Jim Januzzi @jimjanuzzi.bsky.social · 23/05/2026Affirmative--Curtis had idiopathic epilepsy, which was exacerbated by lack of sleep and possibly by photic stimulation from the lighting on stage. Prior to dying, he unsuccessfully tried to overdose on his phenobarb. Give me an intersection of medicine and music and I'll lean in anytime. 020
Reposted by Jim JanuzziAmerican College of Cardiology @accintouch.bsky.social · 11/11/2025“Philanthropy can lead to some really remarkable changes in how leadership can be cultivated, research can be distributed and health care can be improved.” 🗣️ ACC Philanthropic Fundraising Committee Chair Dr. @jimjanuzzi.bsky.social 📽️ bit.ly/4qQrkBv #ACCPresident @chriskramermd.bsky.social 052
Jim Januzzi @jimjanuzzi.bsky.social · 31/10/2025I don't post much anymore, but I felt it worth reminding our colleagues that "follow up with your cardiologist ASAP" is not a guideline supported move nor a therapeutic intervention for someone discharged with ongoing new onset atrial flutter with RVR on a Friday afternoon. #cardiosky 5144
Reposted by Jim JanuzziJACC Journals @jaccjournals.bsky.social · 29/09/2025Selective in vitro enhancement of cardiac myosin motor function and myofilament force generation by danicamtiv prompted clinical evaluation. A short course of danicamtiv was generally well tolerated in participants with #DCM bit.ly/4mE3vcM #HFSA2025 #JACC #cvGenetics @jimjanuzzi.bsky.social 043
Reposted by Jim JanuzziJonathan Davis, MD, MPHS @jonathandavishf.bsky.social · 14/05/2025Short & sweet! Check out our review of #SGLT2i & #GLP1RA in #HeartFailure! Great work Jose Lopez & team! @ucsfcardiology.bsky.social @amitgoyalmd.bsky.social @robmentz.bsky.social @dranulala.bsky.social @jimjanuzzi.bsky.social @sjgreene-md.bsky.social www.uscjournal.com/articles/sho...uscjournal.comThe Short and Sweet on Sodium–Glucose Cotransporter Inhibitors and Glucagon-like Peptide-1 Receptor Agonists in Heart FailureHeart failure (HF) affects 6 million people in the US, and type 2 diabetes (T2D) is a significant risk factor for HF. Since 2008, regulatory agencies have required cardiovascular safety trials 172
Reposted by Jim JanuzziShalen Fairbanks @shaykim.bsky.social · 10/05/2025Great presentation by @jimjanuzzi.bsky.social at #ACCAsia in Singapore on optimizing decongestion using diuretics and GDMT in patients with HF. Access more HF resources in the @accintouch.bsky.social Guidelines Hub: acc.org/guidelines 021
Reposted by Jim JanuzziParham Eshtehardi MD @cardioobdoc.bsky.social · 06/05/2025Get to Know Your Leaders | Leading With Purpose: Meet Chris Kramer, MD, FACC @chriskramermd.bsky.social #CardiologyMagazine #CardioSky www.acc.org/Latest-in-Ca... @accintouch.bsky.social @jaccjournals.bsky.social @jimjanuzzi.bsky.social @drmarthagulati.bsky.social @vietheartpa.bsky.social 097
Reposted by Jim JanuzziB Grrl @bgrrl.bsky.social · 16/04/2025Hope for tx of nHCM: According to the company, this partial fatty acid oxidation (pFOX) inhibitor is an oral compound that promotes a shift in the heart’s preference from fatty acids to glucose, resulting in energy generation by the mitochondria. #HCM #CardioSky #Cardiomyopathy #Cardiologypharmaceutical-business-review.comImbria secures $57.5m to advance ninerafaxstat through Phase IIb trialImbria has secured $57.5m in a Series B funding round to support the progression of ninerafaxstat through a Phase IIb trial in nHCM. 071
Reposted by Jim JanuzziHenry Han @hancardiomd.bsky.social · 15/04/2025Clinical and plasma proteomic characterization of heart failure with supranormal left ventricular ejection fraction: An emerging entity of heart failure #EJHF @escardio.bsky.social #CardioSky @shelleyzieroth.bsky.social @jimjanuzzi.bsky.social @drmarthagulati.bsky.social @cardioobdoc.bsky.social 133
Jim Januzzi @jimjanuzzi.bsky.social · 06/04/2025When I see something like this, I promise the patient that with the effort of initiating and titrating #GDMTworks, they can expect a bounce in their LVEF. In this case--since she's naive to therapy--likely a lot. 010
Jim Januzzi @jimjanuzzi.bsky.social · 03/04/2025Back to the Garden with @julijanuzzi.bsky.social @celticsnba.bsky.social 1130
Jim Januzzi @jimjanuzzi.bsky.social · 01/04/2025I am so incredibly grateful to the @accintouch.bsky.social for the honor of being named the 2025 Distinguished Clinical Researcher. I am blessed to have stood on the shoulders of giants during my career and am thankful to @mgbresearch.bsky.social and #BaimInstitute for support. 3316
Reposted by Jim JanuzziAnju Bhardwaj MD @docbhardwaj.bsky.social · 01/04/2025Congratulations @jimjanuzzi.bsky.social Very well deserved 👏👏 053
Reposted by Jim JanuzziDr Ada Stefanescu @dradastefanescu.bsky.social · 01/04/2025Congratulations @jimjanuzzi.bsky.social on your @accintouch.bsky.social Distinguished Scientist Award!! #ACC25 3155
Reposted by Jim JanuzziAmerican College of Cardiology @accintouch.bsky.social · 31/03/2025Congratulations to new #ACCPresident Christopher M. Kramer, MD, FACC! Inspired by a movie classic, he shared: “Today I want to talk to you about two Fantastic Voyage-Related themes: innovation and mentorship.” 💬 bit.ly/41RJlF6 @ChrisKramerMD #ACC25 #ACCLeadership 1198
Reposted by Jim JanuzziCristina Popa @nephroseeker.medsky.social · 30/03/2025FRESH-UP Trial #ACC25 #medsky RCT comparing liberal vs restricted fluid intake (≤1500 ml/d) in 504 pts with stable chronic HF 🌊No difference in status health quantified by Kansas City Cardiomyopathy Questionnaire at 3 mths 🌊 More thirst distress with restriction www.nature.com/articles/s41... 02415
Reposted by Jim JanuzziJoe Cuthbert @jjcuthbert.bsky.social · 31/03/2025Fluid restriction associated with trend to worse QoL and greater thirst in stable outpatients with HF. No difference in safety. www.nature.com/articles/s41...nature.comLiberal fluid intake versus fluid restriction in chronic heart failure: a randomized clinical trial - Nature MedicineWhile fluid restriction is typically recommended for patients with chronic heart failure, this randomized clinical trial showed no difference in health status, as assessed by patient-reported outcomes... 112
Reposted by Jim Januzziallisonghaysmd.bsky.social @allisonghaysmd.bsky.social · 30/03/2025Terrific @accintouch.bsky.social @acc25 session on the intersection of heart failure and imaging. Great job @purviparwani.bsky.social @michaelsalerno.bsky.social moderating the interesting case-based discussions @jimjanuzzi.bsky.social 1114
Jim Januzzi @jimjanuzzi.bsky.social · 27/03/2025Opening day for the @redsox.com Let’s go #MLB2025 #DirtyWater @heartbobh.bsky.social 060
Jim Januzzi @jimjanuzzi.bsky.social · 24/03/2025Happy birthday to a person who makes the world more beautiful. Walking the beach where just a few months ago our buddy was having the time of his life. Glad to share the moment together. There are blue skies beyond this. Happiest of birthdays, RSJ. @robertasensen.bsky.social 140
Jim Januzzi @jimjanuzzi.bsky.social · 22/03/2025I did not have habitually watching eaglets on my 2025 bingo card but we are completely here for #JackieandShadow and their babies. #FOBBV #eagles @robertasensen.bsky.social 1120
Jim Januzzi @jimjanuzzi.bsky.social · 20/03/2025No idea--as hard as it was for me to do it with 18K+ followers, I suspect it'd be harder for him with half a million... 200
Jim Januzzi @jimjanuzzi.bsky.social · 19/03/2025I haven't posted there in basically months and was using it largely to lurk and check news/scores. At the end of the day--definitely not worth it. 191
Jim Januzzi @jimjanuzzi.bsky.social · 19/03/2025Enough is enough. I have deleted my Twitter account. Not worth it anymore. 4158127
Jim Januzzi @jimjanuzzi.bsky.social · 18/03/2025One more day to purchase tickets! www.acc.org/75thGala #cardioskyacc.org75thgala - American College of CardiologyThe ACC Foundation Anniversary Gala will unite our members, friends and partners to celebrate the remarkable achievements of the past 75 years and raise funds to continue advancing our Mission. 122
Jim Januzzi @jimjanuzzi.bsky.social · 03/03/2025thanks Rick! These days, finding the happy moments is more important than ever. 010
Jim Januzzi @jimjanuzzi.bsky.social · 03/03/2025Courtside @thebostonceltics.bsky.social with @robertasensen.bsky.social and the fam. 1100
Reposted by Jim JanuzziParham Eshtehardi MD @cardioobdoc.bsky.social · 19/02/2025In pts undergoing 99mTc PYP imaging for suspected #ATTR, hs-cTnT & NT-proBNP can effectively rule out diagnosis, although in a small subset of patients #CardioSky www.jacc.org/doi/10.1016/... @jaccjournals.bsky.social @vietheartpa.bsky.social @load-dependent.bsky.social @jimjanuzzi.bsky.social 066
Jim Januzzi @jimjanuzzi.bsky.social · 31/01/2025a broken clock is correct twice a day...but it's still broken. 041
Jim Januzzi @jimjanuzzi.bsky.social · 12/01/2025Game time, Courtside with @julijanuzzi.bsky.social @thebostonceltics.bsky.social 1130
Jim Januzzi @jimjanuzzi.bsky.social · 03/01/2025Send me an email--come on, do it.media.tenor.coma man with a beard and mustache is smiling and says `` do it '' .ALT: a man with a beard and mustache is smiling and says `` do it '' . 160
Reposted by Jim JanuzziParham Eshtehardi MD @cardioobdoc.bsky.social · 02/01/2025Aortic Stenosis, Heart Failure, & Aortic Valve Replacement #CardioSky #MedSky #TAVR #TAVI @jama.com @jimjanuzzi.bsky.social @robmentz.bsky.social @drdevireddy.bsky.social @hvanspall.bsky.social @anastasiasmihaili.bsky.social jamanetwork.com/journals/jam... 0168
Jim Januzzi @jimjanuzzi.bsky.social · 26/12/2024Really interesting data about how BAG3 variants modify cardiomyopathy risk. 071
Jim Januzzi @jimjanuzzi.bsky.social · 25/12/2024Thank you! A gift from @robertasensen.bsky.social 020
Jim Januzzi @jimjanuzzi.bsky.social · 25/12/2024Merry Christmas to all My favorite gift of the season is now on the tree. #IYKYK 170
Reposted by Jim JanuzziGreg Bryson @glbryson.bsky.social · 21/12/2024Older news but still noteworthy. Among patients with HFrEF and HFpEF, withdrawal of SGLT2i led to increased CV death, HF symptoms, fasting glucose, BP, BNP and decreased Hb. Events occurred within 30 days of withdrawal. Are we sure that's what we want to do preop? www.ahajournals.org/doi/10.1161/...ahajournals.orgBlinded Withdrawal of Long-Term Randomized Treatment With Empagliflozin or Placebo in Patients With Heart Failure | CirculationBACKGROUND: It is not known whether the benefits of sodium-glucose cotransporter 2 inhibitors in heart failure persist after years of therapy. METHODS: In the EMPEROR-Reduced (Empagliflozin Outcome ... 091
Jim Januzzi @jimjanuzzi.bsky.social · 21/12/2024Thanks Rick—I wish you a wonderful holiday season. 020
Jim Januzzi @jimjanuzzi.bsky.social · 21/12/2024The holidays begin with a little snow. It’s hard to tell but these trees are 30-40 feet tall. Happy Friday, all. 2100
Reposted by Jim JanuzziHarlan M. Krumholz @hmkyale.bsky.social · 11/12/2024Patients are also welcome to suggest research questions. For all: Submit your questions here: www.jacc.org/priorities-f... Together, we can address the evidence gaps that matter most! #Cardiology #ClinicalResearch #HeartHealthjacc.orgJACC | Priorities for Evidence Generation 1168
Reposted by Jim JanuzziHarlan M. Krumholz @hmkyale.bsky.social · 11/12/2024Clinicians, your voice matters! 🩺 @JACCJournals & @US_FDA are teaming up to tackle urgent evidence gaps in cardiovascular care. Share the key questions you face in practice about FDA-regulated products and help shape the future of research. www.jacc.org/doi/10.1016/...jacc.orgGiving Cardiovascular Clinicians a Voice in Evidence Generation: A Collaboration Between FDA and JACC 12616
Reposted by Jim JanuzziChris Georgenes @bostondrummer.bsky.social · 07/12/2024It Ain’t Over ‘Till It’s Over by Lenny Kravitz #drumcover 092
Reposted by Jim JanuzziHarriette Van Spall MD MPH 🇨🇦 @hvanspall.bsky.social · 02/12/2024An R2 as high as 90% is rare!! 🔺In this metaanalysis of #HF #RCTs, Tx effect of interventions on HF 🏥s & all-cause 🏥s were HIGHLY correlated (R2 = 90.1%; 95% CI 62.3%-99.8%) 🔺HHF is a suitable clinical endpoint in HF RCTs for many reasons, including the one above 084
Reposted by Jim JanuzziHarlan M. Krumholz @hmkyale.bsky.social · 28/11/2024As Editor-in-Chief of JACC, I’m thankful for the inspiring community that advances cardiovascular health. From groundbreaking submissions to engaged readers and reviewers, and our team, you make our journey possible. Here’s my Thanksgiving message of gratitude:buff.lyHappy Thanksgiving | JACCJACC editor-in-chief Harlan M. Krumholz, MD, SM relays his gratitude for the past few months and enthusiasm for staff, editors, reviewers, readers, and autho... 0246
Jim Januzzi @jimjanuzzi.bsky.social · 01/12/2024Starting the day with some music theory and coffee with #RickBeato www.youtube.com/watch?v=FaMP...youtube.comThe Beatles: What Makes This Song Great?YouTube video by Rick Beato 190
Jim Januzzi @jimjanuzzi.bsky.social · 30/11/2024www.tctmd.com/news/once-bu...tctmd.comOnce Burned, Twice Shy, Cardiologists Ditch X for BlueskyThough X (formerly Twitter) was once a place many cardiologists found community and opportunity, many are jumping ship. 0132