iiinova — where your digital self keeps evolving

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Geoff McFadden @fad1.bsky.social · 07/06/2026

Today marks 30 years since we identified the apicoplast, a relict plastid in human and animal parasites (PMID 8632819). Apicoplasts are the target of the widely used antimalarial prophylactic doxycycline, which has saved many thousands of malaria infections.

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Gordon and Betty Moore Foundation @moorefound.bsky.social · 01/05/2026

New funding opportunity from the Symbiosis in Aquatic Systems Initiative. We’re inviting teams of two researchers to pursue ambitious, high-risk projects advancing aquatic symbiosis (marine + freshwater). Open globally. Details + how to apply:  moore.org/SymbiosisRFP #RFP #AquaticSymbiosis

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Philippa Matthews @pippa-matt.bsky.social · 01/05/2026

#WorldHepatitisSummit poster - our team shared #CommunityEngagement experience from our 'EVOLVE' #HBV project in #SouthAfrica to enhance interventions for #hepatitis #elimination. 🧪 👏 #WHS2026 #NoHep #MedSky #LiverSky @ahri-news.bsky.social @uclnews.bsky.social @crick.ac.uk doi.org/10.6084/m9.f...

Photo of team members Busangani and Luthando at the World Hepatitis Summit 2026, Bangkok

Photo of team members presenting our poster - you can view it on line here: https://doi.org/10.6084/m9.figshare.32143867

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Max Gutierrez @maxgg.bsky.social · 01/05/2026

Really important and relevant study in TB from @danbarberphd.bsky.social and colleagues. We need to re-think many assumptions. Nitric oxide production in mice has been a confounding factor. #tuberculosis

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Bella Rauch @rauchlab.bsky.social · 28/04/2026

Wan’t to be faculty at a collegial host-pathogen focused department in a beautiful bikable city with amazing food? This link is for you: facultycareers-ohsu.icims.com/jobs/39006/a...

A picture of the portland waterfront during cherry blossom time

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bishara marzook @ghostpathogen.bsky.social · 28/04/2026

Thank you Geoff!! Yes, can't wait to be back in the ocean regularly. Please do visit anytime, we'd love to host you!

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LSHTM Malaria Centre @lshtm-malaria.bsky.social · 27/04/2026

New research led @ndeyfa2.bsky.social, a PhD student @lshtm.bsky.social shows #malaria drug resistance isn’t driven by a single mutations but a complex combination of genetic changes that help parasites with legacy mutations survive newer treatments. Read more 👉 bit.ly/49aMu5W

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bishara marzook @ghostpathogen.bsky.social · 27/04/2026

For now, I want to say that the Epi-Api lab is looking for a PhD student! If you are interested in host-pathogen interactions focusing on host cell biology and molecular parasitology, do apply. GIMM's next PhD cohort begins Feb 2027. Applications due May 3. Please share! gimm.pt/news/join-th...

gimm.pt

Join the 2027 GIMM PhD Program – GIMMJoin the 2027 GIMM PhD Program – GIMMsearch

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bishara marzook @ghostpathogen.bsky.social · 27/04/2026

I am super excited to get started on a new chapter, but hope to never forget all the people who helped write this story so far. I have learned so much about science and myself, and look forward to putting it all into practice (and continuing to grow as a scientist and mentor as well!)

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bishara marzook @ghostpathogen.bsky.social · 27/04/2026

Hi all, I'd like to share some news - I will soon be moving to Lisbon, Portugal to start my very own lab @gimminstitute.bsky.social! The Epithelial Biology of Apicomplexan Infections lab (Epi-Api lab for short) will focus on the special relationship between #epithelial cells and #Cryptosporidium.

Picture of Bishara standing by a coastline at daytime, with a blue-green sea and palm trees in the background. She is holding a pastel de nata (Portuguese custard tart) and smiling.

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Raquel Fueyo @fueyoraquel.bsky.social · 28/11/2025

The IMPRS-BAC is an outstanding PhD program in Europe. And the endogenous retroviruses in development... what can I say? So much exciting biology to uncover! 🦠🧬#TEsky #StemCells Read the instructions and apply! ⬇️⬇️⬇️

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bishara marzook @ghostpathogen.bsky.social · 26/11/2025

There's still time to register for CoccidiaUK in London - it's going to be a jam-packed two days of talks by early-career parasitologists, a knowledge transfer session, plus trivia and prizes! It's @crick.ac.uk (very central) & we're cooking up some fun swag :) www.eventbrite.co.uk/e/coccidiauk...

eventbrite.co.uk

CoccidiaUK 2025

A biannual gathering of parasitologists from across the UK to discuss all things coccidian!

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bishara marzook @ghostpathogen.bsky.social · 14/10/2025

hahaha, well now it's definitely going on a sticker or t-shirt! Yay, can't wait!

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bishara marzook @ghostpathogen.bsky.social · 14/10/2025

There will be talks, discussion sessions, and ice-skating to get into the winter spirit! We @saterialelab.bsky.social can't wait.

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bishara marzook @ghostpathogen.bsky.social · 14/10/2025

Who-cysts? OOCYSTS! That's right, it's almost time for ❄️Coccidia UK 2025❄️ Your one-stop shop (/conference) for all like-minded sporulating apicomplexan parasites! This year we're in London @crick.ac.uk, looking forward to welcoming parasitologists from across the UK. Register- tinyurl.com/4ny5bwu2

tinyurl.com

CoccidiaUK 2025 registration

DEADLINE FOR ABSTRACT SUBMISSION: NOVEMBER 7th Event Timing: December 8th 9am-5pm December 9th 9am-12pm Event Address: The Francis Crick Institute Questions? please email ada...

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bishara marzook @ghostpathogen.bsky.social · 25/07/2025

Thanks Steph!! Yes loads more work to be done

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bishara marzook @ghostpathogen.bsky.social · 25/07/2025

Yes the publishing process was an insightful journey indeed! Grateful to the editors and reviewers for valuing this dataset and outcomes :)

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Kurt Ward @keward.bsky.social · 05/07/2025

My background is in molecular microbiology and parasitology, with a focus on malaria drug resistance. I’ve worked across international collaborations, mentored, and published in high-impact journals. Open to research, project-management, or education-focused roles in academia, govt or industry.

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Kurt Ward @keward.bsky.social · 05/07/2025

I’ve recently been made redundant from my role at UNSW due to the NIH’s decision to cancel foreign subawards. It’s an unfortunate situation affecting a lot of great researchers, and I’m now on the lookout for something new. If anyone knows of any molecular biologist roles coming up, let me know!

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bishara marzook @ghostpathogen.bsky.social · 24/07/2025

Oh, and a big thank you to our reviewers! The paper really benefited from them pushing us to explore and contextualise the data more deeply, so we thank them for their contributions and acknowledge their labour for the science we all love.

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bishara marzook @ghostpathogen.bsky.social · 24/07/2025

In these taxing times, I can only say that I count myself extremely fortunate to get to do what I love with people who make it worthwhile. I would not be here if not for them. I hope I can continue to do so and bring more people along on this continuing Crypto voyage.

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bishara marzook @ghostpathogen.bsky.social · 24/07/2025

Thankful to everyone in @saterialelab.bsky.social for making this journey so enjoyable, especially to Adam for giving me a shot on this huge project and guiding it through to the end. And of course the High-Throughput Screening team @crick.ac.uk for their invaluable expertise

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bishara marzook @ghostpathogen.bsky.social · 24/07/2025

We used this large dataset this created to discover some interesting host cell biology, unexpected Crypto biology, and even potentially a new host-directed treatment for this deadly disease. You can read the full thread about our findings here: bsky.app/profile/ghos... #MicroSky

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bishara marzook @ghostpathogen.bsky.social · 24/07/2025

We asked what happens if you disable almost every protein-coding human gene by CRISPR-Cas9 one by one in epithelial cells, infect those cells with the intestinal parasite #Cryptosporidium, and observe the resulting infection phenotypes by high-content microscopy to map the parasite's dependencies.

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Prof Jenny Rohn @jennyrohn.bsky.social · 21/07/2025

Last chance to apply for great research tech #job in my friendly lab @uclmedsci.bsky.social in London! Cutting-edge organoid and microbiology work seeking to understand how probiotic bacteria might be deployed to fight urinary infection #UTI. Closes 23 July #UTISky www.jobs.ac.uk/job/DNQ902/r...

jobs.ac.uk

Research Technician at UCL

Apply now for the Research Technician role on jobs.ac.uk - the leading job board for higher education jobs. View details.

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robmoon.bsky.social @robmoon.bsky.social · 19/07/2025

For those interested in Masters in lab and field based research in infectious disease we have 3 fantastic programmes to choose from MSc Immunology, medical parasitology and entomology and medical microbiology. They benefit from very flexible module choices and summer projects in UK and abroad!

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The Carlson Lab @ Yale @carlsonlab.bsky.social · 14/07/2025

Open call: If you are a researcher working on a project estimating a cause-specific burden of disease attributable to climate change at regional to global scales, please reach out! We're looking for researchers who might be interested in joining a new collaborative network / workshop series.

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Maria Bernabeu @mariabernabeu.bsky.social · 11/07/2025

Pre-print alert 🚨: We have developed 2D and 3D stable iPSC endothelial-differentiation models through dox inducible ETS expression. We demonstrate endothelial identity and used these models for studying malaria pathogenesis research. www.biorxiv.org/content/10.1...

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Marketa Novotna @marketanovotna.bsky.social · 06/07/2025

I used inducible CRISPR/Cas9 to make Trypanosoma brucei cell line that allowed me to edit originally muti-copy histone gene. We uncovered a novel role of H4 histone tail in gene regulation. I enjoyed working on this exciting project with @joanarcf.bsky.social, a great mentor. doi.org/10.1038/s414...

nature.com

Precision-edited histone tails disrupt polycistronic gene expression controls in trypanosomes - Nature Communications

Transcription in trypanosomatids, such as Trypanosoma brucei, is predominantly polycistronic and involves unconventional RNA polymerase II promoters. This study uses precision gene editing, site-satur...

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bishara marzook @ghostpathogen.bsky.social · 15/06/2025

Very cool work! More proof we have a lot to learn about actin and associated nucleation factors from apicomplexans :)

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bishara marzook @ghostpathogen.bsky.social · 02/02/2025

Woody Guthrie's guitar... hello

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bishara marzook @ghostpathogen.bsky.social · 14/06/2025

Honoured to have been invited to give a hallowed GRiP-ing seminar yesterday in Glasgow! Thanks @abhinay.bsky.social for the invite and @uofgsii.bsky.social for hosting me! Now enjoying the classic Glaswegian weather 😁 (yesterday was beautiful though!)

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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 10/06/2025

90% of you probably don’t need to read this. But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy. It’s about sharing something hard to say out loud; partly to heal, partly in case someone needs to hear it too. (1/3) tinyurl.com/DudinO

cell.com

Omaya Dudin

Interview with Omaya Dudin, who uses Ichthyosporea as models to study how and why unicellular organisms evolved multicellularity at the University of Geneva.

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Geoff McFadden @fad1.bsky.social · 08/06/2025

We are developing a simple, very cheap, low tech way to reduce malaria transmission. Instead of giving the antimalarials to people, we give them to the mosquitoes that spread the parasite. How do we drug a mosquito? Read on. www.sciencedirect.com/science/arti...

sciencedirect.com

Identifying antimalarials that disrupt malaria parasite transmission when fed to the mosquito

A decade-long decline in malaria cases has plateaued, primarily due to parasite drug resistance and mosquito resistance to insecticides used in bed ne…

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Mark A. Hanson @hansonmark.bsky.social · 03/06/2025

URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯 Any lab using @flybase.bsky.social please donate using the link in post below. This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.

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bishara marzook @ghostpathogen.bsky.social · 03/06/2025

Had a great time at this, learned so much! Thank you again for having a parasitologist amongst you. Looking forward to more host-pathogen interaction interactions 😁

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veupathdb.org @veupathdb.org · 02/06/2025

Make open access to tools and data part of your annual giving by making a tax deductible donation to @veupathdb.org. 💙This resource simplifies and supercharges global infectious disease research. Need more reasons to support VEuPathDB? Here's a short list: veupathdb.org/veupathdb/ap...

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bishara marzook @ghostpathogen.bsky.social · 30/05/2025

"Journal club" aka science hermeneutics

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Dave Barry @david-j-barry.bsky.social · 30/05/2025

Need help with bioimage analysis? Contact the UK Euro-BioImaging Node to see how we can help! www.eurobioimaging-access.eu/nodes/uk-node

eurobioimaging-access.eu

Euro-BioimagingEuro-BioImaging

The European Research Infrastructure for Imaging Technologies in Biological and Biomedical Sciences

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Leading Edge Fellows Program @leadingedgeprogram.bsky.social · 27/05/2025

We are thrilled to announce the 2025 Leading Edge Fellows! 40 outstanding postdoctoral fellows doing pioneering research in a wide range of biological and biomedical disciplines. Learn more about these exceptional scientists: www.leadingedgesymposium.org/fellows

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The Francis Crick Institute @crick.ac.uk · 27/05/2025

Crick researchers have shown how the bacteria causing tuberculosis can directly cross the brain’s protective barrier, causing meningitis in up to 10% of cases. www.crick.ac.uk/news/2025-05...

crick.ac.uk

Scientists explore how TB bacteria enter the brain

Researchers at the Francis Crick Institute have shown how the bacteria causing tuberculosis (TB) directly cross the brain’s protective barrier, causing meningitis, a very severe form of the disease th...

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British Infection Association @biainfection.bsky.social · 22/05/2025

Round 2 of the BIA Travel Awards are now open. If you are a trainee based in the UK or Ireland who has had an abstract accepted for a conference, find out more and apply before the closing date on 30th June 2025 👉 www.britishinfection...

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