Reposted by Jaroslav IchaNordenLab @nordenlab.bsky.social · 23/08/2026The reunion before the reunion… sometimes it is scary how fast time moves. What an amazing group of people I had the honor to help train and work with…. 0191
Jaroslav Icha @ichajaroslav.bsky.social · 26/07/2026 The special thing about this HIVE is that it won’t be storing and processing the usual fluorescence microscopy data. What is it you may ask? Stay tuned to learn more in the next months! I also caught very nice weather for evening jogging (Fig. 2-3). 000
Jaroslav Icha @ichajaroslav.bsky.social · 26/07/2026This week I visited Belgium for a Bruker Luxendo HIVE server installation (Fig. 1) with a detour to the Netherlands for some Bruker Fluorescence Microscopy lightsheet and superresolution microscopy conversations. 120
Jaroslav Icha @ichajaroslav.bsky.social · 12/07/2026We are happy to be part of this story with Bruker FM microscopes. There is one or two models that you still don't have, so just an idea for the next grant application ;-) Gotta catch 'em all! 000
Jaroslav Icha @ichajaroslav.bsky.social · 11/07/2026Thanks everyone for active participation and for many interesting conversations. We were also happy about everyone who passed by our booth, we will be in touch! 000
Jaroslav Icha @ichajaroslav.bsky.social · 11/07/2026 Zebrafish embryos and larvae are a perfect sample for our lightsheet and screening microscopes and the testament to that were the 70 participants in our workshop at the start of the conference. To be honest, that’s not normal, we are used to running a lot more "personalized" workshops 😉 100
Jaroslav Icha @ichajaroslav.bsky.social · 11/07/2026I'm sitting in the last session of the #EZM2026 conference and I'm grateful that I could participate on behalf of @brukercorporation.bsky.social Fluorescence Microscopy. Great trip to my academic past, I was relieved that I still more or less understand what people are working on. 150
Reposted by Jaroslav IchaPauli Group (posts by Andi Pauli) @pauligroup.bsky.social · 07/07/2026The #EZM2026 (European Zebrafish Society @ezsociety.bsky.social meeting) is in full swing! More than 500 (not only zebra-)fish researchers from all over the world gather here in Vienna for the next 5 days to discuss science, exchange ideas and make new connections. #Fish #Zebrafish #Friends 1298
Reposted by Jaroslav IchaSteffen Scholpp @scholpplab.bsky.social · 08/07/2026No better way to head to #EZM2026 than with a freshly published success! Our eLife paper is now out: elifesciences.org/articles/107.... We show optimised prime editing in zebrafish for precise DNA substitutions and insertions. Huge thanks to the fantastic team #Zebrafish #GenomeEditing #eLifeelifesciences.orgOptimised genome editing for precise DNA insertion and substitution using prime editors in zebrafishNickase and nuclease Prime Editors offer complementary routes for precise zebrafish genome editing, balancing accuracy for substitutions with efficiency for short insertions. 1275
Reposted by Jaroslav IchaJaroslav Icha @ichajaroslav.bsky.social · 06/07/2026Come to the Bruker Fluorescence Microscopy booth at the #EZM2026 zebrafish meeting in Vienna this week to learn how to capture movies like this one below in high throughput. 051
Reposted by Jaroslav IchaYoung Embryologist Network @yen-network.bsky.social · 06/07/2026Celebrate #ModelMonday with all these amazing images of embryogenesis! thenode.biologists.com/results-of-t...thenode.biologists.comResults of the YEN 2026 Image Competition - the NodeWe are delighted to announce the winners of the Young Embryologist Network Image Competition held as part of the YEN 2026 Conference, which took place on 1139
Reposted by Jaroslav IchaYoung Embryologist Network @yen-network.bsky.social · 06/07/2026We are excited to announce the results of the YEN 2026 Image Competition! Thanks to all who submitted an entry. This year amazing work has been shared with us complementing our perspectives talks on art+science. We congratulate the winners of the YEN and public votes! #yen2026 #yenimagecompetition 13311
Jaroslav Icha @ichajaroslav.bsky.social · 06/07/2026Come to the Bruker Fluorescence Microscopy booth at the #EZM2026 zebrafish meeting in Vienna this week to learn how to capture movies like this one below in high throughput. 051
Reposted by Jaroslav IchaNordenLab @nordenlab.bsky.social · 03/07/2026#2 Close collaboration with @rocha-lab.bsky.social across institutes. @catfigueiredo.bsky.social shows that neurogenic progenitors in the developing retina can respond to cell death with an unexpected self-renewing division. I am sure Mauricio has more to say :-). www.biorxiv.org/content/10.6...biorxiv.orgApoptosis-induced self-renewal of neurogenic progenitors safeguards retinal development against extensive cell lossDeveloping embryos have a striking ability to buffer external and internal perturbations. A key example of this phenomenon across developing systems is successful organ formation even after substantia... 03210
Reposted by Jaroslav IchaNordenLab @nordenlab.bsky.social · 03/07/2026We are trying for a hattrick this month and two out of three are out: #1 Great work by Margarida Cruz et al. showing that tissue context in addition to cell intrinsic programs can determine migration mode of neurons. Retinal Bipolar Cells as an example. Check it out! www.biorxiv.org/content/10.6...biorxiv.orgTissue lamination state switches neuronal translocation from active to passive in the vertebrate retinaNeuronal migration is essential for establishing functional tissue architecture in the developing central nervous system. While cell-intrinsic mechanisms driving neuronal movement have been identified... 1256
Jaroslav Icha @ichajaroslav.bsky.social · 01/07/2026🔬 lightsheet (Trulive, Papilio) - time lapse imaging at high resolution with low phototoxicity 🔬 screening (Acquifer IM) - scale up your screening or time lapse assays 🔬 data management (HIVE) - process and store all the big datasets coming from the microscopes (Bruker but also other manufacturers) 000
Jaroslav Icha @ichajaroslav.bsky.social · 01/07/2026I really look forward to next week in Vienna #EZM2026. Happy to meet all the researchers using zebrafish in their research. I have been in touch with so many of you about the Bruker Luxendo microscopes. It will be good to meet in person! 110
Reposted by Jaroslav IchaPhil Abitua @ohnolog.bsky.social · 30/06/2026Annual killifish continue to surprise us: they make neutrophils before almost every other cell type, even before gastrulation. Neutrophils usually arise from the lateral plate mesoderm (forming in cyan), but in killifish they are already patrolling around the embryo in gold. tinyurl.com/killiphil 720357
Reposted by Jaroslav IchaElisabeth Kugler @kuglerelisabeth.bsky.social · 30/06/2026🔬 Innovation happens at the intersection of engineering and biology • Dr Kate McDole shares how advanced imaging reveals previously hidden dynamics in early mouse development. • Dr Jan Roden shares insights into the engineering and software that make such visualisation possible. 1/2bruker.comEpisode 5: Challenges of Biomedical Image Analysis in Light-Sheet MicroscopyIn Episode 5 of the Light-Sheet Chronicles, we spoke with Dr. Kate McDole (MRC LMB, Cambridge) and Dr. Jan Roden (Senior Software Architect, Bruker) about biomedical image analysis. What emerged was… 153
Reposted by Jaroslav IchaPhysics of Life Dresden @poldresden.bsky.social · 30/06/2026🤔 How do organs measure and control their size? 🐟 The Mateus Lab @ritamateus.bsky.social at PoL & @mpi-cbg.de use #zebrafish to understand how organs form the right size and shape, at the right time, during development or regeneration. Learn more in our new video 👉 youtu.be/L7XUfk0s51E 0243
Jaroslav Icha @ichajaroslav.bsky.social · 24/06/2026Good to see this superres volumetric 3D dataset from the Bruker Fluorescence Microscopy VXL microscope! DNA paint of a full cell volume? No problem with this new kit. 000
Reposted by Jaroslav IchaMassive Photonics @massivephotonics.bsky.social · 24/06/2026𝗩𝗶𝗱𝗲𝗼: B cell mitochondria imaged across an entire 10.5 µm cell volume, localization precision ~11 nm. 001
Reposted by Jaroslav IchaMassive Photonics @massivephotonics.bsky.social · 24/06/2026Our optimized imager strands & kits enable robust DNA-PAINT via epifluorescence illumination. Image entire cell volumes at nanoscale resolution via z-stacks. ✅ Full volumetric imaging — no TIRF/HILO constraints ✅ Compatible with Bruker Vutara VXL out of the box ✅ Optimized imagers for EPI DNA-PAINT 101
Jaroslav Icha @ichajaroslav.bsky.social · 24/06/2026I'll be at the Dutch Neuroscience Meeting #DNM26. Happy to talk to anyone interested in microscopy. 🔬 multiphoton for the challenging in vivo experiments - optogenetics, voltage imaging, large field of view imaging 🔬 miniscopes for imaging in freely moving animals 🔬 lightsheet for the cleared brains 020
Reposted by Jaroslav IchaMwahahahahahadScientist @mads100tist.bsky.social · 10/06/2026Look, people. We have superb keynotes, we are giving prizes, we are giving postdocs a megaphone to tell everyone why they should be hired. This is the meeting to be at. Sign up, join us, and have the time of your life while discussing science with people that know where the cleithrum is🐟🧪 12511
Jaroslav Icha @ichajaroslav.bsky.social · 10/06/2026If you think about moving towards live imaging and higher throughputs with your 3D samples, this event can be a good start! It will cover @brukercorporation.bsky.social Luxendo #lightsheet microscopes as well as the Acquifer IM screening microscope and #HIVE server www.bruker.com/en/news-and-...bruker.comBruker Fluorescence Microscopy Solutions: Automated Imaging and Light-Sheet MicroscopyThis Bruker webinar discusses how Bruker’s light-sheet, high-content screening, and big data management solutions create practical biological insights. 020
Reposted by Jaroslav Ichathe Node @the-node.bsky.social · 10/06/2026Vote for a @dev-journal.bsky.social cover from the 2025 Quintay International Course on Developmental Biology We’re excited to launch a cover competition to select an image from the 2025 cohort of @devbioquintay.bsky.social. Voting closes on 24 June 2026. thenode.biologists.com/vote-for-a-d...thenode.biologists.comVote for a Development cover from the Quintay International Course on Developmental Biology - the NodeBrowse through the gallery of the 9 images and vote for your favourite by Wednesday, 24 June 2026. 33622
Jaroslav Icha @ichajaroslav.bsky.social · 08/06/2026A next episode of the Bruker Fluorescence Microscopy #lightsheet podcast digging deep into image registration in light-sheet microscopy. www.bruker.com/en/products-...bruker.comEpisode 5: Challenges of Biomedical Image Analysis in Light-Sheet MicroscopyIn Episode 5 of the Light-Sheet Chronicles, we spoke with Dr. Kate McDole (MRC LMB, Cambridge) and Dr. Jan Roden (Senior Software Architect, Bruker) about biomedical image analysis. What emerged was a... 040
Jaroslav Icha @ichajaroslav.bsky.social · 20/05/2026📌 lightsheet for your organoid time-lapses or cleared tissues 📌 multiphoton for deep tissue imaging, neurooncology 📌 superresolution for the fine details in 3D 📌 screening for imaging your spheroids or xenografts in high throughput I'm happy to schedule a meeting! 000
Jaroslav Icha @ichajaroslav.bsky.social · 20/05/2026Next week Wednesday-Friday I will be in Wroclaw mainly to attend an oncology conference at Łukasiewicz - PORT. I will be there with our distributor Labsoft to talk about Bruker Fluorescence Microscopy microscopes to whoever is willing to listen :-) 100
Jaroslav Icha @ichajaroslav.bsky.social · 18/05/2026The installation went smoothly thanks to the one and only Steven Trier. I would also like to thank Labsoft (Grzegorz Szumilas, Adam Rybak, Michał Czaja), our local partner, for all the help during the whole process. 000
Jaroslav Icha @ichajaroslav.bsky.social · 18/05/2026I hope that the users from Bartosz Pomierny, Mateusz Kucharczyk and other labs in Krakow will capture some exciting data and execute experiments that were not possible to do before. 100
Jaroslav Icha @ichajaroslav.bsky.social · 18/05/2026This setup for advanced neuroscience experiments will allow, besides the obvious deep tissue imaging with large field of view, also 2P and 1P photomanipulation as well as voltage and blood flow imaging with our #Optovolt module. 100
Jaroslav Icha @ichajaroslav.bsky.social · 18/05/2026Last week we installed the Bruker Fluorescence Microscopy Ultima 2P Plus multiphoton in Krakow, Poland at the Uniwersytet Jagielloński-Collegium Medicum. How the week ended vs. how it started 👇 120
Jaroslav Icha @ichajaroslav.bsky.social · 19/04/202621st century dev bio at its best! I can't help but point out that not one but two Bruker microscopes (Acquifer IM, MuVi) were used for gentle&long term time lapse imaging of developing Nematostella here. No need to mount your invertebrate (cnidaria, planaria, crustaceans), we can do the time lapse! 051
Reposted by Jaroslav IchaAissam Ikmi @aikmi.bsky.social · 18/04/2026Now published. Congrats to Soham and all co-authors! www.science.org/doi/10.1126/.... @embl.orgscience.orgScience | AAAS 25320
Jaroslav Icha @ichajaroslav.bsky.social · 14/04/2026program and registration: www.bruker.com/en/news-and-... Perhaps not the most convenient time for EU, where most people, who will see this post, live. However, one can always go back to the recordings. 000
Jaroslav Icha @ichajaroslav.bsky.social · 14/04/2026The relevant technologies featured are our benchtop multiphoton microscope Ultima 2P Plus, the range of Inscopix miniscopes and the superresolution Vutara VXL microscope. 100
Jaroslav Icha @ichajaroslav.bsky.social · 14/04/2026Like last year, we are running an online Bruker Fluorescence Microscopy neuroscience miniconference. It is focused on the actual science one can do with our microscopes presented by researchers, not sales presentations. 110
Reposted by Jaroslav IchaStefan Terjung @stefanterjung.bsky.social · 14/04/2026We are looking for an experienced light microscopy specialist, motivated to support our users in the Advanced Light Microscopy Facility at EMBL Heidelberg. embl.wd103.myworkdayjobs.com/en-US/EMBL/j... -closing date 11 May 2026 @eurobioimaging.bsky.social @globalbioimaging.bsky.socialembl.wd103.myworkdayjobs.com 03535
Jaroslav Icha @ichajaroslav.bsky.social · 02/04/2026Don't miss it! We will present several different imaging modalities popular among zebrafish researchers #lightsheet #HCS #screening 000
Jaroslav Icha @ichajaroslav.bsky.social · 02/04/2026I suppose most EU zebrafish researchers will attend European zebrafish meeting in July in Vienna #EZM2026. It is going to be a great event like the previous one in Krakow. Important note for you: Come early, already on 6th in the evening. The conference starts with Bruker Luxendo workshop on 7th. 110
Reposted by Jaroslav IchaAissam Ikmi @aikmi.bsky.social · 20/03/2026Our study on shape diversity in cnidarians is now published. The final version includes extensive new data that substantially extend the original bioRxiv preprint. Congrats to everyone who contributed to this work! www.cell.com/cell/fulltex... @embl.orgcell.comDeciphering mechanical determinants of morphological evolutionA comparative analysis of cnidarian larval morphogenesis combined with active surface theory identifies a set of mesoscale mechanical modules that predict species-specific shapes. Manipulating these m... 514164
Jaroslav Icha @ichajaroslav.bsky.social · 18/03/2026Interesting points: 📌max projection on the fly to see what's going on 📌data compression helps hugely (zeroing the background, especially if your sample takes up only a small part of FOV) 📌not only processing, also "just" visualization of a 4D lightsheet dataset is non-trivial So, go and listen. 000
Jaroslav Icha @ichajaroslav.bsky.social · 18/03/2026Whoever tried some lightsheet microscopy knows that image acquisition is the fun easy part. The real challenge comes later. This @brukercorporation.bsky.social Luxendo podcast episode touches on the real challenges. www.youtube.com/watch?v=tAjl...youtube.comImage Analysis in Light-Sheet Microscopy: Big Data Processing, Handling, and StorageYouTube video by Bruker Fluorescence Microscopy 182
Reposted by Jaroslav IchaFocalPlane @focalplane.bsky.social · 11/03/2026📢New behind the paper story Using the #zebrafish retina as a model, Jaakko Lehtimäki @jalehtimaki.bsky.social, Caren Norden @nordenlab.bsky.social & team dissect multipolar migration in the developing brain. In this post, Jaakko takes us through their research.focalplane.biologists.comSpider-like neurons finding their way: signposts for multipolar migration in the developing brain - FocalPlaneSpider-like neurons finding their way: signposts for multipolar migration in the developing brain - News 0235
Reposted by Jaroslav IchaZebrafish Rock! 🎃 @zebrafishrock.bsky.social · 11/03/2026Lovely perspective on the recent paper by @nordenlab.bsky.social, written by first-author (and former Postdoc) @jalehtimaki.bsky.social 🐟 🔗 to feature: focalplane.biologists.com/2026/03/11/s... 🔗 to original research paper ICYMI: www.sciencedirect.com/science/arti... 031
Reposted by Jaroslav IchaZebrafish Rock! 🎃 @zebrafishrock.bsky.social · 12/03/2026New work from Metz Lab @ribesresearch.bsky.social 🐟 🔗 to paper: journals.biologists.com/jeb/article/... 041