Three-dimensional traction force microscopy (3DTFM) in fibrillar hydrogels typically models the extracellular matrix as a continuum. We present data-driven 3DTFM (DD-TFM), which reconstructs fiber net...

Septins are cytoskeletal proteins that contribute to essential cellular processes such as cell migration and cell division through interactions with the cell membrane and the cytoskeleton. High expres...

The cytoskeleton, a dynamic and intricate network of protein filaments, is found within the cytoplasm of all cells, from bacteria and archaea to complex eukaryotes. This essential cellular component …

Tailoring genetic fusions of widely used actin localization reporters by constraining the mobility of the fluorescent proteins allows measurements of actin filament organization in living cells and ti...

The mechanical properties of cells are governed by the cytoskeleton, a dynamic network of actin filaments, intermediate filaments, and microtubules. Understanding the individual and collective mechani...