iiinova — where your digital self keeps evolving

Giulia De Rossi @giuliaderossi.bsky.social · 15/04/2026

Honoured to be among the recipients of the Academy of Medical Sciences Springboard Award!🎉 My lab will investigate how and why the tiny blood vessels at the back of the eye are lost with age. Thank you @acmedsci.bsky.social @ucl.ac.uk @ucleye.bsky.social - looking forward to starting!!

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Reposted by Giulia De Rossi

UCL Faculty of Brain Sciences @uclbrainscience.bsky.social · 17/11/2025

👩🔬 Meet Dr @giuliaderossi.bsky.social, Senior Research Fellow at @ucleye.bsky.social. She speaks to us about her career highlights and why it's such an exciting time to work in the field of Ophthalmology. 👉 www.ucl.ac.uk/brain-scienc...

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Reposted by Giulia De Rossi

Reinhold Medina @reinholdmedina.bsky.social · 01/09/2025

🚀 Join the frontier of discovery! We’re hiring a skilled technician to work with world-leading scientists on cell ageing, stem cells & eye health. Be part of research shaping the future of medicine. www.jobs.ac.uk/job/DOM762/t...

jobs.ac.uk

Technician – Grade 5 at University of Liverpool

Find your next professional services job in higher education on jobs.ac.uk. Apply now for the Technician – Grade 5 role and more.

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Reposted by Giulia De Rossi

Hao Yin @haoyin.bsky.social · 12/11/2025

#DiabeticRetinopathy EC LRG1 ⏫Pericyte TGFβ▶️ Hypercontractile & matrix phenotype Lrg1 KO in hyperglycemic🐭 rescues 👉Retinal vascular permeability 👉⬇️Density φ Oxygenation in deep vasc plexus 👉⬇️ERG b-wave amp @giuliaderossi.bsky.social #ScienceTM 2025 www.science.org/doi/10.1126/...

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Reposted by Giulia De Rossi

Science Magazine @science.org · 03/11/2025

The protein LRG1 acts as a critical player in the initial onset of diabetic retinopathy by disrupting TGF-beta signaling in pericytes and triggering pathological constriction of capillaries, according to new #ScienceTranslationalMedicine work in mice. scim.ag/3Jx6NRu

scim.ag

Leucine-rich α-2-glycoprotein 1 initiates the onset of diabetic retinopathy in mice

LRG1-driven microvascular dysfunction triggers early diabetic retinopathy, highlighting a potential therapeutic target.

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Reposted by Giulia De Rossi

Boca Scientific Inc. @bocascientificinc.bsky.social · 24/10/2025

A study from @ucleye.bsky.social has identified a key #protein that triggers diabetic retinopathy. The protein LRG1 is the cause of the early damage and targeting this could offer a way to protect vision. #Ophthalmology www.science.org/doi/10.1126/...

science.org

Leucine-rich α-2-glycoprotein 1 initiates the onset of diabetic retinopathy in mice

LRG1-driven microvascular dysfunction triggers early diabetic retinopathy, highlighting a potential therapeutic target.

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Reposted by Giulia De Rossi

Professor Steve Moss @stephenemoss.bsky.social · 25/10/2025

Time for my weekly post, and today I report on some exciting new research from my lab. Especially for any diabetics out there. Important News from the World of Diabetes open.substack.com/pub/stephene...

open.substack.com

Important News from the World of Diabetes

A breakthrough in understanding sight loss

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Reposted by Giulia De Rossi

Science X / Phys.org @sciencex.bsky.social · 23/10/2025

A key protein has been identified as an early trigger of diabetic retinopathy, offering a potential new approach to prevent vision loss in people with diabetes before significant damage occurs. doi.org/g97skc

medicalxpress.com

Early trigger of diabetic eye disease identified

A team led by UCL scientists has identified a key protein that triggers diabetic retinopathy—a condition caused by high blood sugar damaging the retina's blood vessels and a leading cause of sight loss among working-age adults.

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Reposted by Giulia De Rossi

UCL News @uclnews.bsky.social · 23/10/2025

A team led by Dr @giuliaderossi.bsky.social @ucleye.bsky.social has identified a key protein that triggers diabetic retinopathy – a leading cause of sight loss among working-age adults – in a finding that has the potential to revolutionise how the disease is treated

ucl.ac.uk

Early trigger of diabetic eye disease identified

A team led by UCL scientists has identified a key protein that triggers diabetic retinopathy – a condition caused by high blood sugar damaging the retina’s blood vessels and a leading cause of sight l...

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Giulia De Rossi @giuliaderossi.bsky.social · 23/10/2025

So amazing to see our work on the cover of Science Translational Medicine!!

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Reposted by Giulia De Rossi

Science Magazine @science.org · 22/10/2025

The new issue of #ScienceTranslationalMedicine is out now! Mass production of regulatory T cells treats autoimmune disorders in mice, a preclinical study uncovers a promising therapeutic target in diabetic retinopathy, and more. scim.ag/3WeFm1R

The cover shows a flattened view of the mouse retinal deep vascular plexus, highlighting the microvascular tree (white).

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Reposted by Giulia De Rossi

UCL Translational Research Office @ucltro.bsky.social · 23/10/2025

@ucl.ac.uk scientists discover early trigger of diabetic eye disease, paving the way for new sight-saving treatments. The TRO is proud to support research projects like this by working closely with our academics and see the impactful work progressing for patient benefits. Full story: bit.ly/3Lo0vEk

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Reposted by Giulia De Rossi

John Greenwood @greenwoodjohn.bsky.social · 22/10/2025

Leucine-rich α-2-glycoprotein 1 initiates the onset of diabetic retinopathy in mice | Science Translational Medicine www.science.org/doi/10.1126/... Our latest publication regarding LRG1. Congratulations to Dr De Rossi for her immense contribution. So proud to have made a significant contribution.

science.org

Leucine-rich α-2-glycoprotein 1 initiates the onset of diabetic retinopathy in mice

LRG1-driven microvascular dysfunction triggers early diabetic retinopathy, highlighting a potential therapeutic target.

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Giulia De Rossi @giuliaderossi.bsky.social · 23/10/2025

📢Our new paper is out in @science.org #ScienceTranslationalMedicine 📢 Diabetic retinopathy (DR) is a leading cause of blindness. Patients show vascular changes in their retinas long before vision starts to deteriorate. What triggers these early defects? Could targeting them prevent vision loss? 🧵

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Giulia De Rossi @giuliaderossi.bsky.social · 17/10/2025

And so it begins! 🎓 Emily’s PhD journey into shedding light on the fibrotic response in wet AMD. Huge thanks to @macularsociety.org for supporting this talented young scientist, and to @amandajcarr.bsky.social for co-supervising! 👏✨

Emily, a macular society funded phd student, working with cells

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Giulia De Rossi @giuliaderossi.bsky.social · 18/07/2025

What an absolute pleasure it’s been to host Precious in my lab these past few weeks! Honoured to play a small part in what I’m sure will be a stellar career. Huge thanks @diabetesuk.bsky.social and Windsor Fellowship for funding her internship.

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