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Andrew Steele

@statto.bsky.social
3.5K followers 1.3K following 1K posts

Ageing biologist (aren’t we all?) Author of ageless.link Presenter of www.youtube.com/DrAndrewSteele Founder of @thelongevityinitiative.org

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Reposted by Andrew Steele
The Longevity Initiative @thelongevityinitiative.org · 6h
The longevity science community is converging on Boston for ARDD and Biomarkers of Aging… and The Longevity Initiative will be there! We’re fundraising, and looking for collaborators to bring regulation and public understanding up to speed with the latest breakthroughs in longevity science.
The Boston skyline
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Andrew Steele @statto.bsky.social · 8h
Let’s scrap the triple lock and use some of it fund longevity science which means the national care service will be cheaper! (And, more importantly, it would be cheaper because people are healthy enough not to need care…)
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Andrew Steele @statto.bsky.social · 29/09/2026
I enjoyed @xandvt.bsky.social’s new book Make Me Well so much, I made a short video about it! Check out the video, or just cut to the chase and buy the book, I guess… :)
youtube.com
Make Me Well by Xand van Tulleken is great!
YouTube video by Andrew Steele
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Andrew Steele @statto.bsky.social · 29/09/2026
Provocative and important post from @karlpfleger.bsky.social: is lifespan, and even healthspan, the wrong way to measure success in treating ageing? I enjoyed this analogy with other human megaprojects:
Consider 8 prior big problems of humanity, all of which were accomplished despite seeming daunting many decades before achievement, all of which involved multiple nontrivial subproblems (some if which may seem easy in retrospect but were nonetheless big problems when initially faced), and all of which took many years and hundreds to hundreds of thousands of people:

    the first transatlantic telegraph cable

    (durable) organ transplantation

    the moon landing (Apollo Program)

    IVF

    smallpox eradication

    HIV/AIDS treatment

    sequencing the human genome (Human Genome Project)

    creation of mRNA vaccines

Each of these problems had an obvious primary overall metrics of success, just as the aging field has lifespan, and in each of the above cases, progress towards the eventual complete solution was not well tracked by progress measured using the obvious primary outcome metric(s). For example, farthest distance from earth of a crewed mission was a terrible metric to track Apollo Program progress. % of human DNA sequenced was a terrible metric to track progress of the Human Genome Project. Length of post-transplant survival was a terrible metric to track progress towards successful durable organ transplantation. Whether or not any babies were born via IVF or a count of those that were was a terrible metric to track progress towards successful IVF techniques. Etc. In all cases such metrics if graphed would show hockey-stick style sudden progress right at the end.
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Andrew Steele @statto.bsky.social · 25/09/2026
Hi (briefly!) from London! I’m here for one night only to talk to some doctors and other healthcare pros about longevity science. And that night was last night. And I’m posting this from the airport…
Me stood outside the National Gallery on Trafalgar Square, holding a cold brew
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Andrew Steele @statto.bsky.social · 24/09/2026
It does feel like the consequences here should be exactly the same as if an employee had done it. If your models/employees are outstripping your oversight capabilities, that’s on you to fix.
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Andrew Steele @statto.bsky.social · 23/09/2026
I’m far less pessimistic than David and @adamrutherford.bsky.social are in this episode! But I’m not on the side of the tech bros either… On the central question of the show, I think it’s very unlikely we can extend lifespan without extending healthspan, because *it’s being sick that kills you*.
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Reposted by Andrew Steele
Terence Eden @edent.tel · 22/09/2026
New blog post: Are LLMs still surprisingly bad at some simple tasks? shkspr.mobi/blog/2026/09/are-llms-s… Last year I ran an experiment to test the ability of modern LLMs to correctly answer a relatively straightforward question. Every single …
shkspr.mobi
Are LLMs still surprisingly bad at some simple tasks?
Last year I ran an experiment to test the ability of modern LLMs to correctly answer a relatively straightforward question. Every single one of them got it wrong. Some missed information, some made up false statements, none were right. Of course the fanbois variously claimed that I was holding it wrong, my prompts were shit, I should have chosen better defaults, and - my favourite - that it…
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Andrew Steele @statto.bsky.social · 16/09/2026
Could a longevity breakthrough cause a pensions crisis? Check out the new post from @thelongevityinitiative.org:
thelongevityinitiative.org
Could a longevity breakthrough cause a pensions crisis? – The Longevity Initiative
A longevity breakthrough adds ten years to life expectancy. What happens to pensions?
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Andrew Steele @statto.bsky.social · 15/09/2026
Important video on peptides from @realdoctormike.bsky.social:
youtube.com
Exposing The Truth About Peptides
YouTube video by Doctor Mike
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Andrew Steele @statto.bsky.social · 11/09/2026
Good morning from Monaco! I we could somehow turn the value of all the yachts in this harbour into longevity research, I’m pretty sure we could add years to human healthy life expectancy…
Superyachts in the foreground, Monaco skyscrapers sprouting of of the hillside in the background
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Dr. Todd Ewing PhD. @ewingt-phd.bsky.social · 07/09/2026
Long-term adaptation to #plantbased #diet www.pcrm.org/news/news-re... Iron – absorbs more efficiently Creatine & carnosine – increases biosynthesis Protein – muscle mass, strength comparable Fiber – ferments more efficiently Polyphenols – higher levels of microbial metabolites
pcrm.org
The Body Doesn't Just Absorb a Plant-Based Diet—It Adapts to One, New Review Finds
WASHINGTON, DC — A new peer-reviewed review published in the journal Biology argues that much of the debate over whether plant-based diets deliver enough iron, protein, creatine, and other nutrients r...
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Andrew Steele @statto.bsky.social · 28/08/2026
Berlin was clouded out for the lunar eclipse, so I’ll just have to make do with this shot of the very-full pre-eclipse moon through high, thin cloud, with a lovely two-tone halo around it caused by optical effects with the ice crystals in the cloud.
The very-full Moon, perfectly round, surrounded by a blue and then orangey halo in a dark sky
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Andrew Steele @statto.bsky.social · 26/08/2026
Total eclipse, August 12th 2026, Mallorca, Spain. This shot is a 90-minute composite: the base picture is C2, the first moment of totality with Moon covering Sun and corona visible, and the sky split in two by the shadow; and I’ve superimposed the partial phases before and after. 🧪
Composite photo of a total solar eclipse setting over the sea in Mallorca. Repeated of images of the Sun line up along the diagonal it traced towards the horizon: the chain starts top left as small white discs, each more deeply bitten into by the Moon, narrowing to thin crescents. Two-thirds of the way down sits totality: a black disc ringed by the pearly corona, with a bright point flaring at its upper edge. Below, the crescents reappear, reddening and flattening as they sink through haze and cloud, the last few glowing deep orange just above the land.

The sky is split horizontallyby the Moon’s shadow, orange sunset light on the left, deep blue twilight on the right. Below lies a calm dark sea, a low silhouetted headland at the left and coastal mountains at the right, scattered with town lights.
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Reposted by Andrew Steele
Alom Shaha @alomshaha.bsky.social · 24/08/2026
My regular reminder that cutting down on meat, eating more vegetables, is good for your health, your wallet, and one of the best things you can do as an individual to help fight climate change. I‘ve collected some of my favourite recipes together in the link below.
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Andrew Steele @statto.bsky.social · 21/08/2026
It was my absolute pleasure to dial in from Berlin to speak with host Greg and guests Sophie (who’s sceptical) and Steve (who’s tried the Wolverine Stack!) about what we know and don’t about experimental peptides BPC-157, TB-500, GHK-Cu and more… 🧪 Listen here: www.bbc.co.uk/sounds/play/...
A screenshot of me waving from Berlin, and a selfie of Greg and Sophie in the studio with Steve and me on screen behind them
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Andrew Steele @statto.bsky.social · 13/08/2026
The first moments of totality in Mallorca #eclipse 🧪
The left side of the sky looks like sunset; the right side looks like half an hour afterwards. In the middle, a glowing ring of fire floats above distant Mallorcan hills.
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Reposted by Andrew Steele
The Longevity Initiative @thelongevityinitiative.org · 11/08/2026
What would it take to reverse 10-20 years of age-related decline in muscle, cognition and immunity? XPRIZE is spending $101 million to try and find out. At the Longevity Initiative, we believe prizes are one of the most effective tools to efficiently test different hypotheses and fund those with
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Andrew Steele @statto.bsky.social · 23/07/2026
I wonder what fraction of this is explained by the fact that a 50:50 shot at £1 million just sounds so ridiculous, I’d rather take the cash, thanks
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Andrew Steele @statto.bsky.social · 22/07/2026
It was a pleasure to speak to @thesun.co.uk about the Rejuvenation Olympics and longevity science more broadly! ‘Longevity scientist Andrew Steele, 40, from Shropshire*, describes some measures as “biohacking nonsense” and says they “are not very scientific” in their approach.’
the-sun.com
Blood-swapping, oxygen tanks & WiFi blockers - inside the 'immortality Olympics'
THEY have gruelling gym regimes and rigid routines that monitor food, sleep and nutritional intake – but unlike other athletes, these ‘Olympians’ aren’t trying to cross the finish line first.…
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Andrew Steele @statto.bsky.social · 22/07/2026
On the OpenAI hacking, I think this is the key point: do the advanced cybersecurity capabilities of these models net out at an advantage for attackers, or defenders? If the ‘good guys’ are always a few months ahead, and a few months is long enough to patch all the things, we’re golden…if not, uh-oh
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Reposted by Andrew Steele
Abilu Tangwa. @abilutangwa.bsky.social · 19/07/2026
What they don't teach you about heatwaves: It's not just heat. It's: • Your crops dying • Your river drying (Rhine is low again, disrupting shipping) • Your lungs burning from wildfire smoke • Your power grid collapsing It's everything at once.
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Andrew Steele @statto.bsky.social · 15/07/2026
It’s fun to go through this article and replace the word ‘ageing’ with the words ‘cancer’ or ‘dementia’. I don’t think longevity science is ageist—I want everyone to have a chance to be healthy, however old they are!
theguardian.com
‘Anti-ageing is anti-life’: why longevity culture is just ageism in a lab coat
Rapid scientific progress has given us the tools to stop time more convincingly than ever – but lurking behind these claims is the same fear of ageing
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Andrew Steele @statto.bsky.social · 15/07/2026
If you couldn’t see it on LinkedIn, my post on Bryan Johnson’s autoimmune gastritis diagnosis is now on my website:
andrewsteele.co.uk
Bryan Johnson’s ‘stomach-eating disease’ and the limits of biohacking – Andrew Steele
How did ‘The Most Measured Man in Human History’ have hidden autoimmune gastritis? %
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Sarah Todd @sarah-todd.bsky.social · 08/07/2026
Longevity entrepreneur Bryan Johnson has autoimmune gastritis: "My stomach is eating itself," he wrote. Experts say this could raise awareness over a chronic disease that's very hard to diagnose, and often missed by gastroenterologists: www.statnews.com/2026/07/08/b...
statnews.com
Bryan Johnson’s chronic disease is notoriously difficult to diagnose
Why longevity entrepreneur Bryan Johnson’s chronic disease is notoriously difficult to diagnose.
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Reposted by Andrew Steele
Andrew Steele @statto.bsky.social · 08/07/2026
I wrote a piece about Bryan Johnson’s diagnosis with autoimmune gastritis. Check it out here: www.linkedin.com/pulse/bryan-...
Headline: Bryan Johnson’s ‘stomach-eating disease’ and the limits of biohacking

I’m genuinely sorry to hear that Bryan Johnson is unwell. But his diagnosis with autoimmune gastritis shows the limits of flashy biohacking versus real medicine.

Johnson spends a fortune measuring himself, but it seems like he’s spent too long focussed on social-media-friendly measures like biological age scores and night-time erections while overlooking a boring marker of the body’s iron stores, ferritin.

He posted a 2,000-word (!) story to X, which reveals some fascinating details. The ‘The Most Measured Man in Human History’ was 48 and had never had a…
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Andrew Steele @statto.bsky.social · 08/07/2026
I wrote a piece about Bryan Johnson’s diagnosis with autoimmune gastritis. Check it out here: www.linkedin.com/pulse/bryan-...
Headline: Bryan Johnson’s ‘stomach-eating disease’ and the limits of biohacking

I’m genuinely sorry to hear that Bryan Johnson is unwell. But his diagnosis with autoimmune gastritis shows the limits of flashy biohacking versus real medicine.

Johnson spends a fortune measuring himself, but it seems like he’s spent too long focussed on social-media-friendly measures like biological age scores and night-time erections while overlooking a boring marker of the body’s iron stores, ferritin.

He posted a 2,000-word (!) story to X, which reveals some fascinating details. The ‘The Most Measured Man in Human History’ was 48 and had never had a…
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Reposted by Andrew Steele
Flora Graham @floragraham.bsky.social · 07/07/2026
GET HEARING AIDS ❤️ stop worrying if they're cool they're like glasses just get them and wear them this one's for the dads out there (except my dad, he's cool and wears his aids)
Hearing loss is a significant risk factor for dementia
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Reposted by Andrew Steele
The Author, Séamas O'Reilly @seamas.bsky.social · 07/07/2026
Hi, welcome back to Séamas's Boarding Pass London City Airport to Derry 23rd August 2026, boy do we have a great show for you but first I'd like to tell you all about our friends at Athletic Greens who
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Andrew Steele @statto.bsky.social · 07/07/2026
I’m genuinely sorry to hear that Bryan is unwell. But this episode shows the limits of flashy biohacking theatre vs real medicine: too much focus on social-media-friendly measures like epigenetic clocks and night time erections while overlooking low ferritin for over a decade.
Screenshot of a post from Bryan Johnson:

Bryan Johnson
@bryan_johnson
Bad news #1: 

I have an autoimmune disease. My stomach is eating itself.

Bad news #2: 

2–5% of people have this, too. Likely more, because it hides.

Good news: 

I'm going to try and solve it. Will share all.

…

(it’s very long)
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Andrew Steele @statto.bsky.social · 04/07/2026
Happy 250th birthday, America! 🎂🇺🇸 To put that into perspective: here are some animals that live even longer—some of them alive today were probably around when the Declaration was signed… 🧵
A Greenland shark, looking blue, appearing out of the inky black depths of the ocean
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Ed Hawkins @edhawkins.org · 02/07/2026
Comparing the UK heatwaves of June 1976 and June 2026... Daytime maximum & night minimum temperatures were much hotter in 2026. Details: maxima over 21st-30th June in both years. Uses provisional 2026 HadUK-Grid data from Met Office NCIC. Note the difference scale is larger for night minimums.
Comparing peak temperatures during June 1976 and June 2026Comparing night-time temperatures during June 1976 and June 2026
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Matthew Cobb @matthewcobb.bsky.social · 01/07/2026
Amazing work, though for the moment these things/devices can’t synthesise new ribosomes, so they die/stop working after a few generations when the ones they have been given wear out. Read it and be amazed! And it’s non-patented!
nytimes.com
This Cell Feeds, Grows and Reproduces. And It’s Manmade.
From chemical building blocks, scientists have created synthetic cells that have most of the hallmarks of life.
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Andrew Steele @statto.bsky.social · 01/07/2026
‘The Interventions Testing Program, which discovered or validated many of the best longevity drugs in mice, runs on a budget that’s only about twice what Bryan Johnson spends on his health every year.’ Are billionaires are obsessed with longevity? Check out my new article for BBC Science Focus: 🧪
sciencefocus.com
Why billionaires could reverse ageing for everyone – but keep refusing to | BBC Science Focus Magazine
The ultra-rich keep spending millions to live forever – so why are the real breakthroughs going unfunded?
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Ed Hawkins @edhawkins.org · 29/06/2026
Just one possible outcome... but the GFS weather forecast model is suggesting 40-41°C is possible in the UK around 7th July. This is a long-range forecast with significant uncertainty, but the fact that we are even seeing such values fairly regularly in the forecasts is extraordinary.
GFS for 7th July
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Andrew Steele @statto.bsky.social · 29/06/2026
This weather isn’t just bad for your health because it’s hot: it also affects the air we breathe. 🧪
youtube.com
The invisible health risk from heatwaves (it’s not the heat)
YouTube video by Andrew Steele
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Andrew Steele @statto.bsky.social · 26/06/2026
This silver parasol reflects both UV (sunburn, skin ageing) and IR (heat), so I’m trying it out in the oppressive 35°C heat in London. I’d like to do a randomised trial to see if it actually affects my core body temperature, but I think it would be unethical to put myself in the control group.
Me holding a silver umbrella on a London street, dressed in a stupid hot shirt and sunglasses.
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Tony Yates @t0nyyates.bsky.social · 24/06/2026
I think this is a fair point, up to a point. I'm qualifying because there is a long and established debate in the field, with all the arguments worked through. Those working on this have engaged.
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Andrew Steele @statto.bsky.social · 24/06/2026
I’m starting to think this whole ‘climate change’ thing wasn’t such a great idea
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Aoḋán Ó Conġaile @tinydonkey.bsky.social · 04/06/2026
If other news was reported like climate change:
A picture of a couple driving and laughing with the text "road fatalities highest in ten years"
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Geoff Brumfiel @gbrumfiel.bsky.social · 18/06/2026
EXLCUSIVE: An analysis by two MIT researchers shows how Russia's nuclear-powered cruise missile actually works. And guys, it's not pretty. 🚀☢️🤢🧵 www.npr.org/2026/06/18/n...
npr.org
Report: Russia's nuclear-powered 'Skyfall' missile is dirty and dangerous
MIT researchers think they've worked out exactly how Russia's Burevestnik nuclear-powered missile flies. "It's almost certainly a terrible idea," one analyst said. "But it's not an impossible idea."
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Andrew Steele @statto.bsky.social · 22/06/2026
A new study suggests the uptick in young people getting cancer is because they’re biologically older. Target the ageing process and you might help the 30-year-olds too! And a proper interventional study would finally tell us what these ageing clocks are actually measuring…
nature.com
Biological aging and generational shifts in early-onset cancer risk - Nature Medicine
Analyses of population cohorts found that young adults exhibited earlier systemic and organ-specific aging, which was associated with increased risk of early-onset cancer compared with older adults bo...
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Andrew Steele @statto.bsky.social · 21/06/2026
The days will start getting shorter… …wait for it… …now! Summer solstice 2026, June 21st, 08:25 UTC (09:25 BST, 10:25 CEST).
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Andrew Steele @statto.bsky.social · 19/06/2026
Vaccines can literally prevent cancer—and the new HPV jab statistics are even more remarkable than the headline. New article:
andrewsteele.co.uk
Vaccines can literally prevent cancer – Andrew Steele
The new HPV vaccine statistics are even more remarkable than the headlines suggest.
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Rob Ford @robfordmancs.bsky.social · 19/06/2026
Racism Goldilocks strategy is hard to execute
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Jacob Gudiol @jacobgudiol.traningslara.se · 19/06/2026
"If we assume that this is governed by a Poisson distribution—a good first approximation for random events—the probability of observing zero deaths in 2020–24 without the vaccine is: P(0) = e⁻²²·⁷ ≈ 1.4 × 10⁻¹⁰ That's roughly 1 in 7 billion—ie, essentially impossible"
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Andrew Steele @statto.bsky.social · 19/06/2026
Vaccines can literally prevent cancer—and the new HPV jab statistics are even more remarkable than the headline. New article:
andrewsteele.co.uk
Vaccines can literally prevent cancer – Andrew Steele
The new HPV vaccine statistics are even more remarkable than the headlines suggest.
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Andrew Steele @statto.bsky.social · 18/06/2026
Incredible: vaccines can literally prevent cancer! Truly one of humanity’s greatest achievements. Now let’s do some of the other awful viruses that seed chronic disease.
bbc.com
HPV vaccine means young women now have 'close to zero' risk of cervical cancer death
A new study finds that hundreds of lives have been saved since school-age girls were offered the HPV jab in 2008.
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Andrew Steele @statto.bsky.social · 18/06/2026
I’m pretty sure a ladybird would beat a skateboard in a race
Captcha, with the text ‘Select all items that would beat the object in a race’, a picture of a skateboard, and then a grid of pictures of cars, ladybirds, starfish and a bench
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