aga-gastro.bsky.social @aga-gastro.bsky.social · 02/10/2026🌟 Study finds neutrophil-driven trogocytosis in pancreatic ductal adenocarcinoma liver metastases restrains immunosuppressive macrophage polarization and limits metastatic progression. 🔗 ow.ly/pNLK50ZSiWq 010
aga-gastro.bsky.social @aga-gastro.bsky.social · 30/09/2026Systematic review and meta-analysis of randomized controlled trials found very low-quality evidence that fecal microbiota transplantation reduced #IBS symptoms. Learn more at ow.ly/MPXB50ZSiIw 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 28/09/2026Beyond adenoma count: Both number and size shape future risk. Small (6–9mm) adenomas carry higher risk, supporting more refined colonoscopy surveillance strategies. Click the link to read more: 🔗 ow.ly/OEns50ZShNv 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 23/09/2026A significant factor in the pathogenesis of fecal incontinence (FI) is lumbar and sacral plexus neuropathy affecting the anorectum. Translumbosacral Neuromodulation Therapy (TNT) is a novel treatment for FI. 🔗 ow.ly/IRyV50ZNu7U 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 21/09/2026The October Editor's Essential Reading finds β-glucan and inulin estimated intake are associated with reduced risk of #CrohnsDisease, improved gut barrier and systemic inflammation markers, and multi-omic signatures in a high-risk cohort. 🔗 Read more at ow.ly/L1hQ50ZNtRa 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 18/09/2026📣 New in #Gastroenterology: studies on adenoma risk, dietary fiber and Crohn's disease, FMT for #IBS, KRAS-targeted pancreatic cancer therapy, and nutrition in the GLP-1 era. Read the October issue here: 🔗 ow.ly/9t0i50ZNuK1 001
aga-gastro.bsky.social @aga-gastro.bsky.social · 16/09/2026GI complications are common in systemic sclerosis and can impair nutrition and quality of life. Treatment remains largely symptomatic and empiric, underscoring the need for clinical trials. 🔗 ow.ly/bB4U50ZNn35 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 15/09/2026🌟 This #PeerReviewWeek, we recognize Sunny Chung, one of our top reviewers! He conducts peer reviews to support high-quality science, provide constructive feedback, and help authors strengthen their work. Thank you, Dr. Chung, for your dedication. 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 14/09/2026👧 How should H. pylori-associated disease be managed in children? This Gastro Grand Rounds article explores clinical considerations that support individualized care beyond a one-size-fits-all approach: ow.ly/rmPV50ZL2qN 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 14/09/2026📖 It’s #PeerReviewWeek! We're celebrating all the reviewers dedicated to helping AGA publish quality research. 🥳 Watch for journal posts this week as we recognize their impact and reflect on the theme of volume, speed, and quality. 🧠 Learn more: ow.ly/F0tu50ZNnS6 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 11/09/2026🐁 Years before #CrohnsDisease diagnosis, individuals' stool promotes more severe #colitis in germ-free mice. Shared metabolic signatures suggest that early microbiome changes may drive inflammation. 🔗 ow.ly/VkV050ZL1VM 131
aga-gastro.bsky.social @aga-gastro.bsky.social · 09/09/2026Risankizumab remains effective for achieving clinical, endoscopic, radiographic, and biomarker outcomes in #CrohnsDisease, even after ustekinumab treatment exposure and amongst primary non-responders to UST. Read more at ow.ly/iMph50ZL28n 010
aga-gastro.bsky.social @aga-gastro.bsky.social · 04/09/2026💡Adding a persistence feature to a probiotic enhances its efficacy for #colitis treatment, enhancing future human and veterinary therapeutic applications. 🔗 ow.ly/NpT450ZHksG 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 02/09/2026⭐ Up to one-third of patients with #IBD in remission have IBS-like symptoms. A new Rome Foundation–IOIBD consensus defines this phenotype and outlines diagnostic and treatment strategies: ow.ly/rFZt50ZHkfx 020
aga-gastro.bsky.social @aga-gastro.bsky.social · 31/08/2026📈 Which strategies best increase #colorectalcancer screening? Patient navigation and mailed FIT outreach lead the way, with educational multimedia emerging as a scalable option. Click the link to read more: 🔗 ow.ly/6QU050ZHjXc #CRC 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 28/08/2026Nordic case-control study finds that achalasia is strongly associated with esophageal squamous cell carcinoma. The association with adenocarcinoma is weaker and largely explained by reflux. Click the link to read more: 🔗 ow.ly/ijNk50ZEUY0 010
aga-gastro.bsky.social @aga-gastro.bsky.social · 27/08/2026💚 A randomized, sham-controlled trial demonstrated that G-POEM significantly improved gastric emptying and reduced gastroparesis symptoms in patients with diabetic gastroparesis. Explore the findings here: 🔗 ow.ly/kwcG50ZG6WH #GastroparesisAwarenessMonth 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 26/08/2026🧠 Misfolded proteins in the gut can predict future neurodegenerative disease risk—years before clinical symptoms appear. Individuals with GI proteinopathy also, notably, had reduced survival. 🔗 ow.ly/SaqK50ZEULQ 020
aga-gastro.bsky.social @aga-gastro.bsky.social · 24/08/2026🌟 The September Editor's Essential Reading examines mid- to long-term outcomes of the MESOCOLIC trial evaluating extensive vs limited mesenteric excision in #CrohnsDisease. Learn more at ow.ly/ZtcO50ZETjk 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 21/08/2026📖 The September issue is now online! It includes: 🔷Research on achalasia and esophageal malignancies 🔷A systematic review of interventions for increasing #CRC screening uptake 🔷A strategy for enhancing the therapeutic potential of probiotics in #IBD 🔗https://ow.ly/x92b50ZC1IR 110
aga-gastro.bsky.social @aga-gastro.bsky.social · 20/08/2026💚 Ever wonder what delayed stomach emptying feels like? August is #GastroparesisAwarenessMonth 💚 👩⚕️ Gastroparesis can happen in anyone, and symptoms can come and go. Help us connect the patients and caregivers affected, and explore patient resources at ow.ly/g6cv50ZBUPY 032
aga-gastro.bsky.social @aga-gastro.bsky.social · 19/08/2026📸 Gastro Curbside Consult presents an unexplained coexisting injury of the liver, pancreas, and brain. Can you determine the diagnosis? ow.ly/Ow9g50ZAyo3 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 17/08/20261/ 💬 A new three-part commentary series in #Gastroenterology examines some of the most pressing questions in liver transplantation today. ⬇️ Join the conversation as experts share perspectives on where the field is now and where it may be headed next. #Hepatology 101
aga-gastro.bsky.social @aga-gastro.bsky.social · 14/08/2026If you read "A Randomized Double-Blind, Placebo-Controlled Dose–Response Study to Assess the Gluten Threshold Dose in Celiac Disease," check out the corresponding editorial discussing the use of the Interleukin-2 test. 🔗 ow.ly/ykW450ZybIr 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 12/08/2026In >11,000 ERCP patients, single-dose rectal NSAIDs were not associated with adverse renal outcomes, even among older adults and those with CKD. Read more at: 🔗 ow.ly/kMpt50ZybLr 010
aga-gastro.bsky.social @aga-gastro.bsky.social · 10/08/2026🫀 INTERBLEED international prospective cohort study examines cardiovascular outcomes following major gastrointestinal bleeding in patients with pre-existing cardiovascular disease. Read more at ow.ly/lkCk50Zy9mt 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 07/08/2026👧 In children with acute severe #ulcerativecolitis, intestinal ultrasound helped identify patients unlikely to respond to first-line therapy and at higher risk for colectomy. 🔗 ow.ly/BR6m50ZwBkl #PedsGI 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 05/08/2026🔎 How should T1b esophageal adenocarcinoma in a 64-year-old patient be managed? Gastro Grand Rounds article examines treatment options and the role of multidisciplinary care: ow.ly/1pyw50Zwmrq 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 03/08/2026🧬 A DNA/RNA test on bile duct samples detects cancer more accurately than standard methods, especially in high-risk patients, and identifies gene changes that can guide personalized treatment. 🔗 ow.ly/psVq50Zrr9r 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 31/07/2026Study finds reduced intestinal epithelial GPX4 expression as a predictor of #CrohnsDisease recurrence after ileocolonic resection. GPX4 improved risk prediction beyond clinical factors and emerged as a potential therapeutic target, with selenium restoring GPX4 and reducing enteritis in mice. 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 29/07/2026🌟 153 gluten and placebo challenges from 1000mg to 1mg were given to people with #CeliacDisease. Study found that an eliciting dose did not result in an immune response in 95% (ED5) of participants. 🔗 Read more at ow.ly/TlxT50ZrqI2 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 27/07/2026🧬 Review highlights how polygenic risk scores and key variants such as PNPLA3, TM6SF2, and HSD17B13 may improve risk stratification for fibrosis progression and cirrhosis in #MASLD and #ALD. 🔗 ow.ly/Bet650ZrqtZ 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 24/07/2026💡 Study finds f-Hb–guided surveillance after polypectomy optimizes colonoscopy use, lowers #CRC risk, and outperforms USMSTF and ESGE guidelines in FIT-based screening. Learn more at ow.ly/Ws4850ZrpBw 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 22/07/2026📣 The August issue of #Gastroenterology is now available online! Essential reading includes: 🔹 An assessment of gluten threshold in #CeliacDisease 🔹 A study on intestinal ultrasound and severe pediatric #IBD 🔹 Research on GI bleeding and cardiovascular outcomes 🔗 ow.ly/lqO850ZrpjC 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 20/07/2026Study finds that STING-deficient CAR-T cells + diABZI boost antitumor activity, increase CAR-T persistence, and improve tumor control in pancreatic cancer models, highlighting a potential new strategy for solid tumors. 🔗 ow.ly/JVzg50Zq3PM 020
aga-gastro.bsky.social @aga-gastro.bsky.social · 17/07/2026💡Recordings of motion-guided biofeedback using abdominothoracic wall reduced rumination, providing the first simple, mechanism-based behavioral therapy directly translated from rumination physiology. 👉 Learn more at ow.ly/th5P50ZmZsu 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 15/07/2026👶 Early life stress disrupts the gut-brain axis; reshapes enteric circuits, motility, and visceral pain via sex hormones and sympathetics, and link these mechanisms to #DGBI risk in human cohorts. 🔗 ow.ly/o5N550ZmZxa 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 13/07/2026Nationwide cohort of 16,000 Swedish patients with isolated ulcerative proctitis showed no increased risk of rectal cancer or high-grade dysplasia compared with the general population over the course of 10 years. 🔗 ow.ly/P6Uq50ZmZm6 #UlcerativeProctitis #ColorectalCancer 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 10/07/2026🩺 With #MASLD affecting nearly 1 in 3 U.S. adults, the AGA's updated Clinical Care Pathway incorporates the latest evidence on disease nomenclature, risk stratification, diagnosis, and treatment, including newly approved therapies. 🔗 ow.ly/5Gfz50ZkL4y 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 08/07/2026🧬 Commentary highlights how immunotherapy continues to transform care across metastatic, adjuvant, and neoadjuvant settings for patients with dMMR/MSI-H #colorectalcancer. 🔗 ow.ly/h61w50ZkKuv 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 06/07/2026While incidence has stabilized, prevalence continues to grow. An aging #IBD population will increasingly strain healthcare systems aiming to provide affordable, accessible, high-quality care. 🔗 ow.ly/mvj650ZkJS5 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 03/07/2026Defecation urgency in #IBS reflects distinct gut–brain mechanisms. Real-life and barostat-induced urgency show different symptom profiles and brain correlates. Click the link to read more: ow.ly/ppNp50ZiqUU 010
aga-gastro.bsky.social @aga-gastro.bsky.social · 01/07/2026Comparison of two #dose-intensification regimens in patients with #CrohnsDisease experiencing #LOR to #ustekinumab showed comparable low recapture of remission after 48 weeks. 🔗 ow.ly/1liv50ZiqS9 010
aga-gastro.bsky.social @aga-gastro.bsky.social · 29/06/2026Study finds ganglioside-mediated neural-acinar crosstalk facilitates pancreatic carcinogenesis via metaplastic niche remodeling. Read more at ow.ly/SzqW50ZiqJe 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 26/06/2026Potential celiac disease offers a unique window into early autoimmunity, before intestinal damage occurs. Only some individuals progress to celiac disease, highlighting opportunities for risk stratification and prevention. 🔗 ow.ly/xA7i50ZhmTK #CeliacDisease #Autoimmunity 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 24/06/2026💡 Immediate direct endoscopic necrosectomy achieved faster clinical success than the step-up approach with comparable safety. Despite requiring more procedures, it may be a reasonable option in selected patients. Read more at ow.ly/Z67v50Zghsv 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 22/06/2026📣 The July issue of #Gastroenterology is now online! Essential reading includes: 🔹New research on the microbiome and postoperative #CrohnsDisease recurrence 🔹An RCT of timing for pancreatic necrosectomy 🔹A brief report forecasting #IBD incidence around the globe 🔗 ow.ly/x7Rc50Zfiht 110
aga-gastro.bsky.social @aga-gastro.bsky.social · 19/06/2026🌟 For people with diabetes who suffer from severe stomach emptying problems, a new gentle endoscopic treatment called G-POEM eased symptoms and improved stomach function significantly. Read the full study here: ow.ly/IxEE50ZbTO1 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 18/06/2026Gastro has received a 2025 Impact Factor of 29.7! On behalf of Editors-in-Chief Paul Moayyedi & David Weinberg, thank you to our editors, authors, reviewers & readers for your continued support. ow.ly/c9co50ZenCT American Gastroenterological Association (AGA) ow.lyJust released: AGA journals receive new Impact Factor scoresThe American Gastroenterological Association (AGA) is the trusted voice of the GI community. AGA publishes top-tier journals, guidelines and patient education ... 000
aga-gastro.bsky.social @aga-gastro.bsky.social · 17/06/2026✔️ Lower ultra-processed food intake is linked to nearly 50% reduced 20-year IBD risk in Western populations! 🍏Public health efforts needed to cut UPFs for IBD prevention. Read more at ow.ly/z7Hm50ZbThf 000
