherapeutics

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STEMCELL Science News @stemcellsciencenews.com · 24/09/2026

A new study in @cp-immunity.bsky.social reveals that an ILC2-driven serotonergic circuit contributes to asthma pathophysiology and highlights serotonergic signaling as a therapeutic target! Read more about the exciting findings here🫁: bit.ly/4xJAfrj #Asthma #PulmonaryResearch

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STEMCELL Science News @stemcellsciencenews.com · 24/09/2026

A new review synthesizes mechanistic insights linking cathepsin D-mediated proteolysis to epithelial junction reorganization and permeability barrier recovery. 📖 Learn more: bit.ly/4AgI1dS #WoundHealing #Dermatology #CellBiology

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STEMCELL Science News @stemcellsciencenews.com · 23/09/2026

A $46 million grant has been awarded to establish the Human Developmental Neurobiology Hub, co-led by Dr. Paola Arlotta from @harvardmed.bsky.social and Dr. Nenad Sestan from @yaleschoolofmed.bsky.social. Congratulations! 🧡 bit.ly/4rfv1kM

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STEMCELL Science News @stemcellsciencenews.com · 23/09/2026

New in @pnas.org! Researchers showed the critical role of CTGF+ cancer-associated #fibroblasts in pancreatic ductal #adenocarcinoma progression and position QX03-46 as a promising therapeutic candidate for targeting the fibrotic #tumor microenvironment. Read the paper here: bit.ly/4rmuYnd

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STEMCELL Science News @stemcellsciencenews.com · 22/09/2026

This review elucidates the pathophysiological mechanisms and translational potential of immune checkpoint regulation in obesity, #diabetes, and thyroid disease while proposing novel directions for clinical intervention. 📖 Explore the full #OpenAccess paper: go.nature.com/4yFGbSl

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STEMCELL Science News @stemcellsciencenews.com · 22/09/2026

📢 Muscular Dystrophy Canada announced the launch of the Neuromuscular Disease Real-World eXperience Registry! Developed with and for people living with neuromuscular disorders, their families, and caregivers, the registry responds to a long-standing gap in Canada. 🔗 bit.ly/4rlBDya

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STEMCELL Science News @stemcellsciencenews.com · 21/09/2026

🔬 Scientists from @stanfordmedicine.bsky.social and VA Palo Alto HCS investigated what drives the morphology and function of high #endothelial cells. Read how they identified adaptive endoplasmic reticulum programs that coordinate metabolic flux and organelle capacity: bit.ly/45AjORW.

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STEMCELL Science News @stemcellsciencenews.com · 18/09/2026

🧬 Exciting @nature.com article delineates the etiologies and mutational processes that drive the genomic and clinical heterogeneity of #ProstateCancer. 👓 Read how they investigated the #genomes of 959 donors: go.nature.com/4he7snZ

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STEMCELL Science News @stemcellsciencenews.com · 18/09/2026

🔬 Scientists identified functional zebrafish intestinal #StemCells in the proliferative zone of intestinal furrows that can differentiate into nearly all characterized epithelial cell lineages. Read the #OpenAccess article in @cp-cellreports.bsky.social here: bit.ly/4haXxQ2.

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STEMCELL Science News @stemcellsciencenews.com · 17/09/2026

🚨 New article in @science.org identifies the loss of oxylipin signaling as a mechanism linking #obesity and #BreastCancer. Read the work from @utah.edu here: bit.ly/4yEaclB

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STEMCELL Science News @stemcellsciencenews.com · 17/09/2026

#BrainOrganoids 🧠 can simulate critical processes of human neurodevelopment in both physiological and pathological states, providing an unprecedented window into the mechanisms and potential therapeutics of #AutismSpectrumDisorder. ▶️ Learn more: go.nature.com/46gD6MA

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STEMCELL Science News @stemcellsciencenews.com · 17/09/2026

🚨 New study in @cp-cell.bsky.social unveils a mechanism linking #cancer metabolism with cancer neuroscience and nominates guanidinoacetate synthesis as a treatment target in #gliomas! Read the full #OpenAccess article here: bit.ly/4yibjI1 🧠

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STEMCELL Science News @stemcellsciencenews.com · 16/09/2026

#GrowthFactor signals are transduced to stable transcriptional outputs by means of chromatin remodeling, DNA methylation, histone changes, and interactions with transcriptional regulatory networks to control stem cell fate. Learn more in the review: bit.ly/4h0TfKR #StemCells #Epigenetics

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STEMCELL Science News @stemcellsciencenews.com · 15/09/2026

Mixed lineage leukemia (MLL) rearrangements drive approximately 10% of acute leukemias. These findings from Dr. Wei Du's lab identify NHEJ blockade as a promising targeted therapeutic strategy for high-risk MLL-rearranged #leukemia: go.nature.com/4qSnqbC

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STEMCELL Science News @stemcellsciencenews.com · 15/09/2026

Dr. Dissanayaka and researchers established mitochondrial transfer as a vital metabolic lifeline that prevents endothelial cell collapse and drives #DentalPulpStemCell-supported #angiogenesis in the hypoxic pulp during the vulnerable window of pulpal restoration. 🦷 🔎 bit.ly/3SZ3rLY

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STEMCELL Science News @stemcellsciencenews.com · 14/09/2026

Findings define a CNS-localized adaptive immune circuit 🛡️ in #MultipleSclerosis and nominate programmable PD-1 #CART cells as a strategy to disrupt it. Learn more in @cellpress.bsky.social: bit.ly/3VqUVpG

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STEMCELL Science News @stemcellsciencenews.com · 14/09/2026

New in @cddpress.bsky.social! Findings identify CaMK4 as a critical driver of pathogenic Th17 cell response via the STAT3/RORγt axis in #psoriasis and suggest that it may represent a potential target 🎯 for further therapeutic exploration. go.nature.com/3V2FvrA

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STEMCELL Science News @stemcellsciencenews.com · 11/09/2026

📢 New research published in @science.org reveals the extent of DNA damage caused by platinum-based #chemotherapies used to treat childhood #cancer- including previously unseen effects on the #liver. Read the article here:👉 bit.ly/4A9X750

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STEMCELL Science News @stemcellsciencenews.com · 11/09/2026

Drs. Lichterfeld and Yu at the @ragoninstitute.bsky.social investigated the influence of host and viral genetic variation on HIV reservoir persistence. The study highlights how to use innate immunity for an #HIV cure. 📰 News: bit.ly/3SRlZhc ⚗️ Abstract: go.nature.com/3UBH5kd

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STEMCELL Science News @stemcellsciencenews.com · 11/09/2026

Dr. Morten Thaysen-Andersen and researchers reported on the mechanistic basis for and functional consequences of glycocalyx remodeling accompanying tumor-associated #macrophages polarization. Learn more: bit.ly/4cza9Pm

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STEMCELL Science News @stemcellsciencenews.com · 11/09/2026

Dr. Nissim Benvenisty and team uncovered the interplay between #ploidy and the #p53 pathway in determining the outcome of anticancer therapeutics. Learn more: bit.ly/3V4r1rc #OpenAccess

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STEMCELL Science News @stemcellsciencenews.com · 10/09/2026

🚨 A new study in @cp-immunity.bsky.social identifies an ILC2-driven serotonergic neuroimmune axis that contributes to #asthma pathophysiology and highlights a potential therapeutic target! 📑 Read more: bit.ly/4xJAfrj

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STEMCELL Science News @stemcellsciencenews.com · 08/09/2026

New study in @cp-cellreports.bsky.social shows that beta cells expressing insulin with chromogranin-A signal peptide can evade recognition and killing by autoreactive T cells! Read more about how this could improve stem-cell-derived therapies in #T1D: bit.ly/4gJSabC

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STEMCELL Science News @stemcellsciencenews.com · 08/09/2026

Vrije Universiteit Brussel scientists including Drs. Lauren van den Broecke, Elke De Bruyne, & Eline Menu provide an overview of T cell replenishment in #homeostasis, followed by the molecular hallmarks and signaling pathways of T cell senescence and exhaustion. 🚦 📖 📖 go.nature.com/46Dxxrr

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STEMCELL Science News @stemcellsciencenews.com · 07/09/2026

An integrated reference atlas of human skeletal muscle. 💪 Dr. Christopher Nelke and collaborators generated this atlas comprising 122,000 cells and 630,000 nuclei from 88 healthy individuals. They resolved 17 major #SkeletalMuscle cell populations. 🔗 bit.ly/466BQeJ

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STEMCELL Science News @stemcellsciencenews.com · 07/09/2026

This @cp-cellreports.bsky.social study uncovers a metabolic-epigenetic pathway that controls pathological #angiogenesis and nominates HDAC1 lactylation as a therapeutic target for #diabetic vascular complications. 🔗 bit.ly/4ic5gzk

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STEMCELL Science News @stemcellsciencenews.com · 04/09/2026

Researchers including Alexandra Nukovic show that an O2-generating platform, Click O2-CryogelVAX, targeting the tumor-associated antigen prostatic acid phosphatase, enhances adaptive immune responses, and provides therapeutic benefits in a #ProstateCancer model. 🔗 bit.ly/46GmJsF

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STEMCELL Science News @stemcellsciencenews.com · 04/09/2026

Extensive new study in @science.org identifies aberrant epithelial cell death as a hallmark of #IBD that emerges early, persists despite advanced therapies, and predicts disease relapse. Read more about this impressive work from the #UniversityofMelbourne here 👉 bit.ly/4clexRZ

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STEMCELL Science News @stemcellsciencenews.com · 03/09/2026

New study in @sigtrans-sttt.bsky.social identifies SUMOylation as a specific, druggable regulator of RAC1-driven metastatic breast cancer. 🥼Great work from the labs of Drs. Jesús Pérez-Losada & Sonia Castillo-Lluva! 📖Read more here: go.nature.com/46zEkCx

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STEMCELL Science News @stemcellsciencenews.com · 03/09/2026

Jagriti Arora and Sakshi Tiwari examine early-diverging metazoans to reevaluate the evolutionary logic of #stemness. Rather than viewing stem cells as exceptional, they argue that cellular plasticity represents a deeply conserved attribute of early life. bit.ly/4x38PLS

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STEMCELL Science News @stemcellsciencenews.com · 03/09/2026

The @yaleschoolofmed.bsky.social has received a grant of nearly $25 million from the Aligning Research to Impact Autism (@ariaroadmap.org) to map human brain development and investigate how and when autism diverges from typical development. 📰 bit.ly/4xzlGqh

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STEMCELL Science News @stemcellsciencenews.com · 01/09/2026

Rutledge Cancer Foundation is advancing a new approach to #EwingSarcoma research through its $1.5 million ACES Grant, a three-year initiative bringing together leading researchers from @JohnsHopkins and the NIH to pursue new treatment strategies. 💊 🗞️ Press Release: bit.ly/4iGA2k2

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Reposted by STEMCELL Science News

STEMCELL Technologies @stemcell.com · 01/09/2026

Dancing my way through the week 💃

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STEMCELL Science News @stemcellsciencenews.com · 28/08/2026

Researchers at the @keck.usc.edu and @uscnorriscancer.bsky.social have received two grants from the NIH totaling $7.5 million to study whether exposure to PFAS increases the risk of #LiverCancer and endometrial cancer. Learn more here: ▶️ bit.ly/4gy7xCp

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Reposted by STEMCELL Science News

Immunology Podcast @immunologypodcast.com · 28/08/2026

Scientists at @ucsfdc.bsky.social with Alyssa Indart and Huiyun Lyu discovered that engineering regulatory T cells with a self-sustaining IL-2 signaling system improves their persistence to prevent autoimmune #diabetes in mice. 🐀 🧪 bit.ly/4wtplod Listen in: bit.ly/3SQ08GQ

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Reposted by STEMCELL Science News

Nels Elde @elearlybird.bsky.social · 28/08/2026

Open your lab here at Utah! utah.peopleadmin.com/postings/208...

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STEMCELL Science News @stemcellsciencenews.com · 28/08/2026

Dr. Ana Martínez-Riaño and collaborators uncover the cellular basis of CD137-mediated suppression of #HumoralImmunity, providing insight into rational combinatorial immunotherapeutic strategies incorporating CD137 agonists under clinical development. 💊 @embojournal.org bit.ly/45YrHke

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