iiinova — where your digital self keeps evolving

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 14/10/2026

Deadline for abstract submission for #SACB2027 is this Friday Oct 16 2026! Don't miss the chance to present your cancer systems biology work sacbmeeting.org

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 06/10/2026

The abstract deadline for #SACB2027 is Friday, Oct 16! Join us Jan 20-23 at CU Anschutz (Aurora, CO). Submissions are open for oral & poster presentations, a special session on Spatial Single-Cell Cancer Systems Biology, and our Postdoc Highlight Session! sacbmeeting.org

sacbmeeting.org

Systems Approaches to Cancer Biology · SACB Meeting

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Carl T. Bergstrom @carlbergstrom.com · 11/09/2026

"...solving problems is only a tool and proxy for achieving the primary goal of conceptual understanding and insight. Forgetting this in the world of AI may turn the tool against the primary goal."

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Terence Tao @teorth.bsky.social · 11/09/2026

A group of 25 Fields Medalists, including myself, have made a joint declaration on Math and AI: mathandai.org . We welcome additional signatories. See also this article in the Economist announcing the declaration: www.economist.com/science-and-...

mathandai.org

Declaration — Math and AI

Read the declaration and add your name.

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Jorge Gómez Tejeda Zañudo @jgtzanudo.bsky.social · 16/04/2026

Full poster and session details: Title: MBCproject: multi-omic profiling of metastatic breast cancer evolution through patient-partnered research Session: PO.MCB08.05 When: Wednesday April 22 2026, 9 AM - 12 PM Location: Poster Number 7265, Section 21, Board Number 5

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Jorge Gómez Tejeda Zañudo @jgtzanudo.bsky.social · 16/04/2026

... (3) TBX3 mutations are enriched in MBC and co-occur with ERBB2 mutations in ILC and IDC histologies. Expect more to come from this work!

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Jorge Gómez Tejeda Zañudo @jgtzanudo.bsky.social · 16/04/2026

Our main results are that (1) key driver mutations that are commonly considered truncal (PIK3CA and CDH1) exhibit complex clonal dynamics in paired biopsies, (2) bilateral biopsies from MBC patients were phylogenetically unrelated but had shared driver mutations and CNVs, and (3) ...

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Jorge Gómez Tejeda Zañudo @jgtzanudo.bsky.social · 16/04/2026

The Metastatic Breast Cancer project (MBCproject) is a patient-partnered study from the Count Me In initiative at @broadinstitute.org. Thanks to all the patients that made this work possible! #MBC #MetastaticBreastCancer #BreastCancer

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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 23/10/2025

@joann-trejo.bsky.social, @marymunson4.bsky.social and I have a commentary in @natcellbio.nature.com on recent attacks on DEI in biomedical research: "If scientific research, especially biomedical research, is meant to serve everyone, then it requires that everyone has an opportunity to participate"

nature.com

Scaling back DEI programmes and the loss of scientific talent

Nature Cell Biology - Programmes that support diversity, equity and inclusion (DEI) in science are under attack in the USA. Data indicate that diversity in the scientific workforce increases...

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 12/02/2025

Closing comments from @mathcancer.bsky.social at #sacb2025: systems approaches to the study of cell metabolism, cell-cell interactions and spatial relationships will fuel the next findings in cancer treatment

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 12/02/2025

The signal transduction session at #SACB2025 continues with Varuna Nangia discussing how to use cell cycle to study drug effects in melanoma

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 12/02/2025

Last in the signal transduction session at #sacb2025 is Todd Stukenberg from UVA

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 12/02/2025

The #sacb2025 closing keynote is given by Melissa Kemp discussing the role of metabolism and metabolic modeling in cancer

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 12/02/2025

For our last day of #SACB2025 @gottschalklab.bsky.social presents her labs work on macrophage signaling

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 12/02/2025

We’re very excited to hear @theleelab.bsky.social present on modeling cell death in cancer #SACB2025

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 12/02/2025

To kickoff our special session on Health Equity for AI in Cancer we have Dr. Tina Hernandez-Boussard #SACB2025

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 12/02/2025

For our second speaker on our special AI/Equity/Cancer session, we have Dr. Curtis Henry #SACB2025

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 11/02/2025

Day two of #sacb2025 kicks off with Paolo Provenzano from University of Minnesota discussing the immune response in pancreatic cancer

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 11/02/2025

Melissa Davis from Morehouse School of Medicine discusses cancer disparities at #SACB2025

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 11/02/2025

The #SACB2025 immunology session closes out with @davidesanin.bsky.social discussing myeloid cell regulation in prostrate cancer

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 11/02/2025

Last lightning talk session of #SACB2025 with Rebecca Bekker, Lucas Gillenwater, Anisha Datta (1/2)

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 11/02/2025

Systems pharmacology session at #SACB2025 leads off with Marc Birtwistle from Clemson University

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 11/02/2025

Next up at #SACB2025 have @andriy-marusyk.bsky.social discussing the evolutionary dynamics of cancer drug response

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 10/02/2025

Last speaker in our postdoc highlight session is Dr. Wei Hu #SACB2025 on reversible and irreversible resistance mechanisms and personalized treatment

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 11/02/2025

Adriana Del Pino Herrera, one of our SACB Scholars, gives the next lightning talk

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 10/02/2025

Our lightning talks from selected posters starting with Dr. Prasana Vaddi

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 10/02/2025

Dr. Amy Pomeroy is up next in our postdoc spotlight session telling us about their work on mechanistic modeling of combination therapy doi.org/10.1101/2024...

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 10/02/2025

Dr. Christian Meyer on drug combinations, synergy metrics that measure efficacy, and how this can be leveraged for translational work #SACB2025

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 10/02/2025

Now in the postdoc highlight session, Dr. Raghav Jain tells us about their work on AML using multiomics data from CPTAC4

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 10/02/2025

Dr. Cholsoon Jang up next in the metabolism session with a talk on metabolism rewiring in liver cancer and ferroptosis #SACB2025

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 10/02/2025

Cholsoon jang presents on the role of lipid fatty acid length in cancer development #sacb2025

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 10/02/2025

The cancer metabolomics session continues with Bethany Veo #sacb2025

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 10/02/2025

Last speaker for the tumor metabolism session is Yapeng Su from the Fred Hutch #sacb2025

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 10/02/2025

To start our postdoc highlight session, we have Dr. John Metzcar telling us about his work on mechanistic modeling of glioblastoma and its microenvironment #SACB2025

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 10/02/2025

Christine Iacobuzio-Donahue reminding us that even though we know much about the genomic landscape in primary PDAC tumors, there are many gaps in our understanding of its evolution and metastases #SACB2025

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 10/02/2025

At the end of her talk Dr. I-D posted this special call for papers that could benefit the entire #sacb community

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 10/02/2025

Dr. Pamela Becker kicks off the tumor heterogeneity session with her talk on AML drug resistance

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 10/02/2025

Next invited speaker at #sacb2025 is @soledadsosalab.bsky.social discussing cancer cell dissemination and its contribution to tumor dormancy

Big screen with talk title and speaker on the right

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 10/02/2025

Next up at #sacb2025 is Elizabeth Brunk presenting on the use of AI in predicting cancer mutation function

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 10/02/2025

Last speaker in the tumor heterogeneity session at #sacb2025 is Michelle Barbeau studying EMT via proteogenomic approaches

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 10/02/2025

The afternoon session of #sacb2025 on tumor metabolism is kicked off by Sriram Chandrasekaran talking about computational tools to study cancer metabolism

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 10/02/2025

Our meeting chair @mkemp.bsky.social kicks off #sacb2025 here in sunny Denver, Colorado!

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Association for Cancer Systems Biologists @cancersysbio.bsky.social · 06/02/2025

#SACB2025 meeting is happening this coming week Feb 9-12 2025 at U Colorado Anschutz! We have an incredible set of speakers in line. If you can't be there in person, you can join as a virtual attendee and join the live stream of our sessions sacbmeeting.org

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Carl T. Bergstrom @carlbergstrom.com · 04/02/2025

Modern-Day Oracles or Bullshit Machines? Jevin West (@jevinwest.bsky.social) and I have spent the last eight months developing the course on large language models (LLMs) that we think every college freshman needs to take. thebullshitmachines.com

thebullshitmachines.com

INTRODUCTION

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Mark Peifer (He, him) @peiferlabunc.bsky.social · 02/02/2025

We all need to fight back, and legal efforts are key! The reason NSF money is unfrozen is not because someone in the Trump Administration changed their mind or the NSF Director suddenly developed a moral compass--its because of a Federal Restraining Order

MESSAGE to the NSF PI Community,

On Friday, January 31, 2025, a Federal Court issued a Temporary Restraining Order (TRO) directing Federal grant-making agencies, including the National Science Foundation (NSF), to “...not pause, freeze, impede, block, cancel, or terminate... awards and obligations to provide federal financial assistance to the States, and... not impede the States’ access to such awards and obligations, except on the basis of the applicable authorizing statutes, regulations, and terms.” Although the language of the TRO is directed at State institutions, the Department of Justice has determined that it applies to all NSF award recipients. You can review the TRO here.

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