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kmechtler.bsky.social

@kmechtler.bsky.social
621 followers 146 following 54 posts
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kmechtler.bsky.social @kmechtler.bsky.social · 19/03/2026
If you are interested in this highly attractive position, please contact us as soon as possible. We will be conducting the first interviews shortly. www.imp.ac.at/career/open-...
imp.ac.at
Ref2605: Research Associate (Proteomics Technology Hub) | Research Institute of Molecular Pathology
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kmechtler.bsky.social @kmechtler.bsky.social · 23/02/2026
Unfortunately, no OrbiTrap Astral data is shown here. It would be really exciting...
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Chris Ashwood @cashwood.proteaglyco.com · 28/01/2026
If I remember correctly, this filled up fast last year. I expect it to be even faster this year, as Europe is becoming a more popular conference destination #teammassspec
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kmechtler.bsky.social @kmechtler.bsky.social · 28/01/2026
As last year, there is plenty of space for contributions from young scientists. We look forward to supporting you as best we can. With best regards, and on behalf of the entire organizing committee, Manuel, Fabian, Erwin and Karl
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kmechtler.bsky.social @kmechtler.bsky.social · 28/01/2026
Unfortunately, we were overbooked last year and had to close registration early. Therefore, I ask you to register as early as possible—first come, first served. As last year, we are organizing a DVP proteomics workshop on the first day, which will be led by Fabian and his team.
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kmechtler.bsky.social @kmechtler.bsky.social · 28/01/2026
It is my great honor to announce that registration for the 7th ESCP Single Cell Proteomics Conference is now open: lnkd.in/e4iyiQjf With around 250 participants, it is one of the largest SCP conferences worldwide. We are also proud to announce that there is no participation fee for our conference.
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kmechtler.bsky.social @kmechtler.bsky.social · 11/12/2025
It’s a large trumpet,…
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kmechtler.bsky.social @kmechtler.bsky.social · 25/09/2025
Why not?
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kmechtler.bsky.social @kmechtler.bsky.social · 25/09/2025
Excellent work🙂
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kmechtler.bsky.social @kmechtler.bsky.social · 28/08/2025
It is an honor to inform you that our manuscript with low resolution FAIMS is now online www.biorxiv.org/content/10.1...
biorxiv.org
Low-resolution FAIMS for increased peptide coverage in low-load and single-cell proteomics
Field Asymmetric Ion Mobility Spectrometry (FAIMS) enhances signal to noise ratio filtering ions based on their differential mobility, making it an indispensable tool for single-cell and low-input pro...
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Benjamin Furtwängler @bfurtwa.bsky.social · 22/08/2025
We’re excited to present this integrative analysis of single-cell proteomics and transcriptomics of the human HSPC hierarchy. Now published in @science.org together with @fabiantheis.bsky.social, @erwinschoof.bsky.social, @porsebo.bsky.social. www.science.org/doi/10.1126/... 🧵
science.org
Mapping early human blood cell differentiation using single-cell proteomics and transcriptomics
Single-cell transcriptomics (scRNA-seq) has facilitated the characterization of cell state heterogeneity and recapitulation of differentiation trajectories. However, the exclusive use of mRNA measurem...
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Alejandro Brenes @ajbrenes.com · 27/08/2025
Start of day 2 of the European Symposium on Single Cell Proteomics with @ryankellybyu.bsky.social telling us about high throughput proteomics towards a $10 proteome #ESCP2025
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Alejandro Brenes @ajbrenes.com · 27/08/2025
Mikaela now tells us about the scverse community intrageted ecosystem for single cell with established templates and data structures #ESCP2025
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Alejandro Brenes @ajbrenes.com · 26/08/2025
Wilfred Rossol is next talking about proteomic profiling of protein aggregates with a more spatial proteomics approach #ESCP2025
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Alejandro Brenes @ajbrenes.com · 26/08/2025
Its exciting to see that its a full house at #ESCP2025 lots of enthusiastic single cell proteomics researchers 🤓
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Alejandro Brenes @ajbrenes.com · 26/08/2025
The last session of the day is opened by Tami Geiger looking at the interactions of the immune cells with the cancer microenvironments using single cell proteomics #ESCP2025
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Alejandro Brenes @ajbrenes.com · 26/08/2025
Alexander Ivanov talking about increases in sensitivity and signal to noise when changing to ultra low flor rates for single cell proteomics. #ESCP2025
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Luke Gamon @lgamon.bsky.social · 25/08/2025
Seriously pumped for today! Deep Visual Proteomics masterclass here we come 🤓
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Alejandro Brenes @ajbrenes.com · 25/08/2025
Great from from @erwinschoof.bsky.social and his lab showing the added value of SCP!
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Vadim Demichev @vadim-demichev.bsky.social · 25/08/2025
On my way to ESCP. Super looking forward to this awesome meeting!
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Erwin Schoof @erwinschoof.bsky.social · 26/08/2025
Only a few more hours! 😃
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Alejandro Brenes @ajbrenes.com · 25/08/2025
Start of the European symposium in single cell proteomics at beautiful Viena with a workshop on spatial proteomics organised by @coscialab.bsky.social
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Alejandro Brenes @ajbrenes.com · 26/08/2025
After the DVP symposium now begins the start of the European Symposium on Single Cell Proteomics #ECSP25 A quick intro from @kmechtler.bsky.social and we kick off two days of exciting science starting with SCP of neutrophils in glioblastoma
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Alejandro Brenes @ajbrenes.com · 26/08/2025
Next up is @vadim-demichev.bsky.social telling us how quantitatively accurate is single cell proteomics #ESCP2025
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Alejandro Brenes @ajbrenes.com · 26/08/2025
Cool work from @nanopots.bsky.social doing cell surface profiling of 100-500 immine cells using affinity purification #ESCP2025
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Alejandro Brenes @ajbrenes.com · 26/08/2025
Daniela Valdes from @coscialab.bsky.social lab presents how smoking disrupts the placental function via macrophage dysregulation using single nuclei analysis and deep visual proteomics #ESCP2025
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IonOpticks @ionopticks.com · 26/08/2025
After a long trek from Melbourne, Jarrod is now on the ground in Vienna and enjoying #ESCP2025 - together with Joris, our new Business Development Manager for Europe. Stop by the IonOpticks stand and chat with Jarrod and Joris about how our new product releases can support your single-cell work.
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Alejandro Brenes @ajbrenes.com · 26/08/2025
Up next is @jwoessmann.bsky.social from the @erwinschoof.bsky.social lab showing how to focus on the exciting lower abundance proteins with single cell proteomics #ESCP2025
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Alejandro Brenes @ajbrenes.com · 26/08/2025
Next up is @pedroaragon.bsky.social talking about single cell and low input proteomics to study perturbation in leukemia #ESCP2025
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Alejandro Brenes @ajbrenes.com · 27/07/2025
Thanks to all who helped make this possible: the EMERGE team, research nurses, clinical & research collaborators & patients. @kmechtler.bsky.social @pranvera.bsky.social @patriciacoelho.bsky.social @ajmhowden.bsky.social @mas-g.bsky.social @walmsley-lab.bsky.social @edinuni-irr.bsky.social
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kmechtler.bsky.social @kmechtler.bsky.social · 17/07/2025
No
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kmechtler.bsky.social @kmechtler.bsky.social · 17/07/2025
#ESCP25: The first scientific abstracts have been submitted, and I can only say one thing—it's going to be incredibly exciting. Enclosed can you find one of our highlights presented by Ying: "Affinity purification mass spectrometry: the next frontier of single-cell and low-input proteomics".
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kmechtler.bsky.social @kmechtler.bsky.social · 17/07/2025
Breaking ESCP25 news: Ahead of the ESCP conference we will offer a Deep Visual Proteomics (DVP) workshop on August 25th 2025. Participation is free of charge, but registration is required! (www.apma.at/6thescp) Enclosed can you find the preliminary program:
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kmechtler.bsky.social @kmechtler.bsky.social · 11/07/2025
Is there an M in the peptide sequence?
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kmechtler.bsky.social @kmechtler.bsky.social · 10/07/2025
I would like to inform you that the registration deadline for our ESCP25 conference is July 27th. We are looking forward to interesting scientific contributions.
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kmechtler.bsky.social @kmechtler.bsky.social · 27/06/2025
This year's focus will extend beyond proteomics to include spatial studies on the single-cell level.
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kmechtler.bsky.social @kmechtler.bsky.social · 27/06/2025
The European Symposium on Single Cell Proteomics (ESCP) will be held in Vienna for the 6th time, from August 26th – 27th 2025 This year's focus will include spatial proteomics studies on the single-cell level. There is no registration fee Hotel rooms in Vienna are inexpensive. www.apma.at/6thescp/
apma.at
6th ESCP 2025 – APMA
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kmechtler.bsky.social @kmechtler.bsky.social · 25/06/2025
Unfortunately, no one can reproduce these experiments with this super minimalistic method part (what does high sensitive SCP mean?).
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kmechtler.bsky.social @kmechtler.bsky.social · 24/06/2025
Correct
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kmechtler.bsky.social @kmechtler.bsky.social · 22/06/2025
Would be great to get the poster 😜
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Martin Frejno @martinfrejno.bsky.social · 21/06/2025
Great presentation! Just FYI: It is a little known fact that the MS1 quantification by CHIMERYS on the MSAID Platform works by deconvoluting isotope envelopes in a similar way as JMod since the inception of the platform a year ago. If you are interested in 9-plex DIA support, feel free to reach out!
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kmechtler.bsky.social @kmechtler.bsky.social · 20/04/2025
eupa2025-stmalo.fr/en/
eupa2025-stmalo.fr
Welcome | Eupa 2025
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Chris Ashwood @cashwood.proteaglyco.com · 17/04/2025
📸
Sciex regulatory documents referring to a ZenoTOF 8600
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kmechtler.bsky.social @kmechtler.bsky.social · 09/04/2025
With great respect, I would like to congratulate all the authors for this excellent publication 😎
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kmechtler.bsky.social @kmechtler.bsky.social · 09/04/2025
Chris, agreed. It is also important to clarify how often cleaning is included in the service contract. Even if the service contract is called "LabScape complete", not everything is always included. I would ask again and renegotiate, especially when buying a new instrument.
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Chris Ashwood @cashwood.proteaglyco.com · 08/04/2025
I think we agree with each other since I said that it coats the TIMS instead of the quad? Definitely not something that can be serviced without venting but I was unaware that only Bruker can clean the TIMS cell.
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kmechtler.bsky.social @kmechtler.bsky.social · 09/04/2025
Luke, at my personal opinion, Bruker also needs some kind of filter device in the forefront. If I'm not completely mistaken, is there already a patent for this?
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kmechtler.bsky.social @kmechtler.bsky.social · 08/04/2025
After 3 weeks there is sometimes a black spot on the FAIMS electrode. FAIMS protects the system from contamination.
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kmechtler.bsky.social @kmechtler.bsky.social · 08/04/2025
apart from that, only Bruker can clean the cartridge.
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kmechtler.bsky.social @kmechtler.bsky.social · 08/04/2025
I appreciate your postings with great respect. However, I do not agree here. We had to replace the tims cartridge on our Ultra because it was no longer clean even after 3 cleaning cycles. As the system has to be ventilated each time, the effort involved is much greater,…
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