Rebecca Hendrickson MD, PhD @hendricksonmd.bsky.social · 02/02/2026But, this first step towards just changing the way we think and talk about these types of experiences and where they come from, is by itself one I believe to be really important. 020
Rebecca Hendrickson MD, PhD @hendricksonmd.bsky.social · 02/02/2026Currently, we're trying to work out individualized tests of some of the specific mechanisms that may be causing both the physical and mental/cognitive symptoms - and that we might be able to treat directly. 120
Rebecca Hendrickson MD, PhD @hendricksonmd.bsky.social · 02/02/2026That people with a higher burden of past trauma exposure report more persistent autonomic symptoms after COVID-19 or other viral infections, even adjusting for symptoms of PTSD or similar symptoms prior to COVID. 110
Rebecca Hendrickson MD, PhD @hendricksonmd.bsky.social · 02/02/2026And while these changes may interact and reinforce each other, they can both be real, without one necessarily being the "real" or primary effect. This paper tests a relationship we've been seeing in our clinical work for years but that hasn't been well studied or recognized: 110
Rebecca Hendrickson MD, PhD @hendricksonmd.bsky.social · 02/02/2026Instead, we need to be able to consider how both psychological stress and trauma and physiologic stressors (e.g. COVID infection, TBI, etc) can both turn on changes in our brain and body's stress-threat response systems that can affect both physical and mental health. 110
Rebecca Hendrickson MD, PhD @hendricksonmd.bsky.social · 02/02/2026But, that's not nec'ly how it works. Treating PTSD, anxiety etc can help substantially with physical symptoms & I will advocate for effective MH treatment all day long. But it doesn't mean that your physiology is now the same as if it hadn't happened - & if it's not, you're just doing it wrong. 120
Rebecca Hendrickson MD, PhD @hendricksonmd.bsky.social · 02/02/2026eg, so many people I see with PTSD have sig physical symptoms - & they have a list of diagnoses (hypertension, IBS, heart palpitations or POTS, etc), or there's an assumption that if they treat their mental health diagnoses and "manage their stress better" then their physical symptoms will be gone. 110
Rebecca Hendrickson MD, PhD @hendricksonmd.bsky.social · 02/02/2026But even when our medical system recognizes that physical and mental/cognitive symptoms are connected, it's assumed that either the physical symptoms are the "real" and primary experience and the psychiatric symptoms are "secondary", or visa versa. 110
Rebecca Hendrickson MD, PhD @hendricksonmd.bsky.social · 02/02/2026It's obvious to most people that you can experience physical symptoms after a stressful event or a trauma - and that physical illness can cause anxiety, insomnia, cognitive changes, etc. 110
Rebecca Hendrickson MD, PhD @hendricksonmd.bsky.social · 02/02/2026tl;dr: Our medical system constantly wants to silo physical and mental health, but they are fundamentally intertwined more than we know how to talk about - and things that cause both physical stress and psychological trauma can interact with each other. journals.sagepub.com/doi/10.1177/...journals.sagepub.comImpact of Prior History of Traumatic Stress on Autonomic and Multi-System Symptoms Following COVID-19 Infection - Rebecca C. Hendrickson, Christine S. Cheah, Marlene L. Tai, Kathleen F. Pagulayan, Kat...Background Persistent symptoms of autonomic dysregulation are common after COVID-19 infection and may result from alterations in central and/or peripheral auton... 110
Rebecca Hendrickson MD, PhD @hendricksonmd.bsky.social · 02/02/2026I was on NPR last week talking about a new publication that is really important to me - part of our larger effort to change the way we think and talk about both mental and physical health, and how they relate to each other, after stress and trauma. www.knkx.org/2026-01-28/u...knkx.orgUW study shows possible connection between trauma and long COVIDSome people with long COVID may experience certain symptoms — sudden blood pressure spikes or nausea, for instance — due to stress or trauma. 152
Reposted by Rebecca Hendrickson MD, PhDUW Infectious Disease Fellowship Program @uwidfellowship.bsky.social · 22/11/2025#IDSky First person with H5N5 has died :( 14647
Reposted by Rebecca Hendrickson MD, PhDJohn Scott-Railton @jsrailton.bsky.social · 02/09/202510/ After 14 years of working on this topic, I tell you this with confidence: Highly invasive mercenary spyware is a power abuse machine. It's incompatible with Americans constitutional rights and freedoms. And our legal system and civil society is not prepared for the next chapter. 219060
Reposted by Rebecca Hendrickson MD, PhDCarl T. Bergstrom @carlbergstrom.com · 19/04/20251. The DOJ has sent threatening letters to several medical journals, focused around whether these journals are spreading misinformation that harms the American people and suppressing alternative viewpoints. I study how the norms and institutions of science facilitate discovery and self-correction.nytimes.comTrump-Allied Prosecutor Sends Letters to Medical Journals Alleging Bias (Gift Article)An interim U.S. attorney is demanding information about the selection of research articles and the role of N.I.H. Experts worry this will have a chilling effect on publications. 51938405
Reposted by Rebecca Hendrickson MD, PhDHarold D. Foster @mg0blue1976.bsky.social · 06/04/2025We opted to join Bainbridge Island’s rally, which had well over 1K+ protestors. One of the speakers we heard was a Japanese American internee who, in 1942, was removed from Bainbridge Island to an internment camp with her family. Her closing words: “Never again is now.” 17014
Reposted by Rebecca Hendrickson MD, PhDDan Semenza @daniel-semenza.bsky.social · 25/03/2025Defensive gun use is rare but gun violence exposure is far too common. Check out this interview re: our new study in @jama.com Open from @mikeanestis.bsky.social. Watch the full interview for important thoughts on very real threats to our work @ the GVRC. www.njspotlightnews.org/video/rutger...njspotlightnews.orgRutgers study debunks argument that guns make people safer | Video | NJ Spotlight NewsInterview: Mike Anestis, executive director of New Jersey Gun Violence Research Center 43720
Reposted by Rebecca Hendrickson MD, PhDKatharine Hayhoe @katharinehayhoe.com · 15/03/2025I’m am adaptation scientist and here’s what I had to say about this—many years ago already.theguardian.comWe cannot adapt our way out of climate crisis, warns leading scientistKatharine Hayhoe says the world is heading for dangers people have not seen in 10,000 years of civilisation 20555184
Reposted by Rebecca Hendrickson MD, PhDDave Levitan @davelevitan.bsky.social · 08/03/2025Mandatory high school civics class that isn’t just like “how a bill becomes law” or whatever but also “how NOAA powers your phone’s weather app” and “NIH helped make your asthma inhaler” 8341301005
Reposted by Rebecca Hendrickson MD, PhDSenator Patty Murray @murray.senate.gov · 05/03/2025Trump is LYING about Social Security right now. Elon Musk called Social Security a "Ponzi scheme." They are cutting staff drastically at Social Security to make it harder for seniors to get their benefits. These corrupt billionaires need to keep their HANDS OFF Social Security! 48738187
Reposted by Rebecca Hendrickson MD, PhDKatharine Hayhoe @katharinehayhoe.com · 30/01/2025On climate, did you know that only 11% of people in the US (and even smaller percentages in Canada, the UK, Australia and beyond) are dismissive? Yet because their voices are so loud and persistent, people often think they’re 50%. This is why I advocate so strongly for using YOUR voice! 11932299
Reposted by Rebecca Hendrickson MD, PhDKatharine Hayhoe @katharinehayhoe.com · 19/01/2025Researchers found 15 people in Kansas City who had changed their mind about climate change, and asked them why. Fascinating! link.springer.com/article/10.1... 411019300
Reposted by Rebecca Hendrickson MD, PhDJatin Nagpal @jatinnagpal.bsky.social · 18/01/2025Mechanosensation of the heart and gut elicits hypometabolism and vigilance in mice | Nature Metabolism www.nature.com/articles/s42...nature.comMechanosensation of the heart and gut elicits hypometabolism and vigilance in mice - Nature MetabolismScott, Tan et al. characterize the neural circuits that link mechanic stimuli in the heart and gut with whole-body energy homeostasis and vigilance. 021
Reposted by Rebecca Hendrickson MD, PhDLizzie Manning @drlizziemanning.bsky.social · 17/01/2025Exciting new data on psilocybin effects on hypothalamic CRH neurons @gergelyturi.bsky.social Tamas Füzesi & @stressynomics.bsky.social www.biorxiv.org/content/10.1...biorxiv.orgPsilocybin induces sex- and context-specific recruitment of the stress axisPsychedelics have reemerged as potential treatments for mental health disorders, yet their impact on stress-related brain regions remains poorly understood. Here, we provide the first real-time, in vi... 0101
Reposted by Rebecca Hendrickson MD, PhDEric Topol @erictopol.bsky.social · 14/01/2025Dirty air, dementia, and other adverse brain effects www.nature.com/articles/d41... new Feature @nature.com open-access 912840708
Reposted by Rebecca Hendrickson MD, PhDDan Semenza @daniel-semenza.bsky.social · 14/01/2025New study out now in SS&M from our team @njgvrc.bsky.social! Both frequency + recency of gun violence exposure influence mental health and suicide. More national evidence of the extensive toll that gun violence takes on our collective health and well-being. www.sciencedirect.com/science/arti...sciencedirect.comFrequency, recency, and variety of gun violence exposure: Implications for mental health and suicide among US adultsGun violence exposure (GVE) is a pervasive public health issue in the United States, with significant implications for mental health. This study exami… 0167
Reposted by Rebecca Hendrickson MD, PhDMick Craig @mickcraig.bsky.social · 11/01/2025My new year's resolution was to work through the pile of almost-finished papers so... #PrePrintAlert #NeuroSkyence. This is an update to one we put out late 2021, which got delayed with Lilya (lead author) going on maternity leave (yay, lab baby! 🥰). A brief 🧵 1/ www.biorxiv.org/content/10.1...biorxiv.orgHippocampus does not appear to be a major target of thalamic nucleus reuniensThe prefrontal - hippocampal - entorhinal system is perhaps the most widely-studied circuit in cognitive and systems neuroscience, due to its role in supporting cognitive functions such as working mem... 1247
Reposted by Rebecca Hendrickson MD, PhDJoeri Bordes @joeribordes.bsky.social · 20/12/2024We've uncovered sex-specific effects of early-life stress (ELS) exposure on fear memory, HPA-axis regulation, and brain metabolism🧠. Unsupervised clustering shows that fear responses are more than only freezing. @mathiasvschmidt.bsky.social nature.com/articles/s42... Highlights in thread👇nature.comSex-specific fear acquisition following early life stress is linked to amygdala and hippocampal purine and glutamate metabolism - Communications BiologyThis study models early life stress (ELS) to observe sex-specific effects on fear memory formation using innovative unsupervised classification together with cellular metabolism alterations in key str... 7217
Reposted by Rebecca Hendrickson MD, PhDGavin Schmidt @climateofgavin.bsky.social · 10/01/2025All surface temperature products for 2024 are now live. All show 2024 is the warmest year (very clearly). The estimates of the change since the pre-industrial (1850-1900) are more uncertain but range from 1.46 to 1.62ºC. It is therefore *likely* this was the first year that exceeded 1.5ºC. 21509239
Reposted by Rebecca Hendrickson MD, PhDDr. Nikki Crowley @nicoleacrowley.bsky.social · 10/01/2025The Conversation asked me to share my thoughts on the new U.S. Surgeon General Advisory around alcohol and cancer & to break down some of the science in an accessible way. Check it out here: theconversation.com/even-1-drink...theconversation.comEven 1 drink a day elevates your cancer risk – an expert on how alcohol affects the body breaks down a new government reportThe government linked alcohol with seven types of cancers, prompting the US surgeon general to call for warning labels on beer, wine and liquor. 42411
Reposted by Rebecca Hendrickson MD, PhDNatalie hauglund @nataliehauglund.bsky.social · 10/01/2025Out in @cellcellpress.bsky.social ! We show that oscillations in norepinephrine and cerebral blood volume are the missing pieces that link NREM sleep to clearance of waste from the brain 🧠💤 www.cell.com/cell/fulltex...cell.comNorepinephrine-mediated slow vasomotion drives glymphatic clearance during sleepNorepinephrine oscillations during NREM sleep drive synchronized changes in cerebral blood volume and cerebrospinal fluid, promoting glymphatic clearance. Optogenetic and pharmacological manipulations confirm that vasomotion, regulated by norepinephrine, acts as a pump for brain fluid transport. 2134
Reposted by Rebecca Hendrickson MD, PhDKatharine Hayhoe @katharinehayhoe.com · 09/01/2025I define hope as the belief that our actions can make a difference. For me, it's not an emotion but rather a daily practice. Every week I share good news of climate solutions, not-so-good news on how climate change is affecting our lives, and something concrete we can do about it. Subscribe here:talkingclimate.caTalking Climate | Katharine Hayhoe | SubstackSubscribe to Katharine's newsletter for a clear-eyed and hopeful look at climate science and solutions. Receive weekly climate updates, good climate news, event information, ideas on things to do and ... 1117051
Reposted by Rebecca Hendrickson MD, PhDWaggoner Lab @labwaggoner.bsky.social · 08/01/2025Norepinephrine-mediated slow vasomotion drives glymphatic clearance during sleep @cellcellpress.bsky.social @nataliehauglund.bsky.social www.cell.com/cell/fulltex... 062
Reposted by Rebecca Hendrickson MD, PhDKatharine Hayhoe @katharinehayhoe.com · 08/01/2025Climate change is creating warmer, drier conditions that cause fire seasons in some regions like western North America to last longer and be more active. Read more:nature.orgYes, Climate Change is Raising the Risks—and Stakes—of Extreme WildfiresRising temperatures, parched forests, and shifting precipitation patterns are fueling severe wildfires with unprecedented impacts. There is still time to act. 9533217
Reposted by Rebecca Hendrickson MD, PhDDeb Chachra @debcha.bsky.social · 09/01/2025Occasional reminder that there’s no, “it’s too late, its over” for anthropogenic climate change. Every molecule of CO2 that doesn’t go into the atmosphere makes a difference. Preventing 0.1 degree of warming makes a difference. Every bit of climate resilience we build together makes a difference. 4343607210385
Reposted by Rebecca Hendrickson MD, PhDMax Kennerly @maxkennerly.bsky.social · 08/01/2025To everyone's surprise, it turns out that attaching a money-sucking machine to a hospital system makes it worse.nbcnews.comPrivate equity reduces patient care while enriching investors, Senate report findsThe bipartisan investigation of hospital systems purchased by Apollo Global Management and Leonard Green & Partners reinforced the findings of past academic research. 37999033404
Reposted by Rebecca Hendrickson MD, PhDScience Magazine @science.org · 07/01/2025Light can influence metabolism independent of the circadian clock, according to a new #ScienceAdvances study in mice. Learn more: scim.ag/3DIu7bPscim.agLight modulates glucose and lipid homeostasis via the sympathetic nervous systemLight exerts circadian-independent effects on glucose and lipid metabolism. 17517
Rebecca Hendrickson MD, PhD @hendricksonmd.bsky.social · 08/01/2025The violence point is interesting to me.... 010
Rebecca Hendrickson MD, PhD @hendricksonmd.bsky.social · 07/01/2025Similarly, GBD is by no means a perfect measure either - bc it emphasizes years lost or lived with disability it weights dementia much lower in impact than most would who've lived its impact on a family member or with the possibility of it hanging over them. 100
Rebecca Hendrickson MD, PhD @hendricksonmd.bsky.social · 07/01/2025This is interesting but in some ways misleading. Eg, by separating "depression" from "mdd" (and also andedonia) it makes it look like we're overemphasizing one and underemphasizing another, but most of the foundational work is the same. 1/2 100
Reposted by Rebecca Hendrickson MD, PhDUsha Lee McFarling @usha.bsky.social · 06/01/2025Just published: FDA puts out new guidelines, include testing on more subjects with all ranges of skin colors, to improve the accuracy of pulse oximeters in people with darker skin. Said one source: FDA is now really clearly addressing the issue of racial bias. www.statnews.com/2025/01/06/p...statnews.comFDA releases long-awaited guidance to improve accuracy of pulse oximeters for all skin tonesThe FDA released long-awaited guidance proposing how manufacturers should test and label pulse oximeters 0168
Rebecca Hendrickson MD, PhD @hendricksonmd.bsky.social · 06/01/2025This isn't really new. Take SSRIs: there's a long history of work suggesting a portion of their effect comes from impacts on BDNF/neuroplasticity. We talk about how this may increase your ability to respond in a new way to your environment. Why wouldn't we assume interaction is likely? 000
Rebecca Hendrickson MD, PhD @hendricksonmd.bsky.social · 06/01/2025The idea that we need to shift from assuming pharmacotherapies have effects that are separable from the context in which they're taken is one I agree with. In fact, the significant majority of the medications I prescribe there is evidence to suggest important drug-context interactions. 140
Reposted by Rebecca Hendrickson MD, PhDMax Wolff @trpwolff.bsky.social · 04/01/2025I encourage everyone to read through Compass' latest description of their "psychological support" model. If this is not in fact psychotherapy, then nothing is. Ironically, this is most evident whenever the authors apparently aim to differentiate their model from (their idea of) psychotherapy, e.g.: 1145
Reposted by Rebecca Hendrickson MD, PhDChristian Staehr @chrstaehr.bsky.social · 02/01/2025🚨 Breaking #Physiology news: Spinal arteries dilate in response to #noradrenaline! Our new study (www.thespinejournalonline.com/article/S152... ) shows increased spinal cord blood flow in-vivo via β-adrenergic receptor–mediated vasodilation, as spinal arteries lack α1-adrenergic receptors. 084
Reposted by Rebecca Hendrickson MD, PhDDaniel P. Moriarity @dpmoriarity.bsky.social · 04/01/2025"A study of federally funded research projects in the United States estimated that principal investigators spend on average about 45% of their time on administrative activities related to applying for and managing projects rather than conducting active research" www.pnas.org/doi/10.1073/... 33996462
Reposted by Rebecca Hendrickson MD, PhDCarolina Rezaval @crezaval.bsky.social · 15/11/2024Sex or survival—what’s more important? Excited to share our @Nature paper on how flies resolve this conflict. We found a dopamine-based filter that reduces threat perception, helping flies focus on courtship when close to mating. www.nature.com/articles/s41...nature.comMating proximity blinds threat perception - NatureA state-dependent dopamine filter system in the male Drosophila brain balances threat perception against the drive to mate. 03012
Reposted by Rebecca Hendrickson MD, PhDNora Verlaine @noraverlaine.bsky.social · 24/12/2024“Women are asked more questions during a seminar and the questions asked of women presenters are more likely to be patronizing or hostile. These effects are not due to women presenting in different fields, different seminar series, or different topics…” www.nber.org/papers/w28494nber.orgGender and the Dynamics of Economics SeminarsFounded in 1920, the NBER is a private, non-profit, non-partisan organization dedicated to conducting economic research and to disseminating research findings among academics, public policy makers, an... 26744302
Rebecca Hendrickson MD, PhD @hendricksonmd.bsky.social · 20/12/2024I feel like it's the first year it's been done this way, so makes sense if it was a bit inconsistent I guess. 020
Rebecca Hendrickson MD, PhD @hendricksonmd.bsky.social · 20/12/2024This year the tickets were actually needed if you wanted a non-alcoholic drink also (as some of us discovered after giving our away!). I did appreciate that they had a featured mocktail, though. It feels like it's less alcohol focused each year. I appreciate the progress. 120