Sign in

Gary Morris

@gazz4science.bsky.social
876 followers 380 following 22 posts

Glial-vasculature interactions, pericytes & microglia, dementia & stroke at the University of Tasmania.

PostsRepliesMedia
Reposted by Gary Morris
Axel Montagne @axelmontagne.bsky.social · 22/07/2025
🚨 Review Alert *Walking on the tightrope: the shared roles of the bridging pericytes in the brain* Congratulations Audrey Chagnot!! 🥳 Bias aside, this feels like a really meaningful piece for the cerebrovascular field! 😊 www.frontiersin.org/journals/cel...
frontiersin.org
Frontiers | Walking on the tightrope: the shared roles of the bridging pericytes in the brain
The vasculature of the central nervous system (CNS) is a highly specialized structure that delivers oxygen and nutrients to energy-demanding neural cells whi...
0187
Reposted by Gary Morris
Baptiste Lacoste @blacoste.bsky.social · 04/07/2025
Microglial control of cerebral capillary basal tone. Congrats to @eyolab.bsky.social & team ! #cerebrovascular
nature.com
Microglial cyclooxygenase-1 modulates cerebral capillary basal tone in vivo in mice - Nature Communications
The role of myeloid cells in vascular regulation remains incompletely understood. Here, the authors show that microglia are the only myeloid cells that localize to capillaries and that they maintain b...
0146
Reposted by Gary Morris
Søren Grubb @sorengrubb.bsky.social · 10/06/2025
🐭🧠 #PrecapillarySphincters (PS) at the #arteriole–#capillary junction rapidly dilate ~30% in seconds during #SensoryStimulation—regulating #capillary #BloodFlow dynamically. Here we investigated whether they protect downstream microvessels during abrupt #BloodPressure surges 🧪🧵
Showing how a precapillary sphincter dilates during high blood pressure
2208
Reposted by Gary Morris
Baptiste Lacoste @blacoste.bsky.social · 27/01/2025
New study about the role of microglia in regulating #cerebrovascular function, with an interesting twist on purineric signaling doi.org/10.1038/s414...
doi.org
Microglia modulate the cerebrovascular reactivity through ectonucleotidase CD39 - Nature Communications
Microglia and border-associated macrophages play a role in regulating cerebral blood flow (CBF), but the underlying mechanisms are unclear. Here, the authors show a role for microglial CD39 in the reg...
0134
Reposted by Gary Morris
Nature Neuroscience @natneuro.nature.com · 07/01/2025
Mice lacking microglia (Csf1r∆FIRE/∆FIRE) have normal -synapse number and maturation -seizure susceptibility and hippocampal-prefrontal cortex coherence -segregation of inputs into the lateral geniculate nucleus -neuronal and astrocytic gene expression www.nature.com/articles/s41...
nature.com
Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus - Nature Neuroscience
Microglia are proposed to have a role in brain development through synaptic engulfment and paracrine signaling. O’Keeffe et al. show that certain neurodevelopmental processes attributed to microglia c...
36930
Gary Morris @gazz4science.bsky.social · 04/12/2024
Had a fantastic week at #ANS2024 with Australasian Neuroscience colleagues talking #microglia, #pericytes and #TasmanianDevils. Look forward to seeing you all again in #Hobart for #ANS2025!
0141
Gary Morris @gazz4science.bsky.social · 29/11/2024
Here's a fun one for #FluorescenceFriday. Did you know #marsupials have an entirely different CNS vascular anatomy to most animals? Arterioles and venules enter the brain and branch in unison, terminating at capillary loops. Check out this example from a #TasmanianDevil brain! (1/2)
2469
Reposted by Gary Morris
Søren Grubb @sorengrubb.bsky.social · 26/11/2024
Here we show how #microglia contact #pericytes and #endothelialcells in the #venule end of the #capillary bed. Note also how a #primarycilium of an #interneuron invaginates the microglia. But why? 🤔 journals.sagepub.com/doi/full/10.... @gazz4science.bsky.social
33413
Gary Morris @gazz4science.bsky.social · 21/11/2024
Lovely new review to help identify features of microglia in EM images!
0111
Gary Morris @gazz4science.bsky.social · 19/11/2024
Calling all #pericyte researchers! Here's a list of us to start a community on Bluesky. Please feel free to reply to get added and share with your colleagues as more join! go.bsky.app/GhVdxzC
9198
Reposted by Gary Morris
Monica Carson @brainimmunity.bsky.social · 17/11/2024
some great starter packs for the #glia, #astrocyte, #oligodendrocyte, #microglia, #neuro researcher: gliasky, astrocytesky, microglia But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed? go.bsky.app/MHtJzeC
358749
Reposted by Gary Morris
Nicola Fattorelli @nicola-fattorelli.bsky.social · 17/11/2024
Microglia community, let’s start the discussion 🧠 follow the Microglia Starter Pack and ask @mancusorenzo.bsky.social to add your colleagues as they join Bluesky 🦋 go.bsky.app/DT3Cp4A
465735
Reposted by Gary Morris
Bryan D. James, PhD @bryandjames.bsky.social · 15/11/2024
Someone had to do it! I created a starter pack for #Alzheimer’s #dementia #ADRD researchers on Bluesky. Please let me know who I left out! Hoping more and more of us will join Bluesky go.bsky.app/22DpUEy
7313164
Reposted by Gary Morris
Shane Liddelow @liddelowsa.bsky.social · 14/11/2024
go.bsky.app/Lyzro3M !WELCOME! thought we might need a starter pack for all those coming over from the birdhouse - here's a GliaSky list. apologies for missing many of you - please do reply to get added and remember to repost so the newbies can find us!
9412999