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Julie Ledoux

@jldx.bsky.social
51 followers 81 following 3 posts

Postdoctoral researcher in computational structural biology @ Laboratory of Theoretical Biochemistry, Paris.

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Reposted by Julie Ledoux
Emily M. Bender @emilymbender.bsky.social · 01/07/2026
For more on how to talk about tech sold as "AI" in more precise terms: buttondown.com/maiht3k/arch...
buttondown.com
How to talk about
Emily M. Bender and Nanna Inie In our op-ed for Tech Policy Press ("We Need to Talk About How We Talk About 'AI'"), we made the case against the...
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Mel Andrews @bayesianboy.bsky.social · 17/06/2026
When utilized in literature review, LLMs consistently 1. fail to mention female authors in female-led literatures, 2. insist that men are more influential or more heavily cited when this is contradicted by objective citation counts, and 3. attribute women’s work to hallucinated male scholars.
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Randall Munroe @xkcd.com · 14/05/2026
Results Age xkcd.com/3245/
Comic: Implications of the age of the posts you see when you Google an error message. [Grayed out error code with unreadable post. Post date of 3 years ago is enlarged with a text bubble. Table with three columns for age of post, what it means, and probability of a fix. 2 hours ago: There’s an infrastructure outage; very high–just wait. 5 days ago: A recent update broke something big; high, but you might have to wait for a patch. 3 months ago: A new product isn’t working for some users; decent chance of a solution in the replies. 2 years ago: You’ve run into an edge case; low, but maybe the replies can help with troubleshooting. 13 years ago: You’re the only person with this problem; very low–post is likely not relevant. 24 years ago: Oh god how is the internet this old; maybe whoever posted this message has kids who can help you.
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Phil Biggin @philbiggin.bsky.social · 06/05/2026
Congratulations to Bjarne Feddersen for his work on benchmarking umbrella sampling workflows for PMF calculations of membrane permeation! Systematic work that provides guidance on how to approach these to minimise compute resource. @oxfordbiochemistry.bsky.social. pubs.acs.org/doi/10.1021/...
pubs.acs.org
Umbrella Sampling Workflows for Fast-Converging PMF Calculations without Artificial WHAM Constraints
Umbrella sampling is a powerful tool to investigate the underlying free-energy landscapes that govern the permeation properties of small molecules through complex lipid bilayers. However, obtaining co...
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Reposted by Julie Ledoux
bioRxiv Biophysics @biorxiv-biophys.bsky.social · 26/10/2025
Role of Water Models in Simulations of Ion Conduction in Potassium Channels www.biorxiv.org/content/10.1101/202…
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bioRxiv Biophysics @biorxiv-biophys.bsky.social · 09/10/2025
GROMODEX: Optimisation of GROMACS Performance through a Design of Experiment Approach www.biorxiv.org/content/10.1101/202…
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bioRxiv Bioinfo @biorxiv-bioinfo.bsky.social · 28/04/2026
Integrating the MARTINI2 Coarse-Grained Force Field into HADDOCK3 for Faster Modelling of Large Biomolecular Complexes www.biorxiv.org/content/10.64898/20…
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Julie Ledoux @jldx.bsky.social · 24/04/2026
So it is out! 🎉 I am so excited to share our preprint with Fabio Sterpne and @baam93.bsky.social on the development of a force field for oligourea foldamers, new self-assembling polymers of unnatural amino acids, designed for water desalination membranes. www.biorxiv.org/content/10.6...
biorxiv.org
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Admirable Women @admirablewomen.bsky.social · 10/04/2026
Biochemist Elizabeth Bugie co-discovered streptomycin (with Selman Waksman), the first antibiotic against Mycobacterium tuberculosis. Waksman went on to win the 1952 Nobel Prize for Medicine & took full credit for the discovery. Bugie died #OTD in 2001. #WomenInSTEM #MatildaEffect (1/2)
A black-and-white historical photograph of Elizabeth Bugie, a pioneering biochemist, working in a laboratory. She is shown from the waist up, wearing a short-sleeved white top and focusing intently on her work.

She has dark, shoulder-length hair and is holding a piece of glassware connected to a black rubber tube, seemingly adjusting a filtration or distillation setup. Several Erlenmeyer flasks and glass funnels sit on the bench in front of her. In the background, shelves are filled with numerous glass chemical bottles of various sizes, and a window with multiple panes is visible to the right.
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Joe Greener @jgreener64.bsky.social · 01/04/2026
On this 1st April I'm happy to release a technical report from our startup MirageBio, describing a new protein structure model with state-of-the-art performance. jgreener64.github.io/posts/techni...
jgreener64.github.io
MirageBio technical report
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RCSB Protein Data Bank @rcsbpdb.bsky.social · 26/03/2026
Use the AI-Powered 3D Structure Similarity Search This new RCSB PDB feature delivers faster and more scalable structural comparisons across experimentally determined and predicted Computed Structure Models (CSMs).
rcsb.org
Use the AI-Powered 3D Structure Similarity Search
This new feature delivers faster and more scalable structural comparisons across experimentally determined and predicted Computed Structure Models (CSMs).
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Reposted by Julie Ledoux
Dr. Hab Sophie Sacquin-Mora @sacquin-mo.eurosky.social · 05/03/2026
L'évènement #ReCombinaisons est de retour à @pasteur.fr en 2026 avec un programme alléchant ! (On y retrouvera notamment @jeanneadebats.bsky.social et @audreypleynet.bsky.social !)
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Nature @nature.com · 05/01/2026
Book review 📚 These women helped to shape quantum mechanics — it’s time to recognize them go.nature.com/3Ls2yYu
go.nature.com
These women helped to shape quantum mechanics — it’s time to recognize them
An astute book redresses our collective perception of a field that became known as ‘boys’ physics’.
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Mariana Lenharo @marilenharo.bsky.social · 27/08/2025
The chance encounter of an economist, a pathologist and physicist resulted in a highly multidisciplinary study that used an epidemiological model to trace the spread of rumors in the early days of the French Revolution. I had the chance to cover this fascinating research for @nature.com
nature.com
An abiding mystery of the French Revolution is solved — by epidemiology
The period of panic and unrest called the Great Fear was triggered by deliberately spread rumours, according to methods borrowed from pandemic playbooks.
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Julie Ledoux @jldx.bsky.social · 01/07/2025
I LIVE for catchy methods names and funny conference presentation titles
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Reposted by Julie Ledoux
PHD Comics @phdcomics.com · 28/06/2025
It's inevitable
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Nature @nature.com · 02/06/2025
Studies point to several reasons why fewer women than men are submitting their work go.nature.com/3HlUFS8
go.nature.com
Gender equality in research publishing is a responsibility for everyone
A concerted effort is needed to support women in their choice of journal when submitting their manuscript.
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Rafeeque Mavoor @rafeequemavoor.bsky.social · 13/05/2025
🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!
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Alexis Verger 🧬🧫🧪 @alexis-verger.cpesr.fr · 06/05/2025
Choose Europe (France) for Science #ESR (credit : Jérôme Sié)
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PHD Comics @phdcomics.com · 18/03/2025
Where you sit 🤓😎😴
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Eric Lagadec @ericlagadec.bsky.social · 18/04/2025
Et voilà, les plus grands spécialistes de tout, les fameux toutologues, commencent à annoncer que l'on a trouvé du phytoplancton intersidéral.... Nous, scientifiques, devons faire attention à notre manière de communiquer. Ce n'est pas le moment de perdre la confiance des citoyens !
Idiriss aberkane annonce que l'on a trouve du phytoplancton dans l'espace
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Antonio Monari @antoniomonari.bsky.social · 16/04/2025
If you want to know how to fight bacterial resistance @france.theconversation.com Pour comprendre comment contrer la résistance bactérienne @france.theconversation.com @barbault.bsky.social @upcite.bsky.social @ctm-itodys.bsky.social @itodys.bsky.social theconversation.com/resistance-b...
theconversation.com
Résistance bactérienne aux antibiotiques : mieux la comprendre et mieux la contrer
En comprenant comment les bactéries résistent aux antibiotiques, on pourrait inventer de nouvelles méthodes pour améliorer les traitements des infections.
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Reposted by Julie Ledoux
Onisillos @onisillos.bsky.social · 15/04/2025
Given discussions at I had at #ESCMIDGlobal, it might be useful for new researchers to know how a journal editor screens submissions (obviously this is my approach and so it might differ for others).
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Dr. Jules Marien @marienj.bsky.social · 11/04/2025
We (@sacquin-mo.bsky.social, Chantal Prevost and I) teamed up with @etiennereboul.bsky.social and @ataly.bsky.social to design a parallelized MDAKit implementation of the Proteic Menger Curvatures. Local protein dynamics and backbone flexibility have never been easier and faster to compute 😁
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Julie Ledoux @jldx.bsky.social · 10/04/2025
media.tenor.com
a man in a maroon shirt sits at a desk with a book
ALT: a man in a maroon shirt sits at a desk with a book
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Reposted by Julie Ledoux
Nature @nature.com · 24/03/2025
Research suggests that contrary to scientists' worries, there is no reputational penalty for shared first authorships, even for the person named second ― at least under experimental conditions1. go.nature.com/4c46IPm
go.nature.com
Does sharing first authorship on a paper carry a penalty? What the research says
Study dispels myth that order of names in a paper’s author list dictates perception of success.
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Irina Bezsonova @irinabezsonova.bsky.social · 15/03/2025
You can download my protein structure-inspired artwork from pdb webpage: pdb101.rcsb.org/sci-art/bezs... @rcsbpdb.bsky.social @pdbeurope.bsky.social #sciart
pdb101.rcsb.org
PDB101: Irina Bezsonova Gallery
PDB-101: Training, Outreach, and Education portal of RCSB PDB
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Nature @nature.com · 07/03/2025
Academia’s often misguided view is that resilience is the ability to adapt and overcome challenges or adversity, but such an attitude can mask a toxic lab culture, say some researchers. go.nature.com/4kv5ro4
go.nature.com
‘I was told to toughen up’: is academia getting resilience all wrong?
Being repeatedly told to bounce back and develop a thicker skin can mask a toxic lab culture.
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Willem van Schaik @wvschaik.bsky.social · 04/02/2025
Shame on you @asm.org, shame on you.
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