Reposted by Jim MansfieldChristophe 🔬 Leterrier @christlet.bsky.social · 15/10/2026New from Peng Yin's lab: multiplexed labeling in thick tissues (16-plex in a 1-mm brain slice here 😎) using DNA amplification by cyclic extension www.biorxiv.org/content/10.6... 1256 25
Reposted by Jim MansfieldTimothy Snyder @timothysnyder.bsky.social · 15/10/2026No amount of support for Russia can end the war, because Russia is the criminal aggressor. A modicum of support for Ukraine could, however, end the war, by making it impossible for Russia to continue. This should not be a hard choice. 472667955 2.7K
Reposted by Jim MansfieldNoam Ross @noamross.net · 13/10/2026Comments the NIH proposal to screw up peer review are due TODAY. If you need a hand figuring out how to submit a comment or what to write, see Josh's post below. 🧪 02323 23
Reposted by Jim MansfieldInternational Society for Advancement of Cytometry @isacytometry.bsky.social · 13/10/2026Have You Applied Yet? There’s still time to submit your application for ISAC SRL Recognition. 📅 Deadline: November 15 Take the next step in validating your lab’s excellence. isac-net.org/srl-rec-prog/isac-net.orgShared Resource Laboratory - ISAC: International Society for Advancement of Cytometry 011 1
Reposted by Jim MansfieldAACR Journals @aacrjournals.bsky.social · 13/10/2026From the October issue of Cancer Immunology Research: Periductal Fibroblast Density Defines Lymphocyte Exclusion via a CD44-Dependent Stromal Checkpoint in Pancreatic Cancer buff.ly/a2KzimQ 011 1
Reposted by Jim MansfieldAlex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 11/10/2026"Ukraine, if you're listening…" 0152 15
Reposted by Jim MansfieldJoshua Weitz @joshuasweitz.bsky.social · 11/10/2026Lots of options here & you *should* write in with your comment. Here's another piece that might resonate with you (and which I've written about extensively here). Take care.joshuasweitz.substack.comAn Emperor of All Malice: On White House Efforts to Seize Control of NIH FundingUnilateral efforts by the administration to politicize funding decisions jeopardize discovery, health, and the economy… and demand a timely, effective response. 031 3
Reposted by Jim MansfieldItai Yanai @itaiyanai.bsky.social · 12/10/2026Postdoc opening: My lab at NYU Langone Health is looking for a new postdoctoral fellow with wet-lab experience for an exciting project. 22522 25
Reposted by Jim MansfieldCeleste Ng @pronounced-ing.bsky.social · 11/10/2026"Whereas the AI users got answers wrong or gave up entirely when the AI assistance was withdrawn, the group without AI stuck with the task and were more successful at the end." 3337118 337
Reposted by Jim MansfieldMark Histed @markhisted.org · 10/10/2026Correct. Vought and Bhattacharya want to do to NIH what they have gotten further with at NSF- turn it into a slush fund for their political preferences. But peer review is popular, and it is required by law. So they are slowly chipping away at peer review process in an effort to break it. 38546 85
Reposted by Jim MansfieldKarl Schiller @kcschiller.bsky.social · 10/10/2026They are already doing it at the USDA. My last review had no scores, but lots of "No improvement needed". 033 3
Reposted by Jim MansfieldAlicia Izquierdo @aliciaizquierdo.bsky.social · 10/10/2026Can we also have a series of articles on the limitations of organoids? Or have I missed them? 2356 35
Reposted by Jim MansfieldAlex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 11/10/2026People who recklessly endanger their kids should not be allowed to do so. 0132 13
Reposted by Jim MansfieldChris Ashwood @cashwood.proteaglyco.com · 11/10/2026A discussion about the recent AI-based math proof flood. One aspect resonates - research themes improve impact. One sentiment I’m not reading much about is that if the capital spent on this effort was allocated to human researchers instead. Surely better ROI. proofsandprompts.com/2026/10/08/1...proofsandprompts.com100+ reactions to 100+ solutions“Many of us are grappling with OpenAI’s announcement on 6 October. We feel that it is useful to have an updating snapshot of the community’s gut feeling.” 011 1
Reposted by Jim MansfieldRita Strack @ritastrack.bsky.social · 10/10/2026I was confident this would be the outcome following an investigation. Contest-Winning Microscope Video Thrown Out for Using Generative AI share.google/3CrmkbqH0kHT...share.googleContest-Winning Microscope Video Thrown Out for Using Generative AINing Xu's winning entry to Nikon Instruments' Small World in Motion competition was ineligible due to AI, a spokesperson for the contest told Gizmodo. 1448 44
Reposted by Jim MansfieldAlex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 21/08/2026"Structural inequalities in segregation, economic conditions, and educational access emerge as key pathways linking historical slavery to contemporary mortality disparities…"pnas.orgHistorical slavery predicts contemporary disparities in mortality between Black and White Americans | PNASWe tested whether contemporary Black–White mortality disparities in the United States may be rooted in the historical legacy of slavery and perpetu... 1104 10
Reposted by Jim MansfieldProf Gavin Yamey MD MPH @gavinyamey.bsky.social · 22/08/2026Oh God almighty, the horror show continues; you can see why RFK Jr and Bhattacharya want him These “treatments” are utterly barbaric 0205 20
Reposted by Jim MansfieldHELL Kennedy @helenkennedy.com · 21/08/2026The Trump administration fired the editor of Stars & Stripes. The military newspaper's publisher, who announced he would retire earlier this week, was also fired. The paper had revealed the deplorable conditions on the USS Lincoln, embarrassing Hegseth and Trump. 241508650 1.5K
Reposted by Jim MansfieldBill Stewart @billstewart.bsky.social · 19/08/2026It's amazing how many people simultaneously believed that Covid was a nothingburger cold gone by Easter and you should patriotically get it over with so the bars can reopen, and also that Covid was Fauci's Chinese Bioweapons Lab Leak Designed To Kill Us All. I mean, pick one or the other. 2247 24
Reposted by Jim MansfieldEric Topol @erictopol.bsky.social · 18/08/2026The dangers of RFK Jr's peptide push Example: "If you have a few precancerous cells lurking indolently in your prostate or breast, injecting a peptide that stimulates human growth hormone might supercharge them into a tumor." gift link wapo.st/4wycy3O 13227118 227
Jim Mansfield @jrmansfield.bsky.social · 18/08/2026Say hello to Elizabeth Hillman for me! We missed each other the last time I was there. 011 1
Reposted by Jim MansfieldSanho Tree @sanho.bsky.social · 18/08/2026“X’s algorithm learns what you hate and shows you more of it, according to a new study just published in the Proceedings of the National Academy of Sciences (PNAS)…It also showed that X serves more ragebait to people who say they are Democrats, although the exact reason for that is unclear.” 04723 47
Reposted by Jim MansfieldEric Topol @erictopol.bsky.social · 18/08/2026Enough of the cure talk. Where are the cures for these diseases? 1928044 280
Reposted by Jim MansfieldInternational Society for Advancement of Cytometry @isacytometry.bsky.social · 13/08/2026We're excited to begin the journey toward another unforgettable CYTO experience filled with groundbreaking science, global collaboration, and innovative discoveries. And to kick things off, we're thrilled to announce the CYTO 2027 Program Chairs! Raluca Niesner, PhD Sara De Biasi, PhD 111 1
Reposted by Jim MansfieldDon Moynihan @donmoyn.bsky.social · 06/08/2026Is this just business as usual in politics? No. Approval rates of federal disaster aid requests were about the same regardless of the state and did not vary much with the party of the President. This graph powerfully conveys the scale of the partisan discrimination now. 231485546 1.5K
Reposted by Jim MansfieldAlex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 13/08/2026Ingest your own BS, DoJ: 071 7
Reposted by Jim MansfieldEric Topol @erictopol.bsky.social · 12/08/2026By the WSJ editorial board www.wsj.com/opinion/dona... 35617 56
Reposted by Jim MansfieldKeri Martinowich @martinowk.bsky.social · 12/08/2026With expansion of several stem cell based initiatives @lieberinstitute.bsky.social - we are hiring! We are looking for a Staff Scientist with expertise in hiPSCs and iPSC-derived neuronal models to join our Stem Cell Core, directed by @tsawada1.bsky.social recruiting.paylocity.com/recruiting/j... 11917 19
Reposted by Jim MansfieldEMBL Events @events.embl.org · 11/08/2026You only have until 11 Sep to submit your abstract for #EMBOomics! ➡️ s.embl.org/omx26-01-bl Join us to discuss the latest developments in the field with leaders in genomics, dynamic proteomics, quantitative imaging, and synthetic biology. 053 5
Jim Mansfield @jrmansfield.bsky.social · 09/08/2026First peer-reviewed paper combining Imaging Mass Cytometry with Xenium on the same FFPE section. Found EMT & checkpoint signatures invisible at the transcript level. Congrats @ankuroncofetal.bsky.social @standardbiotools.bsky.social et al! doi.org/10.1158/2767... #SpatialBiology #IMCdoi.orgAn Integrated Spatial Multi-Omics Workflow for Sequential RNA and Protein Profiling in FFPE Tumor TissueAbstract. Understanding complex cellular niches, such as tertiary lymphoid structures (TLS), requires spatially resolved, multi-omic approaches that link transcriptional states and protein expression ... 030 3
Reposted by Jim MansfieldNJBIZ @njbiz.bsky.social · 31/07/2026In case you missed it: Michael Johnson steps down as NJII president to lead Multiplex Bio, acquiring Standard BioTools' mass cytometry business in a deal valued up to $10 million. 111 1
Reposted by Jim MansfieldGreg Folkers @gregfolkers.bsky.social · 04/08/2026Nature: Controversial White House plan to overhaul US science funding faces Senate opposition by Dan Garisto @nature.com @dangaristo.bsky.social go.nature.com/3TWoXRw 0187 18
Reposted by Jim MansfieldDan Froomkin/Press Watch/Heads Up News @froomkin.bsky.social · 31/07/2026This is a completely insane interview in that the things they are discussing are so alarming that their heads should be exploding and yet they are calm. History will be unkind to those, like the NYT, who underreacted to Trump’s violation of the country. 1/2 www.nytimes.com/2026/07/31/o...nytimes.comOpinion | How Trump Has Changed, With Maggie HabermanThe New York Times correspondent says 70 percent of the president’s mind is dedicated to White House renovations. 771205273 1.2K
Reposted by Jim MansfieldEric Topol @erictopol.bsky.social · 30/07/2026Inflammation is a driver of age-related diseases (inflammaging) and this new NYT magazine article gets deep into the progress that is being made to track and block it gift link www.nytimes.com/interactive/...nytimes.comInflammation Keeps Us Alive. It's Also Making Us Sick. (Gift Article)The discovery that chronic inflammation is a cause of myriad illnesses could be this century's biggest medical breakthrough. 723471 234
Reposted by Jim Mansfieldderek guy @dieworkwear.bsky.social · 29/07/2026Despite all the accusations of crimes and cover-ups, the Trump admin has never actually prosecuted or jailed anyone. The supposed stolen 2020 election, Jan 6 deep state, Dr Fauci, etc. All of its is just theater for the base, revving them up. In the end, will undermine faith in gov and institutions. 1004451742 4.5K
Reposted by Jim MansfieldBeth Cimini 🔬💻📊 @bethcimini.bsky.social · 30/07/2026Had a super lovely time on this podcast talking about bioimage analysis -the practice, the career, and the ~*~magic~*~ of it all. Check it out below!bioinformaticscro.comBeth Cimini - The Bioinformatics CRO PodcastBeth Cimini, of the Cimini Lab at the Broad Institute, discusses her work at the intersection of microscopy, computational biology, and open source software. 092 9
Reposted by Jim MansfieldPeter Jacobs @pjacobs.bsky.social · 30/07/2026Said this before, and will keep saying it: Prior to vaccine availability in the US, almost 1 in 5 people hospitalized during the pandemic DIED. For those admitted to an ICU it was more like 40-50%. The vaccines, and then the combination of vaccines and less lethal variants, changed everything. 37235 72
Reposted by Jim MansfieldJon B. Wolfsthal @jonatomic.bsky.social · 29/07/2026History will praise Fauci as a leader and will bunch his accusers with McCarthy and J Edgar Hoover. They praise themselves at the cost of good men and women who know and care and seek to help our country. They have no decency, at long last. 1277 27
Reposted by Jim MansfieldOlúfẹ́mi O. Táíwò @olufemiotaiwo.bsky.social · 29/07/2026to keep functioning, a society must discourage baldfaced lying, especially by authorities 902399409 2.4K
Reposted by Jim MansfieldEleanor Courtemanche @ecourtem.bsky.social · 29/07/2026This is why they’re going after Dr Fauci: he impeded grifters 18658231530 5.8K
Reposted by Jim MansfieldScience Magazine @science.org · 23/07/2026A new special issue, with papers in Science and #ScienceAdvances, features single-cell and multiomic studies from the National Institutes of Health Common Fund's 4D Nucleome Program, which examines a fourth dimension of nuclear organization. Learn more: scim.ag/4wc4SF8 0507 50
Reposted by Jim MansfieldAlex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 27/07/2026"Many publicly traded companies are putting out announcements about their AI productivity gains when I know for a fact that the businesses have done nothing other than purchase Copilot licenses and declare victory."ludic.mataroa.blogAI Mania Is Eviscerating Global Decision-Making — Ludicity 1295 29
Reposted by Jim MansfieldGreg Egan @gregegansf.bsky.social · 27/07/2026While the Fields Medal celebrates the under-40s, the mathematician Joan Birman has, at the age of 99, solved a major open problem in representations of the Braid groups, a topic she has worked on for more than 60 years. 121298320 1.3K
Reposted by Jim MansfieldJenna Norton @jenna-m-norton.bsky.social · 24/07/2026NIH is testing their ability to terminate “unaligned” grants, with at least one new termination documented. Disgustingly, they awarded this grant simply so they could add a termination clause. Then they terminated it. From @jocelynkaiser.bsky.social www.science.org/content/arti...science.orgNIH is again terminating grants that the Trump administration dislikesWith cancellation of health disparities project, agency may be testing new way to legally kill politically sensitive grants 46938 69
Reposted by Jim MansfieldPaul Bleicher @pbleic.bsky.social · 24/07/2026Astonishing. RFK Jr. adds 8 members to a 6 member FDA advisory panel. 6 of them were sellers of peptides, and the 7th a compounding pharmacist. In an 8-6 vote with all 8 votes coming from these new panel members, the panel approved 4 peptides against the objections of FDA scientists.nytimes.comFDA Panel Supports Lifting Restrictions on Four Peptides (Gift Article)In an all-day hearing, the agency’s scientists argued against allowing broad access to unproven drugs that the agency had banned three years ago. 16428271506 2.8K
Reposted by Jim MansfieldMike Masnick @masnick.com · 25/07/2026Wait. They all shake hands at the end? What are we even doing here? He's the US President suing you for $20 billion for reporting on the birthday card he sent his friend the pedophile in which he drew a naked girl & mused about secrets. And they all shake hands? 834397986 4.4K
Reposted by Jim MansfieldAlex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 25/07/2026This is their overt goal. They are not pretending otherwise. 0247 24
Reposted by Jim MansfieldAaron Sojourner @aaronsojourner.org · 25/07/2026Admirable clarity @science.org 4974902710 7.5K
Reposted by Jim MansfieldNikolai Slavov @slavov-n.bsky.social · 18/07/2026Communicating research results is among the most important aspects of science; it can be tremendously rewarding and gratifying. Yet, it often falls short. This is an insightful & humorous take on giving a talk by @itaiyanai.bsky.social. 1/ 1113 11