Nickase and nuclease Prime Editors offer complementary routes for precise zebrafish genome editing, balancing accuracy for substitutions with efficiency for short insertions.

We are delighted to announce the winners of the Young Embryologist Network Image Competition held as part of the YEN 2026 Conference, which took place on

Developing embryos have a striking ability to buffer external and internal perturbations. A key example of this phenomenon across developing systems is successful organ formation even after substantia...

Neuronal migration is essential for establishing functional tissue architecture in the developing central nervous system. While cell-intrinsic mechanisms driving neuronal movement have been identified...

In Episode 5 of the Light-Sheet Chronicles, we spoke with Dr. Kate McDole (MRC LMB, Cambridge) and Dr. Jan Roden (Senior Software Architect, Bruker) about biomedical image analysis. What emerged was…

This Bruker webinar discusses how Bruker’s light-sheet, high-content screening, and big data management solutions create practical biological insights.

Browse through the gallery of the 9 images and vote for your favourite by Wednesday, 24 June 2026.

In Episode 5 of the Light-Sheet Chronicles, we spoke with Dr. Kate McDole (MRC LMB, Cambridge) and Dr. Jan Roden (Senior Software Architect, Bruker) about biomedical image analysis. What emerged was a...

A comparative analysis of cnidarian larval morphogenesis combined with active surface theory identifies a set of mesoscale mechanical modules that predict species-specific shapes. Manipulating these m...

YouTube video by Bruker Fluorescence Microscopy

Spider-like neurons finding their way: signposts for multipolar migration in the developing brain - News

Featured image with Jan Martinek - News

Bruker is pleased to announce the Bruker 2P Demo Day. This demonstration day will showcase the new miniature 2P microscope nVista 2P, for freely-moving imaging, and the Ultima 2Pplus for imaging in de...

How physically magnifying objects using a key ingredient in diapers has opened an unprecedented view of the microbial world.

Reliable and reproducible measurement of spatial resolution is essential for validating and comparing the performance of two-photon microscopy systems. We present fluorescent nanodiamonds as robust, photostable, reusable, and biocompatible probes for benchmarking spatial resolution. Owing to their nanoscale dimensions and stable fluorescence, nanodiamonds act as near-ideal point-like emitters, enabling accurate characterisation of the point spread function across varying imaging conditions. We demonstrate that nanodiamond-based phantoms serve as a reliable alternative to conventional fluorescent beads embedded in agarose, while at the same time offering advantages in stability and optical properties. Our results position nanodiamond phantoms as a next-generation calibration material that bridges ease of use and reproducibility, advancing quantitative imaging and cross-platform comparability in modern fluorescence microscopy. ### Competing Interest Statement The authors have declared no competing interest. Wellcome Trust, https://ror.org/029chgv08, Investigator Award in Science 220277/Z20/Z European Research Council, https://ror.org/0472cxd90, ERC-StG “NeuroVisEco” 677687, ERC AdG “Cones4Action” covered under the UK’s EPSRC guarantee scheme EP/Z533981/1 UK Research and Innovation, https://ror.org/001aqnf71, BBSRC, BB/R014817/1, BBSRC, BB/W013509/1 International Human Frontier Science Program Organization, https://ror.org/02ebx7v45, RGP001/2025 Leverhulme Trust, https://ror.org/012mzw131, PLP-2017-005, RPG-2021-026, RPG-2-23-042 Lister Institute of Preventive Medicine Gdańsk University of Technology, https://ror.org/006x4sc24, Nobelium DEC-4/1/2024/IDUB/I.1a/No, Platinum 1/1/2025/IDUB/I.1B/Pt

Bruker is pleased to announce the Bruker 2P Demo Day. This demonstration day will showcase the new miniature 2P microscope nVista 2P, for freely-moving imaging, and the Ultima 2Pplus for imaging in de...