Benito-Martínez, Salavessa and colleagues show that keratin intermediate filaments and microtubules control the three-dimensional perinuclear position of melanin-containing organelles, shielding the D...

Autophagy is a crucial ‘self-eating’ mechanism used by eukaryotic cells to degrade and recycle cytosolic materials. A recent study by Da Graça et al. reports that the dynamic mobilization of endosome–...

Da Graça et al. identify ER-endosome contact sites as critical hubs for autophagosome biogenesis, where starvation triggers sequential endosome tethering to ER exit sites. This spatiotemporal coordina...