Sign in

Gregor lab

@gregorlab.bsky.social
96 followers 124 following 31 posts

@imgprague research group studying cytoskeleton organization in cell and tissue mechanics. Tweets by Martin Gregor and lab members. #mechanobiology www.img.cas.cz/group/martin-gregor

PostsRepliesMedia
Gregor lab @gregorlab.bsky.social · 21/07/2026
“Illuminating the Architecture of Thought” by our Postdoc @GemperleJakub (@imgprague) has won the Prague @EuroBioImaging Node Picture of the Month. Congrats jakub! @imgprague imcf.natur.cuni.cz/IMCF/picture-o… #neuron #Live-cell imaging of a mature primary neuron through microinjected GFP
110
Gregor lab @gregorlab.bsky.social · 21/05/2026
“The Aquarelle of Motion” by our PhD student Vera Getmanchuk-Zaporoshchenko (@imgprague) has won the Prague @EuroBioImaging Node Picture of the Month. Congrats Vera! imcf.natur.cuni.cz/IMCF/picture...
210
Gregor lab @gregorlab.bsky.social · 05/05/2026
@Gregor_lab #labretreat 2026: two days of exploring new angles of our projects, hiking, enjoying great food, and sharing lots of laughter in the beautiful scenery of Český ráj. Thanks to Vera, Káča, and Černá Louže for making it happen this year!
010
Gregor lab @gregorlab.bsky.social · 30/04/2026
Happy to be part of this story: Jan Famera and Lea M. Skultéty from Gymnázium Karla Čapka in Dobříš advanced to the next round of Students’ Professional Activities, Czech national high-school research competition, with work on muscular dystrophy performed in our lab. Huge congratulations!
000
Gregor lab @gregorlab.bsky.social · 20/03/2026
Great @imgprague seminar by our PhD student Srikant Ojha @sojha148 on hepatic stellate cell #mechanosignaling and its potential for new therapeutic approaches in liver #fibrosis. Lab of Integrative Biology @Gregor_lab is leveling up 🚀
010
Reposted by Gregor lab
Institute of Molecular Genetics @imgprague.bsky.social · 19/01/2026
🚀Open PhD position! Lab of Integrative Biology @gregorlab.bsky.social is seeking a new talent. 💪Ultimate goal: Develop AAV-compatible mini-plectins to treat muscular dystrophy and cardiomyopathy 👉Profile: MSc, interest in biology, motivation, independence 🧡APPLY: img.cas.cz/phd
002
Gregor lab @gregorlab.bsky.social · 31/12/2025
Our paper on the anti-cancer effects of the first-in-class plectin inhibitor plecstatin is out in @MolOncology! Great work by @OutlaZuzana & @Kosla_Jan. Collaborations with @Selma_OsMyers (@MedUniWien), Sam Meier (@univienna) & Lukas Frick (@UZH). Check at pubmed.ncbi.nlm.nih.gov/41467448/
030
Gregor lab @gregorlab.bsky.social · 22/12/2025
It’s been an eventful year for all of us! Our Christmas party was a great reminder of the team spirit behind the science & we’re excited to take on the challenges of 2026. Merry Christmas & Happy New Year from the Laboratory of Integrative Biology!
040
Gregor lab @gregorlab.bsky.social · 09/10/2025
At #WMS2025 in Vienna? Check out our PhD student Vera Getmanchuk-Zaporoshchenko’s poster on phenotyping a preclinical model of plectin-related LGMD. #LGMD #MuscularDystrophy"
010
Gregor lab @gregorlab.bsky.social · 23/09/2025
Huge congrats to our PhD student, Piyush Bisht, for presenting his work on Flipper-TR probe applied to Circulating Tumor Cells at #Czechbioimaging's Imaging Principles of Life 2025 conference in Brno! He had amazing discussions and valuable feedback. Way to go, Piyush!" @imgprague.bsky.social
011
Gregor lab @gregorlab.bsky.social · 03/09/2025
Two hours of tough work to make 2 minutes of science sparkle ✨ Today we helped popularize our #magnetogenetics manuscript by Gemperle Jakub for NUVR_CZ. Tune in to TV NOVA evening news!
120
Gregor lab @gregorlab.bsky.social · 20/08/2025
“Cellfie: A triple-stained portrait of HeLa’s senescence” by Spoorthi Suresh Hiremath (@imgprague.bsky.social; ‪@gregorlab.bsky.social‬) has won the Prague @eurobioimaging.bsky.social Node Picture of the Month. Congrats Spoorthi!
051
Gregor lab @gregorlab.bsky.social · 07/07/2025
"It's official 🎉: Our remote magnetic control of #endosomes, driving invasive protrusions in living cells, has landed in #ScienceAdvances! #Magnetogenetics meets #Rabs! The journey was wild, but it works! 🔥 www.science.org/doi/full/10.... @imgprague.bsky.social #3Dmatrix #CellBiology @science.org
science.org
Live-cell magnetic manipulation of recycling endosomes reveals their direct effect on actin protrusions to promote invasive migration
Repositioning of Rab25 vesicles containing formin and integrin cargos to the cell periphery promotes protrusion formation.
1188
Gregor lab @gregorlab.bsky.social · 25/06/2025
Huge congratulations to our PhD student Srikant Ojha for winning the Microscopic Picture of the Year 2024/2025 award! Well deserved!
000
Gregor lab @gregorlab.bsky.social · 29/04/2025
30th Cytoskeletal Club was opened in Liblice on Monday, 28 April. The first day is complete - great keynote by Martijn Gloerich (@GloerichLab) from @UMCUtrecht on Mechanical control of epithelial cell division. More to come!
033
Gregor lab @gregorlab.bsky.social · 27/04/2025
Great 2 days at MedUni Vienna hosted by @Selma_OsMyers from Institute of Medical Chemistry and Pathobiochemistry. Giving a seminar on our concept of targeting mechanical homeostasis in cancer. Great meeting the Lilli Winter and Osmanagic-Myers Labs. Evening with our mentor Gerhard Wiche.
030
Gregor lab @gregorlab.bsky.social · 11/04/2025
Excited to share our new @elife.bsky.social in collaboration with @Schiller lab.: Dynamics of compartment-specific proteomic landscapes of hepatotoxic and cholestatic models of liver fibrosis doi.org/10.7554/eLif... #ECMatrix #chaperone #Clusterin #ECMresearch #Collagen #Integrin #AFM #Proteomics
061
Gregor lab @gregorlab.bsky.social · 24/03/2025
Happy Monday... Happy to share the picture of our colleague Srikant Ojha winning EuBI Node Picture of the Month 2024/25 competition! (imcf.natur.cuni.cz/IMCF/picture...)
"A microscopic cage: The image has 2 channels: black, phalloidin (actin) and color, alpha smooth muscle actin. The structure shows an architectural masterpiece of actin-bundle caging the nucleus in activated primary hepatic stellate cells isolated from mice."
130
Gregor lab @gregorlab.bsky.social · 21/03/2025
Excited to share our new @elife.bsky.social paper! We show that plectin fuels the growth & metastasis of hepatocellular carcinoma (HCC). Targeting plectin could be promising in HCC therapy, as we show using a novel plectin inhibitor, plecstatin! elifesciences.org/articles/102... #plectin #HCC
elifesciences.org
Plectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis
Plectin drives hepatocellular carcinoma progression and metastasis through cytoskeletal reorganization and oncogenic signaling, making it a promising therapeutic target for overcoming therapy resistan...
122
Gregor lab @gregorlab.bsky.social · 13/03/2025
Hello! The Martin Gregor lab @imgprague is now on Bluesky! We will tweet about our #mechanobiology work, pretty microscopy images and videos and more. FOLLOW us!
010