Teles-Reis et al. present EyaHOST, a modular Drosophila system that enables clone generation in the eye disc with independent genetic manipulation of other tissues. EyaHOST uses an Eya-KD “kick-out” s...

Here, combining structural, proteomics and biochemical analyses, the authors elucidate how the keystone gut bacterium Ruminococcus bromii assembles a specialized enzyme complex, the amylosome, to effi...

Although metagenomic sequencing has revealed a rich microbial biodiversity in the mammalian gut, methods to genetically alter specific species in the microbiome are highly limited. Here, we introduce ...