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Javier Irazoqui

@javierira.bsky.social
1.5K followers 263 following 404 posts

Professor of Microbiology @ UMass Chan Medical School | Host-Microbe Interactions | Bacteria | Immunology | Artificial Intelligence

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Javier Irazoqui @javierira.bsky.social · 08/10/2026
eLife Latest: Exploring AI’s potential for improving research engagement elifesciences.org/inside-elife...
elifesciences.org
eLife Latest: Exploring AI’s potential for improving research engagement
We have partnered on a number of projects exploring the discoverability and navigation of research by machines and humans alike, laying the groundwork for a new era of AI-driven research communication...
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Reposted by Javier Irazoqui
Kathleen Bachynski @bachynski.bsky.social · 08/10/2026
Possible assignment for students: 1) Statistics: How many possible confounding variables can you identify that might be skewing this data? 2) Philosophy: What are some ethical problems with evaluating the success of higher education programs in terms of the salaries of their graduates after 4 years?
nytimes.com
A College-by-College Guide to Which Majors Pay Off — or Don’t
College is one of the biggest investments you’ll ever make. We built a tool to compare earnings of nearly every major at nearly every school in the country.
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Javier Irazoqui @javierira.bsky.social · 07/10/2026
Here it's usually turkeys
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Javier Irazoqui @javierira.bsky.social · 07/10/2026
This is a BIG DEAL Large transgene arrays cause aberrant transcription and synthetic molting defects - PubMed pubmed.ncbi.nlm.nih.gov/42837616/
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Javier Irazoqui @javierira.bsky.social · 02/10/2026
"Why is It Often Assumed that Black Faculty Members Will Teach the Diversity Courses?" - HigherEdJobs www.higheredjobs.com/AskTheExpert...
higheredjobs.com
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Javier Irazoqui @javierira.bsky.social · 28/09/2026
Teaching Students How To Learn, Not Just What To Learn www.higheredjobs.com/Articles/art...
higheredjobs.com
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Javier Irazoqui @javierira.bsky.social · 25/09/2026
Damn microbes
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Javier Irazoqui @javierira.bsky.social · 25/09/2026
Hey check out our preprint on #neuroimmunology! Curious to hear about potential parallels in #humans Cholinergic activation of HLH-30/TFEB promotes C. elegans infection resilience. | bioRxiv www.biorxiv.org/content/10.6...
biorxiv.org
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Javier Irazoqui @javierira.bsky.social · 25/09/2026
oh come on. It's just draft v1.
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Javier Irazoqui @javierira.bsky.social · 25/09/2026
Unrealistic goals or dreams... for a Hollywood ACTOR? Based on what criteria is becoming a Hollywood movie star a realistic goal or dream? smh
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Chronicle of Higher Education @chronicle.com · 25/09/2026
Syracuse missed its undergraduate-enrollment target, creating a $30-million deficit. Now its new chancellor wants a mostly faculty committee to propose “disruptive and potentially unpopular” reforms — and answer what a $95,000-a-year education is worth. chroni.cl/4xLOIlR
chronicle.com
After Missing Its Enrollment Goal, Syracuse U. Is Questioning Everything
The university sets out to ask what its degree is really worth — and hints at “potentially unpopular” reforms.
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Javier Irazoqui @javierira.bsky.social · 25/09/2026
There's a federal inspection system?
static.klipy.com
Will Poulter's 'You Guys' Meme Reaction
ALT: Will Poulter's 'You Guys' Meme Reaction
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Javier Irazoqui @javierira.bsky.social · 25/09/2026
@vambros.bsky.social something like this here? 😀
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Jonathan Eisen @phylogenomics.bsky.social · 25/09/2026
Nice work @cedricfeschotte.bsky.social
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Richard Sever @richardsever.bsky.social · 25/09/2026
AI discovery of new enzymes "not a breakthrough...a wrinkle on what we know" www.nytimes.com/2026/09/24/s...
nytimes.com
Anthropic’s A.I. Is Teaching Itself Biology. Now It’s Made Its First Discovery.
Scientists at the company announced their first finding: a group of enzymes whose function is unknown.
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Javier Irazoqui @javierira.bsky.social · 25/09/2026
I believe this is why GenX sees the best adoption rates and the highest ROI on GenAI
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Heather Randell @heatherrandell.bsky.social · 25/09/2026
Yet another example of how AI can be useful *once you already have deep knowledge and experience in a field* whereas using it as a student actively prevents the acquisition of that knowledge. www.nytimes.com/2026/09/25/o...
nytimes.com
Opinion | A.I. Has Made Me a Better Doctor. It’s Made Med Students Worse. (Gift Article)
I’m confident in my mastery over what doctors do — and less confident about my continued mastery of an ever-evolving universe of facts.
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Javier Irazoqui @javierira.bsky.social · 25/09/2026
Scientific culture in the age of AI | Nature Cell Biology www.nature.com/articles/s41...
nature.com
Scientific culture in the age of AI - Nature Cell Biology
Recent changes in Genentech’s scientific organization, occurring as the company makes artificial intelligence (AI) increasingly central to its research strategy, highlight a broader question facing bi...
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Reposted by Javier Irazoqui
Jonathan Kagan @jkagan1.bsky.social · 23/09/2026
Today, the Toll-like Receptors reveal a new mechanism of signal transduction: Receptor-Free Signal Transduction. www.nature.com/articles/s41...
nature.com
TRAM promotes Toll-like-receptor-free myddosome signal transduction - Nature
TRAM is a regulator of myddosome assembly through dissociating MyD88 from the TLR–TIRAP complex to enable myddosome maturation and durable downstream signal transduction.
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Ivan Zanoni @lozanzi.bsky.social · 23/09/2026
#ChangeTheDogma! #TLRpower! @jkagan1.bsky.social @danielhfisch.bsky.social &co show @nature.com that TRAM, so far believed to control endosomal TLR4 signaling & interferon #IFN production, is essential to release the #myddosome from #TIRAP & the plasma membrane allowing full NFkB signaling!
nature.com
TRAM promotes Toll-like-receptor-free myddosome signal transduction - Nature
TRAM is a regulator of myddosome assembly through dissociating MyD88 from the TLR–TIRAP complex to enable myddosome maturation and durable downstream signal transduction.
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anil oza @aniloza.bsky.social · 23/09/2026
Semafor reporting that the White House is paring back this reported executive order
screenshot reading "“There is still a question of ‘Is it dead?’ versus ‘We don’t actually have a choice but to wait, so we might as well not do this before the midterms,’” said one pharmaceutical industry lobbyist.

If the administration had advanced the original scope of the planned NIH order, it could sink Congress’ ability to pass a stopgap spending bill at the end of the year.

“They have to” pull back, a person familiar with the talks said. “They won’t be able to pass a CR on December 11 if they issue an EO.”"
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Javier Irazoqui @javierira.bsky.social · 23/09/2026
"L'etat c'est moi" 👑
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Carrie Sokol @carriesokol.bsky.social · 23/09/2026
1/ Why can you encounter an allergen repeatedly before becoming allergic to it? In our new @cp-immunity.bsky.social paper, led by the wonderful Xueping Zhu, we asked whether the sensory neurons that first detect allergens might carry a record of earlier exposures. 🧵 www.cell.com/immunity/ful...
cell.com
Sensory neuronal mTORC1 kinase signaling establishes neuroimmune memory that initiates allergic immunity
How cumulative environmental allergen exposures are encoded by peripheral sensory neurons to shape immune responsiveness is unclear. Zhu et al. show that protease allergens induce an mTORC1-dependent,...
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Dan Vergano @danvergano.bsky.social · 23/09/2026
Ipsos: "Teachers, doctors, scientists, and soldiers. Unsurprisingly, these are the professions trusted most by Americans." www.ipsos.com/en-us/profes...
ipsos.com
Professions Americans do and don’t trust
Below are five charts on which professions earn the most trust from Americans, which professions earn the least, and how Americans feel about the ordinary American
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Colin Carlson @colincarlson.bsky.social · 23/09/2026
What's behind this tidal wave of epidemics? In the largest study ever conducted on emerging infectious diseases, we show that the popular explanation - "our relationship with nature is out of balance" - doesn't hold up. Out now in Nature, after half a decade of work: www.nature.com/articles/s41...
nature.com
The anthropogenic fingerprint on emerging infectious diseases - Nature
Emerging infectious disease outbreak risks are ubiquitous worldwide, and highest in landscapes where people, livestock and fragmented natural ecosystems coexist, but detection and data ...
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Greg Folkers @gregfolkers.bsky.social · 23/09/2026
Wpost: I’m a Republican senator. America needs more science, not less. By Dave McCormick @washingtonpost.com wapo.st/4hFN3JI 💥
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Margot Finn @eicathomefinn.bsky.social · 23/09/2026
Whereas the UK is carefully cultivating its pipeline into academia and science (in the European sense), mindful of the demands of the present and the future?????? Ignoring the elephants in the room won't disappear them. With a sharing link for 3 non-subscribers. giftarticle.ft.com/giftarticle/...
giftarticle.ft.com
The next generation of American scientists is fading away
While the Trump administration racks up ‘wins’ in its anti-woke crusade, the US is eroding its talent pipeline
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Chronicle of Higher Education @chronicle.com · 23/09/2026
Graduates in the most AI-exposed majors are increasingly struggling to find post-graduation employment, according to a new working paper from the U.S. Census Bureau. The reporting also shows where some graduates are landing instead. chroni.cl/4y6U641
chronicle.com
The Most AI-Exposed College Graduates Are Entering Another Great Recession
A new Census Bureau report offers concrete evidence of how certain majors are faring in the job market — which may shift what students choose to study.
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ImmuNoah's Ark (Noe Rodriguez) @immunoah.bsky.social · 22/09/2026
Really nice to see out this interesting study from @carriesokol.bsky.social Sensory neuronal mTORC1 kinase signaling establishes neuroimmune memory that initiates allergic immunity: Immunity www.cell.com/immunity/ful...
cell.com
Sensory neuronal mTORC1 kinase signaling establishes neuroimmune memory that initiates allergic immunity
How cumulative environmental allergen exposures are encoded by peripheral sensory neurons to shape immune responsiveness is unclear. Zhu et al. show that protease allergens induce an mTORC1-dependent,...
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Reposted by Javier Irazoqui
YouGov America @today.yougov.com · 23/09/2026
Sep 22-23 poll of 7,593 U.S. adults (±1.4 points) Which comes closest to your view about vaccinating children against measles? % who say vaccination should be required for children U.S. adults 55% Democrats 73% Independents 52% Republicans 41% yougov.com/en-us/daily-...
YouGov survey results by political party for the question, "Which comes closest to your view about vaccinating children against measles?"
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Dominique Baker @bakerdphd.bsky.social · 23/09/2026
This is also why you've gotta read the papers when it comes time for p&t
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Javier Irazoqui @javierira.bsky.social · 23/09/2026
"The future of the American university lies in leadership that recommits to a clear purpose, which the committee defines as promoting a human-centered, integrated learning ecosystem to cultivate sound judgment." - Cornell University’s Committee on the Future of the American University
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Javier Irazoqui @javierira.bsky.social · 23/09/2026
www.insidehighered.com/news/institu...
insidehighered.com
How a Cornell Committee Wants the University to Change
A Cornell committee made nearly 70 recommendations that it says will reorient the university to its core purpose.
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Javier Irazoqui @javierira.bsky.social · 22/09/2026
www.insidehighered.com/news/quick-t...
insidehighered.com
Judge Rules ED Can’t Cut Grants Based On ‘Ideologies’
A federal judge on Thursday struck down an Education Department directive that cut $600 million from teacher-training grants based on what officials called “divisive ideologies.”
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Javier Irazoqui @javierira.bsky.social · 22/09/2026
www.insidehighered.com/news/governm...
insidehighered.com
Researchers Accuse NIH of Viewpoint Discrimination
The National Institutes of Health’s screening process for grants violates the First Amendment, more than a dozen researchers argue.
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Catherine Rampell @crampell.bsky.social · 20/09/2026
Lysenkoism lives. www.nytimes.com/2026/09/20/s...
nytimes.com
White House Moves to Take Control of N.I.H. Grants
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Javier Irazoqui @javierira.bsky.social · 21/09/2026
Trump asked budget chief to draft order bringing health research funding under his control - POLITICO apple.news/AhV_NaiF0Qty...
apple.news
Trump asked budget chief to draft order bringing health research funding under his control — POLITICO
The move came after the NIH director refused Trump’s request to cut Harvard grants in an Oval Office meeting.
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Javier Irazoqui @javierira.bsky.social · 14/09/2026
www.insidehighered.com/news/tech-in...
insidehighered.com
The “Nonexistent” Research on AI’s Benefits for Education
Colleges are going all in on artificial intelligence. But it could be a long time before independent research emerges on how it should—or shouldn’t—be used to improve learning outcomes.
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Javier Irazoqui @javierira.bsky.social · 09/09/2026
Worried Anthropic researchers warn that AI 'could kill all humans' - The Verge apple.news/ASCNgXUEcQeW...
apple.news
Worried Anthropic researchers warn that AI 'could kill all humans' — The Verge
A departing researcher says AI companies are ‘gambling with our lives’ by racing to develop self-improving AI. A senior Anthropic safety researcher has said there is more than a 10 percent chance arti...
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Javier Irazoqui @javierira.bsky.social · 08/09/2026
UMass Boston’s chancellor to step down after leading campus through major evolution - WBUR News apple.news/A0pUrUc_XTvu...
apple.news
UMass Boston’s chancellor to step down after leading campus through major evolution — WBUR News
Under his tenure, UMass Boston climbed the U.S. rankings of public research universities, earning top-tier status from the Carnegie Foundation in 2025. And he helped oversee a long-overdue $293 millio...
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Javier Irazoqui @javierira.bsky.social · 07/09/2026
Why I Want More AI at Dartmouth - The Atlantic apple.news/AfVoAItU-Sui...
apple.news
Why I Want More AI at Dartmouth — The Atlantic
Universities that hide from the technology will merely secure their irrelevance.
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Javier Irazoqui @javierira.bsky.social · 04/09/2026
The fight over COVID’s origins came for a top virologist. Now his life’s work is at stake. - Bloomberg Businessweek apple.news/APdyRhY4oScy...
apple.news
A Top Virus Scientist Stared Down Covid Lab-Leak Proponents. Now His Life’s Work Is at Stake — Bloomberg Businessweek
The battle over Covid’s origins has come for Bob Garry, who’s faced some of the world’s deadliest viral threats.
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Javier Irazoqui @javierira.bsky.social · 04/09/2026
Rogue OpenAI agents appear to have organized another attack using a German wiki - The Verge apple.news/AGT90ML6eTLS...
apple.news
Rogue OpenAI agents appear to have organized another attack using a German wiki — The Verge
A swarm of rogue AI agents from OpenAI reportedly commandeered a German website and transformed it into a messaging board for other agents, with officials staying quiet about the incident for weeks as...
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elizabethginexi.bsky.social @elizabethginexi.bsky.social · 03/09/2026
The Trump administration released new rules that could revoke tax-exempt status from any school offering targeted support to Black or other minority students, a sweeping change that opens another front in the president’s campaign to reshape American education. www.nytimes.com/2026/09/03/b...
nytimes.com
Trump Administration Renews Push to Strip Schools of Tax-Exempt Status (Gift Article)
The Treasury Department released rules that would upend how schools qualify for tax-exempt status, a new front in the president’s campaign against higher education.
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Michael Lobel @mlobelart.bsky.social · 03/09/2026
Gloria Steinem photographed by Yousuf Karsh in 1972. RIP a true trailblazer & icon💓
B&W photo of Gloria Steinem sitting crosslegged holding a beautiful cat
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Yonatan Grad @yhgrad.bsky.social · 03/09/2026
Here's a new method for microbial GWAS now that the limiting factor has shifted from sequencing isolates-there are many collections of sequenced isolates!-to phenotyping enough isolates to power GWAS. Cool new AMR biology in Neisseria gonorrhoeae, too! See @dhelekal.bsky.social's thread!
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jacob galapagos @jacobgalapagos.bsky.social · 03/09/2026
It’s think for yourself thursday
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Samantha Butler @samanthabutler.bsky.social · 02/09/2026
Please spread the news - the Department of Neurobiology at UCLA is hiring. This is an open rank search for all and any amazing neuroscientists! Please apply here by Nov 15th, first review end of October : recruit.apo.ucla.edu/JPF11296
recruit.apo.ucla.edu
Open-rank tenure-track faculty position
University of California, Los Angeles is hiring. Apply now!
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Javier Irazoqui @javierira.bsky.social · 03/09/2026
Apocalypse prep or pure pragmatism: what is behind Peter Thiel’s move to Argentina? - The Guardian apple.news/ATjz1AvaHRUG...
apple.news
Apocalypse prep or pure pragmatism: what is behind Peter Thiel’s move to Argentina? — Guardian US
Relocation coincides with proposed laws that opponents say would entrench power of US tech billionaires in country
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Javier Irazoqui @javierira.bsky.social · 03/09/2026
Axios interview: Sam Altman's sobering siren - Axios apple.news/AwguOVmSkSLi...
apple.news
Axios interview: Sam Altman's sobering siren — Axios
CHAPEL HILL, N.C. — OpenAI CEO Sam Altman gave Axios an eye-opening preview of the power and the risks of coming AI models, including his own Astra, which is expected to be released any day now.
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