Project Code NMH27Ca Isles Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary By bringing together transcriptomics and cutting edge imaging, and dataan...

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

News will come as a shock to staff, especially at Cranfield, but the institutions’ bosses say intention is growth

Age-related microbiome changes increase medium-chain fatty acid-producing bacteria, driving GPR84-mediated myeloid inflammation, impaired vagal signalling and hippocampal dysfunction; targeting this g...

Muscularis macrophages, housekeepers of enteric nervous system integrity and intestinal homeostasis, modulate α-synuclein pathology and neurodegeneration in models of Parkinson’s disease, and understa...

Intranasal delivery of acyl-ghrelin using gold nanorods (AuNRs) is investigated as a strategy for treating neurodegenerative diseases. Acyl-ghrelin is conjugated to AuNRs under optimized conditions t...

As the UK’s fourth largest export industry, universities are a missed opportunity in the government’s plan

We offer a wide range of funded and fully funded research scholarships in all subject areas. Explore your options and apply now.

The ratio between the levels of two synaptic proteins in cerebrospinal fluid predicts future cognitive resilience versus decline among presymptomatic individuals and individuals with early Alzheimer’s...

A multicenter randomized controlled trial found that incorporating time-restricted eating, regardless of the timing of the eating window, into usual care—combining a Mediterranean diet with a nutritio...

1-3 October 2025. Registrations and abstract submission (short talks and posters) will open on April 15th.

A comprehensive single-cell RNA sequencing study delineates cell-type-specific transcriptomic changes in the brain associated with normal ageing that will inform the investigation into functional chan...

Abstract. Obesity is now considered a chronic relapsing progressive disease, associated with increased all-cause mortality that scales with body weight, af

Yang et al. identify and characterize distinct sugar- and fat-responsive neuronal populations in the dorsal hippocampus and their contribution to the development of obesity.

Multimodal transcriptomics unveil the molecular dynamics of neural stem cells and their surrounding niche in the aging mouse hippocampus and provide a resource to understand age-related molecular chan...

The company found its own toxic compounds in human blood—and kept selling them.

Bayati et al. discovered that sequential treatment of iPSC-derived dopaminergic neurons with α-synuclein fibrils and proinflammatory cytokines leads to the formation of Lewy body–like inclusions, thro...

A team of exceptional researchers are applying free-market principles in their efforts to tackle the devastating disease

Orthogonal murine models demonstrate the bioactivity and neuronal targets of a GLP-1/leptin coagonist in relation to food intake and body weight.

To engineer cells that can specifically target the central nervous system (CNS), we identified extracellular CNS-specific antigens, including components of the CNS extracellular matrix and surface mol...

The in-vitro seeded fibrils are unlikely to be disease-relevant and representative of the diverse alpha-synuclein polymorphs in the brain.

Neurodegenerative disorders represent a leading cause of disability among the elderly population, and Parkinson's disease (PD) is the second most prevalent. Emerging evidence suggests a frequent co-oc...

In a collection of research articles and related content, the Human Cell Atlas consortium presents tools, data and ideas towards the generation of their first draft atlas of cells in the human body.

The R1441C-Lrrk2 mutation causes age-acquired immune exhaustion in mouse macrophages in a sex-dependent manner.

Dr Jeff Davies of Swansea University Medical School has been awarded a prestigious Fulbright All Disciplines Scholar Award, which will enable him to conduct research at the world-renowned neuroscience...