iiinova — where your digital self keeps evolving

Mike Kalwat @kalwat.bsky.social · 12/09/2025

I'm raising money for Breakthrough T1D (new name for JDRF) to change the lives of people with type 1 diabetes. We appreciate any support. This funding aids T1D research, which is even more important now with the uncertainty surrounding traditional research funding mechanisms. p.bt1d.org/7ujvl

p.bt1d.org

Support my Breakthrough T1D Walk

Learn why I'm participating in the Breakthrough T1D Walk and raising funds to help create a world without type 1 diabetes (T1D).

020

Reposted by Mike Kalwat

@LaBonneLaB @labonnelab.bsky.social · 07/06/2025

I helped explain to the Chicago Tribune the enourmous and irrational damage the NIH funding freeze is causing at Northwestern. “You’re at risk of losing an entire next generation of scientists" "it’s terrifying; it’s completely senseless." www.chicagotribune.com/2025/06/07/w...

chicagotribune.com

Worried Northwestern lab directors describe ‘bleak’ atmosphere in wake of Trump research funding freeze

The Trump administration’s freezing of $790 million in federal research funding for Northwestern University has left concerned lab directors without key grants and forced the university to spend mi…

214983

Mike Kalwat @kalwat.bsky.social · 19/05/2025

Actin remodeling in beta cells adds new layers of upstream regulation - Congrats! @ronnyhelman.bsky.social

032

Reposted by Mike Kalwat

Jean Nakhle @jeannakhle.bsky.social · 30/04/2025

Paradoxically, both GIPR agonism and antagonism potentiate weight loss when paired with GLP-1R agonism. Two new studies in @natmetabolism.nature.com decode the different neural mechanisms employed by each strategy. Check out the #News&Views by @adriaenssenslab.bsky.social here.

113

Reposted by Mike Kalwat

Jeremy Berg @jeremymberg.bsky.social · 23/04/2025

The notice and COMMENT PERIOD OPENED TODAY AND CLOSES MAY 23. Anyone who would like to register an objection or comment should go to this page and click on the green “public comment” button at the top: www.federalregister.gov/documents/20... 6/n

federalregister.gov

Improving Performance, Accountability and Responsiveness in the Civil Service

The Office of Personnel Management (OPM) is proposing a rule to increase career employee accountability. Agency supervisors report great difficulty removing employees for poor performance or misconduc...

10113140

Mike Kalwat @kalwat.bsky.social · 06/03/2025

Just posting this starter pack for #PancSky again as I have added more people - let me know any other islet/pancreas scientists I've missed! go.bsky.app/3wdSpdi

093

Mike Kalwat @kalwat.bsky.social · 01/03/2025

Hey #PancSky and #islet people, we're hosting the 2025 Midwest Islet Club in Indianapolis May 7-8. Most of the talks are from students/postdocs. Help spread the word about abstract submission and registration! medicine.iu.edu/research-cen...

medicine.iu.edu

2025 Midwest Islet Club Meeting | Center for Diabetes and Metabolic Diseases | IU School of MedicineIndiana University School of MedicineFacebookInstagramLinkedInTwitterIndiana University School of Me...

051

Reposted by Mike Kalwat

Sarah Karlin-Smith @sarahkarlin-smith.bsky.social · 26/02/2025

Breaking: FDA's March meeting to select flu shot strains for 2025-2026 season has been canceled per email sent to committee members, a VRBPAC member told me. drug companies need about 6 months leeway to make shots in time for fall vax campaigns. #healthpolicy

41467463486

Reposted by Mike Kalwat

CantlonLab @cantlonlab.bsky.social · 18/02/2025

Join us! Science Homecoming helps scientists reconnect with communities by writing about the importance of science funding in their hometown newspapers. We’ve mapped every small newspaper in the U.S. and provide resources to get you started. Help science get back home 🧪🔬🧬 🏠 sciencehomecoming.com

sciencehomecoming.com

Science Homecoming

43905682

Reposted by Mike Kalwat

NPR @npr.org · 22/02/2025

The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.

npr.org

NIH funding freeze stalls applications on $1.5 billion in medical research funds

The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.

16135471474

Reposted by Mike Kalwat

Mark Peifer (He, him) @peiferlabunc.bsky.social · 21/02/2025

Ok scientists & those who love science 🧪: here is another exhortation. Call Congress TODAY about the freeze on NIH Council Meetings and Study Sections. Emphasize that this means NO new grants are being funded & labs will soon start to shut down and fire employees. Phone numbers are at: 5calls.org

5calls.org

5 Calls

Spend 5 minutes. Make 5 calls. Make your voice heard.

510887

Reposted by Mike Kalwat

Dawid Zyla @dzyla.bsky.social · 16/02/2025

I've been developing a semantic search tool that covers not just bioRxiv and medRxiv, but the entire PubMed database. This means you can search across a massive collection of biomedical research using keywords, questions, hypotheses, or even full abstracts. Try it out: mssearch.xyz

mssearch.xyz

Streamlit

33925217

Mike Kalwat @kalwat.bsky.social · 05/02/2025

I don't think IIDP is on Bluesky yet, so just reposting. iidp.coh.org/funding Applications Due: February 14, 2025. #islet #PancSky

051

Reposted by Mike Kalwat

Drug Monkey @drugmonkey.bsky.social · 03/02/2025

Reminder: You can always submit a grant late and include a cover letter saying why. NIH receipt and referral may take it. Or not. If you end up missing deadline because of these Commons access issues, there is this potential save move.

27225

Reposted by Mike Kalwat

Alexis A. Jourdain @jourdainlab.bsky.social · 30/01/2025

New preprint from the lab! 🚨 🧫 New galactose #CRISPR screening strategy 🎯 481 genes required for #OXPHOS ⚙️ #FAM136A in IMS proteostasis 👂Mito defects in #Menieres disease by @marcellharhai.bsky.social @fbm-unil.bsky.social A short thread 1/5 www.biorxiv.org/content/10.1...

53820

Reposted by Mike Kalwat

Song Mashup Bot @mashupbot.bsky.social · 23/01/2025

"Of Wolf and Man" by Metallica x "Fifflas" by C418

001

Mike Kalwat @kalwat.bsky.social · 17/01/2025

Will be very interesting to see how molecular biology changes in the next decade with these types of advances.

010

Reposted by Mike Kalwat

Patrick MacDonald🇨🇦 @bcellorg.bsky.social · 10/01/2025

Re-upping this paper which is ‘out’ now in this month’s issue of Cell Metab. Working with a fantastic group of collaborators, we provide a resource for exploring human islet variation in health and diabetes. www.cell.com/cell-metabolism/fullte…

03214

Mike Kalwat @kalwat.bsky.social · 28/12/2024

Happy to finally have this preprint up which represents a lot of effort from first author Gitanjali Roy and important contributions from multiple labs. I hope this work enables the discovery of cool beta cell biology related to hypersecretion.

110

Reposted by Mike Kalwat

Juan C. Landoni @jclandoni.bsky.social · 13/11/2024

Check out also @timwrhoads.bsky.social 's go.bsky.app/C2t7snh and @frezzalab.bsky.social 's go.bsky.app/VavECSX

383

Mike Kalwat @kalwat.bsky.social · 19/12/2024

Our undergrad interns in my lab at IBRI, Rachel Kuntz (#UROP) and Ini Aduroshakin (#LHSI), presented a few weeks back at the Indiana University Indianapolis Undergrad Research Conference! Rachel won an honorable mention for her poster! Thanks Andrea John and Tom Stucky for organizing.

000

Reposted by Mike Kalwat

Author Bill Sullivan @authorbillsullivan.com · 11/12/2024

Nobel Laureates Urge Senate to Turn Down Kennedy’s Nomination Elevating Mr. Kennedy to secretary of H.H.S. “would put the public’s health in jeopardy,” more than 75 laureates wrote. www.nytimes.com/2024/12/09/h...

nytimes.com

Nobel Laureates Urge Senate to Turn Down Kennedy’s Nomination

Elevating Mr. Kennedy to secretary of H.H.S. “would put the public’s health in jeopardy,” more than 75 laureates wrote.

165

Mike Kalwat @kalwat.bsky.social · 28/11/2024

Went with NY strip roast this year as a turkey/ham alternate. Great idea! #reversesear

000

Reposted by Mike Kalwat

Patrick Chovanec @prchovanec.bsky.social · 24/11/2024

My one constructive criticism on BlueSky, as a community: we need to “like” less and “retweet” more. In the absence of an algorithm, that’s the way we find each other and reward good content.

32958543506

Reposted by Mike Kalwat

Heiko Lickert @heikolickert.bsky.social · 25/11/2024

Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”. doi.org/10.1038/s422... A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social

doi.org

Inceptor binds to and directs insulin towards lysosomal degradation in β cells - Nature Metabolism

The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.

613053

Mike Kalwat @kalwat.bsky.social · 21/11/2024

Interesting - you can bridge your Bluesky account with the fediverse (aka what Mastadon uses) by following @ap.brid.gy It takes a few hours to kick in. To follow users on Mastadon, they must also have the bridge enabled though. Additional info: fed.brid.gy/docs

fed.brid.gy

Bridgy Fed

000

Reposted by Mike Kalwat

Eric Chevet @ericchevet.bsky.social · 16/11/2024

go.bsky.app/HU7e761 @mattoolab.bsky.social done !!!!

103619

Reposted by Mike Kalwat

Matthew Freeman @mjafreeman.bsky.social · 12/11/2024

Waves of new BlueSky arrivals in last few days! I’ve been tracking starter packs relevant to molecular/mechanistic/genetic/cellular…etc biology Hope it’s helpful but warning: now a v long thread! Probably the last time I can do this...

15191113

Mike Kalwat @kalwat.bsky.social · 11/11/2024

go.bsky.app/3wdSpdi It can be difficult to recreate your following list here, please comment/tag any other islet/panc people I am missing and I will edit the pack.

6208