John Soghigian @jsoghigian.bsky.social · 08/05/2026Finally, we've provided additional analyses on codon position 3 and compositional heterogeneity ... The code we used is available at github.com/jsoghigian/m... ... We have files for alignments in the Culicitree github and subfolders (github.com/jsoghigian/c...). 010
John Soghigian @jsoghigian.bsky.social · 08/05/2026Pierce and colleagues were very collegial in discussions, and we appreciate their openness in discussing their results with us. Although we do not agree with their findings, we appreciate the enormous work that went into their manuscript. 120
John Soghigian @jsoghigian.bsky.social · 08/05/2026We do note that in this version of the letter, we were pressed for space; we originally were confined to a 500 word limit. We are considering where to go with our letter and possibly expand it, but we wanted to make sure the hard work of postdocs @genmorinaga.bsky.social and Huiqing Yeo was online. 110
John Soghigian @jsoghigian.bsky.social · 08/05/2026For codon position 3, when recoding purines and pyrimidines a R and Y (which resolves the compositional heterogeneity) or utilizing outgroups with higher GC content (thus addressing some heterogeneity), codon position 3 does indeed reflect two monophyletic subfamilies. 110
John Soghigian @jsoghigian.bsky.social · 08/05/2026Compositional heterogeneity in an alignment can violate assumptions of maximum likelihood inference, and we think this explains discrepancy between codon positions. Codon position 3 has strong evidence of GC content heterogeneity, moreso than either position 1 or 2. 120
John Soghigian @jsoghigian.bsky.social · 08/05/2026In our letter, we summarize the diverse evidence for two monophyletic subfamilies of mosquitoes - from other sequence data, to genomics, to morphology. This includes codon positions 1 and 2, and amino acids of the same genes; generally, only codon position 3 shows support for alternatives. 110
John Soghigian @jsoghigian.bsky.social · 08/05/2026Pierce et al., with results primarily from UCEs and third codon position, argue that Anopheles is sister to Culex, and that the classic view of two (extant) mosquito subfamilies is incorrect. They also find a much younger divergence time for mosquitoes than past studies. www.pnas.org/doi/10.1073/...pnas.orgPhylogenomics redefines the evolutionary history of mosquitoes | PNASMosquitoes have a substantial impact on human and animal health, but their deeper evolutionary relationships have been difficult to resolve. We inf... 110
John Soghigian @jsoghigian.bsky.social · 08/05/2026Colleagues and I address a recent phylogenetic & evolutionary hypothesis on mosquito evolution (from Pierce et al. 2025), namely that the two subfamilies of mosquitoes were not reciprocally monophyletic, and that Culex and Anopheles were sister to one another. We do not agree. 1115
Reposted by John SoghigianAndrea Gloria-Soria @agloriasoria.bsky.social · 24/04/2026First domestic #aegypti wild assemblies! (Not from your favorite lab colony). Led by @genmorinaga.bsky.social, a collaboration between @ctcaes.bsky.social @yale.edu and @jsoghigian.bsky.social. Two chromosome-scale genomes of wild Aedes aegypti aegypti… academic.oup.com/jhered/artic...academic.oup.comTwo chromosome-scale genomes of wild Aedes aegypti aegypti mosquitoes from North America and South-East AsiaAbstract. The yellow fever mosquito (Aedes aegypti) is the primary vector for diseases such as chikungunya, dengue fever, yellow fever, and Zika fever. The 043
Reposted by John Soghigian🧬Jacob L Steenwyk @jlsteenwyk.bsky.social · 12/11/2025Registration closes at the end of this week! bsky.app/profile/jlst... 022
John Soghigian @jsoghigian.bsky.social · 02/02/2025Also see the supplement of this paper for a discussion on Aedes... Long story short: Belkin recognized two sections that we find strong support for in genomic data. www.nature.com/articles/s41...nature.comPhylogenomics reveals the history of host use in mosquitoes - Nature CommunicationsDespite the significance of mosquitos for human health, little research has focused on their phylogeny. Here, the authors present a resolved phylogenetic history of mosquitoes based on phylogenomics s... 120
John Soghigian @jsoghigian.bsky.social · 02/02/2025As of Wilkerson et al 2015, most of us no longer use Ochlerotatus as a separate genus (but it is treated as a subgenus), as Don comments above. But, Aedes is not monophyletic and a growing consensus in the literature points to a few potentials, which could see the return of Ochlerotatus as a genus. 110
Reposted by John SoghigianAndrea Gloria-Soria @agloriasoria.bsky.social · 01/02/2025First genome assembly of wild #Aedes mosquitoes. Paper coming soon! Pre-print is out! Thanks to our collaboration with @jsoghigian.bsky.social, @ird-fr.bsky.social, @yale.edu and #CT_CAES. 0195
John Soghigian @jsoghigian.bsky.social · 03/12/2024Wow... This thread (and original plos post) are really interesting 071
Reposted by John SoghigianThe Onion @theonion.com · 28/11/2024"It’s us against the world now, turkey."theonion.com‘You’re The Bonnie To My Clyde,’ Says Biden Running Off With Pardoned TurkeyWASHINGTON—Participating in the annual tradition one last time before leaving office, President Joe Biden reportedly told a pardoned Thanksgiving turkey “You’re the Bonnie to my Clyde” on Monday befor... 566463497
Reposted by John SoghigianMaria Camila Ceballos @mariacceballos.bsky.social · 13/11/2024I’m happy to share a little bit of my story and “Jam” with this video from Arch Magazine from @ucalgary.bsky.social. See it here 👇🏼 archmagazine.ucalgary.ca/providing-a-...archmagazine.ucalgary.caProviding a Good Quality of Life is the Least We Can Do | arch magazineMaria Camila Ceballos knew she wanted to care for animals. She just didn’t know it would be in Canada and in the field of animal science. 261
John Soghigian @jsoghigian.bsky.social · 12/11/2024It's really good to see an alternative social media platform rapidly expand! Time to get back to checking here more often 🙂 190
Reposted by John SoghigianMark Cuban @mcuban.bsky.social · 12/11/2024Hello Less Hateful World 4679562223644
Reposted by John SoghigianRosemary Mosco @rosemarymosco.com · 11/03/2024Because folks liked my latest pigeon comic so much, here's another pigeon piece! I made this a couple years ago for a sadly now defunct publication called Pipe Wrench. I hope this piece helps spread more pigeon love. #pigeon #bird #comic #cartoon #science 🪶 191738625
Reposted by John SoghigianNicholas Bauer PhD @bioturbonick.net · 29/12/2023Hmm. The statistics in the first brain shrinking study seem screwy. Nonhospitalized (386) vs. Control (384) was not even close to significant, but all cases (401) vs control was just barely significant? Sorry, I don't buy this result as meaningful. www.nature.com/articles/s41... 5474
John Soghigian @jsoghigian.bsky.social · 29/11/2023A case of measles in Calgary 😨 www.albertahealthservices.ca/news/Page178...albertahealthservices.caConfirmed case of measles prompts public alert to potential exposures | Alberta Health ServicesCALGARY– Alberta Health Services (AHS) has confirmed that an individual with lab-confirmed measles has been in public settings in Calgary while infectious. 011
Reposted by John SoghigianJason Moore @moorejh.bsky.social · 09/11/2023#academia I recall getting a handwritten note from my VD for Research when I got my first NIH R01 funded. A very nice gesture. We need more of this! 021
John Soghigian @jsoghigian.bsky.social · 04/11/2023Join us for an excellent symposium on some of the "other sides" of vector biology research! 020
Reposted by John SoghigianDon Yee @mosquitolab.bsky.social · 02/11/2023Attending @entsocamerica.bsky.social meeting? Join @jsoghigian.bsky.social and myself for our symposium, Beyond the Bite: Natural History, Systematics, and Ecology Enhance Knowledge of Our Most Deadly Foe, cdmcd.co/B8PqPW #EntSoc23 041
John Soghigian @jsoghigian.bsky.social · 31/10/2023Thanks Don! Wouldn't have been possible without the hard work of @genmorinaga.bsky.social 010
Reposted by John SoghigianDon Yee @mosquitolab.bsky.social · 30/10/2023Known of this work for a while now so really happy to see it out in print. Work by @jsoghigian.bsky.social and others, Phylogenomics reveals the history of host use in mosquitoes www.nature.com/articles/s41... 143
Reposted by John SoghigianAlisa Bokulich @alisabokulich.bsky.social · 29/08/2023A Bluesky quick primer 🧵 for recent arrivals: 1. check default settings -- they set to min threshold likes before see in feed-- can change to show all. 29665406
Reposted by John SoghigianTwisteddoodles @twisteddoodles.bsky.social · 26/10/2023The ghostest with the mostest 172064633
Reposted by John SoghigianSkype a Scientist @skypeascientist.bsky.social · 24/10/2023We serve classrooms with connections to scientists for free. We put science into people's lives with public art & pop-ups. We help scientists connect with their creativity to communicate science. We rely on YOU to do this work. Monthly support keeps us alive ❤️ www.patreon.com/SkypeAScient...patreon.comSkype a Scientist | PatreonConnecting people with science through conversations & art 19081
Reposted by John SoghigianYashar Ali 🐘 @yasharali.bsky.social · 17/10/2023Get your Kleenex out. A group of Chicago area Rabbis attended the funeral of Wadea Al-Fayoume, the six year old Palestinian-American boy who was brutally murdered by his landlord due to his ethnicity and religion. Rabbi Ari Hart explains why the Rabbis attended the funeral in the screenshot below. 6965300
Reposted by John SoghigianJohn Gilleard @johngilleard.bsky.social · 16/10/2023Hi Bluesky community My first post here after years on Twitter. Interests include all things science & Higher Ed. In particular Parasitology, drug resistance, molecular epidemiology/diagnostics, genetics/genomics genomics and veterinary medicine. Thanks for the invite @jsoghigian.bsky.social ! 1112
Reposted by John SoghigianBluesky @bsky.app · 13/10/2023Just published on our blog: Bluesky for Journalists FAQ This page also includes a link to a waitlist form for journalists, so members of the press no longer have to email our press inbox for a code. We appreciate everyone's help sharing this information!blueskyweb.xyzBluesky for Journalists 7430202498
Reposted by John SoghigianAmy J. Rutenberg @amyjay401.bsky.social · 14/10/2023(Pls repost) Folks who majored in history, english, or something else “useless,”what was your first job out of school? What are you doing now? I know there are plenty of online resources about jobs but I’m trying to show my students that careers are often not straight lines.Thank you!!!! 19815888
Reposted by John SoghigianRosemary Mosco @rosemarymosco.com · 12/10/2023Some halloween costume ideas. 🪶🧪 11568169
Reposted by John SoghigianJason Rasgon @vectorgen.bsky.social · 09/10/2023Come be our colleagaue! Assistant/Associate Professor in Vector Biology/Ecology! Specific topic area open! psu.wd1.myworkdayjobs.com/en-US/PSU_Ac...psu.wd1.myworkdayjobs.comAssistant/Associate Professor of Arthropod Vector Biology and/or EcologyAPPLICATION INSTRUCTIONS: CURRENT PENN STATE EMPLOYEE (faculty, staff, technical service, or student), please login to Workday to complete the internal application process. Please do not apply here, a... 02236
Reposted by John SoghigianDr. Stephanie @punkrockscience.bsky.social · 09/10/2023Man who routinely gets ratioed attempts to kill the entire idea of being ratioed.forbes.comAfter Deleting Twitter/X Headlines, Elon Musk Will Hide Reply, Retweet And Like NumbersThis past week, Musk followed through on a promise to delete embedded headlines and lede copy from posted article links. 04211
Reposted by John SoghigianDani cRabaiotti 🦀 @danirabaiotti.bsky.social · 09/10/2023Is science bluesky fully realised yet? Do we have a discourse about this absolutely bananas paper? 🧪 www.nature.com/articles/s41...nature.comAssembly theory explains and quantifies selection and evolution - NatureAssembly theory conceptualizes objects as entities defined by their possible formation histories, allowing a unified language for describing selection, evolution and the generation of novelty. 3211918
John Soghigian @jsoghigian.bsky.social · 07/10/2023Exciting for this to finally be online! Was a privilege to be part of such a great international team. Excellent phylogenetic comparative work by @genmorinaga.bsky.social to cap it all off! 063
Reposted by John SoghigianNicholas Mancuso @nmancuso.bsky.social · 03/10/2023👋 Hi genetics/statgen/gen-epi trainees! 🧬 🧪 If you are interested in reviewing please let me know! We (HGG Advances, eLife) are constantly in need of knowledgeable reviewers and would be more than happy to work with you. Please feel free to email me (or other editors) if you're interested! 02321
Reposted by John SoghigianJack Maynard(he/him) @jhmsparky.bsky.social · 05/10/2023Pete, the Townsend's Warbler back again. ( I like to think this is the same guy who visits every year around now). Just so happy we didn't miss him as we fly east tomorrow. #birding 0373
John Soghigian @jsoghigian.bsky.social · 05/10/2023I have both active, as a lot of my non science follows do not use Bluesky yet. But I spend more time on here, since most of my science / professional interests and friends have migrated 010
Reposted by John SoghigianSurprised Eel Historian, PhD @greenleejw.bsky.social · 05/10/2023It's Thursday. You need some eels in your life, right? And some otters? Here you go! A scene of otters & eels, from an early 15th C. copy of Gaston Phoebus's Livre de la chasse. Eel blood is toxic to mammals, but otters don't care. They love them some eels. Can you blame them? 🧪🗃️ 410824
Reposted by John SoghigianRebekah Rogers @evolscientist.bsky.social · 05/10/2023In need of a new postdoc for our work on evolution of genetic novelty. Multiple datasets in hand for Drosophila and other organisms. Email for more detail before applying. jobs.charlotte.edu/postings/52545jobs.charlotte.eduPostdoctoral Fellow - BioinformaticsThe employee will report to Professor Rebekah L. Rogers and will be a senior member of Professor Rogers’s research group, supporting projects through original research, collaboration with other team... 11625
Reposted by John SoghigianRosemary Mosco @rosemarymosco.com · 04/10/2023It's mushroom season! Here are all the types you will see. My mailing list: buttondown.email/rosemarymosco 24897352
Reposted by John SoghigianRead the book Read Raising Expectations (and Raising Hell) @jphillll.bsky.social · 04/10/2023Bad working conditions for nurses literally mean bad patient care. Endless solidarity for every health care worker striking for better. 4579149
Reposted by John SoghigianFrontRangeWildflowers @frwildflowers.bsky.social · 04/10/2023Blue sky over blue lupine and arrowleaf balsamroot above the Blue River🌿 1398
Reposted by John SoghigianAnne Fausto-Sterling @birdlady.bsky.social · 04/10/2023How about a Lava heron and sally lightfoot crab from the Galapagos for a bedtime photo (i.e. bedtime on the east coast of the US). #birds #evolbiol #ecoevo 2455