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Quinn Lee

@jquinnlee.bsky.social
736 followers 322 following 28 posts

Navigation & memory researcher CIHR Postdoctoral Fellow @ McGill University Incoming Assistant Professor @ University of Alberta (starting July 2025) Accepting graduate student applications to start Fall 2025: sites.psych.ualberta.ca/NMSLab

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Reposted by Quinn Lee
Ciaran Murphy-Royal @murphyroyallab.org · 22/08/2025
🚨Another PI job opening in the Neuroscience dept. at @umontreal.ca ! 🚨 www.nature.com/naturecareer...
nature.com
Professor at the rank of Assistant or Associate Professor, in the field of neurocircuitry - Montréal, Quebec (CA) job with Université de Montréal | 12843808
Professor at the rank of Assistant or Associate Professor, in the field of neurocircuitry involved in the production of complex behaviors
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Alexandra Keinath @atkeinath.bsky.social · 15/07/2025
Trans rights are human rights. Fresh work incoming: Here we quantitatively compare the representational geometry of mouse CA1 and human spatial memory during environmental deformations. Briefest TLDR: Human memory looks like a change-resistant version of mouse CA1. www.biorxiv.org/cgi/content/...
biorxiv.org
Change-resistance distinguishes the representational geometries of human spatial memory and mouse CA1 in deformed environments
Prior work has highlighted qualitative similarities between the neural instantiations of cognitive maps in rodents and memory-guided navigation in humans, suggesting a conservation of representational...
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Dan Levenstein @dlevenstein.bsky.social · 23/06/2025
Thrilled to announce I'll be starting my own neuro-theory lab, as an Assistant Professor at @yaleneuro.bsky.social @wutsaiyale.bsky.social this Fall! My group will study offline learning in the sleeping brain: how neural activity self-organizes during sleep and the computations it performs. 🧵
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Kadjita Asumbisa @kasumbisa.bsky.social · 15/04/2025
Excited to share the sequel to our 2022 paper! In this follow-up, we show that the stable head direction (HD) signals we reported in blind mice rely on stereo olfaction—that is, the comparison of odor info. between the two nostrils. Link: www.nature.com/articles/s41... 🧵highlights below
nature.com
Stereo olfaction underlies stable coding of head direction in blind mice - Nature Communications
Stereo olfaction involves comparing odor differences between the two nostrils. Here, using neuronal recordings and a behavioral test, the authors demonstrate that blind mice use stereo olfaction to fo...
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Blake Richards @tyrellturing.bsky.social · 08/04/2025
BTSP, but not STDP, can account for place field changes in hippocampus, out in Nature Neuroscience today: www.nature.com/articles/s41... 🧠📈 🧪
nature.com
Synaptic plasticity rules driving representational shifting in the hippocampus - Nature Neuroscience
Madar et al. report that behavioral timescale synaptic plasticity (BTSP), not spike-timing-dependent plasticity, explains heterogeneous place fields shifting in the hippocampus. The probability of BTS...
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Quinn Lee @jquinnlee.bsky.social · 08/04/2025
The dataset and code for our recent paper in Neuron (tinyurl.com/yc48d6vr) is online now! The data is available on Zenodo (zenodo.org/records/1486...) and code on Github (github.com/jquinnlee/ge...). Big thanks to @markbrandonlab.bsky.social and @atkeinath.bsky.social on this effort! #neuroskyence 🧠
zenodo.org
Mouse CA1 Calcium Imaging and Behavioural Dataset in 3x3 Geometric Morph Paradigm
The following dataset was collected by Dr. J. Quinn Lee, Dr. Alexandra T. Keinath, and Erica Cianfarano in the laboratory of Dr. Mark P. Brandon. All methods and details are described in the original ...
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Reposted by Quinn Lee
COSYNE @cosynemeeting.bsky.social · 26/03/2025
Looking forward to seeing you all in Montreal this week 🧠🧠🧠 Use #cosyne2025 so we can 👀 what you're up to!!
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Sarthak Chandra @sarthakc.bsky.social · 19/02/2025
1/ Our paper appeared in @Nature today! www.nature.com/articles/s41... w/ Fiete Lab and @khonamikail.bsky.social . Explains emergence of multiple grid cell modules, w/ excellent match to data! Novel mechanism for applying across vast systems from development to ecosystems. 🧵👇
nature.com
Global modules robustly emerge from local interactions and smooth gradients - Nature
The principle of peak selection is described, by which local interactions and smooth gradients drive self-organization of discrete global modules.
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Blake Richards @tyrellturing.bsky.social · 12/02/2025
Position open for Director of Research Innovation & Operations at Concordia as part of the Abundant Intelligences (www.indigenous-ai.net/abundant/) project, which seeks to reshape AI with indigenous insights: www.kbrs.ca/Career/17387... Please share!!! 🧪 #MLSky
kbrs.ca
Director of Research Innovation & Operations (DRIO) – Abundant Intelligences
Application deadline: March 21, 2025
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Kim Stachenfeld, PhD @neurokim.bsky.social · 11/02/2025
Very pleased to share our recent work, in which we use LLMs for automated discovery of interpretable models of animal behavior 🪰🐀🕵️‍♀️ that take the form of Python programs 🐍 See below for a summary of key results by @pcastr.bsky.social!
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Matteo Carandini @carandinilab.net · 02/02/2025
It's finally out! Visual experience orthogonalizes visual cortical responses Training in a visual task changes V1 tuning curves in odd ways. This effect is explained by a simple convex transformation. It orthogonalizes the population, making it easier to decode. 10.1016/j.celrep.2025.115235
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Carl Zimmer @carlzimmer.com · 28/01/2025
American science and medicine has been thrown into chaos and uncertainty over the past week. Here are some stories to get up to speed. 1/12
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The Transmitter @thetransmitter.bsky.social · 10/01/2025
Eleanor Maguire, who died 4 January at age 54, pioneered the famous London taxi-driver study and naturalistic approaches for studying spatial and episodic memory in people. By @callimcflurry.bsky.social www.thetransmitter.org/memory/remem...
thetransmitter.org
Remembering Eleanor Maguire, ‘trailblazer’ of human memory
Maguire, mastermind of the famous London taxi-driver study, broadened the field and championed the importance of spatial representations in memory.
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Surya Ganguli @suryaganguli.bsky.social · 06/12/2024
Stellar new work lead by the inimitable James Whittington in Neuron that develops a new theory unifying episodic and working memory and explains diverse hippocampal and prefrontal data: www.cell.com/neuron/fullt... w/Will Dorrell, @behrenstimb.bsky.social Mohamedy El Gaby
cell.com
A tale of two algorithms: Structured slots explain prefrontal sequence memory and are unified with hippocampal cognitive maps
The algorithm of the prefrontal working memory system on sequence memory tasks is not well understood, whereas it is well understood for the hippocampal episodic memory system. This work shows a mathematical duality between working and episodic sequence memory. This leads to a computational understanding of sequence working memory—as structured activity slots. This theory algorithmically explains recurrent neural network (RNN) and prefrontal representations during sequence memory tasks.
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Quinn Lee @jquinnlee.bsky.social · 02/12/2024
New brief report now out in Hippocampus! We used functional molecular imaging to ask if activity sparsity in the hippocampus (dorsal to ventral DG, CA3 and CA1) depends on memory task performed. Turns out the pattern is identical across tasks! onlinelibrary.wiley.com/doi/10.1002/... #NeuroSky 🧠🧪
onlinelibrary.wiley.com
Sparsity of Population Activity in the Hippocampus Is Task‐Invariant Across the Trisynaptic Circuit and Dorsoventral Axis
Evidence from neurophysiological and genetic studies demonstrates that activity sparsity—the proportion of neurons that are active at a given time in a population—systematically varies across the can...
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Reposted by Quinn Lee
Caswell Barry @caswell.bsky.social · 26/11/2024
Our latest preprint has landed www.biorxiv.org/content/10.1... Fantastic work from @laurenb29.bsky.social and Will de Cothi showing how many of the cell types associated with subiculum (e.g. boundary vector cells, corner cells) can be understood as successor features. TLDR: SUB not CA1 is the SR
biorxiv.org
Unifying Subicular Function: A Predictive Map Approach
The successor representation has emerged as a powerful model for understanding mammalian navigation and memory; explaining the spatial coding properties of hippocampal place cells and entorhinal grid ...
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Quinn Lee @jquinnlee.bsky.social · 29/11/2024
Wicked new pre-print from @atkeinath.bsky.social More evidence for a unifying predictive framework of cognitive mapping in the mouse brain! Also first time I have seen reliable between subject differences in maps over protracted time. Nicely done!!
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Marlos C. Machado @marloscmachado.bsky.social · 27/11/2024
The Dept. of Computing Science at the University of Alberta is hiring! The new hires in AI will be nominated for a Canada CIFAR AI Chair. We have 3 TT positions: AI/ML/DL Theory: apps.ualberta.ca/careers/post... AI + SWE: apps.ualberta.ca/careers/post... Systems: apps.ualberta.ca/careers/post...
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Reposted by Quinn Lee
Tom George @tomnotgeorge.bsky.social · 25/11/2024
What are the brain’s “real” tuning curves? Our new preprint "SIMPL: Scalable and hassle-free optimisation of neural representations from behaviour” argues that existing techniques for latent variable discovery are lacking. We suggest a much simpl-er way to do things. 1/21🧵
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Nima Dehghani @neurovium.bsky.social · 26/11/2024
How can biology teach us to design better AI?🤔 Our new paper, w Mike @drmichaellevin.bsky.social "Bio-inspired AI: Integrating Biological Complexity," explores how biological principles like adaptability, context-dependence, and hierarchical processing can inspire the next generation of AI. 🧵👇1/n
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Tony Zador @tonyzador.bsky.social · 21/11/2024
Want to be part of the NeuroAI community CSHL ? Applications are open for outstanding graduate students in Artificial Intelligence to spend the summer at CSHL as NeuroAI Interns. Deadline: Dec 10th, 2024. Please spread the word! www.schooljobs.com/careers/cshl... @cshlaboratory.bsky.social
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Quinn Lee @jquinnlee.bsky.social · 22/11/2024
Psyched that my postdoc work w @markbrandonlab.bsky.social + @atkeinath.bsky.social is now in Neuron! TL/DR: remapping in CA1 has a representational structure that is reliable across brains, and we use this representation to test models of cognitive maps. #NeuroSky #NeuroAI 🧪🧠 tinyurl.com/4juhmad8
tinyurl.com
Identifying representational structure in CA1 to benchmark theoretical models of cognitive mapping
Decades of theoretical and empirical work have suggested the hippocampus instantiates some form of a cognitive map. Yet, tests of competing theories h…
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Reposted by Quinn Lee
Andrew MacAskill @macaskillaf.bsky.social · 22/11/2024
Huge congrats to @karyna-mi.bsky.social for her paper published today in Science! She found that the hippocampus is really important for a key strategy we use to make decisions called hidden state inference! 🧪 🧠https://www.science.org/doi/10.1126/science.adq5874 1/7
science.org
Hidden state inference requires abstract contextual representations in the ventral hippocampus
The ability to use subjective, latent contextual representations to influence decision-making is crucial for everyday life. The hippocampus is hypothesized to bind together otherwise abstract combinat...
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Surya Ganguli @suryaganguli.bsky.social · 21/11/2024
Our new paper in @natureportfolio.bsky.social shows entorhinal grid cells adapt their representations to a new environment in one-shot and derives a model that fuses landmarks & motion to *predict* the detailed grid rep *before* the mouse enters the new environment! www.nature.com/articles/s41...
nature.com
One-shot entorhinal maps enable flexible navigation in novel environments - Nature
How the navigational system of the brain constructs spatial maps that require both rapid changes and representational accuracy is explored.
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Blake Richards @tyrellturing.bsky.social · 11/11/2024
Registration for #COSYNE2025 is now open! www.cosyne.org/registration #neuroscience #NeuroAI
cosyne.org
Registration — COSYNE
Registration is open for Computational and Systems Neuroscience (COSYNE) 2025 - 27 March - 1 April. Register early to reserve your place and to ensure you get the best rate.
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Paul Masset @paulmasset.bsky.social · 09/11/2024
I am recruiting graduate students for my lab @mcgillu.bsky.social for admission in Fall 2025! Get in touch if you're interested in how brain circuits implement distributed computation, including dopamine-based distributed RL and probabilistic representations.
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Jason Shepherd @jasonsynaptic.bsky.social · 14/10/2024
I am and have been fascinated with how memories are formed and stored. A big challenge, not unique to memory, is synthesizing concepts across scales of anaylsis - from molecules to computation. Here I try to distill how we can move forward in understanding memories. Thanks to all the contributors!
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Quinn Lee @jquinnlee.bsky.social · 07/10/2024
One more time!! Presenting my final postdoc project with @markbrandonlab at U29 from 8–12 this morning! Come say hi!! #SfN24
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Quinn Lee @jquinnlee.bsky.social · 25/09/2024
I am thrilled to share that I have accepted a position as Assistant Professor at the University of Alberta in the Department of Psychology to start next summer, and will be accepting graduate student applications (due December 1st)! @Psych_UAlberta sites.psych.ualberta.ca/NMSLab/
sites.psych.ualberta.ca
NMS Lab
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Quinn Lee @jquinnlee.bsky.social · 18/09/2024
New short but sweet paper on a topic I love - sparse representation in the hippocampus! Using functional molecular imaging, we found that activity sparsity is highly conserved across memory tasks. Feedback is welcome! www.biorxiv.org/content/10.1...
biorxiv.org
Sparsity of population activity in the hippocampus is task-invariant across the trisynaptic circuit and dorsoventral axis
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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Quinn Lee @jquinnlee.bsky.social · 16/09/2024
uleth.peopleadmin.ca/postings/7749
uleth.peopleadmin.ca
Tier 2 Canada Research Chair (CRC) in Machine Learning and Artificial Intelligence
About the PositionThe Faculty of Arts and Science at the University of Lethbridge invites applications for the position of Tier 2 Canada Research Chair (CRC) in Machine Learning and Artificial Intelli...
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Quinn Lee @jquinnlee.bsky.social · 16/09/2024
Pleased to share some major updates on my post-doc work w Mark Brandon, Alexandra Keinath, and Erica Cianfarano. TL/DR - We show: 1) cognitive remapping in HPC is very reliable across animals; 2) We directly test models of cognitive mapping with these data. www.biorxiv.org/content/10.1...
biorxiv.org
Identifying representational structure in CA1 to benchmark theoretical models of cognitive mapping
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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