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Institute of Biotechnology

@ibtcas.bsky.social
52 followers 49 following 56 posts

Insight into structural, protein and cellular biology leads to new therapies. www.ibt.cas.cz

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Akademie věd ČR @akademievedcr.bsky.social · 29/09/2026
🐝 Speciální přípravek chrání včely 🦠 Konkrétně proti dvěma významným nemocem (mor včelího plodu a hniloba včelího plodu). 🔬 Za jeho vývojem stojí odborníci z @ibtcas.bsky.social
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Institute of Biotechnology @ibtcas.bsky.social · 08/09/2026
🔬 Cells exchange mitochondria. Is it time to recognize horizontal mitochondrial transfer as a field of its own? A new Opinion article co-authored by our researchers argues that HMT is a fundamental physiological phenomenon relevant far beyond disease. doi.org/10.1016/j.tcb.2026.08.012
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Institute of Biotechnology @ibtcas.bsky.social · 13/08/2026
🧠 Save the date for the next Cytoskeletal Brew seminar! 📅 September 3 at 5:00 PM 📍 Viničná 7, Room B3, Prague 2 (the full address is also available via the QR code on the poster) For more information, please visit: sites.google.com/natur.cuni.c...
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Institute of Biotechnology @ibtcas.bsky.social · 05/08/2026
Young scientists off duty 🔬🌞 Our PhD students and young scientists met for a summer BBQ organised by the PhD Committee - good food, games, relaxed conversations and even a few four-legged guests 🐶
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Institute of Biotechnology @ibtcas.bsky.social · 23/07/2026
Výsledky experimentů nekončí publikací. Surová data mají hodnotu i pro další výzkum. 🔬 Na vývoji databáze MBDB se podílel tým BTÚ AV ČR vedený Janem Dohnálkem. Více v článku: vedavyzkum.cz/veda/veda/mo...
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Institute of Biotechnology @ibtcas.bsky.social · 16/07/2026
Our colleague Jiří Černý chaired the RNA 3D session at the Benasque conference on Computational Approaches to RNA Structure and Function and presented DNATCO 5.0, combining NtC-based conformational analysis with NA-VAL validation of RNA and DNA models.
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Institute of Biotechnology @ibtcas.bsky.social · 10/07/2026
Centre of Molecular Structure never sleeps - even during the quietest week of summer. With Jan Blaha, they collected high-quality X-ray diffraction data on our D8 Venture, aiming to resolve a protein structure at ~1.8 A. Looking forward to collecting data with you!
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Reposted by Institute of Biotechnology
IOCB Prague @iocbprague.bsky.social · 03/07/2026
The symposium was chaired by @dmsabatini.bsky.social of IOCB Boston, whose work has significantly contributed to the understanding of the #mTOR signaling pathway, and Kateřina Rohlenová of @ibtcas.bsky.social, who investigates the metabolic relationships between cancer cells and healthy cells.
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Institute of Biotechnology @ibtcas.bsky.social · 03/07/2026
🧬 Cancer cells and immune cells may compete for mitochondria. A new Trends in Cancer article looks at horizontal mitochondrial transfer and its possible role in tumor progression, antitumor immunity and future therapies. Read more: www.sciencedirect.com/science/arti...
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Reposted by Institute of Biotechnology
Czech Academy of Sciences @czechacademy.bsky.social · 02/07/2026
A new study in @natcomms.nature.com shows that mechanical properties of breast carcinoma tissue can be linked to priming anti-cancer immune responses. Research by Giorgio Scita (University of Milan), @ibtcas.bsky.social, et al. Study ➡️ www.nature.com/articles/s41...
Image source: Institute of Biotechnology, Czech Academy of Sciences
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Institute of Biotechnology @ibtcas.bsky.social · 02/07/2026
Our colleagues Gabriela Pavlínková, Valerie Fabríciová, Romana Bohuslavová and Věra Slaninová attended the European Islet Study Group Conference 2026 in Barcelona. Our team presented two posters and joined discussions with the international islet research community.
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Institute of Biotechnology @ibtcas.bsky.social · 17/06/2026
10 years of BIOCEV. 🔬 A decade of collaboration across institutions, disciplines and people and an important part of Czech biomedical research with international reach. We are glad to be part of this project.
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Institute of Biotechnology @ibtcas.bsky.social · 26/05/2026
Towards Instruct Biennial conference in Brussels by example. @instruct-eric.bsky.social covers travel costs to the experiments up to 500€, up to 550€ when not flying. Pro tip: many European locations are accessible by night trains from Linz. See you in Brussels!
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Institute of Biotechnology @ibtcas.bsky.social · 26/05/2026
Droplet Digital PCR World on Tour 2026 has started at BIOCEV 🧬 Hosted by GeneCore in collaboration with Bio-Rad, the workshop combines ddPCR talks with hands-on work on the QX700 instrument in the GeneCore lab. Practical training continues tomorrow.
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Institute of Biotechnology @ibtcas.bsky.social · 04/05/2026
We hosted two student groups in our labs this April 🧬 One visited through Hejbni vědou!, organised by Asociace genové terapie, and the other came from Sunny Canadian School. A closer look at how research works in practice.
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Institute of Biotechnology @ibtcas.bsky.social · 28/04/2026
𝐒𝐭𝐫𝐮𝐜𝐭𝐮𝐫𝐚𝐥 𝐛𝐢𝐨𝐥𝐨𝐠𝐲 𝐢𝐧 𝐚𝐜𝐭𝐢𝐨𝐧 𝐚𝐭 𝐭𝐡𝐞 𝐂𝐂𝐏𝟒 𝐖𝐨𝐫𝐤𝐬𝐡𝐨𝐩 𝟐𝟎𝟐𝟔 𝐢𝐧 𝐍𝐨𝐯é 𝐇𝐫𝐚𝐝𝐲 🧬 ~30 students from across Europe and 20 tutors coming together to learn and share knowledge in crystallography and cryo-EM. Our colleagues Petr Kolenko and Jan Dohnálek contributed with lectures. @structbiocssb.bsky.social
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Institute of Biotechnology @ibtcas.bsky.social · 22/04/2026
🔬 Hands-on workshop alert! Learn nanoDSF, DLS & Spectral Shift methods - and try them on your own samples at the NanoTemper Technologies in CMS workshop. 📅 May 5–6, 2026 📍 BIOCEV, Vestec 👉 More info: 1url.cz/2eEKO
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Institute of Biotechnology @ibtcas.bsky.social · 08/04/2026
📢 Free webinar on MOSBRI project results Discover the eSPC software suite and the Molecular Biophysics Database (MBDB) - tools designed to support and streamline your research. 📅 April 8 | 13:00 CEST 👉 cassyni.com/events/WDEKq...
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Institute of Biotechnology @ibtcas.bsky.social · 07/04/2026
🧬 Next Cytoskeletal Brew is coming up! This time with Giampietro Schiavo talking about axonal transport and neurodegeneration. 📅 April 28 | 5:00 PM 📍 CAS building, Národní 3 A nice chance to connect with the local cytoskeleton community! 👉 sites.google.com/natur.cuni.c...
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Institute of Biotechnology @ibtcas.bsky.social · 30/03/2026
Great to see the structural biology community come together in Nové Hrady for the #XXIIDiscussions and CIISB User Meeting 🧬 👏 Congrats to all student awardees - especially our colleague Jiří Srogoň for the @structbiocssb.bsky.social poster prize!
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Institute of Biotechnology @ibtcas.bsky.social · 25/03/2026
📢You’re invited to a WiSe@IBT guest lecture at BIOCEV: 𝐌𝐚𝐫𝐜𝐢 𝐋𝐨𝐛𝐞𝐥, 𝐏𝐡𝐃 𝐓𝐡𝐞 𝐄𝐯𝐨𝐥𝐮𝐭𝐢𝐨𝐧 𝐨𝐟 𝐏𝐫𝐞𝐧𝐚𝐭𝐚𝐥 𝐒𝐭𝐫𝐞𝐬𝐬 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡: 𝐓𝐡𝐫𝐞𝐞 𝐃𝐞𝐜𝐚𝐝𝐞𝐬 𝐨𝐟 𝐃𝐢𝐬𝐜𝐨𝐯𝐞𝐫𝐢𝐞𝐬 📅 21 April 2026 | 10:00 a.m. 📍 BIOCEV Auditorium Don't miss out on this unique opportunity! 👉Register: 1url.cz/5eweM
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Reposted by Institute of Biotechnology
Czech Academy of Sciences @czechacademy.bsky.social · 24/03/2026
Tau protein modifications emerging in early stages of Alzheimer’s disease disrupt cellular cytoskeleton protection and enable its degradation. ➡️ www.ibt.cas.cz/en/news/Tau-... @ibtcas.bsky.social @sciencecharles.bsky.social @cnrs.fr @iphys-cas.bsky.social
Phosphorylation of the tau protein disrupts the protection of the cellular cytoskeleton and allows its degradation.

Image source: Institute of Biotechnology, Czech Academy of Sciences.
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Institute of Biotechnology @ibtcas.bsky.social · 16/03/2026
BIOCEV SEMINAR SERIES 📆 19. 3. 2026 🕒 3 p.m. 📍BIOCEV, Vestec
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Institute of Biotechnology @ibtcas.bsky.social · 13/03/2026
Two days with the EOSC NRP project team in the Vysočina region 🤝 A chance to step back from day-to-day tasks, share updates across teams, discuss open questions, and look at where the project is heading next. Great discussions and many useful exchanges across activities. #OpenScience #ResearchData
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Institute of Biotechnology @ibtcas.bsky.social · 13/03/2026
🧬 Our colleague Gabriela Pavlínková is serving as Guest Editor for the Scientific Reports collection “Advances in Embryonic Development.” Proud to see her shaping this exciting research area.
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Institute of Biotechnology @ibtcas.bsky.social · 27/02/2026
Join us for the next seminars from the BIOCEV Seminars Series! 📆 5. 3. 2026 🕒 3 p.m. 📍BIOCEV, Vestec
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Institute of Biotechnology @ibtcas.bsky.social · 26/02/2026
📢 𝐍𝐮𝐜𝐥𝐞𝐢𝐜 𝐀𝐜𝐢𝐝 𝐒𝐭𝐫𝐮𝐜𝐭𝐮𝐫𝐞 𝐀𝐧𝐧𝐨𝐭𝐚𝐭𝐢𝐨𝐧 & 𝐏𝐫𝐞𝐝𝐢𝐜𝐭𝐢𝐨𝐧 𝐇𝐚𝐜𝐤𝐚𝐭𝐡𝐨𝐧 𝟐𝟎𝟐𝟔 Over three days, participants will work on interoperable workflows, data standards, and benchmarking approaches with an emphasis on reproducibility and community reuse. Learn more 👉 1url.cz/ZeugF Register here 👉 1url.cz/neugR
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Institute of Biotechnology @ibtcas.bsky.social · 11/02/2026
🎉 Congratulations to Jana Campbell on receiving the 2025 PhD Thesis Award from the Czech Society for Structural Biology. Kudos also to her supervisor Cyril Barinka. 👏 👉 More: 1url.cz/Zezie
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Institute of Biotechnology @ibtcas.bsky.social · 29/01/2026
📢 We are hiring! • Postdoctoral Researcher in Molecular Transport Dynamics • PhD Positions in Quantitative Imaging of Ciliary Transport – Track A: Single-Molecule Imaging – Track B: Imaging Technology & Method Development 📍 BIOCEV, near Prague 👉 Details via QR codes
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Institute of Biotechnology @ibtcas.bsky.social · 28/01/2026
Little visitors, big curiosity 💛 Children from Vestec Kindergarten explored the laboratories of the Centre of Molecular Structure and discovered that science can be fun from a very young age. 🧪👀 Thank you for the visit! ✨
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Institute of Biotechnology @ibtcas.bsky.social · 23/01/2026
Carta Genum, founded by Lukáš Valihrach and Daniel Žucha, raised pre-seed funding from Czech Founders VC and joined the Sherpa accelerator. 🧬 They aim to make biological data analysis accessible — without black-box AI or coding barriers. 👉https://1url.cz/gJy66
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Institute of Biotechnology @ibtcas.bsky.social · 19/01/2026
✨ 𝐆𝐚𝐭𝐞𝐬 𝐨𝐟 𝐈𝐦𝐚𝐠𝐢𝐧𝐚𝐭𝐢𝐨𝐧 ✨ Mouse cerebellum captured through the lens of science and art. 🏆 December Picture of the Month 📸 Lenka Gmiterková
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Reposted by Institute of Biotechnology
Mikrobiologický ústav AV ČR @mbuavcr.bsky.social · 15/01/2026
A new paper🧬Bacteria sense the antibiotic rifampicin through a widespread dual-promoter based alarm system Nucleic Acids Research (2026) Lab of Microbial Genetics and Gene Expression IMIC, @iocbprague.bsky.social @ibtcas.bsky.social @akademievedcr.bsky.social ➡️ academic.oup.com/nar/article/...
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Institute of Biotechnology @ibtcas.bsky.social · 12/01/2026
🧬 New Nucleic Acids Research paper: updated standards for validating RNA/DNA covalent geometry in PDB models. Introducing a 3-tier scheme: 🟢Preferred 🟡Allowed 🔴Of Concern — to reduce false alarms & improve future deposits. 🚀 doi.org/10.1093/nar/...
doi.org
New targets and procedures for validating the valence geometry of nucleic acid structures
Abstract. A Working Group consisting of the co-authors of this paper was established in 2020 to re-evaluate the standard valence geometry used for the vali
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Institute of Biotechnology @ibtcas.bsky.social · 09/01/2026
𝐄𝐱𝐜𝐢𝐭𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐨𝐮𝐫 𝐧𝐞𝐰 𝐍𝐮𝐜𝐥𝐞𝐢𝐜 𝐀𝐜𝐢𝐝𝐬 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐩𝐚𝐩𝐞𝐫 🧬 DNATCO v5.0 is a browser-based platform for 3D nucleic acid structure annotation + validation - fast, interactive, privacy-friendly. 📄 doi.org/10.1093/nar/... 🌐 dnatco.datmos.org
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Institute of Biotechnology @ibtcas.bsky.social · 06/01/2026
Congratulations to Prof. Mikael Kubista, recognized as a 2025 ScholarGPS Highly Ranked Scholar™ (Lifetime) — placing him in the top 0.05% of scholars worldwide. #30 in PCR and #41 in Gene expression profiling.
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Institute of Biotechnology @ibtcas.bsky.social · 31/12/2025
Happy New Year 2026 from IBT CAS ✨ Thanks to everyone we collaborate with — wishing you health, inspiration and exciting discoveries in 2026 🔬🤝
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Reposted by Institute of Biotechnology
Institute of Molecular Genetics @imgprague.bsky.social · 16/12/2025
📣We’re proud to announce the successful completion of our first Single-Cell RNA-seq course at the Institute of Molecular Genetics 📅 1–3 December 2025 🤝 In collaboration with ELIXIR CZ, @ibtcas.bsky.social and MetaCentrum
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Institute of Biotechnology @ibtcas.bsky.social · 15/12/2025
𝐆𝐫𝐞𝐚𝐭 𝐭𝐨 𝐬𝐞𝐞 𝐭𝐡𝐞 𝐉𝐮𝐧𝐢𝐨𝐫 𝐅𝐚𝐜𝐮𝐥𝐭𝐲 𝐢𝐧𝐢𝐭𝐢𝐚𝐭𝐢𝐯𝐞 𝐚𝐭 𝐂𝐡𝐚𝐫𝐥𝐞𝐬 𝐔𝐧𝐢𝐯𝐞𝐫𝐬𝐢𝐭𝐲 𝐟𝐞𝐚𝐭𝐮𝐫𝐞𝐝 𝐢𝐧 𝐍𝐚𝐭𝐮𝐫𝐞 👉 1url.cz/eJc6z Proud that our colleague @katerinarohlena.bsky.social contributed to early discussions and ideas around the #PIForum, which helped inspire initiatives that are now gaining international attention. 🚀
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Institute of Biotechnology @ibtcas.bsky.social · 28/11/2025
🔬 Our new study shows that mitochondrial respiration is essential for early tumour growth. Cancer cells can import mitochondria from nearby cells to restore pyrimidine synthesis and proliferate. A key vulnerability: DHODH — its loss fully blocks tumour growth. 📄 Cancer Research | 1url.cz/wJOxT
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Institute of Biotechnology @ibtcas.bsky.social · 27/11/2025
Naše kolegyně Aditi Chatterjee získala Pamětní grant Martiny Roeselové 2026! 🎉 Velká gratulace a díky @nf-iocbtech.bsky.social za podporu mladých vědců-rodičů. ❤️
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Institute of Biotechnology @ibtcas.bsky.social · 25/11/2025
🔬 𝐗𝐗𝐕𝐈𝐈𝐈. 𝐁𝐢𝐨𝐥𝐨𝐠𝐢𝐜𝐚𝐥 𝐃𝐚𝐲𝐬 opened with excellent talks and lively discussions. Congratulations to Prof. Jaroslav Petr on the Babák Medal. 👉 Join us again tomorrow. 1url.cz/gJOWh
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IOCB Foundation @iocbfoundation.cz · 24/11/2025
Kateřina Rohlenová @katerinarohlena.bsky.social z @ibtcas.bsky.social je uznávanou vědkyní v oblasti nádorové biologie. V roce 2023 získala podporu grantu MIT-Czech Republic IOCB Tech Foundation Seed Fund, díky němuž navázala spolupráci s MIT a nyní dokončuje přelomový článek o nádorových buňkách. ⤵️
Dr. Kateřina Rohlenová z Biotechnologického ústavu AV ČR/BIOCEV
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Institute of Biotechnology @ibtcas.bsky.social · 14/11/2025
🧬 The 4th Prague Symposium on Cancer Metabolism brought together experts to discuss new insights in tumor metabolism. We’re proud that two of our PhD students — 🏆 Pavel Jakoubě and 🏆 Mariia Hrysiuk — received a Best Poster Prize (2 of only 3 awarded). 👏 Congratulations!
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Reposted by Institute of Biotechnology
Akademie věd ČR @akademievedcr.bsky.social · 13/11/2025
🧫 Rychlá regenerace jater pod lupou vědců Více ⬇️ www.avcr.cz/cs/pro-media/tiskove-zpravy/Jatra-pri-regeneraci-pretvareji-toxicky-amoniak-na-latku-podporujici-rust/
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Institute of Biotechnology @ibtcas.bsky.social · 11/11/2025
💚 𝐓𝐰𝐨 𝐝𝐚𝐲𝐬 𝐟𝐮𝐥𝐥 𝐨𝐟 𝐜𝐮𝐫𝐢𝐨𝐬𝐢𝐭𝐲, 𝐬𝐜𝐢𝐞𝐧𝐜𝐞 𝐚𝐧𝐝 𝐠𝐫𝐞𝐚𝐭 𝐞𝐧𝐞𝐫𝐠𝐲! Almost 200 students explored our labs 🔬 Maybe some of them will be future scientists — or Nobel Prize winners. 😉
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Institute of Biotechnology @ibtcas.bsky.social · 30/10/2025
🏆 𝗧𝘄𝗼 𝗼𝗳 𝗼𝘂𝗿 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝘀𝘁𝘀 𝗵𝗮𝘃𝗲 𝗯𝗲𝗲𝗻 𝗮𝘄𝗮𝗿𝗱𝗲𝗱 𝗯𝘆 𝘁𝗵𝗲 @akademievedcr.bsky.social 🔬 Prof. Jiří Neužil – 𝗣𝗿𝗮𝗲𝗺𝗶𝘂𝗺 𝗔𝗰𝗮𝗱𝗲𝗺𝗶𝗮𝗲 𝟮𝟬𝟮𝟱 🧫 Dr. Aniruddha Mitra – 𝗟𝘂𝗺𝗶𝗻𝗮 𝗤𝘂𝗮𝗲𝗿𝘂𝗻𝘁𝘂𝗿 𝟮𝟬𝟮𝟱 💚 Congratulations on this exceptional success and recognition of their work! Read more 👉https://1url.cz/NJIjr
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Institute of Biotechnology @ibtcas.bsky.social · 06/10/2025
RNA is still waiting for its “AlphaFold moment.” 🔬✨ At IBT CAS we’re tackling this challenge head-on. Read more 👉 1url.cz/YJhsw
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Institute of Biotechnology @ibtcas.bsky.social · 02/10/2025
Don’t miss the opportunity!
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Institute of Biotechnology @ibtcas.bsky.social · 02/10/2025
🆕𝐍𝐞𝐰 𝐫𝐞𝐯𝐢𝐞𝐰 𝐟𝐫𝐨𝐦 𝐨𝐮𝐫 𝐋𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲 𝐨𝐟 𝐋𝐢𝐠𝐚𝐧𝐝 𝐄𝐧𝐠𝐢𝐧𝐞𝐞𝐫𝐢𝐧𝐠! Colleagues explored key drivers of metastatic non-small cell lung cancer (mNSCLC): 🔹 tumor heterogeneity 🔹 oncogenic drivers & resistance 🔹 immunosuppressive TME 📖 biosignaling.biomedcentral.com/articles/10....
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