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Department of Molecular Biology and Genetics

@kmbg-jcu.bsky.social
79 followers 124 following 28 posts

Faculty of Science, University of South Bohemia, Czechia

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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 11/06/2026
New publication from Laboratory of Insect Immunometabolomics in collab with Laboratory of Molecular Chronobiology (@akademievedcr.bsky.social) - study shows that the firebug activates its defense mechanisms before it encounters infection or winter conditions 🌗 www.sciencedirect.com/science/arti...
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 09/05/2026
A brand-new Science Sketch has just been published in @cp-trendsbiochem.bsky.social 🎉 👉 doi.org/10.1016/j.ti... We’re especially proud that the author is one of our own PhD students Tereza Dolejšková from the Laboratory of Molecular Integrative Physiology in Drosophila ( @drosophylab.bsky.social)
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Faculty of Science, University of South Bohemia @fscusb.bsky.social · 02/04/2026
The new opinion article in Trends in Biochemical Sciences by Pavla Nedbalova and Tomas Dolezal (@drosophylab.bsky.social) from Department of Molecular Biology and Genetics (@kmbg-jcu.bsky.social) provides new insights into the complex role of adenosine! More at authors.elsevier.com/a/1msKv3S6Gf....
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 18/03/2026
We are proud to announce, that our former PhD student, Dr. Karolína Svobodová, has received Dean´s award for her outstanding PhD thesis. Congratulations on the achievment to both Karolina and her mentor Dr. Alena Krejčí (Laboratory of Bee Biology www.prf.jcu.cz/en/faculty/d...)
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Faculty of Science, University of South Bohemia @fscusb.bsky.social · 26/02/2026
Excited to share the newest publication from the Alex Bruce lab! PhD students M. Stiborová, A. Hauserová & R. Collier show that p38-MAPKs drive primitive endoderm specification in an ICM-autonomous manner, independent of cavity expansion. @kmbg-jcu.bsky.social l academic.oup.com/reproduction...
academic.oup.com
ICM-autonomous regulation of mouse blastocyst primitive endoderm formation by p38-MAPK is independent of cavity expansion
Abstract. During early mouse blastocyst ICM maturation, we previously described that pharmacological inhibition of p38-MAPK (p38-MAPKi) significantly impai
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Petr Nguyen @petrnguyen.bsky.social · 28/11/2025
Our whitepaper on #ProjectPsyche is online now in @cp-trendsecolevo.bsky.social! Psyche will generate reference genomes for all European butterflies. Just imagine what we’ll be able to learn from them. And if you can’t quite imagine it, have a look at the piece. :)
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Univerzita Karlova @unikarlova.cuni.cz · 26/11/2025
🟠 25. listopad patří Mezinárodnímu dni za odstranění násilí páchaného na ženách a dívkách. Univerzita Karlova se k této iniciativě připojila společně s dalšími institucemi a symbolicky se zahalila do oranžové. #OrangeTheWorld
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 26/11/2025
Check out the new preprint from the Laboratory of Early Mammalian Developmental Biology ( #LEMDB) from our department! 🐭
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 12/10/2025
Our department spent the weekend in Šumava for the annual PhD retreat — sharing research, ideas, and great company. Between sessions we hiked, enjoyed good food, and soaked in the autumn scenery. Thanks to everyone who made it such a great mix of work and fun! @fscusb.bsky.social
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Genome Biology and Evolution @genomebiolevol.bsky.social · 22/09/2025
Hospodářská, @petrnguyen.bsky.social et al. investigated genome size and karyotype in Polyommatus and Lysandra butterflies, rejecting polyploidy to confirm karyotypic diversification via chromosome fragmentation in Polyommatinae butterflies. 🔗 doi.org/10.1093/gbe/evaf157 #genome #evolution
GBE | Polyommatine Blue Butterflies Reveal Unexpected Integrity of the W Sex Chromosome Amid Extensive Chromosomal Fragmentation Linked to Telomere Restoration
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Nature @nature.com · 06/10/2025
BREAKING: The Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance" Stay tuned for more. #NobelPrize
A photo of a Nobel medal
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 01/10/2025
📢 Applications are OPEN for the Master’s in Functional Genetics & Bioinformatics! Learn genomics, data science & molecular biology to prepare for research & biotech careers. Apply now 👉 www.prf.jcu.cz/en/faculty/d... #Genetics #Bioinformatics #Masters #LifeSciences #Biotech
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 01/10/2025
📢 Applications are OPEN for the Master’s in Functional Genetics & Bioinformatics! Learn genomics, data science & molecular biology to prepare for research & biotech careers. Apply now 👉 www.prf.jcu.cz/en/faculty/d... #Genetics #Bioinformatics #Masters #LifeSciences #Biotech
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V4SDB @v4sdb.bsky.social · 05/09/2025
The last talk before the coffee break will be given by Lenka Gahurová from the University of South Bohemia, with a fascinating talk about Long-Term Female Fertility of African Mole-Rats #developmentalbiology #fertility #epigenetics #evodevo
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Association for Women in Science @awisnational.bsky.social · 27/08/2025
National Postdoc Appreciation Week is an annual celebration designed to recognize the significant contributions postdoctoral scholars make to US research and discovery. Join the celebration September 15-19. Visit buff.ly/NVsPBCu for a list of events both virtual and in-person. #NPAW
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 21/07/2025
PhD at Med Faculty, University of Belgrade! Study mitochondria-immune crosstalk in Parkinson’s as part of the MSCA-funded BICEPS network. Join cutting-edge neuroimmunology research! 🌍 🔗 Info: www.membranetrafficking.com/biceps/index... #PhD #Parkinsons #MSCA #neuroimmunology
membranetrafficking.com
BICEPS
Website of the MSCA doctoral network BICEPS.
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eLife @elife.bsky.social · 11/07/2025
🪰 How do insects fight infections and remember them? A new Review Article presents an overview of insect immune memory, from antiviral defences to transgenerational immunity, and the unanswered questions.
buff.ly
Current insights into insect immune memory
Insects possess a remarkable ability to develop innate immune memory, and the mechanisms underlying this process are becoming a central topic in innate immunity research.
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 07/07/2025
In their eLife (@elife.bsky.social) review, Adam Bajgar and Gabriela Krejcova examine how immune memory works against viruses and bacteria. They spotlight open questions and propose Drosophila as a model to study innate immune memory and insect vaccination. elifesciences.org/articles/105...
elifesciences.org
Current insights into insect immune memory
Insects possess a remarkable ability to develop innate immune memory, and the mechanisms underlying this process are becoming a central topic in innate immunity research.
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Faculty of Science, University of South Bohemia @fscusb.bsky.social · 01/07/2025
Immune cells don’t just fight infection—they manage the body’s energy too. A Trends in Biochemical Sciences spotlight on Nedbalova et al. shows they release adenosine, signaling other tissues to dial down energy use. sciencedirect.com/science/arti... elifesciences.org/articles/105...
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Univerzita Karlova @unikarlova.cuni.cz · 27/06/2025
Odsouzena nacisty, zavražděna komunisty. Před 75 lety byla popravena Milada Horáková, absolventka Právnické fakulty Univerzity Karlovy a česká politička. Nikdy nezapomeneme.
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Doctoral Insights Symposium @docinsightssymp.bsky.social · 24/06/2025
🚀 Curious about a PhD in life sciences? Meet EMBL at the Doctoral Insights Symposium — 100% online & free. @embl.org 🔬 Hear from PIs, students & professionals from 20 top PhD programs across Europe! 🔗 www.doctoralinsights.at #docinsights #phdprogram #lifesciences #gradschool #europe #symposium
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European Drosophila Society @fly-eds.bsky.social · 13/06/2025
And to Gabriela Krejčová, for her doctoral work entitled "The role of macrophages in the regulation of systemic metabolism in Drosophila", conducted in the lab of Adam Bajgar at the University of South Bohemia.
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Trends in Biochemical Sciences @cp-trendsbiochem.bsky.social · 18/06/2025
Online now - the Spotlight " #SAMcycle and #adenosine at the heart of immune conversations" from Tina Mukherjee and colleagues. #macrophages #infection #immunometabolism #SAMtransmethylation authors.elsevier.com/a/1lHcd3S6Gf...
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 09/06/2025
Julius Lukeš and Jiří Macas Ranked as Top Molecular Biologists in the Czech Republic @czechacademy.bsky.social www.entu.cas.cz/en/news-even...
entu.cas.cz
INSTITUTE OF ENTOMOLOGY | Julius Lukeš and Jiří Macas Ranked as Top Molecular Biologists in the Czech Republic
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 08/06/2025
Adenozin - známá molekula, na kterou se molekulární biologové z Jihočeské univerzity podívali jinou optikou. Výsledek jejich výzkumu zaujal prestižní časopis Science. Na první pohled složitý mechanismus, na druhý už nesmírně zajímavý a univerzální proces, který se děje v každém organismu.
jcu.cz
Jihočeská univerzita v Českých Budějovicích - Nový pohled na známou molekulu: pomocí adenozinu si buňka říká o víc energie. Podle jihočeských vědců to zásadně souvisí s tím, jak pracuje naše imunita
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 30/05/2025
As of today we have three new MSc. owners 🤩 Congratulations!
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 30/05/2025
PhD position in Neuroscience (4-years) on Magnetoreception! Exciting project exploring magnetoreception in insects at the CIMeC @cimecunitrento.bsky.social , University of Trento, Italy Read more: phd.unitn.it/drcimec/116/... and r.unitn.it/en/cimec/nphys contact: albrecht.haase@unitn.it
r.unitn.it
NPhys - Neurophysics Group | Gruppi e progetti di ricerca
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 29/05/2025
Congratulations to all the students who successfuly defended their bachelor thesis. Good luck for the upcoming state exams!
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 27/05/2025
PhD Student Position - Nencki Institute of Experimental Biology
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Czech Academy of Sciences @czechacademy.bsky.social · 14/05/2025
🏅 Nuclear physicist Alice Valkárová and parasitologist Julius Lukeš received honorary medals De scientia et humanitate optime meritis from the Czech Academy of Sciences yesterday, and biochemist Ivo Šafařík was awarded the Jaroslav Heyrovský Medal for Merit in the Chemical Sciences. 1url.cz/MJJY4
Nuclear physicist Alice Valkárová.Parasitologist Julius Lukeš.Biochemist Ivo Šafařík.The awarded researchers with the President of the Czech Academy of Sciences. (Left to right: Ivo Šafařík, President of the CAS Radomír Pánek, Alice Valkárová, and Julius Lukeš).
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Akademie věd ČR @akademievedcr.bsky.social · 14/05/2025
🏅Významná jaderná fyzička Alice Valkárová a oceňovaný parazitolog Julius Lukeš získali nejvyšší ocenění Akademie věd ČR De scientia et humanitate optime meritis, uznávaný biochemik Ivo Šafařík medaili Jaroslava Heyrovského za zásluhy v chemických vědách. 1url.cz/MJJY4
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 14/05/2025
Yesterday kicked off the joint Methods of Functional Genomics course by @fscusb.bsky.social and Biology centre ACRS (@czechacademy.bsky.social), featuring expert lecturers from EMBL (@embl.org). Excited for a week of cutting-edge insights and learning!
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 10/05/2025
Excited to see the work of Nedbalova et al. (@elife.bsky.social) featured in a Science dispatch! SAM metabolism and adenosine recycling shown to be central to systemic regulation & immunity. The research highlight from @tomasdolezal.bsky.social lab in @science.org www.science.org/doi/epdf/10....
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IOCB Prague @iocbprague.bsky.social · 06/05/2025
🤝 IOCB Prague is hiring – we are looking for an outstanding Junior Group Leader in Biosciences to join our vibrant scientific community. See more ► www.uochb.cz/en/open-posi... ⤵️ #openposition #iocbprague #iocb #researchjobs #biosciences
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 06/05/2025
Julius Lukeš (@czechacademy.bsky.social) is the only living scientist from the Czech Republic to become a member of National Academy of Sciences (@nasonline.org) a prestigious US institution. And he does it his own way. Congratulations! (Photo courtesy - Biologické centrum AVČR)
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GlaCerHub @glacerhub.bsky.social · 05/05/2025
🚨 PhD students in CZ/SK: Don’t miss this! JCMM just opened apps for 2025 #GlaCerHub Research Internships. 🔬 10 months at @ceitec.eu/@vut.cz & #FunGlass 💼 0.3 FTE (full-time equivalent) 📅 Deadline: June 30 Serious research, real experience. Apply now. #JCMM #HorizonEurope
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 29/04/2025
Read more about the finding from our department, that adenosine may be a central player in the mechanism that allows cells to measure their activity and require nutrients. elifesciences.org/digests/1050... @tomasdolezal.bsky.social @elife.bsky.social
elifesciences.org
Energizing immune cells
Experiments in fruit flies reveal a mechanism that immune cells can use to control the availability of nutrients when fighting infections.
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Charles University, Faculty of Science @sciencecharles.bsky.social · 26/04/2025
💊 Just graduated? EMA’s got 10-month paid traineeships! 🏫 Full-time or mix it with Erasmus+ or Ph.D. 💰 €1,942/month from October to July! 📌 Apply by 6 May: 1url.cz/qJKXZ
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 24/04/2025
Mitochondria, but make it weird. Team of V. Jurčenko and J. Lukeš (@czechacademy.bsky.social) found, that some parasites flipped the switch on how they make energy. In Vickermania, one species runs its mitochondria normally, the other lost key parts—and now runs ATP synthase in reverse. @pnas.org
doi.org
Evolutionary divergent kinetoplast genome structure and RNA editing patterns in the trypanosomatid Vickermania | PNAS
The trypanosomatid flagellates possess in their single mitochondrion a highly complex kinetoplast (k)DNA, which is composed of interlocked circular...
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Akademie věd ČR @akademievedcr.bsky.social · 22/04/2025
🌍 Dnes, na Den Země, známe vítěze The Earth prize 2025 – jsou jimi Tomáš Čermák a Anna Podmanická! Gratulujeme🎉 Více (eng)⬇️ www.avcr.cz/en/media/pre...
avcr.cz
Teen duo from Slovakia and Czechia named Global Winner for clean water solution - Akademie věd České republiky
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 22/04/2025
🐝🧬 How a fruit fly helped us understand animal clocks? Two PhD students from David Dolezel chronobiology group (@czechacademy.bsky.social) recently published in @cp-iscience.bsky.social how different species have tuned their clocks to fit their environments—and sometimes, completely rewired them.
cell.com
Coevolution of Drosophila-type Timeless with Partner Clock Proteins
Drosophila-type timeless (dTIM) is a key clock protein in fruit flies, regulating rhythmicity and light-mediated entrainment. However, functional experiments indicate that its contribution to the cloc...
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Chromatin organization and function @pecinka-grp.bsky.social · 22/04/2025
POSTDOC WANTED! Our group is looking for a postdoc to study DNA-protein crosslink repair in the heterochromatin. Apply to work on uncharacterized Arabidopsis proteins identified in the HZE genetic screen. @czechacademy.bsky.social @apecinka.bsky.social @evadt.bsky.social
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Institute of Molecular Biotechnology @imbavienna.bsky.social · 17/04/2025
👉 Apply to the Junior Group Leader position by May 18: imba.science/beagroupleader
imba.science
imba.science/beagroupleader
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Zeptej se vědce @zeptejsevedce.bsky.social · 12/04/2025
🌍 Proč vědci často zabalí kufry a frčí dělat vědu do zahraničí? Je to vůbec k něčemu dobré? ❓Na otázku od iniciativy Czexpats in Science * nám odpoví Radim👇
Zeptej se vědce Dotaz 1191 Pomáhá vědcům pobyt na jiném pracovišti?
🌍 Proč vědci často zabalí kufry a frčí dělat vědu do zahraničí? Je to vůbec k něčemu dobré? 
❓Na otázku od iniciativy Czexpats in Science * nám odpoví Radim👇
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Institute of Molecular Biotechnology @imbavienna.bsky.social · 10/04/2025
A kind reminder that the PhD Program application deadline is tomorrow.
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 09/04/2025
How a cell can measure its current activity? How does a privileged cell within an organism demand a supply of nutrients from its environment? Check out a new article from Tomáš Doležal group (@tomasdolezal.bsky.social) in @elife.bsky.social, that adenosine could be at the center of such mechanism.
elifesciences.org
SAM transmethylation pathway and adenosine recycling to ATP are essential for systemic regulation and immune response
Adenosine produced by transmethylation may act as a sensor of the balance between cell activity and nutrient supply.
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Tomas Dolezal @tomasdolezal.bsky.social · 08/04/2025
In @elife.bsky.social: SAM transmethylation pathway and adenosine recycling to ATP are essential for systemic regulation and immune response doi.org/10.7554/eLif...
doi.org
SAM transmethylation pathway and adenosine recycling to ATP are essential for systemic regulation and immune response
Adenosine produced by transmethylation may act as a sensor of the balance between cell activity and nutrient supply.
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 04/04/2025
Why humans hunt for mushrooms, and not the other way around? A study by Hassan Hashimi and his team has revealed that the Mgm1 and Opa1 proteins that form mitochondria are not true homologues, as previously thought. These differences may be key to the phenotypes we observe today. 🧬
prf.jcu.cz
Why humans hunt for mushrooms, and not the other way around? - Přírodovědecká fakulta JU
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Department of Molecular Biology and Genetics @kmbg-jcu.bsky.social · 02/04/2025
Diatoms produce up to 20% of the world's oxygen through photosynthesis 🌍✨ Research from Prof. Miroslav Obornik's lab has revealed that the process of Heme biosynthesis, which plays a crucial role in the electron transport chain in mitochondria and plastids, is highly conserved across all eukaryotes.
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Nature Reviews Neuroscience @natrevneuro.nature.com · 17/01/2025
When the ‘selfish’ brain and the ‘selfish’ immune system clash — a Journal Club by Michaela Fencková www.nature.com/articles/s41...
nature.com
When the ‘selfish’ brain and the ‘selfish’ immune system clash - Nature Reviews Neuroscience
In this Journal Club, Michaela Fencková discusses a study published in 2020 that examined the effects of acute systemic inflammation on brain glucose metabolism in the context of delirium.
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