Reposted by Ian Hussey
🍫 or 💩? About the effect size reported in a trial that shaped the estimated effect of fluoxetine in meta-analyses of pediatric depression, my stellar co-author @ploederl.bsky.social says: “It’s the kind of effect size you only get if you ask people whether they prefer chocolate or faeces.” 👇👇👇
nature.com
Prozac use for childhood depression skewed by single flawed medical trial
One small study in Iran swayed meta-analyses in favour of antidepressant use in children, researchers say.