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Jia-Hou (JH) Poh

@jiahou-poh.bsky.social
129 followers 199 following 9 posts

Research Asst Professor, National University of Singapore, Yong Loo Lin School of Medicine. Cognitive neuroscientist curious about Motivation and Memory. poh-brainmemlab.github.io/BrainMemL…

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Reposted by Jia-Hou (JH) Poh
Denise J. Cai, Ph.D. @denisejcai.bsky.social · 30/09/2026
NEW: The anterior hypothalamic nucleus acts like a volume knob for stress, scaling the brain’s response to threatening events 🧠 Read the Cai Lab's latest paper, led by @zachtpennington.bsky.social, in @nature.com 🎉 www.nature.com/articles/s41... More: bsky.app/profile/did:...
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Tobias Egner @tobiasegner.bsky.social · 18/09/2026
Job Alert: Our department is looking to recruit an eminent scholar for a distinguished, endowed professorship (full professor, tenured) in the domain of human neuroscience with high clinical relevance. Please broadcast widely! For application information, see academicjobsonline.org/ajo/jobs/32753
academicjobsonline.org
Duke University, Psychology and Neuroscience
Job #AJO32753, Professor (tenured), Psychology and Neuroscience, Duke University, Durham, North Carolina, US
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Mariam Aly @mariamaly.bsky.social · 04/09/2026
How do we prevent memories from competing to guide attention? More distinct hippocampal representations for competing memories are linked to precise preparatory coding in visual cortex & more accurate eye movements to target locations. Thrilled to share this work by the incomparable Serra Favila!
nature.com
Hippocampal mechanisms underlying the resolution of competition in memory and perception - Nature Communications
Memory and perception both require selecting behaviorally relevant information. Here, the authors show that more distinct hippocampal memories are linked to precise anticipatory signals in visual cort...
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Jin Ke @jinke.bsky.social · 27/08/2026
Our paper is now out in @nathumbehav.nature.com! By periodically probing ongoing thoughts during resting-state fMRI, we found that these rich and idiosyncratic thoughts can be decoded from brain network dynamics and help explain links between functional brain architecture and everyday behavior.
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Taylor Chamberlain @tchamberlain.bsky.social · 19/08/2026
Sometimes we know an experience is important in the moment. Other times, its importance only becomes clear after the fact. Do these two cases have different consequences for memory? In our new paper we found that both kinds of prioritization impact memory in different ways! doi.org/10.1162/OPMI...
doi.org
Prioritizing Detailed Item Memories Through Post-Encoding Motivation Requires Consolidation
Abstract. Prioritizing memories that are motivationally salient is adaptive for goal-directed behavior, ensuring that information being retained is the most relevant to future goals. Past research dem...
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Sami Yousif @samiyousif.bsky.social · 18/08/2026
There's been discussion about Prolific's dynamic pricing model here on bluesky. To learn more about this (and to make loads of cash, apparently!) I decided to become an actual Prolific participant. See thread below, but TLDR: What's happening on Prolific is not what I expected!👇
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Deepu Murty @vpmurty.bsky.social · 18/08/2026
New paper linking mesolimbic-hippocampal circuits to childhood trauma and anhedonia with @laurenellman.bsky.social and led by Katey O’Brien. www.jneurosci.org/content/earl...
jneurosci.org
Functional integrity of mesolimbic-hippocampal circuits is associated with anhedonia in individuals with early life stress
Anhedonia reflects a transdiagnostic deficit in a range of processes that impact reward and motivation. While human neuroimaging has mainly focused on striatal-related alterations in anhedonia, animal...
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Deepu Murty @vpmurty.bsky.social · 01/08/2026
First foray into characterizing hippocampal-mesolimbic contributions to substance use. Props to awesome former post-doc Blake Elliott for steering the charge. A few more substance-use related papers are in the pipeline! onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Hippocampus–Ventral Striatum Connectivity Is Associated With Binge Drinking Frequency in Adults
Contextual information, such as spatial locations and social groups, are known to propagate reward-seeking behavior including binge drinking. Animal models suggest that context-evoked drug and alcoho....
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Reposted by Jia-Hou (JH) Poh
Alana Darcher @alanadarcher.bsky.social · 30/07/2026
🎉 *extremely* excited to share our human single neuron + movie dataset is out in #ScientificData! 📄 Human neuron activity during an 83-minute movie from 2,286 neurons and 29 patients 🔗https://www.nature.com/articles/s41597-026-07955-0 1st public dataset from @humansingleneuron.bsky.social!🧵
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Helen Barron @helencbarron.bsky.social · 28/07/2026
***New preprint from the lab*** showing “Generative replay across hippocampal-neocortical circuits”. In sleep we show spiking sequences in V1 (sensory neocortex!) that represent information that has not been directly experienced www.biorxiv.org/content/10.6... @bndu.ox.ac.uk @ndcnoxford.bsky.social
biorxiv.org
Generative replay across hippocampal-neocortical circuits
To make flexible decisions, the brain needs to make inferences between events that were not directly experienced together. In sharp-wave ripple (SWR) events, during periods of rest and sleep, spiking ...
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Rayna Tang @raynatang.bsky.social · 22/07/2026
Excited to share that my first-ever first-author paper (w/ @atabk.bsky.social @AngeliqueDelarazan @zreagh.bsky.social) is now out in PNAS! Building a story to link two objects boosts associative memory and inference, but not memory for the objects themselves. www.pnas.org/doi/10.1073/... 🧵
pnas.org
Active linking through narratives facilitates associative inference | PNAS
In daily life, we often draw inferences about novel associations from prior experiences. This ability, associative inference, is thought to be a ke...
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Moufan Li @moufanli.bsky.social · 20/07/2026
Our paper is out in @natmachintell.nature.com! We trained multiple RNNs to perform free recall. The best-performing ones learned a strategy akin to the memory palace technique. See thread below for more info. www.nature.com/articles/s42...
nature.com
A neural network model of free recall learns multiple memory strategies - Nature Machine Intelligence
Li et al. show that recurrent neural networks optimized for free recall discover diverse, human-like memory strategies beyond classical temporal context models, with top models using an index-based me...
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Tobias Egner @tobiasegner.bsky.social · 15/07/2026
New paper out: Led by super grad student Jim Zhang and in collaboration with Greg Cogan, we review and synthesize Insights into the neural mechanisms supporting cognitive stability and flexibility from human intracranial electroencephalography. For free access: authors.elsevier.com/a/1nRYWY3M3p...
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Allie Sinclair @asinclair.bsky.social · 14/07/2026
Interested in memory updating, exploration, structure learning, & reward? @hannahtarder-stoll.bsky.social & I are looking for candidates to apply for a Connected Minds Postdoctoral Fellowship at York University, with the opportunity to work at Rice too. Contact Hannah or me for details! #PsychJobs
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Elizabeth Goldfarb @evgoldfarb.bsky.social · 10/07/2026
How does stress change the hippocampus to prioritize predictions? Excited to be part of this terrific theme issue, sharing work led by @zhoui.bsky.social, continuing our collab w Nick Turk-Browne and @brynnsherman.bsky.social
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Thomas Yeo @bttyeo.bsky.social · 08/07/2026
A video of a patient who responded well to personalized TMS: www.temasekreview.com.sg/community-st...
temasekreview.com.sg
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Ben Hayden @benhayden.bsky.social · 24/06/2026
New lab paper ! "Shared neural geometries for bilingual semantic representations in human hippocampal neurons" led by @xinyuanyan.bsky.social. 🧵 www.sciencedirect.com/science/arti...
sciencedirect.com
Shared neural geometries for bilingual semantic representations in human hippocampal neurons
The human brain has the remarkable ability to comprehend and express similar concepts in multiple languages. To understand how it does so, we examined…
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Matthias Nau @matthiasnau.bsky.social · 15/06/2026
The massive 7T-fMRI Natural Scenes Dataset (NSD) has been extended to Neuropixels recordings in macaques! Exciting resource for inter-species comparisons by Li et al. @natneuro.nature.com. www.nature.com/articles/s41... Also nice News & Views by Kay and colleagues! www.nature.com/articles/s41...
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Thomas Yeo @bttyeo.bsky.social · 14/06/2026
Paper is now out in Nature Comms doi.org/10.1038/s414... If you are at @ohbmofficial.bsky.social @ohbmtrainees.bsky.social , come check out our poster about Simpson’s paradox in neurodevelopment. Poster number 998 Monday, June 15 | 14:45-15:45 Tuesday, June 16 | 13:30-14:30
doi.org
Convergent and divergent brain–cognition development in early adolescence - Nature Communications
As children enter adolescence, thinking becomes more abstract, coinciding with large-scale changes in brain network organization. Here, the authors show that stable brain network organization plays a ...
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Nico Dosenbach @ndosenbach.bsky.social · 14/06/2026
We've known that socioeconomics (SES) matters for the 🧠. New & 🤯 is that SES drowns out all other brain associations, incl. IQ. If you train an algorithm to predict IQ from brain data, it's still way better at predicting SES. Science Mag: www.science.org/doi/10.1126/... @smarek0502.bsky.social 👀🧵👇
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Erica Busch @elbusch.bsky.social · 11/06/2026
Our new paper is out this week in Nature Neuroscience! www.nature.com/articles/s41... We built a BCI that works with the brain's natural geometry — and we found that people could learn to play a video game with their brains in <1 hr of training. This efficiency is groundbreaking & here's why:
nature.com
Human learning of noninvasive brain–computer interfaces via manifold geometry - Nature Neuroscience
Busch et al. use nonlinear neural manifolds to help humans gain rapid control over a noninvasive brain–computer interface, allowing them to learn how to play a video game with real-time fMRI neurofeed...
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Kimberly Chiew @kimberlychiew.bsky.social · 09/06/2026
✨ VERY excited to share our new paper led by Holly Bowen (SMU) & former ugrad Kyle Thurmann "Effects of reward anticipation on memory encoding and cognitive control outcomes: A meta-analysis" finally in press @ Neuroscience & Biobehavioral Reviews 💵🧠 www.sciencedirect.com/science/arti... Thread 1/n
sciencedirect.com
Effects of reward anticipation on memory encoding and cognitive control outcomes: A meta-analysis
Extensive evidence suggests that cognitive performance is typically enhanced under increased motivation, often in the form of reward anticipation. Whi…
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Sam Verschooren @samversc.bsky.social · 04/06/2026
🎉New paper out today in Nature Reviews Psychology🎉 with @mjdahl.bsky.social, @mariamaly.bsky.social, and @thiasmittner.bsky.social. We've been working on a unified framework for attentional states and the dynamics of transitions between them. 🧵
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Cheng Xue @cxue.bsky.social · 01/06/2026
Excited to share our new review in Trends in Neuroscience with Gouki Okazawa @gouki-okazawa.bsky.social : "The 'neat' and 'messy' in task-dependent neural geometry and computation" where we reviewed what we know about the 'task-manager' in the brain. A thread 👇
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Philip Sulewski @psulewski.bsky.social · 26/05/2026
Now out in Nature Neuroscience: "Fixation duration on natural scenes is explained by memory encoding not processing demand". www.nature.com/articles/s41... Our eyes don't linger because recognition is hard; they linger to remember. Let me take you on a quick tour. 🧵
nature.com
Fixation duration on natural scenes is explained by memory encoding not processing demand - Nature Neuroscience
By combining magnetoencephalography and eye tracking, this study sheds light on why people fixate on some parts of natural scenes longer than others. Rather than visual complexity, fixation durations ...
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Simon W Davis @woodforbrains.bsky.social · 22/05/2026
Perceptual and conceptual influences on memory judgments New paper in @commspsychol.nature.com by the prolific @rmt93.bsky.social www.nature.com/articles/s44... We tested predictions of the global matching model to quantify the interference associated with perceptual or conceptual lure similarity
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Thomas Yeo @bttyeo.bsky.social · 22/05/2026
Here's bonus slides on cross-validation tests, separate from our preprint. Covering: 1. paired (sign-flip) permutation test 2. label-swap permutation test 3. sample-level vs fold-averaged stats 4. a common misapplication of the corrected t-test 5. three bootstrap variants 1/N
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Rui Xu @rui-xu.bsky.social · 20/05/2026
New preprint as my first post! "Monosynaptic connections link functionally similar regions in human cortex." We use electrical stimulation + fMRI in epilepsy patients to map whole-brain monosynaptic connectivity at 42 cortical sites. doi.org/10.64898/202... 1/n
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Thomas Yeo @bttyeo.bsky.social · 21/05/2026
In a meta-analysis of 210 biomedical AI studies that statistically compared models under cross-validation, 97% used invalid statistical tests. Here's our new preprint doi.org/10.64898/202... led by @tianchu.bsky.social @hetuli.bsky.social @shaoshiz.bsky.social @nichols.bsky.social 1/N
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SJo @sjo09.bsky.social · 13/05/2026
New paper from the lab. Using longitudinal ca imaging, activity-dependent tagging and optogenetics, we show that newly allocated fear engram neurons in amygdala undergo a brief period of coordinated “offline reverberation” immediately after learning. www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Jess Cardin @jess-cardin.bsky.social · 13/05/2026
Do brain circuits really sit in a 'soup' of neuromodulators? Are neurons like soggy bits of bread soaked in signaling factors? Is the whole brain just squelching around in one big pool of warm modulators?
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David Clewett @davidclewett.bsky.social · 08/05/2026
Can you make your life feel “longer” in retrospect? Add a dose of change and novelty in the present to later expand memories of your past. Excited to share our work on how dopamine-related processing bends memory to reflect the passage of distinct events. newsroom.ucla.edu/releases/can...
newsroom.ucla.edu
Can dopamine bend time to shape memory?
The brain may use dopamine to expand time between distinct events, enabling us to remember unique episodes.
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Ben Hayden @benhayden.bsky.social · 06/05/2026
New paper from the lab! "Plasticity and language in the anaesthetized human hippocampus" www.nature.com/articles/s41...
nature.com
Plasticity and language in the anaesthetized human hippocampus - Nature
In the hippocampus, complex processing of sensory stimuli occurs even in the unconscious state.
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Deepu Murty @vpmurty.bsky.social · 01/05/2026
Our first foray into horror movies was recently published. Former grad student David Gregory used them as a means to study temporal memory for threatening events. pubmed.ncbi.nlm.nih.gov/41965942/
pubmed.ncbi.nlm.nih.gov
Arousal and valence differentially shape temporal memory for naturalistic events - PubMed
While emotional arousal and negative valence both alter episodic memory, their contributions to different facets of temporal memory remain unclear. Here, we examined two components of temporal memory ...
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Dan Quintana @dsquintana.bsky.social · 29/04/2026
Selecting an effect size for power analysis is hard. Many researchers fall back on Cohen's thresholds, but they have no empirical basis and vary wildly by field. Our new paper offers a better option: field-specific effect size distributions built from meta-analytic data doi.org/10.3758/s134...
Abstract
Effect sizes are useful for understanding the magnitude of study results and for planning new studies via power analysis.
However, despite their wide usage, effect sizes are often misinterpreted. This is mostly due to an over-reliance on general
effect size benchmarks that were not intended for broad application across diverse research fields. Inaccurate effect size
interpretations can lead to incorrect conclusions about the magnitude of study results and incorrect sample size estimates,
thereby increasing the likelihood of false-positive results. This article introduces the ESDist R package, which is designed
to calculate empirically derived effect-size benchmarks or a range of reliably detectable empirical effect sizes for a specific
research question or field of interest by computing effect size distributions (ESDs). This package can be used on data that
can be easily extracted from pre-existing meta-analyses to help researchers more accurately plan new studies or to better
understand how an individual study might relate to other studies in their field. ESDist includes a set of features that make it
easy to use in a priori power analysis. Moreover, the package includes a feature for estimating effect size benchmarks that
account for publication bias and are weighted by effect sizes' variances, which addresses existing limitations of using ESDs
for study planning or interpretation.
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Evan Gordon @gordonneuro.bsky.social · 22/04/2026
I always assumed that brain function had to line up with cytoarchitectonics. It turns out I was wrong. Human cortex, especially PFC, is tiled by chains of functional patches that subdivide and interlink architectonic areas into parallel processing streams. www.biorxiv.org/content/10.6...
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Agnès Landemard @agnesland.bsky.social · 15/04/2026
How does blood flow relate to brain activity? We discovered that it reflects two neural populations affected oppositely by arousal. Together, they explain neurovascular coupling in all brain regions and brain states! Out today in Nature: rdcu.be/fdC2A @uclbrainscience.bsky.social
The supply of blood to brain tissue is thought to depend on the overall neural activity in that tissue, and this dependence is thought to differ across brain regions and across brain states. However, studies supporting these views have measured neural activity as a bulk quantity and related it to blood supply following disparate events in different regions. Here we measure fluctuations in neuronal activity and blood volume across the mouse brain, and find that their relationship is consistent across brain states and brain regions but differs in two opposing brainwide neural populations. Functional ultrasound imaging (fUSI) revealed that whisking, a marker of arousal, is associated with brainwide fluctuations in blood volume. Simultaneous fUSI and Neuropixels recordings showed that neurons that increase activity with whisking have distinct haemodynamic response functions compared with those that decrease activity. Their summed contributions predicted blood volume across states.Brainwide Neuropixels recordings revealed that these opposing populations coexist in the entire brain. Their differing contributions to blood volume largely explain the apparent differences in blood volume fluctuations across regions. The mouse brain thus contains two neural populations with opposite relations to brain state and distinct relationships to blood supply, which together account for brainwide fluctuations in blood volume.
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Jeremiah Cohen @jeremiahycohen.bsky.social · 13/04/2026
Delighted to share our discoveries about one of the brain's neurotransmitter systems: www.biorxiv.org/content/10.6... Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1
biorxiv.org
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Rachit Dubey @rachitdubey.bsky.social · 07/04/2026
🚨New preprint and our results are rather concerning.. We find the "boiling frog" equivalent of AI use. Using large-scale RCTs, we provide *casual* evidence that AI assistance reduces persistence and hurts independent performance. And these effects emerge after just 10–15 minutes of AI use! 1/
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Constantinople lab @constantinoplelab.bsky.social · 25/03/2026
Thrilled to share our new paper, which shows that the relative timing of cholinergic and dopamine release dynamically gates whether dopamine acts as an RPE for in vivo plasticity and reinforcement learning. www.nature.com/articles/s41...
nature.com
Acetylcholine demixes heterogeneous dopamine signals for learning and moving
Nature Neuroscience - Jang et al. measured dopamine and acetylcholine release in the striatum of rats performing a decision-making task and found that the relative timing of cholinergic and...
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Hayoung Song @hayoungsong.bsky.social · 23/03/2026
Attention fluctuates over time and across contexts—how is this reflected in the brain?🧠 Fitting a dynamical systems model to fMRI data, we show that the geometry of neural dynamics along the attractor landscape reflects changes in attention. Out in @natcomms.nature.com www.nature.com/articles/s41...
nature.com
Geometry of neural dynamics along the cortical attractor landscape reflects changes in attention - Nature Communications
Attention fluctuates over time and across contexts—how is this reflected in the brain? Fitting a dynamical systems model to fMRI data, Song and colleagues show that the geometry of neural dynamics alo...
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Marlene Cohen @marlenecohen.bsky.social · 20/03/2026
So early Alzheimer’s is characterized by a breakdown in coordinated neuronal activity, expressed behaviorally as disorganization rather than failure. We think coordination is a scale invariant property that can link molecules, cells, circuits, populations, networks, behavior, and beyond. 10/
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Tobias Egner @tobiasegner.bsky.social · 20/03/2026
New paper out in JEP:General, led by uber-productive grad student Ricardo Morales Torres (@rmt93.bsky.social): We use behavior and RNNs to show that object semantics protect visual WM against visual interference but increase susceptibility to semantic interference. psycnet.apa.org/record/2027-...
psycnet.apa.org
APA PsycNet
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Tobias Egner @tobiasegner.bsky.social · 18/03/2026
New review/theory paper out with Julie Bugg, Chris Nuno, and Changrun Huang. The upshot is that we don’t know for certain why it’s so hard to get people to engage proactive control from trial to trial (but it’s fun to think about it and speculate!).
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Emily Finn @esfinn.bsky.social · 16/03/2026
Very happy that this paper from our lab is now out in @pnas.org! What happens when the *same* person experiences the *same* information with a *different* interpretation? Nearly the whole 🧠—well, at least nearly all association cortex—changes how it represents that information! tinyurl.com/p8chj2j7
tinyurl.com
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Roselyne Chauvin @roselynechauvin.bsky.social · 13/03/2026
The 6x US memory champion – Nelson Dellis – can memorize a deck of cards in 40 seconds and knows the first 10K digits of pi. To figure out how, he let us peak inside his brain. Here is what we learned in our precision brain mapping study www.biorxiv.org/content/10.6... youtube.com/shorts/MryMq...
youtube.com
how does his brain do it ? #neuroscience #memory #sport Nelson Dellis 6x US memory champion
YouTube video by Roselyne Chauvin
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Lauren Atlas @laurenatlas.bsky.social · 11/03/2026
NIH is requesting comments on a new draft policy that may require human brain imaging data (and other data) from nih-funded research to only be shared via controlled access, & only with certain countries. I suggest neuroimagers read closely & submit comments by 3/18. osp.od.nih.gov/comment-form...
osp.od.nih.gov
Comment Form: Draft NIH Controlled-Access Data Policy and Proposed Revisions to NIH Genomic Data Sharing Policy
National Institutes of Health (NIH) Office of Science Policy (OSP): Request for Information on Draft NIH Controlled-Access Data Policy and Proposed Revisions to NIH Genomic Data Sharing Policy
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Kimberly Chiew @kimberlychiew.bsky.social · 28/02/2026
Final version now in press at Cognitive, Affective & Behavioral Neuroscience! Congratulations to Rachel for her hard work on this ☺️🧠⚡ trebuchet.public.springernature.app/get_content/...
trebuchet.public.springernature.app
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Tobias Egner @tobiasegner.bsky.social · 24/02/2026
New paper from the lab now out online! @changrun-huang.bsky.social asked whether people use informative pre-cues to up-regulate cognitive control in the spatial Stroop task. Surprisingly, they do not, and we rule out some possible reasons why. Enjoy!
psycnet.apa.org
APA PsycNet
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Nanthia Suthana @suthanalab.bsky.social · 16/02/2026
The biggest problem holding neuroscience back right now isn’t data or tools, thanks in large part to the BRAIN Initiative. It’s fragmentation across species. I wrote this to hopefully spark discussion around an issue that can only be solved as a community👇 www.thetransmitter.org/animal-model...
thetransmitter.org
Neuroscience has a species problem
If neuroscience is serious about building general principles of brain function, cross-species dialogue must become a core organizing principle.
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