Cell-based models of the human cortex transplanted into mice produce neurons that are inaccessible in vitro, and could enable scientists to link brain injury to behaviour.

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The development of two medical AI assistants highlights an unnerving challenge: as the technology races ahead, what is the best way to evaluate what works?

Spatially resolved transcriptomic technologies continue to enhance understanding of development and disease through a feedback loop involving academia and industry.

Spatially resolved transcriptomic technologies continue to enhance understanding of development and disease through a feedback loop involving academia and industry.

One in six Internet-using adolescents in parts of Africa and Asia faced technology-facilitated sexual abuse in 2020–21. As digital access expands globally, better protection is crucial.

A systematic assessment of health-related queries to a chatbot powered by artificial intelligence highlights shortfalls in health-care provision and the responsibilities of AI companies.

Integration of gene expression data from multiple tissues across four mammalian species reveals conserved transcriptomic signatures of mammalian ageing and mortality and uncovers the modular...

A system of protein binders directs energy-generating organelles to targeted cells, potentially improving ways to treat mitochondrial dysfunction.

Neuroscientists have created a continuous atlas showing how patterns of functional connectivity between brain regions change from birth to old age.

MicroRNAs control gene expression by modulating the output and stability of messenger RNAs. How are these crucial regulators kept in check?

In a dividing cell, chromosome pairs are pulled apart thanks to attachment sites called centromeres. Yeast genomes reveal key steps in how centromeres have evolved. In a dividing cell, chromosome pairs are pulled apart thanks to attachment sites called centromeres. Yeast genomes reveal key steps in how centromeres have evolved.

Viral DNA that is usually dismissed when sequencing the human genome could help to uncover useful information about complex diseases.

In life-threatening sepsis, the same signalling pathway that protects young mice from succumbing to organ dysfunction exacerbates damage and lethality in older animals.

A study in Australia supports genetic screening in young adults before symptoms show, but the generalizability and cost–benefit ratios need to be examined in other settings.

Unexpected behaviours in G proteins could be exploited to design next-generation opioid drugs that provide stronger, longer-lasting pain relief.

Conversations with AI can sway people’s political views. Concerningly, a chatbot’s facts are not always accurate, especially when it supports right-wing positions.

Over 20 species of geographically and phylogenetically diverse bird species produce convergent whining vocalizations towards their respective brood parasites. Model presentation and playback experimen...

Lithium in the brain has been found to protect against cognitive decline. Restoring lost lithium could be a new angle from which to tackle Alzheimer’s disease.

Research shows that jargon can make weak explanations feel complete by masking their gaps. What can experts do to communicate science effectively to laypeople?

A gender gap in mathematical ability arises shortly after children begin school — irrespective of the type of school they attend and their socio-economic background.

A pangenome for the genus Solanum.

A modified CB1-receptor agonist for analgesia without adverse effects.

Implementing a performance-rating system with a two-point scale instead of a five-point scale could be an easy way to temper racial prejudices and tangibly improve income equality for workers from under-represented groups. Switch in performance-rating system could reduce racial pay gap.

Transcriptionally similar neurons can be functionally diverse.

Ancient genomes from Ukraine and Russia reveal Yamna origins.

Cracks in Greenland's glaciers deepened by climate change.