The first and arguably most critical level of gene expression is transcription of the genetic information from DNA into RNA. Within this process, tran…

Abstract. Start–stop elements are translation regulatory elements in 5′ untranslated regions (UTR) of eukaryotic transcripts, consisting of a start codon i

Ve středu 11. března proběhla ve společenském sále knihovny přednáška Barbory Valáškové na téma jak mikrobiom ovlivňuje náš mozek

Pathogenic Bordetella bacteria use protein adhesins to infect the ciliated respiratory epithelia of vertebrate hosts. In this work, we show that the filamentous hemagglutinin FhaB adhesin of Bordetell...

Covering: 2010 up to 2025 (May) Mycotoxins, secondary metabolites produced by filamentous fungi, are highly toxic contaminants of food crops. These contaminated plants pose a significant health risk…

The alveolate alga Chromera velia is a close relative of parasitic apicomplexans that possesses an unusual Photosystem I. Here, the authors present the cryo-EM structure of this complex, revealing sev...

Nemažte lyže vosky s fluorem, škodí zdraví i horám - apelují na lyžaře mikrobiologové. Profesionální lyžaři fluorové vosky už používat nesmějí. Rekreační lyžaři je ale do stop stále zanáší.

The non-proteinogenic amino acid β-cyano-l-alanine (AlaCN) is a plant toxin formed during HCN detoxification. The presence of AlaCN and its dipeptide,…

Říká se mu druhý mozek. Mikrobiom ovlivňuje v našem těle všechno. Co mu prospívá a jak souvisí i s dlouhověkostí, vysvětluje v rozhovoru laureát Ceny Neuron Martin Schwarzer.

Pathogens can exploit the plasticity of host immune cells, such as the pathway of monocyte differentiation into macrophages and dendritic cells. This review discusses how microbial pathogens hijack th...

Author summary Systemic infection and survival of Salmonella within host cells depend on expression of effector proteins that manipulate host cell functions. Here, we show that expression of these eff...

The Czech Science Foundation (GACR), as the most important provider of funding for basic research projects in the Czech Republic, will begin funding over

Trichophyton benhamiae var. luteum is an emerging fungal pathogen responsible for a rising number of skin infections transmitted from guinea pigs to humans, especially in Europe. We investigated why t...

Koulukiusaamisen jäljet näkyvät aivoissa vielä aikuisenakin | Verkkouutiset

The authors show that regenerating liver requires de novo pyrimidine synthesis and it uses ammonia as precursors differentially as it traverses the liver zones. Tracing studies and spatial metabolomic...