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Endocrine Society Journals

@endosocjournals.bsky.social

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Promoting the essential and integrative role of endocrinology in public health, medical research, and health care delivery through our five publications, thematic issues, and special collections. academic.oup.com/endocrinesociety

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Endocrine Society Journals @endosocjournals.bsky.social · 02/10/2026

Obesity science, research gaps, and opportunities in the new era of obesity medicines: an Endocrine Society scientific statement. Read more in #Endocrine Reviews: bit.ly/46tf4Oq @endocrinesociety.bsky.social

Obesity science, research gaps, and opportunities in the new era of obesity medicines: an Endocrine Society scientific statement

Abstract. The medical management of obesity has been transformed by the introduction of obesity medicines (OMs), based on the actions of glucagon-like pept

Endocrine Society Journals @endosocjournals.bsky.social · 02/10/2026

Genetic factors associated with thymic tumors in patients with MEN1: a nested case-control study in the GTE/AFCE cohort. Read more in #JES: bit.ly/4h2jlhW @endocrinesociety.bsky.social

Genetic factors associated with thymic tumors in patients with MEN1: a nested case-control study in the GTE/AFCE cohort

AbstractContext. Multiple endocrine neoplasia type 1 (MEN1) is a rare autosomal dominant syndrome characterized by tumors in multiple endocrine tissues. It

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Endocrine Society Journals @endosocjournals.bsky.social · 01/10/2026

Steroids, stress, and body mass index interact to accelerate female pubertal development. Read more in #JCEM: bit.ly/4hk0j5x @endocrinesociety.bsky.social

Steroids, stress, and body mass index interact to accelerate female pubertal development

AbstractContext. Estrogens underlie puberty in girls, but the steroid metabolome may also regulate pubertal timing in response to elevated stress and incre

Endocrine Society Journals @endosocjournals.bsky.social · 29/09/2026

ROR1/ROR2 regulate aldosterone production from the zona glomerulosa. Read more in #Endocrinology: bit.ly/3T8hfUA @endocrinesociety.bsky.social

ROR1/ROR2 regulate aldosterone production from the zona glomerulosa

Abstract. Adrenal morphogenesis and aldosterone production depend on tightly regulated signaling pathways. While β-catenin (βCat)-dependent Wnt signaling i

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Endocrine Society Journals @endosocjournals.bsky.social · 28/09/2026

Adrenal rather than central dysfunction limits hypothalamic–pituitary–adrenal axis recovery after chronic glucocorticoid treatment in male mice. Read more in #Endocrinology: bit.ly/3VDpf0p @endocrinesociety.bsky.social

Adrenal rather than central dysfunction limits hypothalamic–pituitary–adrenal axis recovery after chronic glucocorticoid treatment in male mice

Abstract. Glucocorticoid-induced adrenal insufficiency (GIAI) can persist for months after discontinuation of chronic corticosteroid therapy, placing patie

Endocrine Society Journals @endosocjournals.bsky.social · 28/09/2026

What did you think of our Thematic Issue on Nuclear Receptors @endosocjournals.bsky.social? Reread and share our collection of journal articles with curations from #EndocrineReviews, #Endocrinology, #JES, #JCEMCaseReports, and #JCEM: bit.ly/4ACB4nC

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Endocrine Society Journals @endosocjournals.bsky.social · 25/09/2026

Hypothalamic-pituitary deficiency after radiation in childhood cancer survivors is associated with rare variants in TNS2. Read more in #JCEM: bit.ly/4xWYVga @endocrinesociety.bsky.social

Hypothalamic-pituitary deficiency after radiation in childhood cancer survivors is associated with rare variants in TNS2

AbstractContext. Radiation to the hypothalamic-pituitary (HP) region (HP-RT) is a strong risk factor for HP deficiency among childhood cancer survivors (su

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Endocrine Society Journals @endosocjournals.bsky.social · 25/09/2026

Adrenal crises and quality of life after bilateral adrenalectomy vs primary autoimmune adrenal insufficiency. Read more in #JES: bit.ly/4y8GNjy @endocrinesociety.bsky.social

Adrenal crises and quality of life after bilateral adrenalectomy vs primary autoimmune adrenal insufficiency

AbstractContext. Bilateral adrenalectomy (BLA) and autoimmune adrenal insufficiency (AAI) are 2 major causes of primary adrenal insufficiency (PAI). Compar

Endocrine Society Journals @endosocjournals.bsky.social · 24/09/2026

Glucocorticoids in pregnancy: a master-switch for fetal maturation. Read more in #Endocrine Reviews: bit.ly/4AsUf3t @endocrinesociety.bsky.social

Glucocorticoids in pregnancy: a master-switch for fetal maturation

Abstract. The prepartum surge in plasma glucocorticoids is a critical signal for fetal organ maturation, facilitating the transition from fetal reliance on

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Endocrine Society Journals @endosocjournals.bsky.social · 22/09/2026

Prolactin receptor overexpression in pregnancy-associated Cushing syndrome and functional implications. Read more in #JCEM Case Reports: bit.ly/46tfGnc @endocrinesociety.bsky.social

Prolactin receptor overexpression in pregnancy-associated Cushing syndrome and functional implications

Abstract. Cushing syndrome (CS) during pregnancy is rare but is associated with substantial maternal and fetal risks. Although aberrant activation of G pro

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Endocrine Society Journals @endosocjournals.bsky.social · 28/08/2026

Cushing disease and unilateral primary aldosteronism confounded by a nonfunctioning contralateral adrenal incidentaloma. Read more in #JCEM Case Reports: bit.ly/3Syk9l7 #CushingDisease, #PrimaryAldosteronism @endocrinesociety.bsky.social

Cushing disease and unilateral primary aldosteronism confounded by a nonfunctioning contralateral adrenal incidentaloma

Abstract. The discovery of an adrenal incidentaloma should prompt an evaluation for the presence of malignancy and autonomous hormonal secretion. Concomita

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Endocrine Society Journals @endosocjournals.bsky.social · 27/08/2026

Sex hormones and exercise in the musculoskeletal system: from signaling to structure and function. Read more in #Endocrine Reviews: bit.ly/4wy0Bez #CollagenTurnover, #SoftConnectiveTissue @endocrinesociety.bsky.social

Sex hormones and exercise in the musculoskeletal system: from signaling to structure and function

Abstract. Sex steroid hormones, such as estrogen, progesterone, and testosterone, are primarily known as critical regulators of reproductive function in bo

Endocrine Society Journals @endosocjournals.bsky.social · 25/08/2026

Diagnostic utility of basal luteinizing hormone in evaluating central precocious puberty. Read more in #JES: bit.ly/4g2Rs8P #EarlyPuberty, #BasalLuteinizingHormone @endocrinesociety.bsky.social

Diagnostic utility of basal luteinizing hormone in evaluating central precocious puberty

AbstractBackground. Basal luteinizing hormone (bLH) is increasingly proposed as a surrogate marker of hypothalamic–pituitary–gonadal activation, potentiall

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Endocrine Society Journals @endosocjournals.bsky.social · 24/08/2026

Health-related quality of life in children with multiple endocrine neoplasia (MEN) and their siblings. Read more in #JCEM: bit.ly/3TZsezO #MultipleEndocrineNeoplasia, #Psychosocial @endocrinesociety.bsky.social

Health-related quality of life in children with multiple endocrine neoplasia (MEN) and their siblings

AbstractContext. Multiple Endocrine Neoplasia (MEN) syndromes are rare autosomal dominant hereditary tumor predisposition syndromes affecting multiple fami

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Endocrine Society Journals @endosocjournals.bsky.social · 21/08/2026

Examining mechanisms by which acute psychosocial stress disrupts the proestrous LH surge and ovulation in female mice. Read more in #Endocrinology: bit.ly/4iaXvJQ #LuteinizingHormone, #Ovulation @endocrinesociety.bsky.social

Examining mechanisms by which acute psychosocial stress disrupts the proestrous LH surge and ovulation in female mice

Abstract. Stress most often inhibits reproduction. Exposure to an acute layered psychosocial stress paradigm (ALPS) on proestrus disrupts the LH surge in 6

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Endocrine Society Journals @endosocjournals.bsky.social · 21/08/2026

Primary adrenal insufficiency resulting in diagnosis of rare ABCD1 pathogenic variant in X-linked adrenoleukodystrophy. Read more in #JCEM Case Reports: bit.ly/4hDo4qV #AdrenalInsufficiency, #ABCD1 @endocrinesociety.bsky.social

Primary adrenal insufficiency resulting in diagnosis of rare ABCD1 pathogenic variant in X-linked adrenoleukodystrophy

Abstract. X-linked adrenoleukodystrophy (X-ALD) is a rare neurodegenerative demyelinating disorder with variable presentations. We report a case of a 32-ye

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Endocrine Society Journals @endosocjournals.bsky.social · 20/08/2026

Moderate- versus high-activity radioactive iodine in intermediate-risk papillary thyroid cancer: a Canadian cohort study. Read more in #JES: bit.ly/4hDo2zj #PapillaryThyroidCancer, #RadioactiveIodineTherapy @endocrinesociety.bsky.social

Moderate- versus high-activity radioactive iodine in intermediate-risk papillary thyroid cancer: a Canadian cohort study

AbstractContext. The optimal radioactive iodine (RAI) activity for intermediate-risk papillary thyroid cancer (PTC) remains uncertain, and evidence to guid

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Endocrine Society Journals @endosocjournals.bsky.social · 18/08/2026

Genotype-phenotype heterogeneity among patients with lipodystrophy harboring rare POLD1 variants. Read more in #JCEM: bit.ly/45PDPEh #MandibularHypoplasia #deafness @endocrinesociety.bsky.social

Genotype-phenotype heterogeneity among patients with lipodystrophy harboring rare POLD1 variants

AbstractContext. Mandibular hypoplasia, deafness, progeroid features, and lipodystrophy (MDPL) syndrome is a rare, autosomal dominant disorder due to patho

Endocrine Society Journals @endosocjournals.bsky.social · 17/08/2026

Generation and utility of endocrine functional testicular organoids. Read more in #Endocrinology: bit.ly/4xJUapB #testicular #organoid @endocrinesociety.bsky.social

Generation and utility of endocrine functional testicular organoids

Abstract. Male infertility is increasing in prevalence due to cancer treatment, environmental exposures, and patient-specific syndromes. Traditional two-di

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Endocrine Society Journals @endosocjournals.bsky.social · 14/08/2026

Semaglutide use for hypothalamic obesity and type 2 diabetes mellitus after suprasellar germinoma treatment. Read more in #JCEM Case Reports: bit.ly/4gcRIRJ #HypothalamicObesity #Semaglutide @endocrinesociety.bsky.social

Endometriosis-associated pain: mechanism, neuroimmune signature, and translational precision strategies

Abstract. Endometriosis affects approximately 10% of reproductive-aged women worldwide and is a leading cause of chronic pelvic pain. Despite its high prev

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Endocrine Society Journals @endosocjournals.bsky.social · 14/08/2026

Endometriosis-associated pain: mechanism, neuroimmune signature, and translational precision strategies. Read more in #Endocrine Reviews: bit.ly/4gcRIRJ #Endometriosis #Neuroinflammation @endocrinesociety.bsky.social

Endometriosis-associated pain: mechanism, neuroimmune signature, and translational precision strategies

Abstract. Endometriosis affects approximately 10% of reproductive-aged women worldwide and is a leading cause of chronic pelvic pain. Despite its high prev

Endocrine Society Journals @endosocjournals.bsky.social · 12/08/2026

The impact of statins on aldosterone production in healthy adults: a randomized controlled study. Read more in #JES: bit.ly/4wEEyUz #Aldosterone #Hyperlipidemia @endocrinesociety.bsky.social

The impact of statins on aldosterone production in healthy adults: a randomized controlled study

AbstractBackground. Statins lower atherosclerotic cholesterol, but the cardiovascular benefit from treatment may extend beyond lipid management. Our group

Endocrine Society Journals @endosocjournals.bsky.social · 11/08/2026

Ovarian reserve and endothelial health in healthy reproductive-age women. Read more in #JCEM: bit.ly/3S81mgg #OvarianAging #EndothelialFunction @endocrinesociety.bsky.social

Ovarian reserve and endothelial health in healthy reproductive-age women

AbstractContext. While the literature suggests women with diminished ovarian reserve may have increased metabolic risk, implications for long-term health a

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Endocrine Society Journals @endosocjournals.bsky.social · 10/08/2026

3D genome architecture and epigenetic regulation of lineage identity in advanced prostate cancer. Read more in #Endocrinology: bit.ly/4pWziZV #ProstateCancer #LineagePlasticity @endocrinesociety.bsky.social

3D genome architecture and epigenetic regulation of lineage identity in advanced prostate cancer

Abstract. Prostate cancer development and progression depend on androgen receptor (AR) signaling. Therefore, androgen-deprivation therapy (ADT) and AR sign

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Endocrine Society Journals @endosocjournals.bsky.social · 07/08/2026

Semaglutide-associated Twiddler syndrome. Read more in #JCEMCaseReports: bit.ly/44BZoHL #GLP1Agonists #TwindlerSyndrome @endocrinesociety.bsky.social

Endocrine Society Journals @endosocjournals.bsky.social · 06/08/2026

Growth hormone retesting for idiopathic isolated growth hormone deficiency during and after puberty: a systematic review. Read more in #JES: bit.ly/4wSI9hh #PituitaryDwarfism #HumanGrowthHormone #GonadalSteroidHormones @endocrinesociety.bsky.social

Growth hormone retesting for idiopathic isolated growth hormone deficiency during and after puberty: a systematic review

AbstractContext. Idiopathic isolated growth hormone deficiency (IIGHD) is difficult to diagnose due to the day-to-day variation in growth hormone (GH) secr

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Endocrine Society Journals @endosocjournals.bsky.social · 05/08/2026

Weight loss reduces intermuscular adipose tissue and liver fat compared to exercise: implications for muscle quality and metabolic health. Read more in #JCEM: bit.ly/4fNM3lK #IntermuscularAdiposeTissue #Lipidomics #obesity @endocrinesociety.bsky.social

Endocrine Society Journals @endosocjournals.bsky.social · 04/08/2026

Testosterone protects from metabolic syndrome-associated lung dysfunction in a high-fat diet rabbit model. Read more in #Endocrinology: bit.ly/4wNAIb8 #MetabolicSyndrome #HighFatDiet @endocrinesociety.bsky.social

Endocrine Society Journals @endosocjournals.bsky.social · 03/08/2026

Development of Graves orbitopathy after thyroidectomy for thyroid cancer. Read more in #JCEM Case Reports: bit.ly/4feP4eL #GravesDisease #GravesOrbitopathy @endocrinesociety.bsky.social

Development of Graves orbitopathy after thyroidectomy for thyroid cancer

Abstract. We present a case of a 76-year-old female with a history of papillary thyroid cancer treated with a total thyroidectomy, central neck dissection,

Endocrine Society Journals @endosocjournals.bsky.social · 31/07/2026

Epigenetics and childhood obesity: DNA methylation coordinates environment and gene regulation. Read more in #EndocrineReviews: bit.ly/4wffPWz #ChildhoodObesity #EpigeneticRegulation @endocrinesociety.bsky.social

Endocrine Society Journals @endosocjournals.bsky.social · 30/07/2026

Psychiatric morbidity following liothyronine exposure in autoimmune hypothyroidism: a Swedish nationwide cohort study. Read more in #JES: bit.ly/4yzkGU3 #LT3 #HashimotoThyroiditis @endocrinesociety.bsky.social

Psychiatric morbidity following liothyronine exposure in autoimmune hypothyroidism: a Swedish nationwide cohort study

AbstractContext. Levothyroxine (LT4) is the primary treatment of hypothyroidism. Despite adequate LT4 substitution some patients experience symptoms and th

Endocrine Society Journals @endosocjournals.bsky.social · 29/07/2026

Utility of genomic sequencing classifier in managing cytologically indeterminate oncocytic thyroid nodules. Read more in #JCEM: bit.ly/4hoXRfA #ThyroidNodule #IndeterminateCytology @endocrinesociety.bsky.social

Utility of genomic sequencing classifier in managing cytologically indeterminate oncocytic thyroid nodules

AbstractContext. Oncocytic cells can occur in benign and malignant thyroid nodules, posing a diagnostic challenge. This has reduced the diagnostic performa

Endocrine Society Journals @endosocjournals.bsky.social · 28/07/2026

Kisspeptin made in the preoptic area is required for normal estradiol-induced LH surges and optimal fertility in females. Read more in #Endocrinology: bit.ly/4b6hiGa #LHSurge #Kisspeptin #GnRH @endocrinesociety.bsky.social

Kisspeptin made in the preoptic area is required for normal estradiol-induced LH surges and optimal fertility in females

Abstract. Ovulation is triggered by a surge in luteinizing hormone (LH) secretion from the pituitary. The LH surge is itself driven by a surge in gonadotro

Endocrine Society Journals @endosocjournals.bsky.social · 27/07/2026

Tirzepatide-associated interstitial kidney injury. Read more in #JCEM Case Reports: bit.ly/4yyFlaO #Tirzepatide #DrugInducedKidneyInjury @endocrinesociety.bsky.social

Endocrine Society Journals @endosocjournals.bsky.social · 24/07/2026

Relationship between histopathological findings and RAI in non-papillary follicular cell–derived thyroid carcinoma. Read more in #JES: bit.ly/4fsVKFa #DifferentiatedHighGradeThyroidCarcinoma #FollicularThyroidCarcinoma @endocrinesociety.bsky.social

Endocrine Society Journals @endosocjournals.bsky.social · 23/07/2026

Integrative genetic and liver transcriptomic analyses identify TRIB1AL as a target for steatotic liver disease. Read more in #JCEM: bit.ly/45gJMti #TRIB1AL #LiverProtemics @endocrinesociety.bsky.social

Endocrine Society Journals @endosocjournals.bsky.social · 22/07/2026

Mineralocorticoid and glucocorticoid receptor cooperation drives advanced phenotypes in triple-negative breast cancer. Read more in #Endocrinology: bit.ly/4b6V0nL #TripleNegativeBreastCancer #MineralcoticoidReceptorNR3C2Gene @endocrinesociety.bsky.social

Mineralocorticoid and glucocorticoid receptor cooperation drives advanced phenotypes in triple-negative breast cancer

Abstract. Oncogenic cell signaling, including the activation of cellular stress or cytokine-induced pathways, is a hallmark of cancer. In triple-negative b

Endocrine Society Journals @endosocjournals.bsky.social · 21/07/2026

Perinatal organophosphate flame-retardant exposure alters adult stress axis and avoidance behavior in mice. Read more in #Endocrinology: bit.ly/3RbBHTp #FlameRetardants #EndocrineDisruption #HPAAxis @endocrinesociety.bsky.social

Endocrine Society Journals @endosocjournals.bsky.social · 20/07/2026

Mkrn3, Dlk1, and Mecp2 have distinct hypothalamic expression patterns across pubertal maturation in male and female mice. Read more in #JES: bit.ly/4wizTqC #puberty #hypothalamus @endocrinesociety.bsky.social

Mkrn3, Dlk1, and Mecp2 have distinct hypothalamic expression patterns across pubertal maturation in male and female mice

Abstract. Pubertal onset is driven by the reactivation of the hypothalamic-pituitary-gonadal (HPG) axis, a process orchestrated by a complex interplay of s

Endocrine Society Journals @endosocjournals.bsky.social · 17/07/2026

Acromegaly and cardiovascular disease: mechanisms, clinical impact, and evolving management. Read more in #EndocrineReviews: bit.ly/4oV9ug1 #acromegaly #GrowthHormoneResponse @endocrinesociety.bsky.social

Acromegaly and cardiovascular disease: mechanisms, clinical impact, and evolving management

Abstract. Cardiovascular disease is one of the most common and serious complications of acromegaly and a leading contributor to reduced life expectancy in

Endocrine Society Journals @endosocjournals.bsky.social · 16/07/2026

Unexpected resolution of chronic gastroesophageal reflux disease with testosterone replacement therapy. Read more in #JCEM Case Reports: bit.ly/4v3vjLI #GastroesophagealRefluxDisease #hypogonadism @endocrinesociety.bsky.social

Unexpected resolution of chronic gastroesophageal reflux disease with testosterone replacement therapy

Abstract. A 63-year-old man with a chronic, 30-year, history of gastroesophageal reflux disease (GERD) that required long-term proton pump inhibitor (PPI)

Endocrine Society Journals @endosocjournals.bsky.social · 15/07/2026

Melatonin improves postprandial hypoglycemia: an unusual presentation of insulinoma. Read more in #JCEM Case Reports: bit.ly/4algJYJ #insulinoma #melatonin @endocrinesociety.bsky.social

Melatonin improves postprandial hypoglycemia: an unusual presentation of insulinoma

Abstract. Insulinoma is the most prevalent neuroendocrine tumor of the pancreas, presenting with a spectrum of neuroglycopenic symptoms. This case report d

Endocrine Society Journals @endosocjournals.bsky.social · 14/07/2026

Effects of saccharin on insulin sensitivity in adult, overweight individuals without diabetes: a real-world pilot study. Read more in #JES: bit.ly/4wbxEWb #saccharin #InsulinResistance #Overweight @endocrinesociety.bsky.social

Effects of saccharin on insulin sensitivity in adult, overweight individuals without diabetes: a real-world pilot study

AbstractContext. It has been suggested that consumption of saccharin, a widely used artificial sweetener, decreases insulin sensitivity in rodents and huma

Endocrine Society Journals @endosocjournals.bsky.social · 13/07/2026

Hyperthyroidism and Birth Defects: The Roles of Maternal Thyroid Function and Thyroid Autoantibody Positivity. Read more in #JCEM: bit.ly/4vvGcY3 #malformations #carbimazole #propylthiouracil @endocrinesociety.bsky.social

Endocrine Society Journals @endosocjournals.bsky.social · 10/07/2026

NR3C1 is required for normal somatotrope differentiation and Foxo1 expression in pituitary. Read more in #Endocrinology: bit.ly/4uQfkkl #Glucocorticoids #NR3C1 #somatotrope @endocrinesociety.bsky.social

NR3C1 is required for normal somatotrope differentiation and Foxo1 expression in pituitary

Abstract. Glucocorticoids are an important signal for the differentiation of many types of cells. Consistent with this, several studies have demonstrated t

Endocrine Society Journals @endosocjournals.bsky.social · 09/07/2026

Ultra-rapid prolactin normalization with cabergoline in a premenopausal woman with epilepsy and giant prolactinoma. Read more in #JCEMCaseReports: bit.ly/4afcMVs #Cabergoline #epilepsy #GiantProlactinoma @endocrinesociety.bsky.social

Endocrine Society Journals @endosocjournals.bsky.social · 08/07/2026

Glycated CD59, a Novel Biomarker for Gestational Diabetes. Read more in #EndocrineReviews: bit.ly/3QqbEYl #GestationalDiabetesMellitus #GlycatedCD59 #biomarker @endocrinesociety.bsky.social

Endocrine Society Journals @endosocjournals.bsky.social · 07/07/2026

Potential risk of neoplasms with fezolinetant: clinical evidence, mechanisms, and post-marketing implications. Read more in #JES: bit.ly/4acRKqx #Fezolinetant #menopause #neoplasms @endocrinesociety.bsky.social

Endocrine Society Journals @endosocjournals.bsky.social · 06/07/2026

Bone turnover in arginine vasopressin deficiency: a comparative study with primary polydipsia and healthy controls. Read more in #JCEM: bit.ly/4vp8PGf #ArginineVasopressinDeficiency #PrimaryPolydipsia #BoneTurnoverMarkers @endocrinesociety.bsky.social

Endocrine Society Journals @endosocjournals.bsky.social · 03/07/2026

Generation of a prop1 knockin zebrafish enables single-cell transcriptomics of early pituitary development. Read more in #Endocrinology: bit.ly/4oFnGtl #EarlyPituitaryDevelopment #zebrafish #SingleCellTranscriptomics @endocrinesociety.bsky.social