gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 04/09/2026Someone appears to have got lost lol 000
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 04/09/2026The same applies in another case, where the draft cites a relevant Kim et al, 2019 – but the published paper has an irrelevant reference (but also Kim et al, 2019) in its place. 000
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 04/09/2026I wonder if this particular error is BMC's fault – as part of the peer review reports, there is a resubmitted draft that adds this section and correctly cites a meta-analysis of 67 RCTs (also Huang et al., 2026). static-content.springer.com/openpeerrevi... www.nature.com/articles/s41... 100
Reposted by @gladstonebrookes.bsky.socialGeorgia Tomova @georgiatomova.bsky.social · 12/08/2026How many nutrition meta-analyses pool estimates for incomparable research questions, due to different energy adjustment strategies? We looked at an illustrative sample. The answer was all of them! Delighted to share our new meta-scientific review, led by @nataliaortega.bsky.social 👇academic.oup.comMeta-analyses of dietary exposures must consider energy adjustment: recommendations from a meta-scientific reviewAbstract. In observational studies of dietary exposures, the energy adjustment strategy directly alters the effect being estimated. Adjusting for total ene 24714
Reposted by @gladstonebrookes.bsky.socialMatthew Nagra, ND @drmatthewnagra.bsky.social · 28/04/2026🚨NEW PUBLICATION!🚨 We reviewed virtually every major claim behind the seed oil hysteria, and the evidence doesn’t support the fear. The controversy is largely social media-driven, built on ecological correlations, mechanistic speculation, and flawed trials...tandfonline.comConcerns about the health effects of industrially produced seed oils are without scientific foundation: a scoping narrative review of the clinical and observational evidenceTo reduce cardiovascular disease (CVD) risk, worldwide dietary guidelines emphasize limiting saturated fatty acid (SFA) intake, and replacing SFAs with unsaturated fatty acids, especially polyunsat... 1104
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 21/04/2026This doesn't seem surprising when you observe that the y-axis variable is funding *per death* – we'd expect this variable to be inversely associated with mortality, because mortality is right there in the denominator. 020
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 06/03/2026So we're in agreement that it is *not* the case that almost all respondents were from India? 110
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 05/03/2026I interpreted it as '23,268 adults, where adult is the given age range in the given countries.' I don't think it makes sense otherwise. 100
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 05/03/2026India was only one country of 29, contributing a bit under 10% of the total sample. www.kcl.ac.uk/news/almost-... 100
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 26/02/20261. www.nature.com/articles/s41... 2. www.nature.com/articles/s41...nature.comUnveiling the correlation between dietary fiber intake and endometriosis: a cross-sectional analysis of NHANES data - Scientific ReportsScientific Reports - Unveiling the correlation between dietary fiber intake and endometriosis: a cross-sectional analysis of NHANES data 010
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 26/02/2026Fun finding: two studies on ostensibly the same research question using the same dataset published in the same journal a few months apart that find the opposite results (Fibre being associated with higher odds of endometriosis in one and lower odds in the other) 110
Reposted by @gladstonebrookes.bsky.socialMark A. Hanson @hansonmark.bsky.social · 13/01/2026We've got ISSUES. Literally. We scraped >100k special issues & over 1 million articles to bring you a PISS-poor paper. We quantify just how many excess papers are published by guest editors abusing special issues to boost their CVs. How bad is it & what can we do? arxiv.org/abs/2601.07563 A 🧵 1/n 17514314
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 13/01/2026Though I think there is actually a small issue with this meta-analysis that no one has noticed (but I doubt it would meaningfully change the conclusions). 000
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 13/01/20262. As it was only on patients following laparoscopic surgery, this limits generalisability to other groups of endometriosis patients (which is true, but that's just what their research question was and it's clear throughout, so I don't see an issue with the actual methodology). 110
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 13/01/2026Lol yeah. In fairness, I don't think the letter you linked is really interesting/damning to that meta-analysis. Their points are: 1 . There was high heterogeneity, so they think the authors should have done a meta-regression and subgroup analyses (but this isn't feasible with so few studies). 210
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 13/01/2026Ah, I see, thank you. That's a different thing in a similarly-named but separate journal (Journal of Minimally Invasive Gynecology vs. Gynecology and Minimally Invasive Therapy). 100
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 13/01/2026Not to my knowledge... Where are you seeing this? As far as I know, the journal hasn't published any letter or response. 100
Reposted by @gladstonebrookes.bsky.socialKevin C Klatt, PhD, RD @kcklatt.bsky.social · 08/01/2026For anyone interested in the new Dietary Guidelines, here's a breakdown and my thoughts: kcklatt.substack.com/p/ambiguous-...kcklatt.substack.comAmbiguous DGAs & The Rancher's PyramidTame on the surface, more underneath 22211
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 08/01/2026What would say is the best evidence the following the recs in these guidelines increases risk of pancreatitis? 010
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 04/01/2026I haven't got around to listening to this yet but now I definitely need to! 100
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 04/01/2026Congrats on the new paper @nataliaortega.bsky.social @pwgtennant.bsky.social @georgiatomova.bsky.social @deirdretobias.bsky.social @christinadahm.bsky.social (I hope this is a faithful summary 😬) 120
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 04/01/2026E.g. instead of "the association between red meat and CHD was ...", one might use "the substitution of 50 g/day of fish in place of 50 g/day of red meat was associated with ... lower/higher risk of CHD." 100
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 04/01/2026...estimates that target the same research question, and clearly explaining what quantitative results are describing. 100
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 04/01/2026They provide recommendations for researchers conducting meta-analyses, such as clearly specifying in advance what causal effects you are interested in, identifying what adjustments will produce an estimate for this effect, only pooling... 100
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 04/01/2026This review found that most studies are implicitly estimating substitution effects, but this is rarely acknowledged or justified in the original studies or accounted for in meta-analyses. This means the meta-analyses are pooling data for a mix of different research questions, not a single one. 100
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 04/01/2026If one then combines estimates in a meta-analysis without considering whether total energy or other dietary components were adjusted for, you end up essentially pooling estimates for different effects (not good!) 100
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 04/01/2026Adjustment for other dietary components on top of total energy limits what the substitution can be (e.g. substitution of red meat for some combination of foods in the rest of the diet *excluding* fruits and vegetables). 100
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 04/01/2026...keeping the rest of the diet the same) to substitution (increasing intake of that food while decreasing some other component(s) of the diet). 100
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 04/01/2026Meta-analyses of dietary exposures must consider energy adjustment (preprint) 🧵 arxiv.org/abs/2512.07531 In observational studies, adjustment for energy intake changes the nature of the effect being estimated – from addition (increasing or decreasing intake of that food while... 122
Reposted by @gladstonebrookes.bsky.socialDarren Dahly @statsepi.bsky.social · 29/12/2025It has a name now 😜 Many thanks to Ken for agreeing to put his good name to my...artwork. The image is in the public domain (CC 0), but citations to the linked documents are warmly welcomed. ✅ zenodo.org/records/1808... ✅ pubmed.ncbi.nlm.nih.gov/24452418/ 1022875
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 18/12/2025This has been published and (supposedly) peer-reviewed. journals.lww.com/gmit/fulltex...journals.lww.com 100
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 16/12/2025@gidmk.bsky.social @elisabethbik.bsky.social @mumumouse2.bsky.social @academic-integrity.bsky.social @smutclyde.bsky.social @thatsregrettab1.bsky.social Sorry if the tagging is annoying, but you all are cool people I follow who are into research integrity, so thought you might find it interesting. 250
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 16/12/2025Interesting finding: A rather odd meta-analysis in which not a single study meets their inclusion criteria, and nearly 100% of the data presented is incorrect. I have genuinely no idea how the heck you could end up with this (AI hallucinations? Something else?) pubpeer.com/publications... 331
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 15/12/2025I hear diamond has similar properties. 010
Reposted by @gladstonebrookes.bsky.socialPeter Tennant @pwgtennant.bsky.social · 08/12/2025Thrilled to share my latest paper entitled, "Estimating Discrimination in Sentencing: Distinguishing between Good and Bad Controls" Led by @jpinasanchez.bsky.social, the paper introduces a framework for examining discrimination in criminal justice processes. 🧵 1/10 publicera.kb.se/ejels/articl... 27534
Reposted by @gladstonebrookes.bsky.socialDarren Dahly @statsepi.bsky.social · 13/11/2025We did a thing. 😬 1424257
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 04/11/2025Typo in one of the summary tables, I think. 360 out of 1000 is 36%, not 3.6%, so the absolute risk difference should be 3% (not 0.3%), which is clinically significant under their criteria (so not "little to no difference" as is currently written). 100
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 04/11/2025They seem to have decided that the minimal clinically important difference is 5% absolute risk difference for MACE and 1% for mortality, irrespective of follow-up time. Though I don't see an explanation for why these were chosen. 010
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 18/10/2025This was just retracted. onlinelibrary.wiley.com/doi/10.1002/... pubpeer.com/publications... 010
Reposted by @gladstonebrookes.bsky.socialHealth Nerd @gidmk.bsky.social · 22/09/2025Remember that cruciferous vegetables and cancer study I wrote about recently? Turns out it's even more borked than I said. Some excellent sleuthing here, the study probably needs to be retracted or extensively corrected. 0182
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 22/09/2025You're right, I agree the p-values part is actually fine, and I fully retract that part of my criticism. Sorry for the confusion. 020
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 21/09/2025This guy's takes on nutrition include the belief that seed oils cause school shootings by weakening your connection to God, and that heroin overdose is because of seed oils. 2101
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 21/09/2025...there is apparent cherry-picking that biases the result towards finding a beneficial effect of cruciferous vegetable consumption, and the sensitivity analysis is full of incorrect p-values. pubpeer.com/publications...pubpeer.comPubPeer - Cruciferous vegetables intake and risk of colon cancer: a do...There are comments on PubPeer for publication: Cruciferous vegetables intake and risk of colon cancer: a dose–response meta-analysis (2025) 140
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 21/09/2025Hey @gidmk.bsky.social, following this post, I dug into the study further, and it turns out there are a *lot* more issues with it. Only one of the estimates used is actually what they claim it is (odds ratio for the association between highest vs lowest intake of cruciferous veg and colon cancer).. 150
Reposted by @gladstonebrookes.bsky.socialSophie E. Hill @sophieehill.bsky.social · 05/09/2025My thread on the Neurology paper on sweeteners & cognitive health: skywriter.blue/pages/did:pl... And a follow-up thread on some weird patterns in the Appendix tables: skywriter.blue/pages/did:pl... Collated by Skywriter onto a web page for easier reading! 34711
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 01/09/2025So it could be a (butter)fly on the wall? 010
gladstonebrookes.bsky.social @gladstonebrookes.bsky.social · 29/08/2025Cruciferous vegetables and colon cancer. pmc.ncbi.nlm.nih.gov/articles/PMC...pmc.ncbi.nlm.nih.govCruciferous vegetables intake and risk of colon cancer: a dose–response meta-analysisColon cancer (CC) is the third most diagnosed malignancy and second leading cause of cancer mortality globally, with ~ 1.9 million new cases and 903,859 deaths annually (Bray et al. in CA Cancer J Cli... 000
