Institut Necker Enfants Malades @inem-necker.bsky.social · 20h@marco-pontoglio.bsky.social @fabiolaterzi.bsky.social @philipmour.bsky.social 000
Institut Necker Enfants Malades @inem-necker.bsky.social · 20h@guillaumeandrieu.bsky.social @mathieucoureuil.bsky.social @goffinlab.bsky.social @matthieumahevas.bsky.social @esegura-lab.bsky.social @dobrawaamiri.bsky.social @flaviegarampon.bsky.social @myckaelarouabah.bsky.social @auroreclaudetaupin.bsky.social @membramics-lab.bsky.social 101
Institut Necker Enfants Malades @inem-necker.bsky.social · 20h🔬 La Fête de la Science à l'INEM ce samedi 10 octobre a attiré de nombreuses personnes qui ont pu découvrir les coulisses de la recherche biomédicale ! Merci à tous.tes d'avoir participer à cette belle journée de partage 🙏 #FDS2026 121
Institut Necker Enfants Malades @inem-necker.bsky.social · 06/10/2026Les travaux menés par Rima El Hage et par le groupe FEROSTEM cherchent à faire progresser la recherche sur le cancer du sein et à développer de nouvelles thérapies pour les patientes. Ce projet bénéficie du soutien de la Ligue Contre Le Cancer et de @upcite.bsky.social (Emergence Idex 2025).institut-necker-enfants-malades.frPhysiopathologie de la Prolactine et de l'Hormone de croissance | INEMNos recherches s'articulent principalement autour de trois thèmes centraux : 000
Institut Necker Enfants Malades @inem-necker.bsky.social · 06/10/2026🎀 Pour #OctobreRose, l'INEM met en avant Rima El Sage, chercheuse dans le groupe FEROSTEM dirigé par Ahmed Hamaï, de l'équipe de @goffinlab.bsky.social. 🔬 Rima El Sage étudie la pertinence de l’homéostasie du fer et de la ferroptose dans la biologie et le ciblage des cellules souches cancéreuses. 121
Reposted by Institut Necker Enfants MaladesManvendra Singh @manusingh.bsky.social · 28/09/20261/8 Proud and super thrilled to share our preprint, “A single-nucleus regulatory atlas links transposons to adult hippocampal neurogenesis.”, led by Umut, Fede, and Souad, the FIRST from our #RETROGEN lab @inem-necker.bsky.social . www.biorxiv.org/content/10.6... shrt thread on what we found 🧵 2149
Reposted by Institut Necker Enfants MaladesJournal of Clinical Investigation @jci.org · 15/09/2026Cilia–to–basement membrane signaling initiates cystogenesis in the kidney doi.org/10.1172/JCI1... The Cover features work by Mazloum et al. @inem-necker.bsky.social showing basement membrane remodeling drives cyst formation in autosomal dominant kidney disease 142
Institut Necker Enfants Malades @inem-necker.bsky.social · 29/09/2026Pour la Fête de la Science 2026, l’INEM vous accueille pour une journée de découverte avec des ateliers conçus pour éveiller votre curiosité scientifique ! Pour en savoir plus : lnkd.in/eZVvR2st 👉 Samedi 10/10, 10h - 16h30 📍 Institut Necker - Enfants Malades, 160 rue de Vaugirard, Paris 15e 000
Institut Necker Enfants Malades @inem-necker.bsky.social · 08/09/2026🧑🔬 Don’t miss out the review in @cp-immunity.bsky.social from @venteclefn.bsky.social team on metabolic, obesity and cancer! Learn more about the IMMEDIAB team at INEM: tinyurl.com/529wysnc 021
Institut Necker Enfants Malades @inem-necker.bsky.social · 07/09/2026🔬 New publication, now out in #ScienceImmunology led by Mathieu Deygas in Pablo Vargas team, shows that Adaptive motility enables neutrophils to rapidly navigate confined capillaries 📰 To read the article: tinyurl.com/52vxuhmp 33316
Institut Necker Enfants Malades @inem-necker.bsky.social · 04/09/2026La publication "Immunometabolic endotypes define distinct clinical trajectories in type 2 diabetes" dans @cp-cellmetabolism.bsky.social de l'équipe @nicolasven.bsky.social a été mise en avant par un communiqué de presse de l'Inserm. 💡Pour en savoir plus sur l'équipe IMMEDIAB : tinyurl.com/47hwzxmu 000
Institut Necker Enfants Malades @inem-necker.bsky.social · 01/09/2026🔬 New publication from the @philipmour.bsky.social team with with Stamatia Gioftsidi and Takuto Hayashi at INEM in @cp-devcell.bsky.social on how "Postnatal Pax7-expressing limb cells are multipotent and generate non-myogenic lineages that persist into adulthood" 000
Institut Necker Enfants Malades @inem-necker.bsky.social · 31/08/2026👏 Congratulations to @venteclefn.bsky.social team for their new publication in @cp-cellmetabolism.bsky.social about immunometabolic endotypes defining distinct clinical trajectories in type 2 diabetes! 000
Reposted by Institut Necker Enfants MaladesKidney International @kidneyint.bsky.social · 10/08/2026Non-HLA antibodies worsen the histological phenotype and prognosis of antibody mediated rejection in kidney allografts doi.org/10.1016/j.kint.2026.06.031 #NephSky #MedSky #OpenAccess @inserm.fr @inem-necker.bsky.social @uzleuven.bsky.social 021
Institut Necker Enfants Malades @inem-necker.bsky.social · 06/08/2026@olivieraubert.bsky.social @danyanglicheau.bsky.social @julienzuber.bsky.social 000
Institut Necker Enfants Malades @inem-necker.bsky.social · 06/08/2026🧪 New publication from @fabiolaterzi.bsky.social team at INEM entitled "Non-HLA antibodies worsen the histological phenotype and prognosis of antibody mediated rejection in kidney allografts" in @kidneyint.bsky.social Read it here: tinyurl.com/mtmww249tinyurl.comNon-HLA antibodies worsen the histological phenotype and prognosis of antibody mediated rejection in kidney allograftsAntibody-mediated rejection (AMR) remains a leading cause of kidney allograft failure, with both HLA and non-HLA antibodies implicated in its pathogenesis. The contribution of non-HLA antibodies (non-... 111
Institut Necker Enfants Malades @inem-necker.bsky.social · 05/08/2026New research now out in Nature Cell Biology, led by Nathaniel F. Henneman in Ganna Panasyuk team, shows that nuclear class 3 PI3K co-activates fasting-specific chromatin remodelling. Read the article here: tinyurl.com/4h4vybsb Learn more about it and about the first author: tinyurl.com/2pdbjdk7 000
Institut Necker Enfants Malades @inem-necker.bsky.social · 04/08/2026They all have been awarded funding from the @agencerecherche.bsky.social under the #AAPG 2026 call for proposals! 000
Institut Necker Enfants Malades @inem-necker.bsky.social · 04/08/2026Congratulations to @marco-pontoglio.bsky.social, Julien Diana, @delevoyecedric.bsky.social, Pierre Isnard, @auroreclaudetaupin.bsky.social, Anne Jamet, @esegura-lab.bsky.social, @aminetoubal.bsky.social, Nicolas Venteclef, Jean-François Gauthier, Laurence Arbibe and @mario-pende.bsky.social! 131
Institut Necker Enfants Malades @inem-necker.bsky.social · 31/07/2026🧪 New publication from the @fabiolaterzi.bsky.social team with @olivieraubert.bsky.social and @danyanglicheau.bsky.social at INEM on how "Impaired thymic function is independently associated with an increased risk of posttransplant infections in kidney recipients" 001
Institut Necker Enfants Malades @inem-necker.bsky.social · 30/07/2026🔬 Don't miss out the new publication in @jcellsci.bsky.social from the MEMBRANICs lab at INEM! 030
Reposted by Institut Necker Enfants MaladesInstitut Imagine @institutimagine.bsky.social · 24/07/2026🔬 How do ADPKD cysts form? A JCI study by @hkd-l.bsky.social at Institut Imagine & Frank Bienaimé's group @inem-necker.bsky.social shows: without polycystin-1, the tubule sleeve gets softer, not stiffer. This loosening lets the tube expand. A new therapeutic target! 👏 📄 jci.org/articles/vie... 074
Institut Necker Enfants Malades @inem-necker.bsky.social · 22/07/2026📅 SAVE THE DATE | 2026 INEM Prestige Lecture Series From 1 to 4 December 2026, INEM will welcome Professor Fiona Watt, @embo.org Director and an internationally recognised leader in stem cell biology. 📍 INEM : 160 rue de Vaugirard, 75015 Paris More details on our website: tinyurl.com/kp2z4ybv 020
Institut Necker Enfants Malades @inem-necker.bsky.social · 20/07/2026👏 A huge congratulations to Guillaume Canaud on being awarded the 2026 Mendel Medal, an award recognising his significant work on rare diseases linked to mutations in the PIK3CA gene and on the development of innovative treatments for patients! @eshg.bsky.social 031
Institut Necker Enfants Malades @inem-necker.bsky.social · 17/07/2026New research now out in Cell Death & Disease from @natureportfolio.nature.com, led by Véronique Baud in @mario-pende.bsky.social team, shows that the alternative NF-kB RelB subunit is a novel critical sensor of lipid metabolism to promote tumor development. 000
Institut Necker Enfants Malades @inem-necker.bsky.social · 15/07/2026New research now out in Cellular & Molecular Biology Letters, led by Edouard Le Guillou in Ganna Panasyuk team, shows that restoration of lysosomal membrane integrity in cell models of Pompe disease depends on fatty acid synthase and its product palmitic acid. tinyurl.com/ytu86hj9 010
Institut Necker Enfants Malades @inem-necker.bsky.social · 13/07/2026New research now out in @jci.org, led by Manal Mazloum in @fabiolaterzi.bsky.social team, shows that cilia to basement membrane signalling is a biomechanical driver in models of autosomal dominant polycystic kidney disease tinyurl.com/5ahn88ns 011
Institut Necker Enfants Malades @inem-necker.bsky.social · 17/04/2026📢 INEM Friday Seminar Series At INEM Auditorium 2 Today, Zayna Chaker from the Institute of Functional Genomics of Lyon will present her work at the INEM seminar series "The puzzle of adult brain stem cell coordination: A functional and evolutionary perspective" Details here➡️ tinyurl.com/5xmnjkpn 010
Reposted by Institut Necker Enfants MaladesInstitut Imagine @institutimagine.bsky.social · 09/04/2026🧫 Wrapping up today's fantastic MAGIC seminar is @manusingh.bsky.social (@inem-necker.bsky.social). His talk: "Single-Cell Mapping of the Reawakening of Ancient Foes in Ageing Disorders." A deep dive into the molecular & cellular mechanisms of Alzheimer. Thanks to all speakers & see you next week! 🧪 053
Institut Necker Enfants Malades @inem-necker.bsky.social · 10/04/2026📢 INEM Friday Seminar Series At INEM - Auditorium 3 Today, Marat Yusupov, from IGBMC, Strasbourg, France, will present his work at the INEM seminar series "Study of ribosome structure for the development of drugs" Details here ➡️ www.institut-necker-enfants-malades.fr/node/4474 010
Institut Necker Enfants Malades @inem-necker.bsky.social · 20/03/2026📢 INEM Friday Seminar Series Today, Robert E. Schwartz, from Weill Cornell Medical College, New York, USA, will present his work at the INEM seminar series "Vascular Identity, Stromal Diversity, and the Challenge of Building a Bioartificial Liver" Details here ➡️ tinyurl.com/szfbjmdc 000
Institut Necker Enfants Malades @inem-necker.bsky.social · 20/03/2026Retour sur la retraite de l'INEM de ces 2 derniers jours près de Fontainebleau Les membres de l'INEM se sont réunis pour des conférences scientifiques… et vulgarisées 🎤 et pour des activités ludiques🎉 👏 Bravo aux présentateur·ices Et merci aux organisateur·rices et sponsors pour cet événement ! 010
Institut Necker Enfants Malades @inem-necker.bsky.social · 16/03/2026Le 6 mars 2026, Fabiola Terzi, directrice de l’Institut Necker Enfants Malades, a reçu la Légion d'honneur des mains de Gérard Friedlander. Une reconnaissance qui honore un parcours et les valeurs d’ouverture portées par l’INEM. Plus d'information sur le site de l'INEM : tinyurl.com/3ssxkc2b 011
Institut Necker Enfants Malades @inem-necker.bsky.social · 13/03/2026Aujourd'hui vendredi 13 mars, l'invité du Friday Seminar à l'INEM était Aude Bernheim, chercheuse de l'Institut Pasteur. Invitée par la cellule égalité professionnelle de l'INEM, son séminaire s'intitulait "Ce que le féminisme fait découvrir à la biologie" Plus d'info ici : tinyurl.com/55jmhnh6 000
Institut Necker Enfants Malades @inem-necker.bsky.social · 05/03/2026📢 INEM Friday Seminar Series 📅 March 6th 📍 INEM Auditorium 3 Today, Mercedes Ricote, from the Centro Nacional de Biotecnología of Madrid, will present the INEM seminar series "Mother´s milk drives maturation of heart metabolism" Details here ➡️ www.institut-necker-enfants-malades.fr/node/4444institut-necker-enfants-malades.frMercedes Ricote | INEM 000
Institut Necker Enfants Malades @inem-necker.bsky.social · 27/02/2026📢 Paris Postdocs Seminar 📅 March 5th 📍 INEM Room 4 (-1) Next week, Alexandre Pierga from @institutimagine.bsky.social will present the @parispostdocs.bsky.social "Loss of MTPAP disrupts mtRNA processing causing upregulation of type I interferon signaling" ➡️ tinyurl.com/4stwnnu7 010
Institut Necker Enfants Malades @inem-necker.bsky.social · 27/02/2026📢 INEM Friday Seminar Series 📅 February 27th 📍 INEM Auditorium 3 Today, Gioacchino Natoli from the European Institute of Oncology, Milan will present for the INEM seminar series "Control of genic and extragenic transcription in inflammation and cancer" Details here ➡️https://tinyurl.com/3pfa6u29 000
Institut Necker Enfants Malades @inem-necker.bsky.social · 19/02/2026📢 INEM Friday Seminar Series 📅 February 20th 📍 INEM Auditorium 3 Tomorrow, Vassili SOUMELIS from Inserm U976 HIPI will present for the INEM seminar series "Multi-Omic data for patient stratification and personalized medicine in immuno-inflammatory diseases" Details here ➡️ tinyurl.com/jezjvcab 000
Institut Necker Enfants Malades @inem-necker.bsky.social · 18/02/2026📢 Paris Postdoc Seminar 📅 February 19th 📍 INEM Room 4 (-1) Tomorrow, Hugo Barreto from @institutcochin.bsky.social will present the @parispostdocs.bsky.social "Eco-evolutionary dynamics of bacterial strains across Human gut microbiotas" ➡️ tinyurl.com/5p82htud 121
Institut Necker Enfants Malades @inem-necker.bsky.social · 12/02/2026📢 Journée des Fournisseurs/Supplier's Day 📅 February 17th 📍 Institut Necker Enfants Malades Next week, INEM is hosting its Supplier's Day ! Over 20 suppliers available to meet with Necker campus researchers & collaborators all day 👩🔬👨🔬 Organised by the HappyNEM association ➡️ tinyurl.com/mpekc5tb 000
Reposted by Institut Necker Enfants MaladesInstitut Jacques Monod @ijmonod.bsky.social · 10/02/2026📢 Paris Postdoc Seminar 📅 February 17th 📍 Institut Jacques Monod Next week, Maria Laura Rojas ( @inem-necker.bsky.social ) will present the @parispostdocs.bsky.social «Organelle Crosstalk and Mitochondrial Renewal in Metabolic Adaptation to Shear Stress» ➡️ buff.ly/FRRVp5B 021
Reposted by Institut Necker Enfants MaladesBioconf @bioconf.bsky.social · 05/02/2026Upcoming seminar by Hugo Barreto: If you are interested in meeting with the speaker, please reach at Institut Necker Enfants Malades, Thursday 19 February 2026 at 10:00. More info 001
Institut Necker Enfants Malades @inem-necker.bsky.social · 04/02/2026[PUBLICATION] The @goffinlab.bsky.social lab shows a promising therapeutic strategy to mitigate prostate cancer progression towards CRPC — now out in EMBO Molecular Medicine @embomolmed.org 👏🏼 Co-first authors: Manon Baurès & Anne-Sophie Vieira Aleixo 🔗 link.springer.com/article/10.1...link.springer.comTargeting pre-existing club-like cells in prostate cancer potentiates androgen deprivation therapy - EMBO Molecular MedicineA critical knowledge gap in prostate cancer research is understanding whether castration-tolerant progenitor-like cells that reside in treatment-naïve tumors play a direct role in therapy resistance a... 021
Reposted by Institut Necker Enfants MaladesInstitut Jacques Monod @ijmonod.bsky.social · 02/02/2026📢 Paris Postdoc Seminar 📅 February 17th 📍 Institut Jacques Monod Maria Laura Rojas ( @inem-necker.bsky.social ) will present the @parispostdocs.bsky.social «Organelle Crosstalk and Mitochondrial Renewal in Metabolic Adaptation to Shear Stress» ➡️ buff.ly/FRRVp5B 055
Institut Necker Enfants Malades @inem-necker.bsky.social · 30/01/2026[SEMINAR] 🗓️ Join us today, for a #seminar with Henri-Francois RENARD, group leader at Université de Namur. Pr. RENARD will explore the molecular mechanisms of clathrin-independent endocytosis. Don’t miss it! Invited by @membramics-lab.bsky.social 121
Institut Necker Enfants Malades @inem-necker.bsky.social · 28/01/2026[PUBLICATION] The Coureuil lab shows how MDA phages promote N. meningitidis colonisation by pili variants selection — out in @natcomms.nature.com 👏🏼 First & last authors: Clémence Mouville & Emmanuelle Bille 🔗 nature.com/articles/s41467-025-67441-w 📰 Read more on INEM website: tinyurl.com/mr3j39xrnature.comNeisseria meningitidis filamentous phage MDA promotes colonisation by selecting hyperadhesive pili variants - Nature CommunicationsIn Neisseria meningitidis, the filamentous phage MDA is associated with biofilm formation during epithelium colonisation. Here, the authors investigate the relationship between phage MDA infection and... 031
Institut Necker Enfants Malades @inem-necker.bsky.social · 15/01/2026[SEMINAR] 📢 Paris Postdoc Seminar at INEM on Thursday January 22 Maria Lizarralde-Iragorri from @institutimagine.bsky.social will present the @parispostdocs.bsky.social seminar "Investigating Hematopoiesis and Erythropoiesis in Sickle Cell Disease" More info ➡️ tinyurl.com/ykjnp873 031
Institut Necker Enfants Malades @inem-necker.bsky.social · 12/01/2026[PUBLICATION] The Schnupf lab shows how SFB remodel their adhesive tip during development from unicellular to filamentous forms - now out in @natcomms.nature.com 👏🏼 First author: @anaraquelcruz.bsky.social 🔗 nature.com/articles/s41467-025-66892-5 📰 Read more on INEM website: tinyurl.com/yjfvbzu2 011
Institut Necker Enfants Malades @inem-necker.bsky.social · 09/01/2026[PUBLICATION] The MODUL-CF study group reports that CFTR modulators can reverse bronchial dilatations in adolescents with cystic fibrosis @thelancet.com 👏🏼 First author & INEM team leader: Isabelle Sermet-Gaudelus 🔗 doi.org/10.1016/S2213-2600(25)00248-6 📰 More on INEM website: tinyurl.com/3fdk752cdoi.orgRedirecting 000