iiinova — where your digital self keeps evolving

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Gina Hinojosa @ginafortexas.bsky.social · 09/10/2026

8 time Texas HS football state champion coach knows what’s at stake this November.

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Ilan Schwartz @germhuntermd.bsky.social · 13/09/2026

Outcomes After Antifungal Discontinuation in Immunocompromised Patients Treated for Histoplasmosis @nicobarrosid.bsky.social Review of 106 IC pts w histoplasmosis. 28 got <12m Rx (median 182d [123, 217]), 78 got >12m (median 453d [374, 690]). Similar outcomes academic.oup.com/ofid/advance...

KM survival curves comparing treatment duration groups (<12m and >=12m) in histoplasmosis related survival and all cause survival. The lines overlap

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Joaquin Castro @joaquincastrotx.bsky.social · 04/05/2026

ICE arrested a 5th and 2nd grader at the school bus stop in San Antonio as their classmates watched in horror. Their stepmother was detained with them. The community at Alamo Heights Independent School District elementary is speaking out—no child should be locked away at the Dilley trailer prison.

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Eurofins Viracor @eurofinsviracor.bsky.social · 14/04/2026

Today is #WorldChagasDiseaseDay. (April 14th) Recognizing the importance of awareness, vigilance, & diagnostic excellence in caring for vulnerable patients, Our Chagas (T. cruzi) qPCR assay is designed to deliver faster-than-industry standard turnaround times—helping clinicians act sooner. READ 👇

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Garrett M. Graff @vermontgmg.bsky.social · 03/03/2026

When we talk about Baby Boomers not getting off the stage: In 1997, the US president was born in 1946. In 2007, the US president was born in 1946. In 2017, the US president was born in 1946. And next year in 2027? The US president will have been born in 1946.

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Open Forum Infectious Diseases @ofidjournal.bsky.social · 24/02/2026

Emergence of dalbavancin, vancomycin, and daptomycin cross-resistance in MRSA during long-term LVAD suppression with vancomycin followed by dalbavancin: genomic insights and synergy with cefadroxil ✅ Just Accepted 🔗 bit.ly/4azpqPJ

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Jonathan Ryder, MD @jonathanrydermd.bsky.social · 23/02/2026

Is one dose of PenG or 28-days doxycycline adequate for late/unknown syphilis? This study is encouraging! @drmichaelmarks.bsky.social

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Carl Quintanilla @carlquintanilla.bsky.social · 10/01/2026

Health-care. It’s now supporting both GDP consumption AND the job market. 👀

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Ilan Schwartz @germhuntermd.bsky.social · 06/12/2025

Human-to-Human Rabies Transmission via Solid Organ Transplantation from a Donor with Undiagnosed Rabies — United States, October 2024–February 2025 MMWR A man died of donor-derived rabies after receiving a kidney transplant from a donor scratched by a skunk. www.cdc.gov/mmwr/volumes... #TxID

cdc.gov

Human-to-Human Rabies Transmission via Solid Organ...

This report describes the public health response to a patient who died after transplantation with an organ from a donor with undiagnosed rabies.

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Eric Topol @erictopol.bsky.social · 02/10/2025

The role of perturbation of our circadian clock plays in promoting the fibrosis (scarring) of organs www.jci.org/articles/vie...

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Ilan Schwartz @germhuntermd.bsky.social · 25/09/2025

Donor-derived infections with Rickettsia typhi (agent of murine typhus) in 2 kidney transplant recipients (1 fatal) Teaching points - 🐭 typhus transmitted by fleas (& transplant) - Cases 📈 in Texas - Death of diffuse 🫁 , 🧠 edema w/o dx=👎 tx - cfDNA MGS (Karius) can dx wwwnc.cdc.gov/eid/article/...

Figure 1. Timeline describing the transmission of Rickettsia typhi from an organ donor to 2 kidney transplant recipients, Texas, 2024. Day 1 of donor hospitalization is represented as −5, the day of death as −1, and the day of transplantation as 0, after which posttransplant days are listed, ending with the discharge of recipient 1 from the hospital on posttransplant day 20.

Figure 2. Chest radiographs from an organ donor with murine typhus, from a study describing the transmission of Rickettsia typhi from an organ donor to 2 kidney transplant recipients, Texas, 2024. A) Chest radiograph obtained at hospital admission, 5 days after symptom onset, with no specific abnormalities noted. B) Chest radiograph obtained on hospital day 3, revealing extensive alveolar opacities predominantly in the middle and lower lung fields.

Figure 3. Histopathological and immunohistochemical features of formalin-fixed, paraffin-embedded biopsy specimens collected from the right and left kidney allografts procured from a donor who died of murine typhus, from a study describing the transmission of Rickettsia typhi from an organ donor to 2 kidney transplant recipients, Texas, 2024. A) When stained with hematoxylin and eosin, both allografts showed multifocal, interstitial, and predominantly mononuclear peritubular infiltrates, associated with focal endarteritis (thin arrows), features of acute tubular injury, including epithelial attenuation with loss of apical cytoplasm (thin arrowheads), and pigmented casts (large arrow). B) Glomeruli displayed moderate mesangial hypercellularity and tuft adhesions to the Bowman’s capsules (arrows) and intracapillary and mesangial phagocytic foam-cells (arrowheads), That finding is compatible with focal segmental glomerulosclerosis. C) Short chains comprising small, rod-shaped bacteria were revealed in glomerular capillaries by the Warthin–Starry silver impregnation staining technique. Immunoreactive R. typhi antigens were noted within intracellular bacteria in endothelial cells of renal arterioles. D–F) An immunohistochemical stain for typhus-group rickettsiae revealed intact bacteria within endothelial cells of inflamed small vessels and vascular spaces of mesangial capillaries (arrows) and phagocytized bacterial antigens in the cytoplasm of glomerular foam-cells (arrows). Original magnifications ×400 (A, B and E) and ×1,000 (C, D, and F).

Figure 4. Annual case counts of murine typhus in Texas, USA, during 1920–2024. Cases increased from close to zero to ~ 500 in 1930s before spiking to ~2000 in 1940s, then back down close to zero by 1950s, and remained near zero until started creeping back up in 2000s, steadily increasing, now with ~800 cases/year

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John Ganz @lioneltrolling.bsky.social · 18/09/2025

"Politics is not the nursery." www.unpopularfront.news/p/this-is-it

unpopularfront.news

This Is It

Obedience and Support are the Same

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Texas Public Radio @texaspublicradio.bsky.social · 11/09/2025

Once almost eradicated from Texas, flea borne typhus is making a comeback in the United States. Texas has one of the highest rates of typhus in the country. Read More👉 www.tpr.org/bioscience-medi...

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Paul Sax @paulsaxmd.bsky.social · 30/08/2025

For us ID doctors, the CDC has been a rock. Data, guidelines, surveillance, travel advice -- all there, vetted by experts, referenced, reliable. Perfect? No. But watching its dismantling now breaks my heart. Some thoughts: blogs.jwatch.org/hiv-id-obser...

blogs.jwatch.org

Watching the Chaos at the CDC -- with Sadness and Alarm

Throughout my career as an infectious diseases doctor, the CDC has been a rock-solid source. Need reliable data on an outbreak? The CDC. Need thoughtful, evidence-based guidelines? The CDC. Need an au...

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Dare Obasanjo @carnage4life.bsky.social · 20/08/2025

MIT’s NANDA initiative found that 95% of generative AI deployments fail after interviewing 150 execs, surveying 350 workers, and analyzing 300 projects. The real “productivity gains” seem to come from layoffs and squeezing more work from fewer people not AI.

fortune.com

MIT report: 95% of generative AI pilots at companies are failing

There’s a stark difference in success rates between companies that purchase AI tools from vendors and those that build them internally.

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Kara Jorgensen @authorkaraj.bsky.social · 06/08/2025

RFK Jr. backs down all the time when he gets push back, so if anyone wants to call, here's the HHS number 1-877-696-6775. I'd also call your senators/reps as well.

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Jake Scott, MD @jakescottmd.bsky.social · 05/08/2025

JUST IN: HHS shuts down BARDA mRNA vaccine program Scrapping the fastest platform we have is a reckless move rooted in a fundamental misunderstanding of vaccinology. No respiratory vaccine blocks all infections. mRNA vaccines have saved millions of lives. www.hhs.gov/press-room/h...

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The New York Times @nytimes.com · 27/02/2025

For decades, fairness has been the guiding principle of the American organ transplant system. But today, nearly 20% of the time, officials ignore strict rules meant to ensure that donated organs are offered to the patients who need them most, a New York Times investigation found. nyti.ms/3XlqVK1

Marcus Edsall-Parr is pictured in the hospital as he gets dialysis treatments. He is using his iPad and wearing headphones. Text reads: "Organ Transplant System 'In Chaos' as Waiting Lists Are Ignored" Photo by Alyssa Schukar for The New York Times

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Adam Serwer @adamserwer.bsky.social · 26/02/2025

Striking how easily you can get millions of people to vote for a boot on their own face just by lying to them about the boot going on someone else's face.

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dave @gloomfather.bsky.social · 06/02/2025

Hey man sorry to hear about all your political turmoil. Would it help if I scrolled around on the computer all day and drove myself insane?

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Jim Bear @coronin.bsky.social · 05/02/2025

This is, by far, the best and most complete description of what is currently happening to biomedical research in the United States. Derek Lowe normally writes an incredibly level-headed column on drug discovery in academia and the private sector. www.science.org/content/blog...

science.org

Revised and Extended: What's Happening Inside the NIH and NSF

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Jesse D. Jenkins @jessedjenkins.com · 31/01/2025

Everyone seems to be framing Trump's freeze on federal grants as a Constitutional fight over powers of the purse & whether presidents can disregard Congressional appropriations. It is that. But also at stake is the fundamental validity of government contracts! I see much less discussion on this... 🧵

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Rupesh @roqqet.bsky.social · 31/01/2025

Love that it’s normal to analyze our president like he’s a raccoon

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Luke O'Neil @lukeoneil47.bsky.social · 13/01/2025

Had never seen this before I'm crying. How does it just keep getting worse. Bro cooking nothing. www.youtube.com/watch?v=59NV...

youtube.com

RZA unironically creates a terrible beat for a Guitar Center promo

YouTube video by Nicholas Wilson

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David M. Perry @lollardfish.bsky.social · 27/12/2024

Nice story about a great camp near Duluth founded for kids with HIV is for sale. Because there aren't enough kids who need it anymore. www.startribune.com/closure-of-n...

startribune.com

Closure of northern Minnesota camp is ‘the greatest story.’ Here’s why.

Willow River, Minn., camp One Heartland is for sale after serving kids there for nearly three decades.

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Ursula Hofer @hoferu.bsky.social · 20/12/2024

Infectious diseases is not only about the latest trials and big cohort studies. So, here is a list of my favourite pieces that you might missed from The Lancet Infectious Diseases in 2024 that reflect on the field at large, in no specific order. #IDSky

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More Perfect Union @moreperfectunion.bsky.social · 12/12/2024

A bill to break up UnitedHealth, CVS, Cigna and more has been introduced by a bipartisan group of U.S. senators and representatives. The legislation would force insurers to sell their pharmacy businesses. It aims to combat PBMs, pharma middlemen who drive up costs.

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Daniel Martin @fizbin.bsky.social · 22/03/2024

I don't know who needs to know this, but Pro Publica has an online thing that will format a letter to your US health insurance company to demand the records behind a claim denial. (which the insurance is then legally required to provide in most cases) projects.propublica.org/claimfile/

projects.propublica.org

Find Out Why Health Insurance Denied Your Claim

You likely have the right to access records that explain why your insurer denied your claim or prior authorization request. Use ProPublica’s free tool to generate a letter requesting your claim file f...

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