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Helena Reyes Gopar

@hamarillo.bsky.social
267 followers 332 following 33 posts

Researching human endogenous retroviruses using sc sequencing data 🏊🏼‍♀️ 👩🏻‍💻 🇲🇽 LCG UNAM alumna 🧬

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Reposted by Helena Reyes Gopar
Chuliang Song @clsong.com · 10/09/2026
A wonderful review by Stefano on 100 years of Lotka–Volterra models. Don’t miss the incredibly detailed Supplement, truly the “War and Peace” of LV models. I really wish it had existed when I was a grad student! doi.org/10.1146/annu...
doi.org
One Hundred Years of Lotka–Volterra Models
Over the past century, the generalized Lotka–Volterra (GLV) model has grown from a mathematical curiosity to a cornerstone of theoretical ecology. Here we celebrate the enduring legacy of Lotka and Vo...
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Reposted by Helena Reyes Gopar
Cell Press @cellpress.bsky.social · 26/08/2026
Beauty bias in butterfly research & conservation. Learn more in Current Biology: www.cell.com/current-biol... Leonardo Dapporto & colleagues
first page of paper: "Beauty bias in butterfly research & conservation."
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Reposted by Helena Reyes Gopar
Nature @nature.com · 26/08/2026
Dolly Parton was an advocate for vaccines, public health, literacy and marginalized communities go.nature.com/4wQ2DH8
go.nature.com
Dolly Parton dies aged 80 – researchers celebrate her contributions to science
The country singer was an advocate for vaccines, public health, literacy and marginalized communities.
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Reposted by Helena Reyes Gopar
FlyBase @flybase.bsky.social · 20/08/2026
Treat biological databases as infrastructure, not projects www.nature.com/articles/d41...
nature.com
Treat biological databases as infrastructure, not projects
Letter to the Editor
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Reposted by Helena Reyes Gopar
Ryan Stauffer @ryanswx.bsky.social · 17/07/2026
Every single regulatory grade monitor in the Chicago area is recording over 400 µg/m³ of PM2.5 smoke pollution. This is so far beyond anything in the historical record it’s difficult to communicate how extreme this event really is
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Reposted by Helena Reyes Gopar
Harmit Singh Malik @harmitmalik.bsky.social · 05/07/2026
"I first heard the term open science in the early 2000s, but it was really something many of us were doing well before that. When you work on methods, they're only really successful if someone else uses them” ---Steven Henikoff
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Helena Reyes Gopar @hamarillo.bsky.social · 24/06/2026
I used a spaghetti and glue to represent this for a high school assignment once. Truly iconic.
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Helena Reyes Gopar @hamarillo.bsky.social · 23/06/2026
🥲🥲🤣🥲🥲⚰️
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Reposted by Helena Reyes Gopar
Calle Börstell @cborstell.bsky.social · 04/06/2026
The quote "Actually, Frankenstein is the doctor, the monster is Frankenstein's Monster" but crossed out and replaced with "Actually, ggplot is the function, the package is ggplot 2"
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Reposted by Helena Reyes Gopar
Rita Strack @ritastrack.bsky.social · 23/05/2026
The MOSAIC paper is out in Nature Methods. For the record I went after this paper for *years* and was so happy when they sent it to me/us. www.nature.com/articles/s41...
nature.com
A multimodal adaptive optical microscope for in vivo imaging from molecules to organisms - Nature Methods
MOSAIC is a versatile multimodal microscope that allows seamless transition between various light-sheet, two-photon, label-free and super-resolution modalities. It is demonstrated in various systems r...
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Reposted by Helena Reyes Gopar
Ashkaan K. Fahimipour @akfbio.bsky.social · 22/05/2026
Reptiles with longer Wikipedia pages tend to be bigger. The relationship is a power law with exponent = 0.85. I guess humans really like writing about big lizards? The longest article is the Komodo Dragon.
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Reposted by Helena Reyes Gopar
Elphege Nora Lab at UCSF @elphegenoralab.bsky.social · 13/05/2026
Why can't we explain enhancer action despite 2 decades of chromosome conformation technologies? 😬 Our new study spearheaded by Leonid Mirny's group points to a flaw in our assumptions, and to a solution from physical principles By @timothyfoldes.bsky.social 💻& @karissalhansen.bsky.social 🧪 🧵👇
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Reposted by Helena Reyes Gopar
Randy Tan @oneseedfruit.bsky.social · 04/05/2026
The old internet still exists y'all neocities.org
neocities.org
Neocities
Create and surf awesome websites for free.
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Reposted by Helena Reyes Gopar
maybe: annie rauwerda @annierau.bsky.social · 04/05/2026
before the internet was a corporate hellscape it was built by ordinary people! the slop was wacky and homemade just like mom (and David) used to make. alas the good old days are over but I can't believe how lucky we are to have @archive.org to remember them :') web.archive.org/web/20080803...
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Reposted by Helena Reyes Gopar
MC Gambetta @mcgambetta.bsky.social · 04/05/2026
Hello all, our lab is recruiting a PhD candidate to study how 3D genome folding impacts gene regulation in development. We're located at the Center for Integrative Genomics department of the University of Lausanne, Switzerland. Please email me if interested. #PhDPosition, #PhDOpportunity
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Reposted by Helena Reyes Gopar
Mattan S. Ben-Shachar @mattansb.msbstats.info · 01/03/2026
This is great. I've given an example in class showing how priors can make some unidentified problems identifiable: a+b=6, solve for b. Prior: a=0~4
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Helena Reyes Gopar @hamarillo.bsky.social · 23/11/2025
Had a few days home in México, had a beautiful view as I left #Teotihuacan
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Reposted by Helena Reyes Gopar
Brian Merchant @bcmerchant.bsky.social · 27/10/2025
There's been endless talk about an AI bubble, but less about exactly how, why, and how much it's a bubble. So I turned to the framework put forward by scholars Brent Goldfarb and David A. Kirsch, authors of "Bubbles and Crashes," for assessing tech bubbles. Spoiler: On a scale of 1 to 8, AI is an 8
wired.com
AI Is the Bubble to Burst Them All
I talked to the scholars who literally wrote the book on tech bubbles—and applied their test.
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Helena Reyes Gopar @hamarillo.bsky.social · 20/10/2025
Why aren’t language models acting/interacting like a graph? (Or are they? Idk). It seems so obvious that while human conversations are iterative, they’re nonlinear and that’s how you get to the point/good stuff
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Reposted by Helena Reyes Gopar
Andy Fraser @andyfraser.bsky.social · 17/08/2025
The strongest argument I keep hearing for AI is that it makes many admin tasks and paperwork easy. This basically rephrases what many have been saying for decades - there is a vast and unnecessary administrative bloat mandated by “business best practice” that needs to vanish.
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Reposted by Helena Reyes Gopar
Julia M. Rohrer @dingdingpeng.the100.ci · 08/08/2025
Yesterday I attended Harin’s excellent defense where he talked about this study, which is a great reason to give it another shoutout. Does population size affect the diversity of the music that people listen to? Really nice example how to make use of a DAG in practice!
On the left, two DAGs showing associations between population size (the exposure) and between- (BID) or within- (WID) individual diversity and various third variables. On the right the estimated associations/effects. Without adjustment, diversity very strongly increases with population size. With adjustment, some of the increase disappears; in particular when moving from medium to large population sizes.
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Helena Reyes Gopar @hamarillo.bsky.social · 06/08/2025
Are housekeeping genes now the ones we see expressed in every single single-cell cell?
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Reposted by Helena Reyes Gopar
Ilya Boyandin @ilyabo.bsky.social · 31/07/2025
We just launched Foursquare Spatial Desktop – a geospatial analysis tool powered by embedded DuckDB and built on sqlrooms.org. Everything runs locally: your data stays on your machine, no cloud needed. A modern reimagining of Kepler.gl. Mac only for now. More coming. foursquare.com/products/spa...
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Reposted by Helena Reyes Gopar
Cell Reports Methods @cp-cellrepmethods.bsky.social · 20/06/2025
A single-cell transposable element atlas of human cell identity
dlvr.it
A single-cell transposable element atlas of human cell identity
Reyes-Gopar et al. introduce Stellarscope, a computational approach for quantifying locus-specific transposable element expression in single-cell RNA sequencing data. The authors profile human PBMCs and reveal transposable elements marking specific cell subtypes. Stellarscope is available as an open-source package and promises to enable continued study of “genomic dark matter.”
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Helena Reyes Gopar @hamarillo.bsky.social · 22/07/2025
Thrilled to share this work! I am honored to learn from @mlbendall.bsky.social and so grateful for his guidance and mentorship. Stellarscope is just the beginning! There is so much to learn about TEs and now we can all explore the uncharted territory of single cell retro-genomics 🧬🔭
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Reposted by Helena Reyes Gopar
skelly @iid.bsky.social · 20/07/2025
do you ever stare at the ceiling and think about how the worldwide scientific establishment did the impossible and created a COVID vaccine in under a year and the response of the general public has been to go on an unstoppable rampage to destroy science and scientists
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Reposted by Helena Reyes Gopar
Mireya Plass @mireyaplass.bsky.social · 14/07/2025
I’m really happy to present #SCALPEL, a new #Nextflow tool to quantify transcript isoforms at the single-cell level using conventional 3’ scRNA-seq data #scRNA-seq #single-cell #tools #isoforms www.nature.com/articles/s41...
nature.com
Quantification of transcript isoforms at the single-cell level using SCALPEL - Nature Communications
Single-cell RNA-seq facilitates the study of transcriptome diversity in individual cells. Here, authors introduce a tool for isoform quantification at the single-cell level using 3’ scRNA-seq data, co...
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Reposted by Helena Reyes Gopar
Saloni @scientificdiscovery.dev · 19/07/2025
Sad news: The dataset behind this famous chart on the decline in costs of genome sequencing has had its NIH funding cut. I loved this chart because it was the first that made me appreciate the impact of dataviz. But it also tracked progress towards an ambitious goal ($1000 genome) that succeeded.
NHGRI (at NIH)'s chart on the declining cost of sequencing a human genome from 2001 to 2021, falling faster than Moore's law. The "$1,000 genome" catchphrase was first publicly recorded in December 2001 at a scientific retreat to discuss the future of biomedical research following publication of the first draft of the Human Genome Project (HGP), convened by the National Human Genome Research Institute at Airlie House in Virginia.[5] The phrase neatly highlighted the chasm between the actual cost of the Human Genome Project, estimated at $2.7 billion over a decade, and the benchmark for routine, affordable personal genome sequencing.

On 2 October 2002, Craig Venter introduced the opening session of GSAC (The Genome Sequencing and Analysis Conference) at the Hynes Convention Center in Boston: "The Future of Sequencing: Advancing Towards the $1,000 Genome." Speakers included George M. Church and executives from 454 Life Sciences, Solexa, U.S. Genomics, VisiGen and Amersham plc.[6][7] In 2003, Venter announced that his foundation would earmark $500,000 for a breakthrough leading to the $1,000 genome.[8] That sum was subsequently rolled into the Archon X Prize.

In October 2004, NHGRI introduced the first in a series of '$1,000 Genome' grants designed to advance "the development of breakthrough technologies that will enable a human-sized genome to be sequenced for $1,000 or less."[9]
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Reposted by Helena Reyes Gopar
Alejandra Medina-Rivera @alemedinarivera.bsky.social · 02/07/2025
Thanks @lecteroide.bsky.social for the opportunity to share the efforts developed in MexOmics www.the-scientist.com/mexomics-map...
the-scientist.com
MexOMICs Maps the Genetic and Social Landscape of Disease in Mexico
By focusing on twins and patients with lupus and Parkinson’s disease, a Mexican consortium is generating critical data to understand health and disease in the country.
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Helena Reyes Gopar @hamarillo.bsky.social · 28/06/2025
One old fish needed to sense its environment and now I have to floss every night (Isn’t evolution the coolest thing ever?! 👹🌀🧬🤗)
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Helena Reyes Gopar @hamarillo.bsky.social · 27/06/2025
I wonder if easy-to-remember memories that are accompanied by ‘negative’ strong emotion (i.e. the opposite of insight?) follow the same or a different pathway in the brain activity
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Reposted by Helena Reyes Gopar
Jess Rose @jesslynnrose.bsky.social · 25/06/2025
Been horrifying teammates by referring to undocumented information that's held only in people's heads as "locked in meat storage". Please use this with your teams/projects and report back on how they like it?
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Reposted by Helena Reyes Gopar
Daniela Robles-Espinoza @daniela-oaks.bsky.social · 17/06/2025
@dartar.bsky.social: Why Latin America? @chanzuckerberg.bsky.social #CZIAcceleratingScienceLA
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Helena Reyes Gopar @hamarillo.bsky.social · 07/06/2025
My train does epigenetics and I love it #LIRR
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Reposted by Helena Reyes Gopar
matthew.bendall @mlbendall.bsky.social · 20/05/2025
🚨 Excited to share our latest work: 🚨 @bhavyasighs.bsky.social et al. show that locus-specific #HERV expression can reveal the origins and heterogeneity of B-cell lymphomas! Locus-specific human endogenous retroviruses reveal lymphoma subtypes www.cell.com/iscience/ful... #TEsky #TEworldwide 1/
cell.com
Locus-specific human endogenous retroviruses reveal lymphoma subtypes
Genomics; Virology
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Helena Reyes Gopar @hamarillo.bsky.social · 07/12/2024
My first #bluesky "flutter" I guess 🦋🌪️ o o o o o o o o o o o \ o o o o / o o o o / o o o o \ o o o o o o o o o o o
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