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Carla Golden

@goldenneurons.bsky.social
264 followers 307 following 34 posts

NIDA K99 postdoc at NYU and former Simons Society Junior Fellow. Studying how estrogen modulates dopamine and learning in rats in the Constantinople lab. She/her.

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Carla Golden @goldenneurons.bsky.social · 28/08/2026
Amazing work!! Congratulations!
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Dr. Garrett Blair @garrettblair.bsky.social · 13/08/2026
Postdocs! Apply by this Friday (8/15) for NYU Neuroscience's Seminars by Postdocs in Neuroscience: Extramural Series, SPiNES --> med.nyu.edu/departments-... It's a great opportunity to share your work!
A flyer for the 2026 Seminars by Postdocs in Neuroscience: Extramural Series (SPiNES) hosted by the NYU Neuroscience Institute
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Constantinople lab @constantinoplelab.bsky.social · 03/04/2026
Excited to share our recent review, which highlights algorithmic and implementational degeneracy in studies of cognition: www.sciencedirect.com/science/arti...
sciencedirect.com
Addressing degeneracy in rodent studies of cognition
In order to relate neural dynamics to cognitive computations, it is critical to determine whether subjects are employing behavioral strategies that ac…
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Constantinople lab @constantinoplelab.bsky.social · 25/03/2026
Thrilled to share our new paper, which shows that the relative timing of cholinergic and dopamine release dynamically gates whether dopamine acts as an RPE for in vivo plasticity and reinforcement learning. www.nature.com/articles/s41...
nature.com
Acetylcholine demixes heterogeneous dopamine signals for learning and moving
Nature Neuroscience - Jang et al. measured dopamine and acetylcholine release in the striatum of rats performing a decision-making task and found that the relative timing of cholinergic and...
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Carla Golden @goldenneurons.bsky.social · 20/03/2026
Thank you!
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Carla Golden @goldenneurons.bsky.social · 20/03/2026
Thanks, Orna!
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Carla Golden @goldenneurons.bsky.social · 20/03/2026
Thanks, Ben! 😊
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Carla Golden @goldenneurons.bsky.social · 20/03/2026
Thank you, Megan!!
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Carla Golden @goldenneurons.bsky.social · 20/03/2026
Thanks, Kurt!!
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Carla Golden @goldenneurons.bsky.social · 20/03/2026
Thank you, Kirstie!!
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Carla Golden @goldenneurons.bsky.social · 20/03/2026
Thank you, Mark!! 💕 I’m over the moon.
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Carla Golden @goldenneurons.bsky.social · 20/03/2026
Thank you to my brilliant mentor, @constantinoplelab.bsky.social, my mentors from graduate school, @jdbux.bsky.social, @markgbaxter.bsky.social, and Hala Harony-Nicolas, and my comentor on the proposal, Eric Klann.
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Carla Golden @goldenneurons.bsky.social · 20/03/2026
Grateful to receive a ✨K99/R00✨ after much uncertainty! Still worried about scientific funding and the future of our work. Excited to reveal how estrogen modulates neuromodulator and neural dynamics, de novo protein synthesis, and temporal discounting with a novel task the rats are already crushing.
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Chris Zimmerman @czimmerman.bsky.social · 13/03/2026
📢📢 My lab at @utah.edu is officially open and I'm RECRUITING — especially techs/specialists and postdocs! Our research focuses on the neurobiology of interoception and learning & memory using tools from systems/comp neuro. Please share! 🧠🏔️🏜️ Apply/more info: zimmerman-lab.org#positions
University of Utah Health Campus at sunset. Image courtesy of the University of Utah.
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500 Women Scientists @500womensci.bsky.social · 03/02/2026
all these emails between academics and Epstein are more testimony of what women in academia have to contend with 😡
email exchange between Epstein and Duke professor Dan Ariely discussing a meet up and Ariely asking about a redhead that was with Epstein
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Constantinople lab @constantinoplelab.bsky.social · 30/01/2026
Our lab will be boycotting biotech vendors that have contracts with ICE (e.g., Fisher, Agilent), and telling them why. If you google “vendorname usa spending”, you can see purchases for specific depts including ICE on usaspending.gov. Please talk to your labs and email your vendors!
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Arif A. Hamid, Ph.D. @arifahamid.bsky.social · 30/12/2025
Excited to share latest study from the lab by an amazing RA, Dylan Flink. We solved a small (important) puzzle while in the trenches of a larger (wavy 🌊) puzzle. www.biorxiv.org/content/10.6... 🧵...
biorxiv.org
Dual cholinergic mechanisms for sculpting striatal dopamine in vivo
Striatal dopamine (DA) and acetylcholine constitute a computationally powerful neuromodulatory dyad that orchestrates action selection, motivational vigor, and reward learning. Striatal cholinergic in...
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Carla Golden @goldenneurons.bsky.social · 23/12/2025
Yay congrats!!
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Carla Golden @goldenneurons.bsky.social · 16/12/2025
🤯
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Grace Lindsay @neurograce.bsky.social · 08/12/2025
Spread the word: I'm looking to hire a postdoc to explore the concept of attention (as studied in psych/neuro, not the transformer mechanism) in large Vision-Language Models. More details here: lindsay-lab.github.io/2025/12/08/p... #MLSky #neurojobs #compneuro
lindsay-lab.github.io
Lindsay Lab - Postdoc Position
Artificial neural networks applied to psychology, neuroscience, and climate change
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Carla Golden @goldenneurons.bsky.social · 27/11/2025
Congratulations, Margaret and Ben!!
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Carla Golden @goldenneurons.bsky.social · 26/11/2025
Thank you for the great summary, @thetransmitter.bsky.social, and the shout-outs from scientists we admire. There is so much we don’t know about how sex hormones modulate behavior and we’ll keep exploring!
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Paul Masset @paulmasset.bsky.social · 19/11/2025
I am recruiting graduate students for the experimental side of my lab @mcgill.ca for admission in Fall 2026! Get in touch if you're interested in how brain circuits implement distributed computation, including dopamine-based distributed RL and probabilistic representations.
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Nicolas Tritsch @nictritsch.bsky.social · 21/11/2025
As the Neuroscience 2025 meeting comes to a close, it's time for us to think about the future. Do you want to help us shape neuroscience research and future @sfn.org meetings? Consider nominating yourself or colleagues: www.sfn.org/about/volunt...
sfn.org
Call for Nominations
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Carla Golden @goldenneurons.bsky.social · 20/11/2025
Thank you, Mel!!
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Carla Golden @goldenneurons.bsky.social · 20/11/2025
We LOVED this commentary! I might borrow that football 🏈 example in future talks…
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Nicola Sambuco @nicolasambuco.bsky.social · 19/11/2025
1/3 New Nature Neuroscience paper on estrogen & dopamine RPEs. Female rats in high-estradiol phase (proestrus) show stronger trial-by-trial adjustment of response vigor in a RL task: they start the next trial faster after better rewards. www.nature.com/articles/s41... #RewardSignals #neuroskyence
nature.com
Estrogen modulates reward prediction errors and reinforcement learning - Nature Neuroscience
Dopamine encoding of reward prediction errors naturally fluctuates over females’ reproductive cycles with estrogenic signaling due to reduced expression of dopamine reuptake proteins.
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Constantinople lab @constantinoplelab.bsky.social · 17/11/2025
Who wore it better? Our new paper shows that rat OFC supports Bayesian inference of hidden states! With neural correlates of inferred state transitions at the level of single neurons and population-level latent factors. www.sciencedirect.com/science/arti...
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Carla Golden @goldenneurons.bsky.social · 12/11/2025
Preach. I am finding The Best Model Fit and the perfect has become the enemy of the good.
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Constantinople lab @constantinoplelab.bsky.social · 12/11/2025
Check out our posters at #SfN25 this Saturday! @aqperkins.bsky.social @adiraj95.bsky.social @goldenneurons.bsky.social
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Carla Golden @goldenneurons.bsky.social · 12/11/2025
Thank you, Arif!!
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Carla Golden @goldenneurons.bsky.social · 11/11/2025
Thanks, Kavya!!
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Carla Golden @goldenneurons.bsky.social · 11/11/2025
Thank you, Orna!
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Carla Golden @goldenneurons.bsky.social · 11/11/2025
Thanks, Kurt!! ☺️
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Carla Golden @goldenneurons.bsky.social · 11/11/2025
Such a great question! I’d love to know the answer to that.
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Carla Golden @goldenneurons.bsky.social · 11/11/2025
Thank you, Mark!!
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Carla Golden @goldenneurons.bsky.social · 11/11/2025
Thanks, Ben!!
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Carla Golden @goldenneurons.bsky.social · 11/11/2025
Many thanks to our coauthors, the undergraduate students and technicians who contributed to this work, and support from the NIH and @simonsfoundation.org. #blueprint 7/7
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Carla Golden @goldenneurons.bsky.social · 11/11/2025
Altogether, this suggests that estradiol, by way of its receptors in the ventral tegmental area, modulates learning! #blueprint 6/7
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Carla Golden @goldenneurons.bsky.social · 11/11/2025
Lastly, knocking down expression of estrogen receptors in the ventral tegmental area, where dopamine transporter expression could be regulated by estradiol, suppressed learning. #blueprint 5/7
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Carla Golden @goldenneurons.bsky.social · 11/11/2025
Next, mass spectrometry revealed that dopamine transporters in the nucleus accumbens core are reduced around the time estradiol peaks, allowing for greater phasic dopamine encoding of reward prediction errors. #blueprint 4/7
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Carla Golden @goldenneurons.bsky.social · 11/11/2025
First, we found that with more estradiol, trial initiation times are more sensitive to changing reward rates. We then found that this enhanced learning about reward rate could be explained by stronger reward prediction errors in the nucleus accumbens core. #blueprint 3/7
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Carla Golden @goldenneurons.bsky.social · 11/11/2025
Take a journey with us from serum estradiol to its relationship to striatal protein expression to how that modulates dopamine dynamics, which in turn enhances learning about reward rates – all tied together with a descriptive computational model! #blueprint 2/7
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Carla Golden @goldenneurons.bsky.social · 11/11/2025
Thrilled to share our new paper, out now in @natneuro.nature.com, uncovering how estradiol, the most potent estrogen, modulates reinforcement learning and reward prediction errors across biological levels. www.nature.com/articles/s41... #blueprint 1/7
nature.com
Estrogen modulates reward prediction errors and reinforcement learning - Nature Neuroscience
Dopamine encoding of reward prediction errors naturally fluctuates over females’ reproductive cycles with estrogenic signaling due to reduced expression of dopamine reuptake proteins.
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Constantinople lab @constantinoplelab.bsky.social · 19/06/2025
Rat-mon y Cajal, our lab mascot, is a pro at our task because he went to kindergarten first. His nemesis, Le Chat GPT, just copied off everyone else’s homework. www.nature.com/articles/s42...
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Shane Liddelow @liddelowsa.bsky.social · 15/06/2025
Calling all Neuroscience postdocs! 🧠 Share your research through SPiNES (Seminars from Postdocs in Neuroscience: Extramural Series) from the NYUGSoM Department of Neuroscience. Applications close 08/20/25. Apply today! 👉 nyumc.qualtrics.com/jfe/form/SV_... #Neuroscience #Postdoc #ResearchOpportunity
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Carla Golden @goldenneurons.bsky.social · 28/05/2025
I mean, we have a city rat czar. What other animal deserves this much attention.
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Constantinople lab @constantinoplelab.bsky.social · 22/05/2025
During Q&A, whenever someone asks a question about our "mice."
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Tracy Bale @thebalelab.bsky.social · 01/04/2025
THIS is outrageous and scary! RFK making his own journal that appears to be associated with a medical society.There is no such thing as the Academy of Public Health! They can use this to make false claims in medicine and science, including for vaccines. These are not peer reviewed nor scientific!
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Nick Audette (He/His) @njaudette.bsky.social · 07/03/2025
Join our brand-new lab at UConn studying flexible sensory processing in mice! We're hiring a full-time lab tech - a great fit for recent grads looking to get experience with systems and behavioral neuroscience research. Apply here: jobs.hr.uconn.edu/cw/en-us/job...
jobs.hr.uconn.edu
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