iiinova — where your digital self keeps evolving

Reposted by Jürg Bähler

Snezhka Oliferenko @alebenoit.bsky.social · 02/10/2026

Guys! @jbahler.bsky.social and I are recruiting a PhD student in this round - if you know great undergrads or Masters students please tell them about us! And Crick in general, of course ;) Thank you!!

079

Reposted by Jürg Bähler

Tomáš Pluskal @pluskal-lab.org · 26/06/2026

Do you have a bold, daring vision how to transform research in biology? Are you a young scientist within 7 years since your PhD? Submit your idea by July 31 to the Dream Biology Award competition and you can win the first prize of €10,000! More details at dreambiologyaward.org

087

Reposted by Jürg Bähler

Ben Heineike @heineikeb.bsky.social · 18/03/2026

This project from @jbahler.bsky.social lab at @ucl.ac.uk's Genetics Evolution and Environment (GEE) department came out of a summer project from Celeste Cohen and a very productive masters project from first author @bencekover.bsky.social.

121

Reposted by Jürg Bähler

Manuel Lera-Ramirez @manu-lera.bsky.social · 23/02/2026

Someone requested #GoldenBraid Assembly, now it's live on #OpenCloning. Still missing the omega Level 1 assembly (coming very soon). For GoldenBraid reference: goldenbraidpro.com and pmc.ncbi.nlm.nih.gov/articles/PMC...

0101

Jürg Bähler @jbahler.bsky.social · 23/02/2026

#OpenCloning is shaping up to be a really useful tool, and the new Assembler is powerful for defining and using Golden Gate syntaxes. Give it a try!

041

Reposted by Jürg Bähler

Manuel Lera-Ramirez @manu-lera.bsky.social · 11/02/2026

🚀 Update from @pombase.bsky.social! Gene pages now link to OpenCloning. Load the gene region instantly and design primers + cloning strategies in one click 🧬🧪✨ To get started with OpenCloning, check the docs: docs.opencloning.org

Pombase gene page with an arrow pointing at the link to OpenCloning

053

Reposted by Jürg Bähler

PomBase: The S. pombe knowledgebase @pombase.bsky.social · 31/07/2025

PomBase introduces two new interactive views for GO-CAM pathway models: Summary Maps (high-level, visual overview) and Mega-Models (connected models). Check them out here: lnkd.in/gfxNRdua

183

Reposted by Jürg Bähler

Laura Haynes👩‍🔬⚾️🐾💙 @drlaurahaynes.bsky.social · 31/07/2025

Well this is interesting: Psilocybin treatment extends cellular lifespan and improves survival of aged mice Guess all of us older adults need to stock up on mushrooms!!! www.nature.com/articles/s41...

nature.com

Psilocybin treatment extends cellular lifespan and improves survival of aged mice - npj Aging

npj Aging - Psilocybin treatment extends cellular lifespan and improves survival of aged mice

5306

Reposted by Jürg Bähler

Melania D'Angiolo @melaniadangiolo.bsky.social · 03/07/2025

Superhappy to share the last paper from my PhD in @litinice.bsky.social lab. We evolved yeasts with humanized telomeric repeats and discovered that they adapt through amplification of telomere-binding proteins and inactivation of the DNA damage response. www.biorxiv.org/content/10.1...

biorxiv.org

The adaptive molecular landscape of reprogrammed telomeric sequences

Telomeric sequences vary across the tree of life and intimately co-evolve with telomere-binding protein complexes. However, the molecular mechanisms allowing organisms to adapt to new telomeric sequen...

43513

Jürg Bähler @jbahler.bsky.social · 13/06/2025

After 25 years, it was wonderful to reunite with all members of our original research group!

150

Reposted by Jürg Bähler

Saccharomyces Genome Database @yeastgenome.bsky.social · 09/06/2025

FlyBase needs your help! Because of recent changes to government funding, the NIH grant that supported FlyBase has been "terminated." flybase.org

01923

Reposted by Jürg Bähler

Nathan Woodling @nathanwoodling.bsky.social · 01/06/2025

We are excited to be recruiting 3 post-doctoral researchers to study glial cell dysfunction in #agingresearch and #neurodegeneration, including one position using #Drosophila models! If you are interested, please read more below to get in touch or apply (links in thread).

Header with images of cultured cells and a Drosophila brain. Text below reads:

We are excited to be recruiting our team of 3 post-doctoral research fellows to study the mechanisms underlying ageing-dependent glial cell dysfunction and its effects on neurodegeneration! This is a three-year Medical Research Council-funded cross-disciplinary, multi-partner project with one post-doctoral fellow at each site: Edinburgh Napier, University of Glasgow, and UCL. If you are interested in glial cell biology/neurodegeneration, functional genomics and bioinformatics please get in touch or apply below: Astrocyte ageing & Bioinformatics: Fiona Kerr, ENU (f.kerr@napier.ac.uk): Apply here: Closing Date: https://jobs.napier.ac.uk/mthrprod_webrecruitment/wrd/run/etrec179gf.open?WVID=150547JMmr&LANG=USA Tuesday 24th June 2025 Microglial Ageing & Bioinformatics: Dervis Salih, UCL (dervis.salih@ucl.ac.uk): Apply here: https://www.ucl.ac.uk/work-at-ucl/search-ucl-jobs/details?jobId=35013&jobTitle=Research+Fellow Closing Date: Thursday 26th June 2025
Drosophila models of neurodegeneration: Nathan Woodling, University of Glasgow (nathan.woodling@glasgow.ac.uk): Apply here: https://www.jobs.gla.ac.uk/job/research-associate-49?source=gla.ac.uk Closing Date: Wednesday 25th June 2025

41313

Reposted by Jürg Bähler

Andrew Steele @statto.bsky.social · 31/05/2025

We found a new way to make mice live 30% longer! 🧪 #aging #longevity #rapamycin A combination of classic longevity drug rapamycin with cancer drug trametinib was more effective than either on its own. Read more about the exciting results here:

andrewsteele.co.uk

New drug cocktail makes mice live 30% longer – Andrew Steele

Rapamycin + anti-cancer drug trametinib does better than rapa on its own!

6305

Reposted by Jürg Bähler

Ursula von der Leyen @vonderleyen.ec.europa.eu · 05/05/2025

We will put forward a 500 million package for 2025-2027 to make Europe a magnet for researchers. As well as ambitious proposals for R&I in the next EU budget. We will also offer the best and brightest the right incentives to come to Europe ↓

22656192

Reposted by Jürg Bähler

MAKS 26 👀🇺🇦 @maks23.bsky.social · 24/04/2025

The Economist cover 👀

772872519

Reposted by Jürg Bähler

PomBase: The S. pombe knowledgebase @pombase.bsky.social · 09/04/2025

A periodic reminder to cite your resources. Although no @pombase.bsky.social update in this issue, we did sneak onto the cover illustration.

024

Reposted by Jürg Bähler

Melania D'Angiolo @melaniadangiolo.bsky.social · 09/04/2025

I spent a very nice couple of days at the "Hidden Cell, Dark Genome" conference in Edinburgh last week ... and even got to win a supercute eukaryotic cell 🙂 Thanks to the organisers for arranging the meeting!

2154

Reposted by Jürg Bähler

Manuel Lera-Ramirez @manu-lera.bsky.social · 01/04/2025

You can now ✅ verify your #OpenCloning sequences using sequencing data 🧬 (Sanger or Nanopore). Just load your files 📂 and see where they align! 🎯 #OpenCloning is free & Open Source, and supports most cloning methods! 🔬🛠️ 👉 Try it here: opencloning.org 🎞️ Demo video: youtu.be/n0hedzvpW88?...

1117

Reposted by Jürg Bähler

James Briscoe @jamesbriscoe.bsky.social · 13/03/2025

Together with fellow @biologists.bsky.social EiCs we've written about the unprecedented cuts & policy changes to research in the US We stand with our US colleagues during this challenging time Science transcends borders—setbacks in one nation affect us all journals.biologists.com/dev/article/...

journals.biologists.com

Science under siege: protecting scientific progress in turbulent times

As Editors-in-Chief of The Company of Biologists' journals, we have been watching with growing concern the policy changes in the United States of America (USA) and the challenges that these are creati...

08339

Reposted by Jürg Bähler

Wolfgang Huber @wkhuber.bsky.social · 08/03/2025

It's time for individuals and organizations in Europe and other democratic countries to move mission- or life-critical IT services and infrastructure outside the reach of the US government; noting that US tech companies have already largely subordinated themselves. www.huber.embl.de/group/posts/...

huber.embl.de

Digital sovereignty – Huber Group @ EMBL

The US is now a mafia-style extortionist you want to stay away from

47632

Reposted by Jürg Bähler

EMBO @embo.org · 12/02/2025

Hello everyone on Bluesky! 🧪 We are EMBO, the organization of more than 2,100 leading researchers that promotes excellence in #lifesciences in Europe and beyond. Read more: www.embo.org/about-embo/m...

Text: EMBO is on Bluesky.
Butterfly icon with text: @embo.org

422574

Reposted by Jürg Bähler

British Society for Research on Ageing @bsrageing.bsky.social · 11/02/2025

Grant rejections got you feeling low? BSRA research grants have success rates between 35-67%! We offer our members - Small Research Grants - Travel Grants - Summer Studentships Next deadline 1st March. Know the perfect person? Tag them below! bsra.org.uk/bsra-open-gr...

055

Reposted by Jürg Bähler

Dan Snow @thehistoryguy.bsky.social · 21/01/2025

'Many of us...have a feeling that we are living in a country where fanatics, hooligans and eccentrics have got the upper hand.' British Ambassador to Berlin, 1933.

28971322

Jürg Bähler @jbahler.bsky.social · 05/01/2025

You can apply to our postdoc position until 12 Jan: We are looking for a Postdoc in Functional Genomics to examine the roles of conserved yet unstudied proteins, focusing on cellular quiescence and ageing. www.ucl.ac.uk/work-at-ucl/...

ucl.ac.uk

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

046

Reposted by Jürg Bähler

Max Reuter @maxreuter.bsky.social · 18/12/2024

Second PhD project now online, co-supervised by @jbahler.bsky.social. Join us to work on the genetic architecture of environmental responses in fission yeast. Tons of existing data and resources (wild strains, MA lines, evolved populations...) to dig into. www.trees-dla.ac.uk/projects/evo...

trees-dla.ac.uk

The evolution of environmental responses | TREES DLA

Organisms are subject to environmental conditions that vary over time and space. To gain maximum fitness in the face of this variability, they need to adapt their phenotypes in such a way as to expres...

112

Reposted by Jürg Bähler

PomBase: The S. pombe knowledgebase @pombase.bsky.social · 13/12/2024

OK Pinterest, I see where you are coming from

063

Jürg Bähler @jbahler.bsky.social · 05/12/2024

We are looking for a Postdoc in Functional Genomics who will apply large-scale genetic assays, functional profiling, and systemic/computational approaches to examine the roles of conserved yet unstudied proteins, focusing on cellular quiescence and ageing. www.ucl.ac.uk/work-at-ucl/...

ucl.ac.uk

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

012

Reposted by Jürg Bähler

Agingdoc⭐David Barzilai🔔MD PhD, MS, MBA, DipABLM @agingdoc.bsky.social · 05/12/2024

Could Dark Chocolate Reduce Your Risk of Diabetes? A new study suggests that it might. We asked experts if that’s too good to be true. www.nytimes.com/2024/12/04/w...

nytimes.com

Could Dark Chocolate Reduce Your Risk of Diabetes?

A new study suggests that it might. We asked experts if that’s too good to be true.

172

Reposted by Jürg Bähler

D. Allan Drummond @dadrummond.art · 28/11/2024

Thankful for these little ones who make our bread, beer, and wine #thanksgiving #sciart

A metal sculpture of a budding yeast cell (Saccharomyces cerevisiae) in late cell division, with a large mother cell budding off a smaller daughter cell, in my hand against a white background. The cell wall is cut away to show many complex, fluid internal structures, including the nucleus and gemstone chromosomes separating after replication, mitochondria with little internal ribbed membranes, the endoplasmic reticulum, and many more. Cell wall is steel, organelles are bronze, mitotic spindle is silver, and the gemstones are apatite, which gets its blue-green color from phosphorus--the element that forms the backbone of DNA.

1529047

Reposted by Jürg Bähler

Agingdoc⭐David Barzilai🔔MD PhD, MS, MBA, DipABLM @agingdoc.bsky.social · 26/11/2024

SHADES OF BLUE Blue zones, supposed havens of longevity, have become a global brand. But skeptics think they rest on shaky science www.science.org/content/arti...

science.org

Do ‘blue zones,’ supposed havens of longevity, rest on shaky science?

Critics say extraordinary life spans reflect faulty record keeping, not healthy lifestyles

046

Reposted by Jürg Bähler

Eugene Makeyev @emakeyev.bsky.social · 18/11/2024

If you know someone who might be interested in a PhD project involving collaboration between academia and industry, here is an exciting opportunity in London: www.lido-dtp.ac.uk/apply/apply-.... We have a cool project on antisense oligonucleotide toxicity with AZ this year 😉. Please repost!

075