New preprint!
Deep proteome profiling for just $10/sample, all-in.
→ Single-step prep for ≤50 ng
→ 6k–8k proteins in ~10 min
→ No gain from more sample/time
Congrats to Siqi Huang, Chao Wang & Hsien-Jung Lin!
www.biorxiv.org/content/10.1...
biorxiv.org
The ten dollar proteome: low-cost, deep and quantitative proteome profiling of limited sample amounts using the Orbitrap Astral and timsTOF Ultra 2 mass spectrometers
Mass spectrometry (MS)-based proteomics remains technically demanding and prohibitively expensive for many large-scale or routine applications, with per-sample costs of hundreds of dollars or more. To...
