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Julie Ostrander

@jostrander.bsky.social
251 followers 142 following 18 posts

Associate Professor of Medicine at the University of Minnesota.

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Julie Ostrander @jostrander.bsky.social · 18/12/2025
A new PI level unlocked! The first PhD student in my lab defended today. Congratulations Dr. Natasha Roman Ortiz!
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Julie Ostrander @jostrander.bsky.social · 25/06/2025
This has been such an exciting collaborative project with the lab of @mjsikora.bsky.social! Stay tuned… more to come!
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Matt Sikora @mjsikora.bsky.social · 23/06/2025
Congrats to Dr. Maggie Musick on her 1st lead-author study in the lab! This #lobular project with @jostrander.bsky.social has been so much fun over the last few years. Blue-torial soon, after a grant gets out the door this week 🫠
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Becca Riggins 🇻🇮 ⛵️🧪 @profriggins.bsky.social · 23/06/2025
Cool stuff 🎉👏 @mjsikora.bsky.social @jostrander.bsky.social #bcsm #lobular 🧪🧬
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Jeremy Berg @jeremymberg.bsky.social · 31/05/2025
ASSIGNMENT: COMMENT ON SCHEDULE F 1 week left to comment about Schedule F, potentially making NIH institute and center director essentially political appointees. www.regulations.gov/commenton/OP... 1/n
regulations.gov
Regulations.gov
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Scott Delaney @scott-delaney.bsky.social · 27/05/2025
NIH has terminated at least 565 previously awarded training grants, fellowships, and early career awards so far this year, and they've awarded 1,100 fewer new ones. That's ~1,600 fewer grants supporting new scientists than we'd have had if just a few thousand more folks voted for Harris over Trump.
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Kayla B @queenofthesouth.bsky.social · 12/05/2025
My daughter’s speech therapist went out of business because Medicaid reimbursement rates were too low. We do not have Medicaid. I’m going to keep posting this until people understand that when Medicaid gets cut *everyone* loses services.
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Jessica Tollkuhn @tollkuhn.bsky.social · 12/05/2025
please tell your letter-writers if you get the job/award!
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Dana R. Fisher (aka the Apocalyptic Optimist) @fisherdanar.bsky.social · 25/04/2025
My new piece in @rollingstone.com : “Our democracy is made up of reciprocal ties between and among all of us, and AmeriCorps strengthens these ties. We will all feel the loss of AmeriCorps...and our democracy will pay the price.” www.rollingstone.com/politics/pol...
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Jeremy Berg @jeremymberg.bsky.social · 23/04/2025
The notice and COMMENT PERIOD OPENED TODAY AND CLOSES MAY 23. Anyone who would like to register an objection or comment should go to this page and click on the green “public comment” button at the top: www.federalregister.gov/documents/20... 6/n
federalregister.gov
Improving Performance, Accountability and Responsiveness in the Civil Service
The Office of Personnel Management (OPM) is proposing a rule to increase career employee accountability. Agency supervisors report great difficulty removing employees for poor performance or misconduc...
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Stand Up for Science! @standupforscience.net · 02/04/2025
Please take a moment to read and sign this excellent letter. Over 3,500 signature so far!
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Jeremy Berg @jeremymberg.bsky.social · 29/03/2025
Analysis of Terminated NIH Grants with Word Clouds First, using the titles of grants not to Columbia... Gender and DEI predominate
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Pam Herd @pamherd.bsky.social · 30/03/2025
Trump has cut the NIH budget by more than half in defiance of Congressionally mandated appropriations for the agency. No comparison historically, not even the Great Recession. This is clearly not legal and Congress needs to address it.
Graph from the Washington Post showing declines in spending at NIH. New grants cut from 1 billion to around 400 million. Overall grants down from 4.5 billion to 2.4 billion.
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Daniel Gorelick @danielgorelick.bsky.social · 25/03/2025
Review quality also maintained because rejection rate was similar among Fast & Fair vs conventional peer review...and Biology Open now publish all reviews, so readers can see for themselves
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Biology Open @biologyopen.bsky.social · 25/03/2025
We are excited to be launching the next phase of our Fast & Fair peer review initiative: offering high-quality peer review within 7 working days. #fastandfairpeerreview Read the Editorial by EiC Daniel Gorelick @danielgorelick.bsky.social at: bit.ly/4kYD1mL
Fast & Fair peer review

A new initiative offering high-quality peer review within 7 working days of submission

Biology Open
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Katie Loth @klothphd.bsky.social · 21/03/2025
Providing every child access to a high quality education is the most important thing we can do to protect our future. An educated workforce drives the economy, scientific innovation and secures our countries place as a world leader. Eliminating the #doe will hurt all of us. #departmentofeducation
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Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 20/03/2025
The general vibe we are getting across #NIH institutes is deeply bleak — that the agency is nearly, if not already dead. Top people are leaving or have left. Nearly everyone's looking for other jobs. People still care about what NIH was, but are growing resigned to its death. 1/
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Matt Sikora @mjsikora.bsky.social · 15/03/2025
Still wrapping my head around 57% cut to CDMRP (cdmrp.health.mil) funding in CR. CDMRP funds some of the most innovative high-risk/high-reward research in biomedical science, and in it all, includes patient advocates. BEFORE the cut, the breast cancer program funded 3-5% of proposals. What now?
cdmrp.health.mil
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Julie Ostrander @jostrander.bsky.social · 15/03/2025
www.google.com/url?q=https:...
google.com
Urge Congress to Oppose the SPARE Act
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Julie Ostrander @jostrander.bsky.social · 14/03/2025
@amyklobuchar.com please don't vote for this CR as it is!!
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Julie Ostrander @jostrander.bsky.social · 14/03/2025
If anyone is wondering why the republican's CR is worse than a government shutdown... The illegal spending cuts they have instituted in the last 2 months will become legal. There will be no recourse in the courts. Dems need to at least TRY and fight and negotiate! Call your SENATORS!
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Bita Moghaddam @bita137.bsky.social · 09/03/2025
The House Continuing Resolution budget “adjustments” for NIH are drastic. Here are some examples:
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dustinthewind357.bsky.social @dustinthewind357.bsky.social · 10/03/2025
Please call your Congressmen today to tell them that you support children's cancer research and not to cut Dept of Defense CDMRP funding for cancer research. Vote No on the job-killing, kid-killing Continuing Resolution (CR) tomorrow. Also breast cancer, prostate cancer, Parkinson’s research, etc.
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Katie Hinde @mammalssuck.bsky.social · 09/03/2025
Because one of the hats I wear is 'researcher with expertise in milk, lactation, & breastfeeding' I encounter folks who think breastfeeding is more important than vaccination... Yes, I am about to launch a
media.tenor.com
a man in a suit and tie is saying `` chaos grenade '' while standing in an office .
Alt: a man in a suit and tie is saying `` chaos grenade '' while standing in an office pretending to throw said grenade.
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Julie Ostrander @jostrander.bsky.social · 08/03/2025
Stand up for Science at the MN Capital. Lots of great speakers talking about the impact of the current administration on scientific and medical research, public health, the environment, and DEI. @drnegillis.bsky.social @standupforscience.bsky.social
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Julie Ostrander @jostrander.bsky.social · 06/03/2025
@docfanning.bsky.social at UMN today telling us about his work on ER structure and Dickkopf-1. My personal favorite was the cameo appearance of PELP1. Great talk Sean!
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Julie Ostrander @jostrander.bsky.social · 27/02/2025
www.eventbrite.com/e/stand-up-f...
eventbrite.com
Stand Up for Science 2025 - St. Paul, MN
Stand up for science with us on March 7th, 2025, because science is for everyone! More info at www.standupforscience2025.org
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Nima Sharifi MD @nimasharifimd.bsky.social · 23/02/2025
About $74 million in US govt funding (including NIH) went into developing enzalutamide - a multibillion dollar drug that prolonged life for countless men with prostate cancer. Why would anyone cut this support? We need more, not less! @ascocancer.bsky.social @theaacr.bsky.social
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Jeremy Berg @jeremymberg.bsky.social · 21/02/2025
New York Times article now up on Federal Register stuff. www.nytimes.com/2025/02/21/s... 1/n
nytimes.com
Trump Administration Stalls Scientific Research Despite Court Ruling (Gift Article)
Using an arcane law, officials have effectively delayed funding from the National Institutes of Health, leaving medical studies in jeopardy.
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Kristen Kwan @blockintheback.bsky.social · 20/02/2025
Current status: www.nature.com/articles/d41...
nature.com
Revealed: NIH research grants still frozen despite lawsuits challenging Trump order
The Trump administration is exploiting a loophole to keep a funding freeze in place, leaving researchers in limbo.
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Dr. Becca @docbecca.bsky.social · 17/02/2025
If anyone has been in touch with press covering the NIH situation broadly (firings, funding freeze etc), please encourage them to cover the sinister way in which HHS is preventing grant review and funding from happening, by blocking posting to the Federal Register.
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Julie Ostrander @jostrander.bsky.social · 15/02/2025
@amyklobuchar.com and @smith.senate.gov were at the Masonic Cancer Center, University of MN today raising awareness about terrible NIH policies that are trying to be implemented by the current administration.
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Matt Sikora @mjsikora.bsky.social · 11/02/2025
Tiny victory in the chaos: Submitted an R21 today w @docfanning.bsky.social & @jostrander.bsky.social to NCI Clinical & Translational Exploratory/Dev. program, to develop new anti-estrogens tailored for #lobular breast cancer. Project all via @nrimpact.bsky.social collab. Onward, dauntless 💪
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Bita Moghaddam @bita137.bsky.social · 10/02/2025
If you are a NIH funded researcher and your state is not on this list, you need to be calling your AG office
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Prasad Jallepalli, MD, PhD @prasad.bsky.social · 08/02/2025
this is a good time to note that the proposed candidate for NIH director has never run a lab, cared for patients, led a major research and healthcare institution, or been a principal investigator on an NIH grant
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Karen James @kejames.bsky.social · 08/02/2025
Look up the impact of NIH funding in your state: www.unitedformedicalresearch.org/nih-in-your-...
unitedformedicalresearch.org
NIH In Your State - United For Medical Research
Select a state on the map to see the impact of NIH funding across America.
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Krutika Kuppalli, MD FIDSA @krutikakuppalli.bsky.social · 08/02/2025
NIH doesn’t just support infectious disease research—it drives breakthroughs in cancer, childhood diseases, heart disease, diabetes & more. Thanks to NIH, we have: 💉 Cancer immunotherapy ❤️ Cholesterol-lowering statins 🩸 Insulin for diabetes Investing in NIH = investing in life-saving discoveries.
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Matt Sikora @mjsikora.bsky.social · 02/01/2024
@jostrander.bsky.social and I had the opportunity to write a commentary on @profriggins.bsky.social latest work in JES - @zmadake2.bsky.social - looking toward really cool implications for understanding and leveraging the unique metabolism of lobular breast cancer. academic.oup.com/jes/advance-...
academic.oup.com
A path to precision metabolic treatment in breast cancer: riluzole, glutamate signaling, and invasiv...
Matthew J Sikora, Julie H Ostrander; A path to precision metabolic treatment in breast cancer: riluzole, glutamate signaling, and invasive lobular carcinoma, Jo
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bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 30/10/2023
Co-regulator activity of Mediator of DNA Damage Checkpoint 1 (MDC1) is associated with DNA repair dysfunction and PARP inhibitor sensitivity in lobular carcinoma of the breast www.biorxiv.org/content/10.1101/202…
biorxiv.org
Co-regulator activity of Mediator of DNA Damage Checkpoint 1 (MDC1) is associated with DNA repair dysfunction and PARP inhibitor sensitivity in lobular carcinoma of the breast https://www.biorxiv.org/content/10.1101/2023.10.29.564555v1
Invasive lobular carcinoma of the breast (ILC) are typically estrogen receptor alpha (ER)-positive a
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Matt Sikora @mjsikora.bsky.social · 30/10/2023
New #lobular breast cancer study from Sikora Lab is up, after buzz re: PARP inhibitors at #ILCSymposium! We think ILC-specific co-reg fxn of MDC1 allows ER:MDC1 to control endo response/resistance in ILC, at the cost of a DNA repair dysfunction that can be hit with PARPi. Thread: 1/8
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