iiinova — where your digital self keeps evolving

Reposted by Bratislav Dačević

Suzanne C. Jansen @suzannejansen.bsky.social · 19/09/2026

Excited to share our latest preprint! Oftentimes, interesting stories start as a puzzling observation in the lab, and that was definitely the case here. We combined kinetic analysis, mass spectrometry, and computational modeling to solve this mystery! Grateful for the collaboration!

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Reposted by Bratislav Dačević

Roelfes Group @roelfesgroup.bsky.social · 16/07/2026

Is was our absolute pleasure to help organise the @eurobic18.bsky.social together with Sylvestre Bonnet @unileiden.bsky.social. Special thanks to @wesleybrowne.bsky.social and everyone from @stratinghinst.bsky.social @rug.nl who contributed to a very successful and stimulating week at #EuroBIC18!

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Bratislav Dačević @hemadzer.bsky.social · 16/07/2026

A fantastic week at @eurobic18.bsky.social in Groningen! It was a great pleasure to present my latest research and also to help behind the scenes as part of the conference support team. This was also a very good opportunity to reconnect with friends, collaborators, and colleagues.

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Bratislav Dačević @hemadzer.bsky.social · 06/07/2026

See you at #EuroBIC18 next week in Groningen! I’ll be presenting my latest research on Wednesday morning. Looking forward to a great week of bioinorganic chemistry and catching up with colleagues!

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Reposted by Bratislav Dačević

Marcel Swart @marcelswart.bsky.social · 06/07/2026

Next week: @eurobic18.bsky.social Groningen 🇳🇱, July 12-17 eurobic18.eu/page/plenary...

eurobic18.eu

EuroBIC 18

EuroBIC 18th Conference Website

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Reposted by Bratislav Dačević

Roelfes Group @roelfesgroup.bsky.social · 11/03/2026

⏰ Deadline approaching! The 15 March deadline for submitting abstracts for oral communications to EuroBIC18 is fast approaching! We are excited to announce an outstanding lineup of plenary and keynote speakers – check them out on our website: 🌐 eurobic18.eu

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Bratislav Dačević @hemadzer.bsky.social · 09/03/2026

Last week I had the pleasure of attending the Netherlands’ Catalysis and Chemistry Conference (NCCC), where I presented my research on photobiocatalytic atroposelective biaryl coupling. I’m excited to share that I was awarded the Royal Society of Chemistry @rsc.org EES Catalysis Best Talk Prize!

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Reposted by Bratislav Dačević

Roelfes Group @roelfesgroup.bsky.social · 12/12/2025

Season’s greetings from the Roelfes and Mayer groups! 🎉🎄 Warm wishes to our colleagues, collaborators, and friends across the community for a joyful holiday season and an inspiring New Year ahead. ✨🧪

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Reposted by Bratislav Dačević

Fabrizio Casilli @fabricas.bsky.social · 08/08/2025

📢📢 New paper out! AI and networks can be used to predict distal mutations in proteins, even in artificial enzymes! Check out the article here ----‐> doi.org/10.1016/j.ij... Thread 1/5 🧵

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Reposted by Bratislav Dačević

Clemens @mayerlab.bsky.social · 17/07/2025

With #PFAS and other organofluorides wreaking havoc, we set out to engineer natural defluorinases for man-made organofluorides. All credit goes to the amazing @suzannejansen.bsky.social, who has outdone herself in this project! (1/5) www.biorxiv.org/content/10.1...

biorxiv.org

Engineering fluoroacetate dehalogenase by growth-based selections to degrade non-natural organofluorides

The widespread use of organofluorides in modern society has inadvertently led to the bioaccumulation of harmful pollutants, most prominently per- and polyfluorinated alkyl substances (PFAS). In princi...

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Reposted by Bratislav Dačević

Roelfes Group @roelfesgroup.bsky.social · 27/06/2025

#RepArtZymes pre-conference in Basel also brought together some of our old and current group members. @zhizhou1619.bsky.social @reubenlg.bsky.social

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Reposted by Bratislav Dačević

Roelfes Group @roelfesgroup.bsky.social · 12/05/2025

📢📢📢 PhD Opportunity! Join our research group at RUG! We're seeking a motivated PhD student for a project on biocatalytic cascade processes combining natural and designer enzymes, supported by machine learning. Click below to learn more — and feel free to share! sites.google.com/rug.nl/roelf...

sites.google.com

Roelfes group - Open Positions

PhD position on Hybrid biocatalytic cascades aided by Machine learning (1.0 FTE)

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Bratislav Dačević @hemadzer.bsky.social · 22/03/2025

Had an amazing week at the MetRaZymes @metrazymes.bsky.social Winter School in Hirschegg, Austria! It was a pleasure to learn, share, and connect with fellow researchers in our doctoral network. We organized and attended insightful lectures and workshops on ⬇️🧵

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Reposted by Bratislav Dačević

Roelfes Group @roelfesgroup.bsky.social · 14/02/2025

Our latest publication is out in @angewandtechemie.bsky.social! We generated and engineered a novel artificial metalloenzyme for the enantioselective synthesis of a panel of γ-nitro-carbonyl compounds on a preparative scale.

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Reposted by Bratislav Dačević

Bart Brouwer @brouwerb.bsky.social · 11/02/2025

Check out our latest preprint, in which we demonstrate the first example of using noncanonical 3-aminotyrosine (aY) as a catalytic residue for iminium activation in a designer enzyme! Thread ⬇️

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Reposted by Bratislav Dačević

Roelfes Group @roelfesgroup.bsky.social · 23/12/2024

Season's greetings from Roelfes and Mayer groups! Wishing our colleagues, collaborators, and the entire community a joyful holiday season and a prosperous New Year ahead! 🎉🎄✨🧪

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Reposted by Bratislav Dačević

Waser Group @lcsolab.bsky.social · 08/12/2024

OrgChem Starter pack has reached the 150 limit, so we started the sequel OrgChem2 go.bsky.app/GwH8tnF

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Waser Group @lcsolab.bsky.social · 05/12/2024

Our OrgChem Starter Pack is growing with already 122 entries, but we will start a volume 2 if we go over the 150 limit! go.bsky.app/NSEFPFJ

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Reposted by Bratislav Dačević

Roelfes Group @roelfesgroup.bsky.social · 06/12/2024

We are thrilled to share our new noble-metal enzyme design approach. We used the in-vivo incorporation of a noble-metal-binding ligand for ArM design to bridge the versatility of noble metals with the catalytic power of enzymes. Thread ⬇️

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Reposted by Bratislav Dačević

Roelfes Group @roelfesgroup.bsky.social · 05/12/2024

We are delighted to introduce our new Boron Designer Enzyme for the kinetic resolution of α-hydroxythioesters. For this activity, the noncanonical amino acid and a natural lysine residue have to work together to form a Hybrid Catalytic Dyad!

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