iiinova — where your digital self keeps evolving

Irini Topalidou @irinakitop.bsky.social · 08/10/2026

A big thank you to the one and only @harmitmalik.bsky.social for such a thoughtful and memorable gift and for an unforgettable collaboration at Fred Hutch’s Basic Scuences Division @basicsci.fredhutch.org ! We love you, Harmit! ♥️

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Reposted by Irini Topalidou

Harmit Singh Malik @harmitmalik.bsky.social · 04/09/2026

Structure and sequence fill evolutionary gaps for essential centromeric proteins. Work by @jeremyahollis.bsky.social, @irinakitop.bsky.social, & Jason Stonick. Article by Kelsey Woodruff. www.fredhutch.org/content/www/... Paper: www.science.org/doi/10.1126/...

fredhutch.org

Structure and sequence fill evolutionary gaps for essential centromeric proteins

Researchers in the Basic Sciences Division track evolutionary origins for an essential protein

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Irini Topalidou @irinakitop.bsky.social · 17/08/2026

Friends and colleagues, I’d like to invite you to my seminar this Thursday, the 20th, as part of the GSA Seminar Series featuring the 2026 GSA Award recipients. I’d be very happy to see you there! 😊 ECT: 1:00–2:00 PM WCT: 10:00–11:00 AM

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Harmit Singh Malik @harmitmalik.bsky.social · 08/07/2026

The ever amazing Steve Henikoff! @fredhutch.org @basicsci.fredhutch.org

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Irini Topalidou @irinakitop.bsky.social · 02/07/2026

This T-shirt is hilarious, Piali! I hope you enjoy the celebration. Looking forward to the pictures!!!

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Irini Topalidou @irinakitop.bsky.social · 01/07/2026

Many congrats to the amazing @jeremyahollis.bsky.social and the one-and-only @harmitmalik.bsky.social So much fun to be part of this collaboration!!! Worms, fish, and many other metazoan species come together to build this beautiful story!!! 🐛🐟🐀

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Robert Reich @rbreich.bsky.social · 29/06/2026

With heat waves shattering temperature records across the globe, leading to needless deaths, let me just say that history will not look fondly on those who put fossil fuel profits above saving the planet.

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Jason Shepherd @jasonsynaptic.bsky.social · 29/06/2026

Very excited for our new paper, now out in @cellcellpress.bsky.social! /🧵 The protein Tau forms intracellular toxic tangles in neurons in Alzheimer’s disease and Tauopathies. Tau pathology slowly spreads from cell-to-cell but the mechanisms are not clear /1 authors.elsevier.com/sd/article/S...

authors.elsevier.com

Arc mediates intercellular tau transmission via extracellular vesicles

Tau pathology spreads cell to cell, but the mechanisms of intercellular tau transmission remain unclear. We find that the neuronal gene Arc is critica…

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Irini Topalidou @irinakitop.bsky.social · 27/06/2026

Thank you Ethan!! Piali will send me the protocol. I’m glad it worked well for you!

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Irini Topalidou @irinakitop.bsky.social · 26/06/2026

It’s been a while since I mentioned how much I appreciate the worm community! Thank you all for replying to my message and for being so generous and eager to help! I appreciate you all!

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Irini Topalidou @irinakitop.bsky.social · 26/06/2026

Great! Thank you so much, Michael!!

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Irini Topalidou @irinakitop.bsky.social · 25/06/2026

Great! Thank you very much, Javier and Matt

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BWJones @bwjones.bsky.social · 24/06/2026

Progress in cancer research has been one of the incredible areas of biomedical advancement over the past two decades. Many cancers which were absolute death sentences just a few years ago are now chronic, managed conditions. And this was only possible through NIH/NCI/NIAID research/funding.

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Irini Topalidou @irinakitop.bsky.social · 24/06/2026

Hey C. elegans friends! What's your preferred method for cell-specific knockout or knockdown? Would love any paper recommendations too! Thank you!!!

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Irini Topalidou @irinakitop.bsky.social · 10/06/2026

Nikos, I’m incredibly thankful for your kind words. They mean so much to me, especially coming from someone whose work and character I deeply respect and admire

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Irini Topalidou @irinakitop.bsky.social · 10/06/2026

Thank you for your kind words, Katerina. When I wrote it, I had all of us in mind 🥹. I'm glad it resonates with you.

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Irini Topalidou @irinakitop.bsky.social · 09/06/2026

Thank you so much, Ethan! I feel that it’s less of an autobiographical article and more of a perspective shared by most of us who moved out of our countries. I’m glad you are one of us (worm fellow)! 🐛🩵

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Irini Topalidou @irinakitop.bsky.social · 09/06/2026

The GSA gave me the opportunity to write an article in GENETICS reflecting on my journey as an immigrant in the USA and how those experiences have shaped my life and career. Thank you to all of my mentees, friends, and family who have supported me along the way 🙏 academic.oup.com/genetics/adv...

academic.oup.com

A second life

Abstract. The Genetics Society of America Mentorship Award recognizes members of the scientific community for exceptional mentoring of geneticists at any c

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Irini Topalidou @irinakitop.bsky.social · 10/03/2026

Truly honored to be part of this inspiring story, driven by the super talented student @jeremyahollis.bsky.social and made possible through the collaboration of four different labs at @basicsci.fredhutch.org. Science at its best!!!

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Harmit Singh Malik @harmitmalik.bsky.social · 03/03/2026

My awesome colleague, @yarimura.bsky.social, is recruiting a postdoc to start at the end of 2026 or early 2027! His lab uses cryo-EM to uncover structural basis of key chromatin events using native complexes isolated from human cells or Xenopus egg extracts! careers-fhcrc.icims.com/jobs/30706/p...

careers-fhcrc.icims.com

Fred Hutchinson Cancer Center

Fred Hutch is dedicated to the elimination of cancer and related diseases as causes of human suffering and death.

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Irini Topalidou @irinakitop.bsky.social · 26/02/2026

Suzanne thank you so much! I miss you! 😘♥️

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Irini Topalidou @irinakitop.bsky.social · 25/02/2026

Thank you as well to the GSA selection committee for this honor. My heart is full of gratitude. Receiving appreciation like this is rare, and I do not take it for granted. @genetics-gsa.bsky.social @senguptalab.bsky.social

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Irini Topalidou @irinakitop.bsky.social · 25/02/2026

I can’t find enough words to thank Aakanksha @singhvilabglia.bsky.social for nominating me for this award. Aakanksha truly went out of her way to show her appreciation and I am forever grateful 🥹💝

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Irini Topalidou @irinakitop.bsky.social · 25/02/2026

Thank you so much, Sue. I feel so lucky and happy to be part of BSD!

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Irini Topalidou @irinakitop.bsky.social · 25/02/2026

Thank you so much, Navin! This one goes to our worms!!! 🐛♥️🤗

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Irini Topalidou @irinakitop.bsky.social · 25/02/2026

Petros σε χιλιοευχαριστω και ελπίζω να είσαι καλά! ♥️

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